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Christine Shu Mei Lee, Amandeep Kaur, Samantha J. Montague, Sarah M. Hicks, Robert K. Andrews & Elizabeth E. Gardiner. (2023) Tissue inhibitors of metalloproteinases (TIMPs) modulate platelet ADAM10 activity. Platelets 34:1.
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Steven Bruzek, Marisol Betensky, Jorge Di Paola, Thomas Diacovo, Neil Goldenberg & Vera Ignjatovic. (2023) What can the plasma proteome tell us about platelets (and vice versa)?. Platelets 34:1.
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Mohammad Al-Tamimi, Jianlin Qiao & Elizabeth E. Gardiner. (2022) The utility of platelet activation biomarkers in thrombotic microangiopathies. Platelets 33:4, pages 503-511.
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Jianlin Qiao, Eimear Dunne, Bruce Wines, Dermot Kenny, Geraldine M. McCarthy, P. Mark Hogarth, Kailin Xu, Robert K. Andrews & Elizabeth E. Gardiner. (2020) Plasma levels of the soluble form of the FcγRIIa receptor vary with receptor polymorphisms and are elevated in rheumatoid arthritis. Platelets 31:3, pages 392-398.
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Alexandre Slater, Gina Perrella, Marie-Blanche Onselaer, Eleyna M Martin, Julia S Gauer, Rui-Gang Xu, Johan WM Heemskerk, Robert A S Ariëns & Steve P Watson. (2019) Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?. Platelets 30:3, pages 281-289.
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Richard Conway, Claire-Louise Murphy, Anne Madigan, Patricia Kavanagh, Liz Geraghty, Niamh Redmond, Laura Helbert, John J. Carey, Eimear Dunne, Dermot Kenny & Geraldine M. McCarthy. (2018) Increased platelet reactivity as measured by plasma glycoprotein VI in gout. Platelets 29:8, pages 821-826.
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Robert K. Andrews & Elizabeth E. Gardiner. (2017) Basic mechanisms of platelet receptor shedding. Platelets 28:4, pages 319-324.
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Madhumita Chatterjee & Meinrad Gawaz. (2017) Clinical significance of receptor shedding-platelet GPVI as an emerging diagnostic and therapeutic tool. Platelets 28:4, pages 362-371.
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Amanda E. Au & Emma C. Josefsson. (2017) Regulation of platelet membrane protein shedding in health and disease. Platelets 28:4, pages 342-353.
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Markus Bender, David Stegner & Bernhard Nieswandt. (2017) Model systems for platelet receptor shedding. Platelets 28:4, pages 325-332.
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J. M. Trevillyan, E. E. Gardiner, R. K. Andrews, A. Maisa, A. C. Hearps, M. Al-Tamimi, S. M. Crowe & J. F. Hoy. (2017) Decreased levels of platelet-derived soluble glycoprotein VI detected prior to the first diagnosis of coronary artery disease in HIV-positive individuals. Platelets 28:3, pages 301-304.
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Fuminori Kazama, Junya Nakamura, Makoto Osada, Osamu Inoue, Mitsuru Oosawa, Shogo Tamura, Nagaharu Tsukiji, Kaoru Aida, Akio Kawaguchi, Soichi Takizawa, Masahiro Kaneshige, Shoichiro Tanaka, Katsue Suzuki-inoue & Yukio Ozaki. (2015) Measurement of soluble C-type lectin-like receptor 2 in human plasma. Platelets 26:8, pages 711-719.
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Katsuki Naitoh, Yoshitaka Hosaka, Motoyasu Honda, Kumiko Ogawa, Kamon Shirakawa & Shoji Furusako. (2015) Properties of soluble glycoprotein VI, a potential platelet activation biomarker. Platelets 26:8, pages 745-750.
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G. J. Pennings, A. S. C. Yong, C. Wong, M. Al-Tamimi, E. E. Gardiner, R. K. Andrews & L. Kritharides. (2014) Circulating levels of soluble EMMPRIN (CD147) correlate with levels of soluble glycoprotein VI in human plasma. Platelets 25:8, pages 639-642.
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Thomas Wurster, Oliver Poetz, Konstantinos Stellos, Elisabeth Kremmer, Arthur Melms, Andreas Schuster, Eike Nagel, Thomas Joos, Meinrad Gawaz & Boris Bigalke. (2013) Plasma levels of soluble glycoprotein VI (sGPVI) are associated with ischemic stroke. Platelets 24:7, pages 560-565.
