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Review Article

The Use of Topical Corticosteroids for Treatment of Dry Eye Syndrome

, MD ORCID Icon, , MD, PhD, , MD ORCID Icon & , MD
Pages 266-275 | Received 14 Apr 2017, Accepted 09 Jun 2017, Published online: 14 Sep 2017

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Alejandro Rodriguez-Garcia, Alejandro Babayan-Sosa, Arturo Ramirez-Miranda, Concepcion Santa Cruz-Valdes, Everardo Hernandez-Quintela, Julio C Hernandez-Camarena, Nallely Ramos-Betancourt, Regina Velasco-Ramos & Raul E Ruiz-Lozano. (2022) A Practical Approach to Severity Classification and Treatment of Dry Eye Disease: A Proposal from the Mexican Dry Eye Disease Expert Panel. Clinical Ophthalmology 16, pages 1331-1355.
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Kelly K Nichols, Eric D Donnenfeld, Charis Lau, Annie Syntosi, Paul Karpecki & John A Hovanesian. (2022) Reduction of Artificial Tears and Use of Adjunctive Dry Eye Therapies After Lifitegrast Treatment: Evidence from Clinical and Real-World Studies. Clinical Ophthalmology 16, pages 909-916.
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Philippe Daull, Takashi Nagano, Emilie Gros, Laurence Feraille, Stefano Barabino & Jean-Sébastien Garrigue. (2021) Ocular surface response of two preservative-free cylcosporine A emulsion eye drops in a mouse model of dry eye. Current Eye Research 46:8, pages 1096-1104.
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Alireza Shoari, Mohammad Javad Rasaee, Mozhgan Rezaei Kanavi, Sasha Afsar Aski & Raheleh Tooyserkani. (2021) In Vivo Effect of RSH-12, a Novel Selective MMP-9 Inhibitor Peptide, in the Treatment of Experimentally Induced Dry Eye Model. Current Eye Research 46:1, pages 7-13.
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Biljana Kuzmanović Elabjer, Leon Marković, Mirjana Bjeloš, Mladen Bušić, Daliborka Miletić & Eva Kos. (2020) A Retrospective Data Review Confirms That Topical Preservative-Free Hydrocortisone Improves Inflammation in Dry Eye Disease. Clinical Ophthalmology 14, pages 3691-3697.
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Articles from other publishers (26)

