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A systematic review of synthetic tyrosinase inhibitors and their structure-activity relationship

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Patrycja Ledwoń, Waldemar Goldeman, Katarzyna Hałdys, Michał Jewgiński, Greta Calamai, Joanna Rossowska, Anna Maria Papini, Paolo Rovero & Rafał Latajka. (2023) Tripeptides conjugated with thiosemicarbazones: new inhibitors of tyrosinase for cosmeceutical use. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Najla A. Alshaye, Ehsan Ullah Mughal, Eslam B. Elkaeed, Zaman Ashraf, Sana Kehili, Yasir Nazir, Nafeesa Naeem, Nida Abdul Majeed & Amina Sadiq. (2023) Synthesis and biological evaluation of substituted aurone derivatives as potential tyrosinase inhibitors: in vitro, kinetic, QSAR, docking and drug-likeness studies. Journal of Biomolecular Structure and Dynamics 41:17, pages 8307-8322.
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Zhiyun Peng, Guangcheng Wang, Jing Jing Wang & Yong Zhao. (2023) Anti-browning and antibacterial dual functions of novel hydroxypyranone-thiosemicarbazone derivatives as shrimp preservative agents: Synthesis, bio-evaluation, mechanism, and application. Food Chemistry 419, pages 136106.
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Jia Song, Jiaying Yu, Kai Sun, Zhixin Chen, Xiaoxiao Xing, Yumeng Yang, Chunyu Sun & Zhifei Wang. (2023) A high quantum yield xanthene-based fluorescent probe for the specific detection of tyrosinase and cell imaging. Journal of Photochemistry and Photobiology A: Chemistry 441, pages 114693.
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Narges Hosseini Nasab, Hussain Raza, Young Seok Eom, Mubashir Hassan, Andrzej Kloczkowski & Song Ja Kim. (2023) Synthesis and discovery of potential tyrosinase inhibitor of new coumarin‐based thiophenyl‐pyrazolylthiazole nuclei: In vitro evaluation, cytotoxicity, kinetic, and computational studies. Chemical Biology & Drug Design 101:6, pages 1262-1272.
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Guangcheng Wang, Min He, Yong Huang & Zhiyun Peng. (2023) Synthesis and biological evaluation of new kojic acid-1,3,4-oxadiazole hybrids as tyrosinase inhibitors and their application in the anti-browning of fresh-cut mushrooms. Food Chemistry 409, pages 135275.
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Nguyen Manh Khoa, Nguyen Viet Phong, Seo Young Yang, Byung Sun Min & Jeong Ah Kim. (2023) Spectroscopic analysis, kinetic mechanism, computational docking, and molecular dynamics of active metabolites from the aerial parts of Astragalus membranaceusBunge as tyrosinase inhibitors. Bioorganic Chemistry 134, pages 106464.
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Qi Dai, Zichun Qi, Zhenzhen Yan, Biao Yu, Jingqiu Li, Baosheng Ge, Hua He, Fang Huang & Xiaojuan Wang. (2023) A Blue/NIR ratiometric fluorescent probe for intracellular detection of Tyrosinase and the inhibitor screening. Talanta 254, pages 124175.
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Zhiyun Peng, Guangcheng Wang, Yan He, Jing Jing Wang & Yong Zhao. (2023) Tyrosinase inhibitory mechanism and anti-browning properties of novel kojic acid derivatives bearing aromatic aldehyde moiety. Current Research in Food Science 6, pages 100421.
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M. Carcelli, C. Compari, E. Fisicaro, M. Incerti, F. Miglioli, E. Peracchia, T. A. Pertinhez, D. Rogolino, N. Ronda, S. Gentili & M. Tegoni. (2022) A potentiometric and spectrofluorimetric approach to unravel inhibitory effects of semi- and thiosemicarbazones on mushroom tyrosinase activity. JBIC Journal of Biological Inorganic Chemistry 28:1, pages 17-27.
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Jing Zhang, Jing Lei, Zhengkun Liu, Zhenyu Chu & Wanqin Jin. (2022) Nanomaterial-based electrochemical enzymatic biosensors for recognizing phenolic compounds in aqueous effluents. Environmental Research 214, pages 113858.
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Wenjun Xue, Xuan Liu, Wenzhu Zhao & Zhipeng Yu. (2022) Identification and molecular mechanism of novel tyrosinase inhibitory peptides from collagen. Journal of Food Science 87:6, pages 2744-2756.
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Pablo Garcia-Molina, Francisco Garcia-Molina, Jose Antonio Teruel-Puche, Jose Neptuno Rodriguez-Lopez, Francisco Garcia-Canovas & Jose Luis Muñoz-Muñoz. (2022) The Relationship between the IC50 Values and the Apparent Inhibition Constant in the Study of Inhibitors of Tyrosinase Diphenolase Activity Helps Confirm the Mechanism of Inhibition. Molecules 27:10, pages 3141.
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Ludmila Martínková, Barbora Křístková & Vladimír Křen. (2022) Laccases and Tyrosinases in Organic Synthesis. International Journal of Molecular Sciences 23:7, pages 3462.
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Liling Wang, Yuchuan Qin, Yanbin Wang, Bentong Liu & Yifeng Zhou. (2021) A pair of homoisoflavonoid analogues (6-aldehydo-isoophiopogonanone A/6-aldehydo-isoophiopogonanone B) from Ophiopogon japonicus as a tyrosinase inhibitor: inhibitory activity, conformational change and mechanism. European Food Research and Technology 248:2, pages 553-565.
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Zeynep Molo, Gülsen Tel-Çayan, Ebru Deveci, Mehmet Öztürk & Mehmet Emin Duru. (2021) Insight into isolation and characterization of compounds of Chaerophyllum bulbosum aerial part with antioxidant, anticholinesterase, anti-urease, anti-tyrosinase, and anti-diabetic activities. Food Bioscience 42, pages 101201.
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