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Articles from other publishers (46)
Shqipdona Lahu, Kristin Adler, Katharina Mayer, Ralph Hein-Rothweiler, Isabell Bernlochner, Gjin Ndrepepa, Stefanie Schüpke, Stefan Holdenrieder, Dario Bongiovanni, Karl-Ludwig Laugwitz, Heribert Schunkert, Meinrad Gawaz, Steffen Massberg, Adnan Kastrati & Götz Münch. (2023) Plasma Soluble Glycoprotein VI, Platelet Function, Bleeding, and Ischemic Events in Patients Undergoing Elective Percutaneous Coronary Intervention. Thrombosis and Haemostasis.
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Allan Valenzuela, Miriam Ayuso, Laura Buyssens, Chloé Bars, Chris Van Ginneken, Yann Tessier & Steven Van Cruchten. (2023) Platelet Activation by Antisense Oligonucleotides (ASOs) in the Göttingen Minipig, including an Evaluation of Glycoprotein VI (GPVI) and Platelet Factor 4 (PF4) Ontogeny. Pharmaceutics 15:4, pages 1112.
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Chao Han, Pengxuan Ren, Medina Mamtimin, Linus Kruk, Edita Sarukhanyan, Chenyu Li, Hans-Joachim Anders, Thomas Dandekar, Irena Krueger, Margitta Elvers, Silvia Goebel, Kristin Adler, Götz Münch, Thomas Gudermann, Attila Braun & Elmina Mammadova-Bach. (2023) Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets. Biomedicines 11:2, pages 423.
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Azza Abdel Gawad Tantawy, Nayera Hazaa Khalil Elsherif, Fatma Soliman Ebeid, Rasha Abd El-Rahman El-Gamal, Eman Abdel Rahman Ismail, Mahmoud A. Kenny & Michael Botros Elkes morcos. (2022) Evaluation of the effect of eltrombopag therapy on the platelet collagen receptor glycoprotein VI (GPVI) expression and soluble GPVI levels in young patients with immune thrombocytopenia. Journal of Thrombosis and Thrombolysis 55:2, pages 243-251.
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Alicia Veninga, Stefan Handtke, Konstanze Aurich, Bibian M. E. Tullemans, Sanne L. N. Brouns, Silas L. Schwarz, Floor C. J. I. Heubel-Moenen, Andreas Greinacher, Johan W. M. Heemskerk, Paola E. J. van der Meijden & Thomas Thiele. (2022) GPVI expression is linked to platelet size, age, and reactivity. Blood Advances 6:14, pages 4162-4173.
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Philip Crispin, Sarah Hicks, Lucy A. Coupland, Sidra Ali & Elizabeth E. Gardiner. (2021) Cryoprecipitate as an alternative to platelet transfusion in thrombocytopenia. eJHaem 3:1, pages 80-85.
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María N. BarrachinaLidia Hermida-NogueiraLuis A. MoranVanessa CasasSarah M. Hicks, Aurelio M. SueiroYing DiRobert K. AndrewsSteve P. WatsonElizabeth E. GardinerJoaquin Abian, Montserrat Carrascal, María Pardo & Ángel García. (2020) Phosphoproteomic Analysis of Platelets in Severe Obesity Uncovers Platelet Reactivity and Signaling Pathways Alterations. Arteriosclerosis, Thrombosis, and Vascular Biology.
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Allyson M. Pishko, Robert K. AndrewsElizabeth E. Gardiner, Daniel S. Lefler & Adam Cuker. (2020) Soluble glycoprotein VI is a predictor of major bleeding in patients with suspected heparin-induced thrombocytopenia. Blood Advances 4:18, pages 4327-4332.
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Paul Vulliamy, Samantha J. Montague, Scarlett Gillespie, Melissa V. Chan, Lucy A. Coupland, Robert K. Andrews, Timothy D. Warner, Elizabeth E. Gardiner, Karim Brohi & Paul C. Armstrong. (2020) Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients. Blood Advances 4:12, pages 2623-2630.
