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International Journal of Radiation Biology Volume 96, 2020 - Issue 1: Non-clinical Radiation Biology and Pharmacology Models: Appraisal of State-of-the-Art and Innovation
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Countermeasures

Modeling radiation-induced lung injury: lessons learned from whole thorax irradiation

Tyler A. BeachDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA; ORCID Iconhttp://orcid.org/0000-0002-3859-9288View further author information
ORCID Icon,
Angela M. GrovesDepartment of Pediatrics and Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; View further author information
,
Jacqueline P. WilliamsDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA; ;Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY, USAORCID Iconhttp://orcid.org/0000-0002-5635-1526View further author information
ORCID Icon &
Jacob N. FinkelsteinDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, USA; ;Department of Pediatrics and Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA; Correspondence[email protected]
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Pages 129-144 | Received 26 Jul 2018, Accepted 13 Sep 2018, Published online: 25 Oct 2018

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Chrysi Keskinidou, Alice G Vassiliou, Ioanna Dimopoulou, Anastasia Kotanidou & Stylianos E Orfanos. (2022) Mechanistic Understanding of Lung Inflammation: Recent Advances and Emerging Techniques. Journal of Inflammation Research 15, pages 3501-3546.
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Matthew D. Fountain, Laura A. McLellan, Natalie L. Smith, Brian F. Loughery, Joseph T. Rakowski, Harley Y. Tse & Gilda G. Hillman. (2020) Isoflavone-mediated radioprotection involves regulation of early endothelial cell death and inflammatory signaling in Radiation-Induced lung injury. International Journal of Radiation Biology 96:2, pages 245-256.
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Simon Authier, David Cassatt & Polly Chang. (2020) Non-clinical radiation biology and pharmacology models: appraisal of state-of-the-art and innovation. International Journal of Radiation Biology 96:1, pages 1-3.
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Haochun Guo, Jiajia Chen, Hanxu Yu, Lei Dong, Ran Yu, Qingju Li, Jian Song, Haoyu Chen, Haijun Zhang, Juan Pu & Wanpeng Wang. (2023) Activation of Nrf2/ARE pathway by Anisodamine (654-2) for Inhibition of cellular aging and alleviation of Radiation-Induced lung injury. International Immunopharmacology 124, pages 110864.
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Queeny Dasgupta, Amanda Jiang, Amy M. Wen, Robert J. Mannix, Yuncheng Man, Sean Hall, Emilia Javorsky & Donald E. Ingber. (2023) A human lung alveolus-on-a-chip model of acute radiation-induced lung injury. Nature Communications 14:1.
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Rama Malaviya, Jeffrey D. Laskin, Rita Businaro & Debra L. Laskin. (2023) Targeting Tumor Necrosis Factor Alpha to Mitigate Lung Injury Induced by Mustard Vesicants and Radiation. Disaster Medicine and Public Health Preparedness 17.
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Yidan Su, Hengqing Cui, Chao Yang, Lu Li, Fei Xu, Jie Gao & Wenjun Zhang. (2022) Hydrogels for the treatment of radiation-induced skin and mucosa damages: An up-to-date overview. Frontiers in Materials 9.
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Miaomiao Yang, Qiang Fan, Tom K. Hei, Guodong Chen, Wei Cao, Gang Meng & Wei Han. (2022) Single-Cell Transcriptome Analysis of Radiation Pneumonitis Mice. Antioxidants 11:8, pages 1457.
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Alexander N. GarciaNancy G. Casanova, Carrie L. Kempf, Tadeo Bermudez, Daniel G. Valera, Jin H. Song, Xiaoguang Sun, Hua CaiLiliana Moreno-Vinasco, Taylor Gregory, Radu C. Oita, Vivian Reyes Hernon, Sara M. Camp, Claude Rogers, Espoir M. Kyubwa, Naresh Menon, James Axtelle, Jay Rappaport, Christian Bime, Saad Sammani, Anne E. Cress & Joe G. N. Garcia. (2022) eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis. American Journal of Respiratory Cell and Molecular Biology 66:5, pages 497-509.
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Shiying Niu, Yuehua Zhang, Changsheng Cong, Zhicheng Wu, Zhaopeng Wang, Meili Sun, Chengfang Yao & Yueying Zhang. (2022) Comparative Study of Radiation-induced Lung Injury Model in Two Strains of Mice. Health Physics 122:5, pages 579-585.
