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Journal of Biomolecular Structure and Dynamics Volume 27, 2009 - Issue 2
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Original Articles

Binding of TCA to the Prion Protein: Mechanism, Implication for Therapy, and Application as Probe for Complex Formation of Bio-macromolecules

Christian Mangels Department of Biopolymers, University of Bayreuth Universitätsstrasse 30, 95440, Bayreuth, Germany
,
Andreas O. Frank Department of Biopolymers, University of Bayreuth Universitätsstrasse 30, 95440, Bayreuth, Germany
,
Jan Ziegler Department of Biopolymers, University of Bayreuth Universitätsstrasse 30, 95440, Bayreuth, Germany
,
Ralph Klingenstein Institute of Neuropathology, Heinrich-Heine-University, Moorenstr. 5, 40225, Düsseldorf, Germany
,
Kristian Schweimer Department of Biopolymers, University of Bayreuth Universitätsstrasse 30, 95440, Bayreuth, Germany
,
Dieter Willbold Institute for Physical Biology Heinrich-Heine-University Düsseldorf and Institute of Neuroscience and Biophysics 2 at the Research Centre, Jülich, 52425, Jülich, Germany
,
Carsten Korth Institute of Neuropathology, Heinrich-Heine-University, Moorenstr. 5, 40225, Düsseldorf, Germany
,
Paul Rösch Department of Biopolymers, University of Bayreuth Universitätsstrasse 30, 95440, Bayreuth, Germany
&
Stephan Schwarzinger Department of Biopolymers, University of Bayreuth Universitätsstrasse 30, 95440, Bayreuth, Germany
 show all
Pages 163-170 | Received 13 Feb 2009, Published online: 15 May 2012