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Samantha J. Montague, Sarah M. Hicks, Christine S‐M. Lee, Lucy A. Coupland, Christopher R. Parish, Woei M. Lee, Robert K. Andrews & Elizabeth E. Gardiner. (2020) Fibrin exposure triggers αIIbβ3‐independent platelet aggregate formation, ADAM10 activity and glycoprotein VI shedding in a charge‐dependent manner. Journal of Thrombosis and Haemostasis 18:6, pages 1447-1458.
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Yik C. Ho, Kiran D.K. Ahuja, Robert K. Andrews & Murray J. Adams. (2020) Shedding of soluble glycoprotein VI is neither affected by animal-derived antibeta-2-glycoprotein 1 antibodies nor IgG fractions from patients with systemic lupus erythematosus. Blood Coagulation & Fibrinolysis 31:4, pages 258-263.
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Jerrett K. Lau, Gabrielle J. Pennings, Caroline J. Reddel, Heather Campbell, Hai Po H. Liang, Mathew Traini, Elizabeth E. Gardiner, Andy S. Yong, Vivien M. Chen & Leonard Kritharides. (2020) Remote ischemic preconditioning inhibits platelet αIIbβ3 activation in coronary artery disease patients receiving dual antiplatelet therapy: A randomized trial. Journal of Thrombosis and Haemostasis 18:5, pages 1221-1232.
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Osamu Inoue, Makoto Osada, Junya Nakamura, Fuminori Kazama, Toshiaki Shirai, Nagaharu Tsukiji, Tomoyuki Sasaki, Hiroshi Yokomichi, Tomotaka Dohi, Makoto Kaneko, Makoto Kurano, Mitsuru Oosawa, Shogo Tamura, Kaneo Satoh, Katsuhiro Takano, Katsumi Miyauchi, Hiroyuki Daida, Yutaka Yatomi, Yukio Ozaki & Katsue Suzuki-Inoue. (2019) Soluble CLEC-2 is generated independently of ADAM10 and is increased in plasma in acute coronary syndrome: comparison with soluble GPVI. International Journal of Hematology 110:3, pages 285-294.
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Marie Lordkipanidzé, Anne-Mette Hvas & Paul Harrison. 2019. Platelets. Platelets
593
608
.
Richard Conway, Anne Madigan, Niamh Redmond, Laura Helbert, Eamonn S Molloy, Eimear Dunne, Dermot Kenny & Geraldine McCarthy. (2018) Platelet activation, as measured by plasma soluble glycoprotein VI, is not associated with disease activity or ischaemic events in giant cell arteritis. Annals of the Rheumatic Diseases 77:11, pages 1695-1697.
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Samantha J. Montague, Céline Delierneux, Christelle Lecut, Nathalie LayiosRobert J. DinsdaleChristine S.-M. Lee, Natalie S. Poulter, Robert K. AndrewsPeter HampsonChristopher M. WearnNathalie MaesJonathan Bishop, Amy Bamford, Chris Gardiner, Woei Ming LeeTariq IqbalNaiem MoiemenSteve P. Watson, Cécile Oury, Paul Harrison & Elizabeth E. Gardiner. (2018) Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI. Blood Advances 2:3, pages 240-251.
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Karl Egan, Audrey Dillon, Eimear Dunne, Barry Kevane, Zita Galvin, Patricia Maguire, Dermot Kenny, Stephen Stewart & Fionnuala Ni Ainle. (2016) Increased soluble GPVI levels in cirrhosis: evidence for early in vivo platelet activation. Journal of Thrombosis and Thrombolysis 43:1, pages 54-59.
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P. Lukito, A. Wong, J. Jing, J.F. Arthur, S.F. Marasco, D.A. Murphy, P.J. Bergin, J.A. Shaw, M. Collecutt, R.K. Andrews, E.E. Gardiner & A.K. Davis. (2016) Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI. Journal of Thrombosis and Haemostasis 14:11, pages 2253-2260.
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Adam Facey, Isaac Pinar, Jane F. Arthur, Jianlin Qiao, Jing Jing, Belden Mado, Josie Carberry, Robert K. Andrews & Elizabeth E. Gardiner. (2016) A-Disintegrin-And-Metalloproteinase (ADAM) 10 Activity on Resting and Activated Platelets. Biochemistry 55:8, pages 1187-1194.