S. K. Zyryanov & O. I. Butranova. (2023) Topical glucocorticoids in ophthalmology: a comparative analysis of efficacy and safety. Russian Ophthalmological Journal 16:2, pages 166-172.
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Elisabeth M Messmer, Sajjad Ahmad, José M Benitez del Castillo, Ewa Mrukwa-Kominek, Maurizio Rolando, Oksana Vitovska & Christophe Baudouin. (2022) Management of inflammation in dry eye disease: Recommendations from a European panel of experts. European Journal of Ophthalmology 33:3, pages 1294-1307.
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Gholamreza Jafari, Heidar Raissi, Ali Saberinasab & Samaneh Pasban. (2023) Phosphatidylcholine in the tear film of the eye: Enhanced topical delivery of fluorometholone to the eye. Inorganic Chemistry Communications 150, pages 110506.
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A Tarakeswara Rao, Amit Gupta, Tulika Chauhan, Sayan Basu, Nitin Batra, Namrata Sharma, Virender S Sangwan, Vinay Gupta & Shoibal Mukherjee. (2023) Efficacy and safety of 0.05% micellar nano-particulate (MNP) cyclosporine ophthalmic emulsion in the treatment of moderate-to-severe keratoconjunctivitis sicca: a 12-week, multicenter, randomized, active-controlled trial. BMC Ophthalmology 23:1.
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Matthew T. Hirabayashi & Brad P. Barnett. (2023) Solving STODS—Surgical Temporary Ocular Discomfort Syndrome. Diagnostics 13:5, pages 837.
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Youngsub EomKyung Chul Yoon, Hong Kyun KimJong Suk SongJoon Young Hyon & Hyo Myung Kim. (2023) A Multicenter, Randomized, Double-Blind Evaluation of the Efficacy of TJO-087 Versus 0.05% Cyclosporine A in Moderate to Severe Dry Eye. Journal of Ocular Pharmacology and Therapeutics 39:1, pages 27-35.
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Youngsub Eom, Jong Suk Song & Hyo Myung Kim. (2022) Effectiveness of Topical Cyclosporin A 0.1%, Diquafosol Tetrasodium 3%, and Their Combination, in Dry Eye Disease. Journal of Ocular Pharmacology and Therapeutics 38:10, pages 682-694.
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Miłosz Caban, Wojciech Omulecki & Beata Latecka-Krajewska. (2022) Dry eye in Sjögren's syndrome – characteristics and therapy. European Journal of Ophthalmology 32:6, pages 3174-3184.
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Su-Hsun Liu, Ian J Saldanha, Alison G Abraham, Thanitsara Rittiphairoj, Scott Hauswirth, Darren Gregory, Cristos Ifantides & Tianjing Li. (2022) Topical corticosteroids for dry eye. Cochrane Database of Systematic Reviews 2022:10.
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Run Bai, Li-ping Liu, Zhen Chen & Qiong Ma. (2022) Cyclosporine (0.05%) Combined with Diclofenac Sodium Eye Drops for the Treatment of Dry Eye Disease. Journal of Ophthalmology 2022, pages 1-6.
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Stefano Barabino, Elisa Montaldo, Maria Cristina Mingari, Cosimo Mazzotta, Sebastiano Giuffrida & Maurizio Rolando. (2021) Is there a role for tapered topical dose steroidal treatment for dry eye disease? A randomized, pilot study. European Journal of Ophthalmology 32:4, pages 2452-2458.
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Tian-zuo Wang, Bin Guan, Xin-xin Liu, Lin-nan Ke, Jing-jie Wang & Kai-hui Nan. (2022) A topical fluorometholone nanoformulation fabricated under aqueous condition for the treatment of dry eye. Colloids and Surfaces B: Biointerfaces 212, pages 112351.
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Mohansrinivas Chennakesavalu, Sri Raghurama R. Somala, Sunil R. Dommaraju, Meghna Priyanka Peesapati, Kai Guo, Mark I. Rosenblatt, Jin-Hong Chang & Dimitri T. Azar. (2021) Corneal lymphangiogenesis as a potential target in dry eye disease - a systematic review. Survey of Ophthalmology 66:6, pages 960-976.
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Edward J. Holland, Mitchell A. Jackson, Eric Donnenfeld, Rebecca Piccolo, Alisa Cohen, Stefano Barabino, Maurizio Rolando & Francisco C. Figueiredo. (2021) Efficacy of Lifitegrast Ophthalmic Solution, 5.0%, in Patients With Moderate to Severe Dry Eye Disease. JAMA Ophthalmology 139:11, pages 1200.
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Renshu Zhang, Jianhong Zhou, Dan Lin, Yuhan Hu, Bo Jin, Yuqin Wang, Jiaqing Wang, Serhii Vakal & Xingyi Li. (2021) Dexamethasone-peptide prodrug supramolecular hydrogel effectively alleviates experimental autoimmune uveitis (EAU). Chemical Engineering Journal 421, pages 129623.
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Tzu-Yang Chen, Ching-Li Tseng, Chih-An Lin, Hua-Yang Lin, Parthiban Venkatesan & Ping-Shan Lai. (2021) Effects of Eye Drops Containing Hyaluronic Acid-Nimesulide Conjugates in a Benzalkonium Chloride-Induced Experimental Dry Eye Rabbit Model. Pharmaceutics 13:9, pages 1366.
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Minji Kim, Yonghoon Lee, Divy Mehra, Alfonso L Sabater & Anat Galor. (2021) Dry eye: why artificial tears are not always the answer. BMJ Open Ophthalmology 6:1, pages e000697.
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Stephanie Kourakis, Cara A. Timpani, Dean G. Campelj, Patricia Hafner, Nuri Gueven, Dirk Fischer & Emma Rybalka. (2021) Standard of care versus new-wave corticosteroids in the treatment of Duchenne muscular dystrophy: Can we do better?. Orphanet Journal of Rare Diseases 16:1.
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Gaia Favero, Enrico Moretti, Kristína Krajčíková, Vladimíra Tomečková & Rita Rezzani. (2021) Evidence of Polyphenols Efficacy against Dry Eye Disease. Antioxidants 10:2, pages 190.
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Shih-Lin Chen, Kuang-Chieh Hsueh & Pei-Ling Tang. (2021) Association between dry eye and traditional Chinese medicine body constitutions. Medicine 100:2, pages e24265.
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Giuseppe Giannaccare & Vincenzo Scorcia. (2020) False Myths versus Medical Facts: Ten Common Misconceptions Related to Dry Eye Disease. Biomedicines 8:6, pages 172.
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Bhavana Sharma, Deepak Soni, Harsha Saxena, LouisJ Stevenson, Samendra Karkhur, Brijesh Takkar & RasikB Vajpayee. (2020) Impact of corneal refractive surgery on the precorneal tear film. Indian Journal of Ophthalmology 68:12, pages 2804.
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Hyeyoon Goo, Hoon Kim, Jin-Chul Ahn & Kyong Jin Cho. (2019) Effects of Low-level Light Therapy at 740 nm on Dry Eye Disease In Vivo . Medical Lasers 8:2, pages 50-58.
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Jonathan Taniguchi & Ajay Sharma. (2019) Fluorometholone modulates gene expression of ocular surface mucins. Acta Ophthalmologica 97:8.
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Yu-Kai Kuo, I-Chan Lin, Li-Nien Chien, Tzu-Yu Lin, Ying-Ting How, Ko-Hua Chen, Gregory J. Dusting & Ching-Li Tseng. (2019) Dry Eye Disease: A Review of Epidemiology in Taiwan, and its Clinical Treatment and Merits. Journal of Clinical Medicine 8:8, pages 1227.
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Victor J. Drew, Ching-Li Tseng, Jerard Seghatchian & Thierry Burnouf. (2018) Reflections on Dry Eye Syndrome Treatment: Therapeutic Role of Blood Products. Frontiers in Medicine 5.
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