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Research Article

Ochratoxin A: The Continuing Enigma

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Pages 33-60 | Published online: 10 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (31)

Xianjiang Li, Wen Ma, Zhiyong Ma, Qinghe Zhang & Hongmei Li. (2022) Recent progress in determination of ochratoxin a in foods by chromatographic and mass spectrometry methods. Critical Reviews in Food Science and Nutrition 62:20, pages 5444-5461.
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Muhammad A. Tahir, Asghar Abbas, Muhammad Muneeb, Rana M. Bilal, Kashif Hussain, Abdel-Moneim E. Abdel-Moneim, Mayada R. Farag, Kuldeep Dhama, Shaaban S. Elnesr & Mahmoud Alagawany. (2022) Ochratoxicosis in poultry: occurrence, environmental factors, pathological alterations and amelioration strategies. World's Poultry Science Journal 78:3, pages 727-749.
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Sheraz Ahmed Bhatti, Muhammad Zargham Khan, Muhammad Kashif Saleemi, Zahoor Ul Hassan & Ahrar Khan. (2022) Ameliorative role of dietary activated carbon against ochratoxin-A induced oxidative damage, suppressed performance and toxicological effects. Toxin Reviews 41:1, pages 108-118.
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Sahar Fanoudi, Mohaddeseh Sadat Alavi, Gholamreza Karimi & Hossein Hosseinzadeh. (2020) Milk thistle (Silybum Marianum) as an antidote or a protective agent against natural or chemical toxicities: a review. Drug and Chemical Toxicology 43:3, pages 240-254.
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Luca Campone, Anna Lisa Piccinelli, Rita Celano, Imma Pagano, Rosa Di Sanzo, Sonia Carabetta, Mariateresa Russo & Luca Rastrelli. (2018) Occurrence of aflatoxin M1 in milk samples from Italy analysed by online-SPE UHPLC-MS/MS. Natural Product Research 32:15, pages 1803-1808.
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Aisha Khatoon, Muhammad Zargham Khan, Zain ul Abidin & Sheraz Ahmed Bhatti. (2018) Effects of feeding bentonite clay upon ochratoxin A–induced immunosuppression in broiler chicks. Food Additives & Contaminants: Part A 35:3, pages 538-545.
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Z. Abidin, A. Khatoon, N. Arooj, S. Hussain, S. Ali, A. W. Manzoor & M. K. Saleemi. (2017) Estimation of ochratoxin A in poultry feed and its ingredients with special reference to temperature conditions. British Poultry Science 58:3, pages 251-255.
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Travis R. Bui-Klimke & Felicia Wu. (2015) Ochratoxin A and Human Health Risk: A Review of the Evidence. Critical Reviews in Food Science and Nutrition 55:13, pages 1860-1869.
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Xiaojiao Chang, Zidan Wu, Songling Wu, Yanshi Dai & Changpo Sun. (2015) Degradation of ochratoxin A by Bacillus amyloliquefaciens ASAG1. Food Additives & Contaminants: Part A 32:4, pages 564-571.
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Rahat Ali, Xiaoqing Guo, Haixia Lin, Qaiser M. Khan, Muhammad Ismail, Usman Waheed, Tayyaba Ali & Javed A. Bhalli. (2014) Mutant frequency in comparison to oxidative DNA damage induced by ochratoxin A in L5178Y tk+/− (3.7.2C) mouse lymphoma cells. Drug and Chemical Toxicology 37:2, pages 227-232.
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Jelka Pleadin, Nina Perši, Dragan Kovačević, Nada Vahčić, Giampiero Scortichini & Salvatore Milone. (2013) Ochratoxin A in traditional dry-cured meat products produced from sub-chronic-exposed pigs. Food Additives & Contaminants: Part A 30:10, pages 1827-1836.
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Frantisek Malir, Vladimir Ostry & Eva Novotna. (2013) Toxicity of the mycotoxin ochratoxin A in the light of recent data. Toxin Reviews 32:2, pages 19-33.
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Aisha Khatoon, Muhammad Zargham Khan, Ahrar Khan, Muhammad Kashif Saleemi & Ijaz Javed. (2013) Amelioration of Ochratoxin A-induced immunotoxic effects by silymarin and vitamin E in White Leghorn cockerels. Journal of Immunotoxicology 10:1, pages 25-31.
