Advanced search
Publication Cover
Nucleosides and Nucleotides Volume 16, 1997 - Issue 7-9
Journal homepage
65
Views
22
CrossRef citations to date
0
Altmetric
V. NOVEL NUCLEOSIDES AND OLIGOMERS

New Unnatural L-Nucleoside Enantiomers:From Their Stereospecific Synthesis to Their Biological Activities

G. Gosselin Laboratoire Chimie Bioorganique, UMR CNRS 5625, Université Montpellier II, 34095, Montpellier
,
V. Boudou Laboratoire Chimie Bioorganique, UMR CNRS 5625, Université Montpellier II, 34095, Montpellier
,
J.-F. Griffon Laboratoire Chimie Bioorganique, UMR CNRS 5625, Université Montpellier II, 34095, Montpellier
,
G. Pavia Laboratoire Chimie Bioorganique, UMR CNRS 5625, Université Montpellier II, 34095, Montpellier
,
C. Pierra Laboratoire Chimie Bioorganique, UMR CNRS 5625, Université Montpellier II, 34095, Montpellier
,
J.-L. Imbach Laboratoire Chimie Bioorganique, UMR CNRS 5625, Université Montpellier II, 34095, Montpellier
,
A.-M. Aubertin Université Louis Pasteur, INSERM U 74, 67000, Strasbourg, France
,
R. F. Schinazi Veteran Affairs Medical Center, Emory University, School of Medicine, Decatur, GA-30033
,
A. Faraj University of Alabama, Department of Pharmacology, Birmingham, AL-35294, USA
&
J.-P. Sommadossi University of Alabama, Department of Pharmacology, Birmingham, AL-35294, USA
 show all
Pages 1389-1398 | Published online: 16 Aug 2006

Citations (22)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Daniel Ladurée, Christine Fossey, Zoica Delbederi, Elena Sugeac, Sylvie Schmidt, Geraldine Laumond & Anne-Marie Aubertin. (2005) Synthesis and antiviral activity of aryl phosphoramidate derivatives of β-D- and β-L-C-5-Substituted 2’,3’-didehydro-2’,3’-dideoxy-uridine bearing linker arms. Journal of Enzyme Inhibition and Medicinal Chemistry 20:6, pages 533-549.
Read now
Martin L. Bryant, Edward G. Bridges, Laurent Placidi, Abdesslem Faraj, Anna-Giulia Loi, Claire Pierra, David Dukhan, Gilles Gosselin, Jean-Louis Imbach, Brenda Hernandez, Amy Juodawlkis, Bud Tennant, Brent Korba, Paul Cote, Erika Cretton-Scott, Raymond F. Schinazi & Jean-Pierre Sommadossi. (2001) ANTI-HBV SPECIFIC β-L-2′-DEOXYNUCLEOSIDES. Nucleosides, Nucleotides & Nucleic Acids 20:4-7, pages 597-607.
Read now
Christophe Mathé & Gilles Gosselin. (2000) Synthesis and Antiviral Evaluation of the β-L-Enantiomers of Some Thymine 3′-Deoxypentofuranonucleoside Derivatives. Nucleosides, Nucleotides & Nucleic Acids 19:10-12, pages 1517-1530.
Read now
Z. Delbederi, C. Fossey, G. Fontaine, S. Benzaria, D. Gavriliu, A. Ciurea, B. Lelong, D. Ladurée, A.M. Aubertin & A. Kirn. (2000) Synthesis and Antiviral Activity of C-5 Substituted β-D- and β-L-D4T Analogues. Nucleosides, Nucleotides & Nucleic Acids 19:9, pages 1441-1461.
Read now
Arnaud Marchand, Christophe Mathé, Jean-Louis Imbach & Gilles Gosselin. (2000) Synthesis and Antiviral Evaluation of Unnatural β-L-Enantiomers of 3′-Fluoro- and 3′-Azido-2,3′-dideoxyguanosine Derivatives. Nucleosides, Nucleotides & Nucleic Acids 19:1-2, pages 205-217.
Read now
Valérie Boudou, Jean-Louis Imbach & Grilles Gosselin. (1999) Synthesis and Biological Evaluation of 9-(β-L-Arabinofuranosyl)Adenine. Nucleosides and Nucleotides 18:11-12, pages 2463-2473.
Read now
V. Boudou, G. Gosselin & J-L. Imbach. (1999) A New and Convenient Approach for the Synthesis of Ribo- and 2′-Deoxyribo-β-L-Furanonucleosides Starting From β-L-Xylofuranonucleosides. Nucleosides and Nucleotides 18:4-5, pages 607-609.
Read now
G. Gosselin, V. Boudou, J-F Griffon, G. Pavia, C. Pierra, J-L Imbach, A. Faraj & J-P Sommadossi. (1998) Unnatural β-L-Enantiomers of Nucleoside Analogues as Potent Anti-Hepatitis B Virus Agents. Nucleosides and Nucleotides 17:9-11, pages 1731-1738.
Read now