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Guru Prasad Sharma, Brian L. Fish, Anne C. Frei, Jayashree Narayanan, Tracy Gasperetti, Dana Scholler, Lauren Pierce, Nathan Szalewski, Noah Blue, Meetha Medhora & Heather A. Himburg. (2022) Pharmacologic ACE-Inhibition Mitigates Radiation-Induced Pneumonitis by Suppressing ACE-Expressing Lung Myeloid Cells. International Journal of Radiation Oncology*Biology*Physics 113:1, pages 177-191.
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Yan Ding, Lei Ma, Limin He, Quanxiao Xu, Zhuang Zhang, Zhen Zhang, Xinping Zhang, Rui Fan, Wenjun Ma, Ya’nan Sun, Baile Zhang, Wentai Li, Yao Zhai & Jiandong Zhang. (2022) A strategy for attenuation of acute radiation-induced lung injury using crocetin from gardenia fruit. Biomedicine & Pharmacotherapy 149, pages 112899.
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Anna A. Friedl, Kevin M. Prise, Karl T. Butterworth, Pierre Montay‐Gruel & Vincent Favaudon. (2021) Radiobiology of the FLASH effect. Medical Physics 49:3, pages 1993-2013.
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Alexander N. Garcia, Nancy G. Casanova, Daniel G. Valera, Xiaoguang Sun, Jin H. Song, Carrie L. Kempf, Liliana Moreno-Vinasco, Kimberlie Burns, Tadeo Bermudez, Mia Valdez, Genesis Cuellar, Taylor Gregory, Radu C. Oita, Vivian Reyes Hernon, Christy Barber, Sara M. Camp, Diego Martin, Zhonglin Liu, Christian Bime, Saad Sammani, Anne E. Cress & Joe GN Garcia. (2022) Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization. Translational Research 239, pages 44-57.
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Annaïg Bertho, Morgane Dos Santos, Sarah Braga-Cohen, Valérie Buard, Vincent Paget, Olivier Guipaud, Georges Tarlet, Fabien Milliat & Agnès François. (2021) Preclinical Model of Stereotactic Ablative Lung Irradiation Using Arc Delivery in the Mouse: Is Fractionation Worthwhile?. Frontiers in Medicine 8.
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Ognoon Mungunsukh, Jeffy George, Elizabeth A McCart, Andrew L Snow, Joseph J Mattapallil, Steven R Mog, Ronald Allan M Panganiban, David L Bolduc, W Bradley Rittase, Roxane M Bouten & Regina M Day. (2021) Captopril reduces lung inflammation and accelerated senescence in response to thoracic radiation in mice. Journal of Radiation Research 62:2, pages 236-248.
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A. Bertho, M. Dos Santos, A. François & F. Milliat. (2020) Radiobiologie des très fortes doses par fraction : connaissances en 2020 et nouvelles modélisations précliniques. Radioprotection 56:1, pages 11-24.
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Rama Malaviya, Howard M. Kipen, Rita Businaro, Jeffrey D. Laskin & Debra L. Laskin. (2020) Pulmonary toxicants and fibrosis: innate and adaptive immune mechanisms. Toxicology and Applied Pharmacology 409, pages 115272.
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Lu-Kai Wang, Tsai-Jung Wu, Ji-Hong Hong, Fang-Hsin Chen, John Yu, Chun-Chieh Wang & Andrea Ballini. (2020) Radiation Induces Pulmonary Fibrosis by Promoting the Fibrogenic Differentiation of Alveolar Stem Cells. Stem Cells International 2020, pages 1-12.
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Long Li, Xiaoqi Nie, Minxiao Yi, Wan Qin, Fang Li, Bili Wu & Xianglin Yuan. (2020) Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis. Frontiers in Oncology 10.
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Annaïg Bertho, Morgane Dos Santos, Valérie Buard, Vincent Paget, Olivier Guipaud, Georges Tarlet, Fabien Milliat & Agnès François. (2020) Preclinical Model of Stereotactic Ablative Lung Irradiation Using Arc Delivery in the Mouse: Effect of Beam Size Changes and Dose Effect at Constant Collimation. International Journal of Radiation Oncology*Biology*Physics 107:3, pages 548-562.
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Jian Jian Li. (2020) Mitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by Radiotherapy. iScience 23:6, pages 101215.
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Frédéric Soysouvanh, Mohamed Amine Benadjaoud, Morgane Dos Santos, Michele Mondini, Jérémy Lavigne, Annaïg Bertho, Valérie Buard, Georges Tarlet, Serge Adnot, Eric Deutsch, Olivier Guipaud, Vincent Paget, Agnès François & Fabien Milliat. (2020) Stereotactic Lung Irradiation in Mice Promotes Long-Term Senescence and Lung Injury. International Journal of Radiation Oncology*Biology*Physics 106:5, pages 1017-1027.
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