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I. PROGRESS IN SECOND GENERATION OLIGOMER THERAPEUTICS

Synthesis and Properties of Oligoribonucleotide Analogues Having Amide (3″-CH2-CO-NH-5′) Internucleoside Linkages

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Pages 967-970 | Published online: 16 Aug 2006

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Read on this site (2)

Reiko Iwase, Takaaki Toyama & Kengo Nishimori. (2007) Solid-Phase Synthesis of Modified RNAs Containing Amide-Linked Oligoribonucleosides at Their 3′-End and Their Application to siRNA. Nucleosides, Nucleotides & Nucleic Acids 26:10-12, pages 1451-1454.
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Anna Winqvist & Roger Strömberg. (2001) PREPARATION OF 3′-C-BRANCHED URIDINE ANALOGUES, SUITABLE FOR CONVERSION INTO FUNCTIONALISED 3′-C-METHYLENE DERIVATIVES. Nucleosides, Nucleotides & Nucleic Acids 20:4-7, pages 1389-1392.
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Articles from other publishers (9)

Eriks Rozners. 2023. Handbook of Chemical Biology of Nucleic Acids. Handbook of Chemical Biology of Nucleic Acids 2339 2359 .
Eriks Rozners. 2022. Handbook of Chemical Biology of Nucleic Acids. Handbook of Chemical Biology of Nucleic Acids 1 21 .
Venubabu Kotikam & Eriks Rozners. (2020) Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs. Accounts of Chemical Research 53:9, pages 1782-1790.
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Daniel Mutisya, Chelliah Selvam, Benjamin D. Lunstad, Pradeep S. Pallan, Amanda Haas, Devin Leake, Martin Egli & Eriks Rozners. (2014) Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Research 42:10, pages 6542-6551.
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Paul Tanui, Scott D. Kennedy, Benjamin D. Lunstad, Amanda Haas, Devin Leake & Eriks Rozners. (2014) Synthesis, biophysical studies and RNA interference activity of RNA having three consecutive amide linkages. Org. Biomol. Chem. 12:8, pages 1207-1210.
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Alexander J. A. Cobb. (2007) Recent highlights in modified oligonucleotide chemistry. Organic & Biomolecular Chemistry 5:20, pages 3260.
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Qun Xu, Dace Katkevica & Eriks Rozners. (2006) Toward Amide-Modified RNA:  Synthesis of 3‘-Aminomethyl-5‘-carboxy-3‘,5‘-dideoxy Nucleosides. The Journal of Organic Chemistry 71:16, pages 5906-5913.
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Eriks Rozners & Qun Xu. (2003) Total Synthesis of 3‘,5‘-C-Branched Nucleosides. Organic Letters 5:21, pages 3999-4001.
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Eriks Rozners & Yang Liu. (2002) Toward Amide-Linked RNA Mimics:  Total Synthesis of 3‘-C Branched Uridine Azido Acid via an Ene−Iodolactonization Approach. Organic Letters 5:2, pages 181-184.
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