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Journal of Biomolecular Structure and Dynamics Volume 21, 2004 - Issue 5
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Original Articles

Daunomycin Intercalation Stabilizes Distinct Backbone Conformations of DNA

Michael Trieb Institute of General Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020, Innsbruck, Austria
,
Christine Rauch Institute of General Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020, Innsbruck, Austria
,
Bernd Wellenzohn Institute of General Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020, Innsbruck, Austria
,
Fajar Wibowo Institute of General Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020, Innsbruck, Austria
,
Thomas Loerting Institute of General Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020, Innsbruck, Austria
,
Erwin Mayer Institute of General Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020, Innsbruck, Austria
&
Klaus R. Liedl Institute of General Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, A-6020, Innsbruck, Austria
 show all
Pages 713-724 | Received 19 May 2003, Published online: 15 May 2012

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Shirlene Jackson Beckford & DabneyW. Dixon. (2012) Molecular Dynamics of Anthraquinone DNA Intercalators with Polyethylene Glycol Side Chains. Journal of Biomolecular Structure and Dynamics 29:5, pages 1065-1080.
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Articles from other publishers (18)

Donald J. AbrahamMallory Pullman, Francisco León & Stephen J. Cutler. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 89 .
Guoxuan Sun, Pedro Ernesto de Resende, Paul Stapleton, Martyna Kuta, Xiangtao Wang, Shozeb Haider & Min Yang. (2017) Regioselective glycosylation of novobiocin alters activity. Carbohydrate Research 452, pages 116-121.
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T. Banerjee, S. Banerjee, S. Sett, S. Ghosh, T. Rakshit & R. Mukhopadhyay. (2016) Discriminating Intercalative Effects of Threading Intercalator Nogalamycin, from Classical Intercalator Daunomycin, Using Single Molecule Atomic Force Spectroscopy. PLOS ONE 11:5, pages e0154666.
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Attilio V. Vargiu & Alessandra Magistrato. (2014) Atomistic‐Level Portrayal of Drug–DNA Interplay: A History of Courtships and Meetings Revealed by Molecular Simulations. ChemMedChem 9:9, pages 1966-1981.
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Benjamin Doughty, Yi Rao, Samuel W. Kazer, Sheldon J. J. Kwok, Nicholas J. Turro & Kenneth B. Eisenthal. (2013) Binding of the Anti-Cancer Drug Daunomycin to DNA Probed by Second Harmonic Generation. The Journal of Physical Chemistry B 117:49, pages 15285-15289.
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Jia Sheng, Jianhua Gan & Zhen Huang. (2013) Structure-Based DNA-Targeting Strategies with Small Molecule Ligands for Drug Discovery. Medicinal Research Reviews 33:5, pages 1119-1173.
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Arnab Mukherjee & Wilbee D. Sasikala. 2013. Dynamics of Proteins and Nucleic Acids. Dynamics of Proteins and Nucleic Acids 1 62 .
Guang-Zhu Jin, Hai-Shan Jin & Li-Li Jin. (2011) Synthesis and antiproliferative activity of 1,4-bis(dimethylamino)-9,10-anthraquinone derivatives against P388 mouse leukemic tumor cells. Archives of Pharmacal Research 34:7, pages 1071-1076.
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Prashansa Agrawal, Sudhir Kumar Barthwal, Girjesh Govil & Ritu Barthwal. (2009) Studies on the interaction of adriamycin with d-(TGATCA)2 by proton nuclear magnetic resonance spectroscopy, time-resolved fluorescence measurement, diffusion ordered spectroscopy followed by structural refinement using restrained molecular dynamics approach. Journal of Molecular Structure 932:1-3, pages 67-83.
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Prashansa Agrawal, Sudhir Kumar Barthwal, Girjesh Govil & Ritu Barthwal. (2009) Solution studies on the complex of 4′-epiadriamycin-d-(CGATCG)2 followed by time-resolved fluorescence measurement, diffusion ordered spectroscopy and restrained molecular dynamics simulations. Bioorganic & Medicinal Chemistry 17:7, pages 2793-2811.
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Arnab Mukherjee, Richard Lavery, Biman Bagchi & James T. Hynes. (2008) On the Molecular Mechanism of Drug Intercalation into DNA: A Simulation Study of the Intercalation Pathway, Free Energy, and DNA Structural Changes. Journal of the American Chemical Society 130:30, pages 9747-9755.
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Ritu Barthwal, Prashansa Agrawal, A.N. Tripathi, Uma Sharma, N.R. Jagannathan & Girjesh Govil. (2008) Structural elucidation of 4′-epiadriamycin by nuclear magnetic resonance spectroscopy and comparison with adriamycin and daunomycin using quantum mechanical and restrained molecular dynamics approach. Archives of Biochemistry and Biophysics 474:1, pages 48-64.
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Christian Hertweck, Andriy Luzhetskyy, Yuri Rebets & Andreas Bechthold. (2007) Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork. Nat. Prod. Rep. 24:1, pages 162-190.
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Attilio V. Vargiu, Paolo Ruggerone, Alessandra Magistrato & Paolo Carloni. (2006) Anthramycin−DNA Binding Explored by Molecular Simulations. The Journal of Physical Chemistry B 110:48, pages 24687-24695.
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V. V. Kostjukov, V. I. Pahomov & L. N. Dimant. (2006) Structural characteristics of intercalation complex of deoxyheptanucleotide hairpin d(GCGAAGC) with anthracycline antibiotic daunomycin. Biopolymers and Cell 22:5, pages 339-349.
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Monica Jain, Sudhir Kumar Barthwal, Ritu Barthwal & Girjesh Govil. (2005) Restrained molecular dynamics studies on complex of adriamycin with DNA hexamer sequence d-CGATCG. Archives of Biochemistry and Biophysics 439:1, pages 12-24.
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Thomas E. CheathamIIIIII. 2005. 75 89 .
Thomas E CheathamIIIIII. (2004) Simulation and modeling of nucleic acid structure, dynamics and interactions. Current Opinion in Structural Biology 14:3, pages 360-367.
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