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Pierluigi Plastina, Alessia Fazio, Mohamed Attya, Giovanni Sindona & Bartolo Gabriele. (2012) Synthesis of analogues of ochratoxin A. Natural Product Research 26:19, pages 1799-1805.
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Christian Riebeling, Katrin Hayess, Annelieke K. Peters, Margino Steemans, Horst Spielmann, Andreas Luch & Andrea E. M. Seiler. (2012) Assaying embryotoxicity in the test tube: Current limitations of the embryonic stem cell test (EST) challenging its applicability domain. Critical Reviews in Toxicology 42:5, pages 443-464.
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S. Patharajan, V. Karthikeyan, K.R.N. Reddy & D. Spadaro. (2011) Potential of ochratoxin A production by Aspergillus carbonarius strains isolated from grapes at different ecological factors. Archives of Phytopathology and Plant Protection 44:18, pages 1802-1814.
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A.J. Chen, L.F. Huang, L.Z. Wang, D. Tang, F. Cai & W.W. Gao. (2011) Occurrence of toxigenic fungi in ochratoxin A contaminated liquorice root. Food Additives & Contaminants: Part A 28:8, pages 1091-1097.
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A.-M. Turcotte & P.M. Scott. (2011) Ochratoxin A in cocoa and chocolate sampled in Canada. Food Additives & Contaminants: Part A 28:6, pages 762-766.
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Á. Medina, E.M. Mateo, R.J. Roig, A. Blanquer & M. Jiménez. (2010) Ochratoxin A levels in the plasma of healthy blood donors from Valencia and estimation of exposure degree: comparison with previous national Spanish data. Food Additives & Contaminants: Part A 27:9, pages 1273-1284.
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T. Kuiper-Goodman, C. Hilts, S.M. Billiard, Y. Kiparissis, I.D.K. Richard & S. Hayward. (2010) Health risk assessment of ochratoxin A for all age-sex strata in a market economy. Food Additives & Contaminants: Part A 27:2, pages 212-240.
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Pierre Manda, Djédjé Sébastien Dano, James Halbin Kouadio, Aïssata Diakité, Béatrice Sangaré-Tigori, Miezan Jean Marc Ezoulin, Awa Soumahoro, Ardjouma Dembele & Gérard Fourny. (2009) Impact of industrial treatments on ochratoxin A content in artificially contaminated cocoa beans. Food Additives & Contaminants: Part A 26:7, pages 1081-1088.
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Eleonora Fusi, Federica Cheli, Raffaella Rebucci, Chiara Pecorini, Filippo Galante, Luciana Rossi, Luciano Pinotti & Antonella Baldi. (2009) Role of alpha-tocopherol in counteracting DNA damage induced by Ochratoxin A in primary porcine fibroblasts. Italian Journal of Animal Science 8:sup2, pages 301-303.
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Thomas C. Voice, David T. Long, Zoran Radovanović, James L. Atkins, Shawn P. Mcelmurry, Nedialka D. Niagolova, Plamen Dimitrov, Evangelos A. Petropoulos & Varban S. Ganev. (2006) Critical Evaluation of Environmental Exposure Agents Suspected in the Etiology of Balkan Endemic Nephropathy. International Journal of Occupational and Environmental Health 12:4, pages 369-376.
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Simone Fujii, Ricardo Marcelo Reche Ribeiro, Maria Brígida dos Santos Scholz, Elisabete Yurie Sataque Ono, Cássio Egidio C. Prete, Eiko Nakagawa Itano, Yoshio Ueno, Osamu Kawamura & Elisa Yoko Hirooka. (2006) Reliable indirect competitive ELISA used for a survey of ochratoxin A in green coffee from the North of Paraná State, Brazil. Food Additives & Contaminants 23:9, pages 902-909.
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M.A. Elaroussi, F.R. Mohamed, E.M. El Barkouky, A.M. Atta, A.M. Abdou & M.H. Hatab. (2006) Experimental ochratoxicosis in broiler chickens. Avian Pathology 35:4, pages 263-269.
