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The pharmacokinetics of flavanones

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Hui Teng, Yimei Zheng, Hui Cao, Qun Huang, Jianbo Xiao & Lei Chen. (2023) Enhancement of bioavailability and bioactivity of diet-derived flavonoids by application of nanotechnology: a review. Critical Reviews in Food Science and Nutrition 63:3, pages 378-393.
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Dan Yuan, Yujie Guo, Feiyan Pu, Can Yang, Xuecheng Xiao, Hongzhi Du, Jianhua He & Shan Lu. (2024) Opportunities and challenges in enhancing the bioavailability and bioactivity of dietary flavonoids: A novel delivery system perspective. Food Chemistry 430, pages 137115.
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Rishi Richa, Deepika Kohli, Dinesh Vishwakarma, Ananya Mishra, Bhumika Kabdal, Anjineyulu Kothakota, Shruti Richa, Ranjna Sirohi, Rohitashw Kumar & Bindu Naik. (2023) Citrus fruit: Classification, value addition, nutritional and medicinal values, and relation with pandemic and hidden hunger. Journal of Agriculture and Food Research 14, pages 100718.
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Homa Fatma & Hifzur R Siddique. (2023) Research and Patents Status of Selected Phytochemicals Against Cancer: How Close and How Far?. Recent Patents on Anti-Cancer Drug Discovery 18:4, pages 428-447.
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VS Shilpa, Rafeeya Shams, Kshirod Kumar Dash, Vinay Kumar Pandey, Aamir Hussain Dar, Shaikh Ayaz Mukarram, Endre Harsányi & Béla Kovács. (2023) Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin: A Review. Molecules 28:15, pages 5623.
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Shen Chen, Xiaojing Wang, Yu Cheng, Hongsheng Gao & Xuehao Chen. (2023) A Review of Classification, Biosynthesis, Biological Activities and Potential Applications of Flavonoids. Molecules 28:13, pages 4982.
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Wei-Bing Zhuang, Yu-Hang Li, Xiao-Chun Shu, Yu-Ting Pu, Xiao-Jing Wang, Tao Wang & Zhong Wang. (2023) The Classification, Molecular Structure and Biological Biosynthesis of Flavonoids, and Their Roles in Biotic and Abiotic Stresses. Molecules 28:8, pages 3599.
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Isabela Sandy Rosa, Laura Oliveira Pires & Juliane Karine Ishida. 2023. Plants as Bioreactors for Industrial Molecules. Plants as Bioreactors for Industrial Molecules 367 391 .
Anns Mahboob, Degiri Kalana Lasanga Senevirathne, Pradipta Paul, Faisal Nabi, Rizwan Hasan Khan & Ali Chaari. (2023) An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes. International Journal of Biological Macromolecules 225, pages 318-350.
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Rizliya Visvanathan & Gary Williamson. (2022) Review of factors affecting citrus polyphenol bioavailability and their importance in designing in vitro, animal, and intervention studies. Comprehensive Reviews in Food Science and Food Safety 21:6, pages 4509-4545.
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Hengli Zhao, Gaopeng Xian, Jingxin Zeng, Guoheng Zhong, Dongqi An, You Peng, Dongtu Hu, Yingwen Lin, Juncong Li, Shuwen Su, Yunshan Ning, Dingli Xu & Qingchun Zeng. (2022) Hesperetin, a Promising Dietary Supplement for Preventing the Development of Calcific Aortic Valve Disease. Antioxidants 11:11, pages 2093.
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Shuning Ding, Peipei Wang, Xi Pang, Leyin Zhang, Lihui Qian, Xinru Jia, Wenqian Chen, Shanming Ruan & Leitao Sun. (2022) The new exploration of pure total flavonoids extracted from Citrus maxima (Burm.) Merr. as a new therapeutic agent to bring health benefits for people. Frontiers in Nutrition 9.
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Sara Julietta Lozano-Herrera, Gabriel Luna-Bárcenas, Ramón Gerardo Guevara-González, Rocio Campos-Vega, Juan Carlos Solís-Sáinz, Ana Gabriela Hernández-Puga & Haydé Azeneth Vergara-Castañeda. (2022) Fermentation Extract of Naringenin Increases the Expression of Estrogenic Receptor β and Modulates Genes Related to the p53 Signalling Pathway, miR-200c and miR-141 in Human Colon Cancer Cells Exposed to BPA. Molecules 27:19, pages 6588.
