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Original Article

Heat-induced Intranuclear Protein Aggregation and Thermal Radiosensitization

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Pages 203-209 | Received 25 May 1994, Accepted 19 Sep 1994, Published online: 03 Jul 2009

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Berina Eppink, Przemek M. Krawczyk, Jan Stap & Roland Kanaar. (2012) Hyperthermia-induced DNA repair deficiency suggests novel therapeutic anti-cancer strategies. International Journal of Hyperthermia 28:6, pages 509-517.
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Vladimir L. Gabai, Julia A. Yaglom, Todd Waldman & Michael Y. Sherman. (2009) Heat Shock Protein Hsp72 Controls Oncogene-Induced Senescence Pathways in Cancer Cells. Molecular and Cellular Biology 29:2, pages 559-569.
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Andrei Laszlo, Teri Davidson, Amanda Harvey, Julia E. Sim, Robert S. Malyapa, Douglas R. Spitz & Joseph L. Roti Roti. (2006) Alterations in heat-induced radiosensitization accompanied by nuclear structure alterations in Chinese hamster cells. International Journal of Hyperthermia 22:1, pages 43-60.
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J. R. Dynlacht, M. Xu, R. K. Pandita, E. A. Wetzel & J. L. Roti Roti. (2004) Effects of heat shock on the Mre11/Rad50/Nbs1 complex in irradiated or unirradiated cells. International Journal of Hyperthermia 20:2, pages 144-156.
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R.S.L. Wong, J.R. Dynlacht, B. Cedervall & W.C. Dewey. (1995) Analysis by Pulsed-field Gel Electrophoresis of DNA Double-strand Breaks Induced by Heat and/or X-irradiation in Bulk and Replicating DNA of CHO Cells. International Journal of Radiation Biology 68:2, pages 141-152.
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Enzo M. Scutigliani, Yongxin Liang, Marloes IJff, Hans Rodermond, Xionge Mei, Miriam P. Korver, Vaneesha S. Orie, Ron A. Hoebe, Daisy I. Picavet, Arlene Oei, Roland Kanaar & Przemek M. Krawczyk. (2022) Evaluation of the Heat Shock Protein 90 Inhibitor Ganetespib as a Sensitizer to Hyperthermia-Based Cancer Treatments. Cancers 14:21, pages 5250.
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Mark W. Dewhirst, James R. Oleson, John Kirkpatrick & Timothy W. Secomb. (2022) Accurate Three-Dimensional Thermal Dosimetry and Assessment of Physiologic Response Are Essential for Optimizing Thermoradiotherapy. Cancers 14:7, pages 1701.
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Ajoy Basak & Sarmistha Basak. (2022) Protein Aggregation and Self Assembly in Health and Disease. Current Proteomics 19:1, pages 4-19.
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Ramakrishna R. Voggu, Ravali Alagandula, Xiang Zhou, Bin Su, Bo Zhong & Baochuan Guo. (2015) A rapid LC-MS/MS method for quantification of CSUOH0901, a novel antitumor agent, in rat plasma. Biomedical Chromatography 29:5, pages 797-802.
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Ekaterina Y. Lukianova-Hleb, Alexander O. Oginsky, John S. Olson & Dmitri O. Lapotko. (2011) Short laser pulse-induced irreversible photothermal effects in red blood cells. Lasers in Surgery and Medicine 43:3, pages 249-260.
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Joseph L. Roti Roti, Robert P. VanderWaal & Andrei Laszlo. 2011. Molecular Determinants of Radiation Response. Molecular Determinants of Radiation Response 227 249 .
Bogdan I. Gerashchenko, Gerirose Gooding & Joseph R. Dynlacht. (2010) Hyperthermia alters the interaction of proteins of the Mre11 complex in irradiated cells. Cytometry Part A 77A:10, pages 940-952.
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SATOKO ADACHI, SATOSHI KOKURA & TOSHIKAZU YOSHIKAWA. (2010) Effect of Heating Prior to Gemcitabine Exposure on Therapeutic Outcomes in Combination Therapies. Thermal Medicine 26:3, pages 75-85.
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Penny K. Sneed, Paul R. Stauffer, Gloria C. Li, Xiaorong Sun & Robert J. Myerson. 2010. Leibel and Phillips Textbook of Radiation Oncology. Leibel and Phillips Textbook of Radiation Oncology 1564 1593 .
Marianne Barrier, David J. Dix & Philip E. Mirkes. (2009) Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice. Birth Defects Research Part A: Clinical and Molecular Teratology 85:8, pages 732-740.
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Peng SHI, Ming-ming WANG, Li-yu JIANG, Huan-tao LIU & Jing-zhong SUN. (2008) Paclitaxel-doxorubicin sequence is more effective in breast cancer cells with heat shock protein 27 overexpression. Chinese Medical Journal 121:20, pages 1975-1979.
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Konjeti R. Sekhar, Vijayakumar N. Sonar, Venkatraj Muthusamy, Soumya Sasi, Andrei Laszlo, Jamil Sawani, Nobuo Horikoshi, Ryuji Higashikubo, Robert G. Bristow, Michael J. Borrelli, Peter A. Crooks, James R. Lepock, Joseph L. Roti Roti & Michael L. Freeman. (2007) Novel Chemical Enhancers of Heat Shock Increase Thermal Radiosensitization through a Mitotic Catastrophe Pathway. Cancer Research 67:2, pages 695-701.
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H.H. Kampinga. 2006. Molecular Chaperones in Health and Disease. Molecular Chaperones in Health and Disease 1 42 .
Y. Tanaka, K. Fujiwara, H. Tanaka, K. Maehata & I. Kohno. (2004) Paclitaxel inhibits expression of heat shock protein 27 in ovarian and uterine cancer cells. International Journal of Gynecological Cancer 14:4, pages 616-620.
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Wei-Guo Zhu, Joshua D. Seno, Brian D. Beck & Joseph R. Dynlacht. (2001) Translocation of MRE11 from the Nucleus to the Cytoplasm as a Mechanism of Radiosensitization by Heat 1 . Radiation Research 156:1, pages 95-102.
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James R. Lepock, Harold E. Frey, Miriam L. Heynen, Guillermo A. Senisterra & Raymond L. Warters. (2001) The nuclear matrix is a thermolabile cellular structure. Cell Stress & Chaperones 6:2, pages 136.
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Martin E. FederGretchen E. Hofmann. (1999) HEAT-SHOCK PROTEINS, MOLECULAR CHAPERONES, AND THE STRESS RESPONSE: Evolutionary and Ecological Physiology. Annual Review of Physiology 61:1, pages 243-282.
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R. C. Rietbroek, P. J. M. van de Vaart, J. Haveman, F. A. Blommaert, A. Geerdink, P. J. M. Bakker & C. H. N. Veenhof. (1997) Hyperthermia enhances the cytotoxicity and platinum-DNA adduct formation of lobaplatin and oxaliplatin in cultured SW 1573 cells. Journal of Cancer Research and Clinical Oncology 123:1, pages 6-12.
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