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Gabriele Jedlitschky, Ulrich Hoffmann & Heyo K Kroemer. (2006) Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition. Expert Opinion on Drug Metabolism & Toxicology 2:3, pages 351-366.
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A. Esteban, M. L. Abarca, M. R. Bragulat & F. J. Cabañes. (2006) Effect of pH on ochratoxin A production by Aspergillus niger aggregate species. Food Additives & Contaminants 23:6, pages 616-622.
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Benoît Schilter, Maricel Marin-Kuan, Thierry Delatour, Sandra Nestler, Peter Mantle & Christophe Cavin. (2005) Ochratoxin A: Potential epigenetic mechanisms of toxicity and carcinogenicity. Food Additives & Contaminants 22:sup1, pages 88-93.
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Jung Woong Yoon, Sangsu Shin, JeongWoong Park, Bo Ram Lee & Sang In Lee. (2023) TLR/MyD88-Mediated Inflammation Induced in Porcine Intestinal Epithelial Cells by Ochratoxin A Affects Intestinal Barrier Function. Toxics 11:5, pages 437.
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Ziqiang Zhang, Jiajia Wang, Jianing Wang, Hui Xie, Zhikai Zhang, Lihui Shi, Xuemin Zhu, Qiongxia Lv, Xiaoguang Chen & Yumei Liu. (2023) Selenomethionine attenuates ochratoxin A-induced small intestinal injury in rabbits by activating the Nrf2 pathway and inhibiting NF-κB activation. Ecotoxicology and Environmental Safety 256, pages 114837.
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Jie Qu, Kai Liu, Shuiping Liu, Dongmei Yue, Ping Zhang, Xinru Mao, Wenmiao He, Kehe Huang & Xingxiang Chen. (2022) Taurine alleviates ochratoxin A‐induced pyroptosis in PK‐15 cells by inhibiting oxidative stress. Journal of Biochemical and Molecular Toxicology 37:2.
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Fred Mwabulili, Yanli Xie, Qian Li, Shumin Sun, Yuhui Yang & Weibin Ma. (2023) Research progress of ochratoxin a bio-detoxification. Toxicon 222, pages 107005.
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Chunyuan Tian, Minggang Wei, Xiaobin Wang, Qing Hua, Feiyan Tang, Lijun Zhao, Xuming Zhuang & Feng Luan. (2022) Electrochemiluminescence Aptasensor Based on Gd(OH)3 Nanocrystalline for Ochratoxin A Detection in Food Samples. Biosensors 12:12, pages 1141.
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Chengke Wang, Rong Tan & Dan Chen. (2018) Fluorescence method for quickly detecting ochratoxin A in flour and beer using nitrogen doped carbon dots and silver nanoparticles. Talanta 182, pages 363-370.
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Susana Viegas, Bernd Osteresch, Ana Almeida, Benedikt Cramer, Hans-Ulrich Humpf & Carla Viegas. (2017) Enniatin B and ochratoxin A in the blood serum of workers from the waste management setting. Mycotoxin Research 34:2, pages 85-90.
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Boshi Liu, Renliang Huang, Yanjun Yu, Rongxin Su, Wei Qi & Zhimin He. (2018) Gold Nanoparticle-Aptamer-Based LSPR Sensing of Ochratoxin A at a Widened Detection Range by Double Calibration Curve Method. Frontiers in Chemistry 6.
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Luca Campone, Anna Lisa Piccinelli, Rita Celano, Imma Pagano, Mariateresa Russo & Luca Rastrelli. (2018) Rapid and automated on-line solid phase extraction HPLC–MS/MS with peak focusing for the determination of ochratoxin A in wine samples. Food Chemistry 244, pages 128-135.
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Antonino Foti, Cristiano D’Andrea, Valentina Villari, Norberto Micali, Maria Donato, Barbara Fazio, Onofrio Maragò, Raymond Gillibert, Marc Lamy de la Chapelle & Pietro Gucciardi. (2018) Optical Aggregation of Gold Nanoparticles for SERS Detection of Proteins and Toxins in Liquid Environment: Towards Ultrasensitive and Selective Detection. Materials 11:3, pages 440.
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