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Hao Yang, Yujie Wang, Shan Xu, Jie Ren, Lidan Tang, Jinhong Gong, Ying Lin, Hufeng Fang & Dan Su. (2022) Hesperetin, a Promising Treatment Option for Diabetes and Related Complications: A Literature Review. Journal of Agricultural and Food Chemistry 70:28, pages 8582-8592.
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Yang Yang, Myah Trevethan, Shu Wang & Ling Zhao. (2022) Beneficial effects of citrus flavanones naringin and naringenin and their food sources on lipid metabolism: An update on bioavailability, pharmacokinetics, and mechanisms. The Journal of Nutritional Biochemistry 104, pages 108967.
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Valeria Rodríguez, María Rivoira, Gabriela Picotto, Gabriela Díaz de Barboza, Alejandro Collin & Nori Tolosa de Talamoni. (2022) Analysis of the Molecular Mechanisms by Flavonoids with Potential Use for Osteoporosis Prevention or Therapy. Current Medicinal Chemistry 29:16, pages 2913-2936.
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Danila Cianciosi, Tamara Y. Forbes-Hernández, Lucia Regolo, José M. Alvarez-Suarez, Maria Dolores Navarro-Hortal, Jianbo Xiao, José L. Quiles, Maurizio Battino & Francesca Giampieri. (2022) The reciprocal interaction between polyphenols and other dietary compounds: Impact on bioavailability, antioxidant capacity and other physico-chemical and nutritional parameters. Food Chemistry 375, pages 131904.
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Přemysl Mladěnka. (2022) Special Issue “Dietary (Poly)Phenols and Health”. Nutrients 14:7, pages 1402.
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Ke Zhao, Mei Yao, Xin Zhang, Feng Xu, Xingfeng Shao, Yingying Wei & Hongfei Wang. (2021) Flavonoids and intestinal microbes interact to alleviate depression. Journal of the Science of Food and Agriculture 102:4, pages 1311-1318.
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Xuan Zeng, Yuying Zheng, Yan He, Wei Peng & Weiwei Su. (2022) A Rapid LC-MS/MS Method for Simultaneous Determination of Ten Flavonoid Metabolites of Naringin in Rat Urine and Its Application to an Excretion Study. Foods 11:3, pages 316.
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Pascual García-Pérez & Pedro P. Gallego. 2022. Lipid Oxidation in Food and Biological Systems. Lipid Oxidation in Food and Biological Systems 405 426 .
Catarina Bessa-Pereira, Ricardo Dias, Elsa Brandão, Nuno Mateus, Victor de Freitas, Susana Soares & Rosa Pérez-Gregorio. 2021. Functional Foods - Phytochemicals and Health Promoting Potential. Functional Foods - Phytochemicals and Health Promoting Potential.
Rizliya Visvanathan & Gary Williamson. (2021) Effect of citrus fruit and juice consumption on risk of developing type 2 diabetes: Evidence on polyphenols from epidemiological and intervention studies. Trends in Food Science & Technology 115, pages 133-146.
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Raghad Khalid AL-Ishaq, Alena Liskova, Peter Kubatka & Dietrich Büsselberg. (2021) Enzymatic Metabolism of Flavonoids by Gut Microbiota and Its Impact on Gastrointestinal Cancer. Cancers 13:16, pages 3934.
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Iara L. de Matos, Willian G. Birolli, Darlisson de A. Santos, Marcia Nitschke & André Luiz M. Porto. (2021) Stereoselective reduction of flavanones by marine-derived fungi. Molecular Catalysis 513, pages 111734.
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Simona Saponara, Fabio Fusi, Daniele Iovinelli, Amer Ahmed, Alfonso Trezza, Ottavia Spiga, Giampietro Sgaragli & Massimo Valoti. (2021) Flavonoids and hERG channels: Friends or foes?. European Journal of Pharmacology 899, pages 174030.
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Donatella Verbanac, Andrea Čeri, Iva Hlapčić, Mehdi Shakibaei, Aranka Brockmueller, Božo Krušlin, Neven Ljubičić, Neven Baršić, Dijana Detel, Lara Batičić, Lada Rumora, Anita Somborac-Bačura, Mario Štefanović, Ivana Ćelap, Alma Demirović, Roberta Petlevski, József Petrik, Marija Grdić Rajković, Andrea Hulina-Tomašković, Ivana Rako, Luciano Saso & Karmela Barišić. (2021) Profiling Colorectal Cancer in the Landscape Personalized Testing—Advantages of Liquid Biopsy. International Journal of Molecular Sciences 22:9, pages 4327.