Articles from other publishers (14)

Daniela Perrone & Massimo L. Capobianco. 2013. Chemical Synthesis of Nucleoside Analogues. Chemical Synthesis of Nucleoside Analogues 473 534 .
Giuseppe Gumina, Youhoon Chong & Chung K. Chu. 2006. Deoxynucleoside Analogs In Cancer Therapy. Deoxynucleoside Analogs In Cancer Therapy 173 198 .
Sarah Gallois-Montbrun, Abdesslem Faraj, Edward Seclaman, Jean-Pierre Sommadossi, Dominique Deville-Bonne & Michel Véron. (2004) Broad specificity of human phosphoglycerate kinase for antiviral nucleoside analogs. Biochemical Pharmacology 68:9, pages 1749-1756.
Crossref
Barry M. Trost, Brian S. Brown, Ernest J. McEachern & Oliver Kuhn. (2003) Asymmetric Synthesis of Oxygen Heterocycles via Pd‐Catalyzed Dynamic Kinetic Asymmetric Transformations: Application to Nucleosides. Chemistry – A European Journal 9:18, pages 4442-4451.
Crossref
GIUSEPPE GUMINA, YONGSEOK CHOI & CHUNG K. CHU. 2003. Antiviral Nucleosides. Antiviral Nucleosides 1 76 .
Martin L. Bryant, Edward G. Bridges, Laurent Placidi, Abdesslem Faraj, Anna-Giulia Loi, Claire Pierra, Samira Benzaria, David Dukhan, Gilles Gosselin, Jean-Louis Imbach, Brenda Hernandez, Amy Juodawlkis, Bud Tennant, Brent Korba, Paul Cote, Erika Cretton-Scott, Raymond F. Schinazi, Maureen Myers & Jean-Pierre Sommadossi. 2003. Frontiers in Viral Hepatitis. Frontiers in Viral Hepatitis 245 261 .
Jean-Pierre Sommadossi. 2002. Recent Advances in Nucleosides: Chemistry and Chemotherapy. Recent Advances in Nucleosides: Chemistry and Chemotherapy 417 432 .
Martin L. BryantEdward G. BridgesLaurent PlacidiAbdesslem FarajAnna-Giulia Loi, Claire Pierra, David Dukhan, Gilles GosselinJean-Louis ImbachBrenda HernandezAmy JuodawlkisBud TennantBrent KorbaPaul CotePat Marion, Erika Cretton-ScottRaymond F. Schinazi & Jean-Pierre Sommadossi. (2001) Antiviral l -Nucleosides Specific for Hepatitis B Virus Infection . Antimicrobial Agents and Chemotherapy 45:1, pages 229-235.
Crossref
Dean V. Johnson, Roland Fischer & Herfried Griengl. (2000) A Novel Stereoselective Access to Substituted l-2-Deoxypentono-1,4-lactones and l-2-Deoxypentoses. Tetrahedron 56:47, pages 9289-9295.
Crossref
Laurent PlacidiErika Cretton-ScottGilles Gosselin, Claire Pierra, Raymond F. Schinazi, Jean-Louis Imbach, Mahmoud H. el KouniJean-Pierre Sommadossi. (2000) Intracellular Metabolism of β- l -2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity . Antimicrobial Agents and Chemotherapy 44:4, pages 853-858.
Crossref
Barry M. Trost & Lara S. Kallander. (1999) A Versatile Enantioselective Strategy Toward l - C -Nucleosides:  A Total Synthesis of l -Showdomycin . The Journal of Organic Chemistry 64:15, pages 5427-5435.
Crossref
Albert H. Soloway, Werner Tjarks, Beverly A. Barnum, Feng-Guang Rong, Rolf F. Barth, Iwona M. Codogni & J. Gerald Wilson. (1998) The Chemistry of Neutron Capture Therapy. Chemical Reviews 98:4, pages 1515-1562.
Crossref
G. GOSSELIN, V. BOUDOU, J.‐F. GRIFFON, G. PAVIA, C. PIERRA, J.‐L. IMBACH, A.‐M. AUBERTIN, R. F. SCHINAZI, A. FARAJ & J.‐P. SOMMADOSSI. (2010) ChemInform Abstract: New Unnatural L‐Nucleoside Enantiomers: From Their Stereospecific Synthesis to Their Biological Activities.. ChemInform 29:12.
Crossref
George W. Koszalka, Susan M. Daluge & F. Leslie Boyd. 1998. 163 171 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.