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Jianlin Qiao, Amanda K. Davis, Marie-Christine Morel-Kopp, Christopher M. Ward, Elizabeth E. Gardiner & Robert K. Andrews. (2015) Low levels of CD9 coincidental with a novel nonsense mutation in glycoprotein Ibβ in a patient with Bernard-Soulier syndrome. Annals of Hematology 94:12, pages 2069-2071.
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Jianlin Qiao, Mohammad Al‐Tamimi, Ross I. Baker, Robert K. Andrews & Elizabeth E. Gardiner. (2015) The platelet Fc receptor, FcγRIIa. Immunological Reviews 268:1, pages 241-252.
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Janine M. Trevillyan, Jane F. Arthur, Jing Jing, Robert K. Andrews, Elizabeth E. Gardiner & Jennifer F. Hoy. (2015) Effects of abacavir administration on structural and functional markers of platelet activation. AIDS 29:17, pages 2309-2313.
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Osama M. Alshehri, Craig E. Hughes, Samantha Montague, Stephanie K. Watson, Jon Frampton, Markus Bender & Steve P. Watson. (2015) Fibrin activates GPVI in human and mouse platelets. Blood 126:13, pages 1601-1608.
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Katsuki Naitoh, Yoshitaka Hosaka, Kamon Shirakawa & Shoji Furusako. (2015) Establishment of immunoassay for platelet-derived soluble glycoprotein VI, a novel platelet marker. Journal of Immunological Methods 418, pages 52-60.
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Isabel Sánchez Guiu, Irene Martínez-Martinez, Constantino Martínez, José Navarro-Fernandez, Faustino Garcia-Candel, Francisca Ferrer-Marín, Vicente Vicente, Steve Watson, Robert Andrews, Elizabeth Gardiner, María Lozano & José Rivera. (2017) An atypical IgM class platelet cold agglutinin induces GPVI-dependent aggregation of human platelets. Thrombosis and Haemostasis 114:08, pages 313-324.
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Takumi Aota, Katsuki Naitoh, Hideo Wada, Yoshiki Yamashita, Noriki Miyamoto, Masahiro Hasegawa, Hiroki Wakabayashi, Kakunoshin Yoshida, Kunihiro Asanuma, Takeshi Matsumoto, Kohshi Ohishi, Yuji Shimokariya, Norikazu Yamada, Masakatsu Nishikawa, Naoyuki Katayama, Atsumasa Uchida & Akihiro Sudo. (2014) Elevated soluble platelet glycoprotein VI is a useful marker for DVT in postoperative patients treated with edoxaban. International Journal of Hematology 100:5, pages 450-456.
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A E-L Au, M Sashindranath, R J Borg, O Kleifeld, R K Andrews, E E Gardiner, R L Medcalf & A L Samson. (2014) Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase. Cell Death & Disease 5:9, pages e1410-e1410.
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Elizabeth E. Gardiner & Robert K. Andrews. (2014) Platelet Receptor Expression and Shedding: Glycoprotein Ib-IX-V and Glycoprotein VI. Transfusion Medicine Reviews 28:2, pages 56-60.
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Elizabeth E. Gardiner & Robert K. Andrews. (2014) Plasma sGPVI: Changing levels in human disease. Thrombosis Research 133:3, pages 306-307.
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Yoshiki Yamashita, Katsuki Naitoh, Hideo Wada, Makoto Ikejiri, Takeshi Mastumoto, Koshi Ohishi, Yoshitaka Hosaka, Masakatsu Nishikawa & Naoyuki Katayama. (2014) Elevated plasma levels of soluble platelet glycoprotein VI (GPVI) in patients with thrombotic microangiopathy. Thrombosis Research 133:3, pages 440-444.
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Mehmet Ali Kobat, Mehmet Balin, Ahmet CelikAdil Baydas & Mustafa Necati Dagli. (2023) The Relationship between Platelet Collagen Receptor Glycoprotein VI and No-Reflow Phenomenon in Patients with Acute ST-Segment Elevation Myocardial Infarction. Journal of Investigative Medicine 62:1, pages 62-70.
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Elizabeth E. Gardiner & Robert K. Andrews. 2014. A Systems Biology Approach to Blood. A Systems Biology Approach to Blood
263
275
.
Paul Harrison & Marie Lordkipanidzé. (2013) Testing Platelet Function. Hematology/Oncology Clinics of North America 27:3, pages 411-441.