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Qi Tang, Ruiying Zhang, Jiali Zhou, Kanghong Zhao, Ying Lu, Yajie Zheng, Changqiao Wu, Feng Chen, Detian Mu, Zixuan Ding, Hongqi Xie & Yingjie He. (2020) The levels of bioactive ingredients in Citrus aurantium L. at different harvest periods and antioxidant effects on H 2 O 2 ‐induced RIN‐m5F cells . Journal of the Science of Food and Agriculture 101:4, pages 1479-1490.
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María Ángeles Ávila-Gálvez, Juan Antonio Giménez-Bastida, Antonio González-Sarrías & Juan Carlos Espín. (2021) New Insights into the Metabolism of the Flavanones Eriocitrin and Hesperidin: A Comparative Human Pharmacokinetic Study. Antioxidants 10:3, pages 435.
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Mohammed Bhia, Mahzad Motallebi, Banafshe Abadi, Atefeh Zarepour, Miguel Pereira-Silva, Farinaz Saremnejad, Ana Cláudia Santos, Ali Zarrabi, Ana Melero, Seid Mahdi Jafari & Mehdi Shakibaei. (2021) Naringenin Nano-Delivery Systems and Their Therapeutic Applications. Pharmaceutics 13:2, pages 291.
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Matthew G. Pontifex, Mohammad M. A. H. Malik, Emily Connell, Michael Müller & David Vauzour. (2021) Citrus Polyphenols in Brain Health and Disease: Current Perspectives. Frontiers in Neuroscience 15.
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Alessandra Nishioka, Eric de Castro Tobaruela, Layanne Nascimento Fraga, Francisco A. Tomás-Barberán, Franco Maria Lajolo & Neuza Mariko Aymoto Hassimotto. (2021) Stratification of Volunteers According to Flavanone Metabolite Excretion and Phase II Metabolism Profile after Single Doses of ‘Pera’ Orange and ‘Moro’ Blood Orange Juices. Nutrients 13:2, pages 473.
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Fanye Liu, Shuhua Pei, Wenqi Li, Xiao Wang, Chao Liang, Ruohan Yang, Zhansheng Zhang, Xin Yao, Dong Fang, Songqiang Xie & Hua Sun. (2021) Characterization of Formononetin Sulfonation in SULT1A3 Overexpressing HKE293 Cells: Involvement of Multidrug Resistance-Associated Protein 4 in Excretion of Sulfate. Frontiers in Pharmacology 11.
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Jiebiao Chen, Yue Wang, Tailin Zhu, Sijia Yang, Jinping Cao, Xian Li, Li-Shu Wang & Chongde Sun. (2020) Beneficial Regulatory Effects of Polymethoxyflavone—Rich Fraction from Ougan (Citrus reticulata cv. Suavissima) Fruit on Gut Microbiota and Identification of Its Intestinal Metabolites in Mice. Antioxidants 9:9, pages 831.
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Paolo Bellavite & Alberto Donzelli. (2020) Hesperidin and SARS-CoV-2: New Light on the Healthy Function of Citrus Fruits. Antioxidants 9:8, pages 742.
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Ying‐Jie He, Meng Zhu, Ying Zhou, Kang‐Hong Zhao, Jia‐Li Zhou, Zi‐Heng Qi, Yan‐Yan Zhu, Zhao‐Jie Wang, Tian‐Zhen Xie, Qi Tang, Yi‐Fen Wang & Xiao‐Dong Luo. (2020) Comparative investigation of phytochemicals among ten citrus herbs by ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time‐of‐flight mass spectrometry and evaluation of their antioxidant properties. Journal of Separation Science 43:16, pages 3349-3358.
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Assylzhan Yessenkyzy, Timur Saliev, Marina Zhanaliyeva, Abdul-Razak Masoud, Bauyrzhan Umbayev, Shynggys Sergazy, Elena Krivykh, Alexander Gulyayev & Talgat Nurgozhin. (2020) Polyphenols as Caloric-Restriction Mimetics and Autophagy Inducers in Aging Research. Nutrients 12:5, pages 1344.
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Gzona Bajraktari & Johanna Weiss. (2020) The aglycone diosmetin has the higher perpetrator drug-drug interaction potential compared to the parent flavone diosmin. Journal of Functional Foods 67, pages 103842.
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Cristina Zaragozá, Lucinda Villaescusa, Jorge Monserrat, Francisco Zaragozá & Melchor Álvarez-Mon. (2020) Potential Therapeutic Anti-Inflammatory and Immunomodulatory Effects of Dihydroflavones, Flavones, and Flavonols. Molecules 25:4, pages 1017.
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Monika Stompor. (2020) A Review on Sources and Pharmacological Aspects of Sakuranetin. Nutrients 12:2, pages 513.
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