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Journal of Biomolecular Structure and Dynamics Volume 15, 1997 - Issue 2
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Original Articles

Use of Chemically Modified Nucleotides to Determine a 62-Nucleotide RNA Crystal Structure: A Survey of Phosphorothioates, Br, Pt and Hg

Carl C. Correli The Howard Hughes Medical Institute; Department of Molecular Biophysics and Biochemistry
,
Betty Freeborn Department of Chemistry, Yale University, 266 Whitney Avenue, New Haven, CT, 06520-8114, USA
,
Peter B. Moore Department of Molecular Biophysics and Biochemistry; Department of Chemistry, Yale University, 266 Whitney Avenue, New Haven, CT, 06520-8114, USA
&
Thomas A. Steitz The Howard Hughes Medical Institute; Department of Molecular Biophysics and Biochemistry; Department of Chemistry, Yale University, 266 Whitney Avenue, New Haven, CT, 06520-8114, USA
Pages 165-172 | Received 21 Jun 1997, Published online: 21 May 2012

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Ella Czarina Morishita. (2023) Discovery of RNA-targeted small molecules through the merging of experimental and computational technologies. Expert Opinion on Drug Discovery 18:2, pages 207-226.
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Articles from other publishers (27)

Tuomas A. Lönnberg, Madhuri A. Hande & Dattatraya U. Ukale. 2022. Comprehensive Organometallic Chemistry IV. Comprehensive Organometallic Chemistry IV 146 182 .
Dattatraya Ukale & Tuomas Lönnberg. (2021) Organomercury Nucleic Acids: Past, Present and Future. ChemBioChem 22:10, pages 1733-1739.
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Konrad Kowalski. (2021) Organometallic nucleosides—Synthesis, transformations, and applications. Coordination Chemistry Reviews 432, pages 213705.
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Joel Harp, Pradeep Pallan & Martin Egli. (2016) Phosphorus SAD Phasing for Nucleic Acid Structures: Limitations and Potential. Crystals 6:10, pages 125.
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Dattatraya Ukale, Vaishali S. Shinde & Tuomas Lönnberg. (2016) 5-Mercuricytosine: An Organometallic Janus Nucleobase. Chemistry - A European Journal 22:23, pages 7917-7923.
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Blaine H. M. Mooers. 2015. RNA-RNA Interactions. RNA-RNA Interactions 191 216 .
Jinwei Zhang & Adrian R Ferré-D’Amaré. (2014) New molecular engineering approaches for crystallographic studies of large RNAs. Current Opinion in Structural Biology 26, pages 9-15.
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Joseph E. Wedekind, Joseph A. Liberman, Jermaine L. Jenkins & Mohammad Salim. 2014. Chemical Biology of Nucleic Acids. Chemical Biology of Nucleic Acids 423 440 .
Blaine H.M. Mooers. (2009) Crystallographic studies of DNA and RNA. Methods 47:3, pages 168-176.
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Bernhard Lippert. 2008. Nucleic Acid–Metal Ion Interactions. Nucleic Acid–Metal Ion Interactions 39 74 .
Kwaku Dayie. (2008) Key Labeling Technologies to Tackle Sizeable Problems in RNA Structural Biology. International Journal of Molecular Sciences 9:7, pages 1214-1240.
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Amanda Y. Keel, Robert P. Rambo, Robert T. Batey & Jeffrey S. Kieft. (2007) A General Strategy to Solve the Phase Problem in RNA Crystallography. Structure 15:7, pages 761-772.
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Corinne Buré, Bertrand Castaing, Catherine Lange & Agnès F. Delmas. (2006) Location and base selectivity on fragmentation of brominated oligodeoxynucleotides. Journal of Mass Spectrometry 41:1, pages 84-90.
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David J. Proctor, Elzbieta Kierzek, Ryszard Kierzek & Philip C. Bevilacqua. (2003) Restricting the Conformational Heterogeneity of RNA by Specific Incorporation of 8-Bromoguanosine. Journal of the American Chemical Society 125:9, pages 2390-2391.
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Jennifer A. Doudna & Jamie H. Cate. 2001. RNA. RNA 49 60 .
Christopher Baugh, Dilârâ Grate & Charles Wilson. (2000) 2.8 Å crystal structure of the malachite green aptamer 1 1Edited by J. A. Doudna. Journal of Molecular Biology 301:1, pages 117-128.
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Nandita Sharma, Rolf Furter, Peter Kast & David A. Tirrell. (2000) Efficient introduction of aryl bromide functionality into proteins in vivo. FEBS Letters 467:1, pages 37-40.
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Jamie H. Cate & Jennifer A. Doudna. 2000. RNA - Ligand Interactions, Part A. RNA - Ligand Interactions, Part A 169 180 .
Joseph E. Wedekind & David B. McKay. 2000. RNA - Ligand Interactions, Part A. RNA - Ligand Interactions, Part A 149 168 .
Barbara L. Golden. 2000. RNA - Ligand Interactions, Part A. RNA - Ligand Interactions, Part A 124 132 .
Joseph A Ippolito & Thomas A Steitz. (2000) The structure of the HIV-1 RRE high affinity rev binding site at 1.6 Å resolution. Journal of Molecular Biology 295:4, pages 711-717.
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Stephen Cusack. (1999) RNA–protein complexes. Current Opinion in Structural Biology 9:1, pages 66-73.
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Jennifer A. Doudna & Jamie H. Cate. 1999. Comprehensive Natural Products Chemistry. Comprehensive Natural Products Chemistry 49 61 .
Joseph A. Ippolito & Thomas A. Steitz. (1998) A 1.3-Å resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation. Proceedings of the National Academy of Sciences 95:17, pages 9819-9824.
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Craig M. Ogata. (1998) MAD phasing grows up. Nature Structural Biology 5:8, pages 638-640.
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Sarah A Woodson & Neocles B Leontis. (1998) Structure and dynamics of ribosomal RNA. Current Opinion in Structural Biology 8:3, pages 294-300.
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Carl C. Correll, Betty Freeborn, Peter B. Moore & Thomas A. Steitz. (1997) Metals, Motifs, and Recognition in the Crystal Structure of a 5S rRNA Domain. Cell 91:5, pages 705-712.
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