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Jianlin Qiao, Simone M. Schoenwaelder, Kylie D. Mason, Huy Tran, Amanda K. Davis, Zane S. Kaplan, Shaun P. Jackson, Benjamin T. Kile, Robert K. Andrews, Andrew W. Roberts & Elizabeth E. Gardiner. (2013) Low adhesion receptor levels on circulating platelets in patients with lymphoproliferative diseases before receiving Navitoclax (ABT-263). Blood 121:8, pages 1479-1481.
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Crossref
Paul Harrison & Marie Lordkipanidzé. 2013. Platelets. Platelets
519
545
.
Marc Forestier, Mohammad Al-Tamimi, Elizabeth E. Gardiner, Corinna Hermann, Sara C. Meyer & Juerg H. Beer. (2012) Diesel exhaust particles impair platelet response to collagen and are associated with GPIbα shedding. Toxicology in Vitro 26:6, pages 930-938.
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Mohammad Al-TamimiChee Wee TanJianlin QiaoGabrielle J. PenningsAshkan JavadzadeganAndy S. C. YongJane F. ArthurAmanda K. DavisJing JingFi-Tjen MuJustin R. HamiltonShaun P. JacksonAndreas Ludwig, Michael C. Berndt, Christopher M. WardLeonard KritharidesRobert K. AndrewsElizabeth E. Gardiner. (2012) Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels. Blood 119:18, pages 4311-4320.
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Mohammad Al-Tamimi, Jane F. Arthur, Elizabeth E. Gardiner & Robert K. Andrews. (2017) Focusing on plasma glycoprotein VI. Thrombosis and Haemostasis 107:04, pages 648-655.
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Elizabeth E. Gardiner, Mohammad Al-Tamimi, Robert K. Andrews & Michael C. Berndt. 2012. Platelets and Megakaryocytes. Platelets and Megakaryocytes
321
339
.
Boris Bigalke, Oliver Pötz, Elisabeth Kremmer, Tobias Geisler, Peter Seizer, Valentina O Puntmann, Alkystis Phinikaridou, Amedeo Chiribiri, Eike Nagel, Rene M Botnar, Thomas Joos & Meinrad Gawaz. (2011) Sandwich Immunoassay for Soluble Glycoprotein VI in Patients with Symptomatic Coronary Artery Disease. Clinical Chemistry 57:6, pages 898-904.
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Crossref
Mohammad Al-TamimiGeorge GrigoriadisHuy TranEldho Paul, Patricia ServadeiMichael C. Berndt, Elizabeth E. GardinerRobert K. Andrews. (2011) Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa. Blood 117:14, pages 3912-3920.
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Mohammad Al-TamimiElizabeth E. GardinerJim Y. ThomYang ShenMatthew N. CooperGraeme J. HankeyMichael C. BerndtRoss I. BakerRobert K. Andrews. (2011) Soluble Glycoprotein VI Is Raised in the Plasma of Patients With Acute Ischemic Stroke. Stroke 42:2, pages 498-500.
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Jian L. Qiao, Yang Shen, Elizabeth E. Gardiner & Robert K. Andrews. (2010) Proteolysis of platelet receptors in humans and other species. Biological Chemistry 391:8.
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Elizabeth E. Gardiner, James Y. Thom, Mohammad Al-Tamimi, Annette Hughes, Michael C. Berndt, Robert K. Andrews & Ross I. Baker. (2010) Restored platelet function after romiplostim treatment in a patient with immune thrombocytopenic purpura. British Journal of Haematology 149:4, pages 625-628.
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Boris Bigalke, Konstantinos Stellos, Tobias Geisler, Stephan Lindemann, Andreas E. May & Meinrad Gawaz. (2010) Glycoprotein VI as a prognostic biomarker for cardiovascular death in patients with symptomatic coronary artery disease. Clinical Research in Cardiology 99:4, pages 227-233.
Crossref
Crossref
Youtao Zhang, Yiming Zhao, Shiqi Lu, Mingqing Zhu, Yang He & Changgeng Ruan. (2010) A High-Throughput Biotin-Avidin-ELISA for Studying Expression of Platelet Membrane Glycoproteins and Its Clinical Application. The Tohoku Journal of Experimental Medicine 222:1, pages 83-88.
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