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Atta Ahmad, ColinS. Burns, AnthonyL. Fink & VladimirN. Uversky. (2012) Peculiarities of Copper Binding to α-Synuclein. Journal of Biomolecular Structure and Dynamics 29:4, pages 825-842.
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Esmaeil Behmard, Parviz Abdolmaleki, Ebrahim Barzegari Asadabadi & Samad Jahandideh. (2011) Prevalent Mutations of Human Prion Protein: A Molecular Modeling and Molecular Dynamics Study. Journal of Biomolecular Structure and Dynamics 29:2, pages 379-389.
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Jiapu Zhang. (2011) The Structural Stability of Wild-type Horse Prion Protein. Journal of Biomolecular Structure and Dynamics 29:2, pages 369-377.
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Ping Li, Jian Jun Tan, Ming Liu, Xiao Yi Zhang, Wei Zu Chen & Cun Xin Wang. (2011) Insight into the Inhibitory Mechanism and Binding Mode Between D77 and HIV-1 Integrase by Molecular Modeling Methods. Journal of Biomolecular Structure and Dynamics 29:2, pages 311-323.
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Adeleh Divsalar, Ali Akbar Saboury, Leila Ahadi, Elham Zemanatiyar, Hassan Mansouri-Torshizi, Davood Ajloo & RamaswamyH. Sarma. (2011) Biological Evaluation and Interaction of a Newly Designed Anti-cancer Pd(II) Complex and Human Serum Albumin. Journal of Biomolecular Structure and Dynamics 29:2, pages 283-296.
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WilianA. Cortopassi, AlineA. Oliveira, AnaP. Guimarães, MagdalenaN. Rennó, AntonianaU. Krettli & Tanos C.C. França. (2011) Docking Studies on the Binding of Quinoline Derivatives and Hematin to Plasmodium Falciparum Lactate Dehydrogenase. Journal of Biomolecular Structure and Dynamics 29:1, pages 207-218.
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Zahra Omidvar, Kazem Parivar, Hamideh Sanee, Zeinab Amiri-Tehranizadeh, Ali Baratian, Mohammad Reza Saberi, Ahmad Asoodeh & Jamshidkhan Chamani. (2011) Investigations with Spectroscopy, Zeta Potential and Molecular Modeling of the Non-Cooperative Behaviour Between Cyclophosphamide Hydrochloride and Aspirin upon Interaction with Human Serum Albumin: Binary and Ternary Systems from the View Point of Multi-Drug Therapy. Journal of Biomolecular Structure and Dynamics 29:1, pages 181-206.
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Sudipta Pal, Mili Das, Rahul Banerjee & Dipak Dasgupta. (2011) Biphasic Association of T7 RNA Polymerase and a Nucleotide Analogue, Cibacron Blue as a Model to Understand the Role of Initiating Nucleotide in the Mechanism of Enzyme Action. Journal of Biomolecular Structure and Dynamics 29:1, pages 153-164.
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JaysonF. Varughese & Yumin Li. (2011) Molecular Dynamics and Docking Studies on Cardiac Troponin C. Journal of Biomolecular Structure and Dynamics 29:1, pages 123-135.
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AlexeiN. Pankratov, OlgaM. Tsivileva, BorisI. Drevko & ValentinaE. Nikitina. (2011) Compounds of the 1,5-di(4-R-phenyl)-3-selenopentanediones-1,5 series interaction with the Basidiomycete Lentinula edodes, lectins: Computations and Experiment. Journal of Biomolecular Structure and Dynamics 28:6, pages 969-974.
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MalihehS. Atri, AliA. Saboury, AliA. Moosavi-Movahedi, Bahram Goliaei, Yahya Sefidbakht, Hamid Hadi Alijanvand, Ahmad Sharifzadeh & Amir Niasari-Naslaji. (2011) Structure and Stability Analysis of Cytotoxic Complex of Camel α-Lactalbumin and Unsaturated Fatty Acids Produced at High Temperature. Journal of Biomolecular Structure and Dynamics 28:6, pages 919-928.
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TeodoricoC. Ramalho, MelissaS. Caetano, Daniela Josa, GustavoP. Luz, ElisangelaA. Freitas & Elaine F. F. da Cunha. (2011) Molecular Modeling of Mycobacterium Tuberculosis dUTpase: Docking and Catalytic Mechanism Studies. Journal of Biomolecular Structure and Dynamics 28:6, pages 907-917.
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Yue Wang, Fuyong Bian, Shengrong Deng, Qiang Shi, Maofa Ge, Shu Wang, Xingkang Zhang & Sichuan Xu. (2011) The Key Residues of Active Sites on the Catalytic Fragment for Paclitaxel Interacting with Poly (ADP-Ribose) Polymerase. Journal of Biomolecular Structure and Dynamics 28:6, pages 881-893.
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Mei Zhuohang, Liu Ji & Yu Hongwei. (2011) Modeling of Transition State by Molecular Dynamics. Prediction of Catalytic Efficiency of the Mutants of Mandelate Racemase. Journal of Biomolecular Structure and Dynamics 28:6, pages 871-879.
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Jiapu Zhang & David D.W. Liu. (2011) Molecular Dynamics Studies on the Structural Stability of Wild-type Dog Prion Protein. Journal of Biomolecular Structure and Dynamics 28:6, pages 861-869.
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YuDong Cai, JianFeng He & Lin Lu. (2011) Predicting Sumoylation Site by Feature Selection Method. Journal of Biomolecular Structure and Dynamics 28:5, pages 797-804.
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H. Vahedian-Movahed, M.R. Saberi & J. Chamani. (2011) Comparison of Binding Interactions of Lomefloxacin to Serum Albumin and Serum Transferrin by Resonance Light Scattering and Fluorescence Quenching Methods. Journal of Biomolecular Structure and Dynamics 28:4, pages 483-502.
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Zanxia Cao, Lei Liu & Jihua Wang. (2010) Effects of pH and Temperature on the Structural and Thermodynamic Character of a-syn12 Peptide in Aqueous Solution. Journal of Biomolecular Structure and Dynamics 28:3, pages 343-353.
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Zhiwei Yang, Nan Wu, Yujie Fu, Gang Yang, Wei Wang, Yuangang Zu & Thomas Efferth. (2010) Anti-Infectious Bronchitis Virus (IBV) Activity of 1,8-cineole: Effect on Nucleocapsid (N) Protein. Journal of Biomolecular Structure and Dynamics 28:3, pages 323-330.
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Christian Mangels, Ruth Kellner, Jürgen Einsiedel, PhilippR. Weiglmeier, Paul Rösch, Peter Gmeiner & Stephan Schwarzinger. (2010) The Therapeutically Anti-prion Active Antibody-fragment scFv-W226: Paramagnetic Relaxation-Enhanced NMR Spectroscopy aided Structure Elucidation of the Paratope-epitope Interface. Journal of Biomolecular Structure and Dynamics 28:1, pages 13-22.
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Articles from other publishers (1)

Phuhai Nguyen, Nassima Oumata, Flavie Soubigou, Justine Evrard, Nathalie Desban, Pascale Lemoine, Serge Bouaziz, Marc Blondel & Cécile Voisset. (2014) Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles. European Journal of Medicinal Chemistry 82, pages 363-371.
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