748
Views
118
CrossRef citations to date
0
Altmetric
Research Article

Influence of particle size on drug delivery to rat alveolar macrophages following pulmonary administration of ciprofloxacin incorporated into liposomes

, , &
Pages 557-566 | Received 08 Mar 2006, Accepted 31 May 2006, Published online: 20 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (18)

Annalisa Bianchera, Francesca Buttini & Ruggero Bettini. (2020) Micro/nanosystems and biomaterials for controlled delivery of antimicrobial and anti-biofilm agents. Expert Opinion on Therapeutic Patents 30:12, pages 983-1000.
Read now
Nashwa M. Osman, Darren W. Sexton & Imran Y. Saleem. (2020) Toxicological assessment of nanoparticle interactions with the pulmonary system. Nanotoxicology 14:1, pages 21-58.
Read now
Yukimune Kanehira, Kohei Togami, Kiyomi Ishizawa, Shingo Sato, Hitoshi Tada & Sumio Chono. (2019) Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer. Pharmaceutical Development and Technology 24:9, pages 1095-1103.
Read now
Nashwa Osman, Kan Kaneko, Valeria Carini & Imran Saleem. (2018) Carriers for the targeted delivery of aerosolized macromolecules for pulmonary pathologies. Expert Opinion on Drug Delivery 15:8, pages 821-834.
Read now
M. Moreno-Sastre, M. Pastor, A. Esquisabel, E. Sans, M. Viñas, D. Bachiller & J. L. Pedraz. (2016) Stability study of sodium colistimethate-loaded lipid nanoparticles. Journal of Microencapsulation 33:7, pages 636-645.
Read now
Muhammad Sajid Hamid Akash, Kanwal Rehman & Shuqing Chen. (2016) Polymeric-based particulate systems for delivery of therapeutic proteins. Pharmaceutical Development and Technology 21:3, pages 367-378.
Read now
Mareike Klinger-Strobel, Christian Lautenschläger, Dagmar Fischer, Jochen G Mainz, Tony Bruns, Lorena Tuchscherr, Mathias W Pletz & Oliwia Makarewicz. (2015) Aspects of pulmonary drug delivery strategies for infections in cystic fibrosis – where do we stand?. Expert Opinion on Drug Delivery 12:8, pages 1351-1374.
Read now
Wing-Hin Lee, Ching-Yee Loo, Daniela Traini & Paul M Young. (2015) Nano- and micro-based inhaled drug delivery systems for targeting alveolar macrophages. Expert Opinion on Drug Delivery 12:6, pages 1009-1026.
Read now
Sabina Antonela Antoniu. (2012) Inhaled ciprofloxacin for chronic airways infections caused by Pseudomonas aeruginosa. Expert Review of Anti-infective Therapy 10:12, pages 1439-1446.
Read now
Seung Woo Chung, Taslim A. Hil-lal & Youngro Byun. (2012) Strategies for non-invasive delivery of biologics. Journal of Drug Targeting 20:6, pages 481-501.
Read now
Sumio Chono, Hirokazu Suzuki, Kohei Togami & Kazuhiro Morimoto. (2011) Efficient drug delivery to lung epithelial lining fluid by aerosolization of ciprofloxacin incorporated into PEGylated liposomes for treatment of respiratory infections. Drug Development and Industrial Pharmacy 37:4, pages 367-372.
Read now
Sumio Chono, Keita Kaneko, Eri Yamamoto, Kohei Togami & Kazuhiro Morimoto. (2010) Effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages. Drug Development and Industrial Pharmacy 36:1, pages 102-107.
Read now
Heidi M Mansour, Yun-Seok Rhee & Xiao Wu. (2009) Nanomedicine in pulmonary delivery. International Journal of Nanomedicine 4, pages 299-319.
Read now
Juan M Irache, Hesham H Salman, Carlos Gamazo & Socorro Espuelas. (2008) Mannose-targeted systems for the delivery of therapeutics. Expert Opinion on Drug Delivery 5:6, pages 703-724.
Read now
Suresh P Vyas & Kapil Khatri. (2007) Liposome-based drug delivery to alveolar macrophages. Expert Opinion on Drug Delivery 4:2, pages 95-99.
Read now

Articles from other publishers (100)

Pratsanee Hiengrach, Ariya Chindamporn & Asada Leelahavanichkul. (2023) Kazachstania pintolopesii in Blood and Intestinal Wall of Macrophage-Depleted Mice with Cecal Ligation and Puncture, the Control of Fungi by Macrophages during Sepsis. Journal of Fungi 9:12, pages 1164.
Crossref
Debabrata Ghosh Dastidar, Dipanjan Ghosh, Swarnasree Ghosh & Gopal Chakrabarti. (2023) Current Therapeutic Strategies and Possible Effective Drug Delivery Strategies against COVID-19. Current Drug Delivery 20:10, pages 1441-1464.
Crossref
Mohit Kumar, Ayah R. Hilles, Samah Hamed Almurisi, Amit Bhatia & Syed Mahmood. (2023) Micro and nano-carriers-based pulmonary drug delivery system: Their current updates, challenges, and limitations – A review. JCIS Open 12, pages 100095.
Crossref
Mingze Xu, Yuming Qi, Gaoshuo Liu, Yuanqing Song, Xingya Jiang & Bujie Du. (2023) Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance . ACS Nano 17:21, pages 20825-20849.
Crossref
Yutong Guo, Zeyuan Mao, Fang Ran, Jihong Sun, Jingfeng Zhang, Guihong Chai & Jian Wang. (2023) Nanotechnology-Based Drug Delivery Systems to Control Bacterial-Biofilm-Associated Lung Infections. Pharmaceutics 15:11, pages 2582.
Crossref
Ludan Yue, Xueyang Zhang, Chenchen Zhao, Rongchang Chen, Xiaoyuan Chen & Lang Rao. (2023) Inhaled drug delivery: Past, present, and future. Nano Today 52, pages 101942.
Crossref
Alaa S. Tulbah. (2023) In vitro bio-characterization of solid lipid nanoparticles of favipiravir in A549 human lung epithelial cancer cells. Journal of Taibah University Medical Sciences 18:5, pages 1076-1086.
Crossref
Ho Wan Chan, Stephanie Chow, Xinyue Zhang, Philip Chi Lip Kwok & Shing Fung Chow. (2023) Role of Particle Size in Translational Research of Nanomedicines for Successful Drug Delivery: Discrepancies and Inadequacies. Journal of Pharmaceutical Sciences 112:9, pages 2371-2384.
Crossref
Jing Wen, Dale Creaven, Xiangshu Luan & Jiemin Wang. (2023) Comparison of immunotherapy mediated by apoptotic bodies, microvesicles and exosomes: apoptotic bodies’ unique anti-inflammatory potential. Journal of Translational Medicine 21:1.
Crossref
E. de Pablo, P. ÓConnell, R. Fernández-García, S. Marchand, A. Chauzy, Frederic Tewes, M.A. Dea-Ayuela, Dinesh Kumar, F. Bolás, M.P. Ballesteros, J.J. Torrado, A.M. Healy & D.R. Serrano. (2023) Targeting lung macrophages for fungal and parasitic pulmonary infections with innovative amphotericin B dry powder inhalers. International Journal of Pharmaceutics, pages 122788.
Crossref
Helga K. Ruiz, Dolores R. Serrano, Lourdes Calvo & Albertina Cabañas. (2022) Current Treatments for COVID-19: Application of Supercritical Fluids in the Manufacturing of Oral and Pulmonary Formulations. Pharmaceutics 14:11, pages 2380.
Crossref
Behjat Sheikholeslami, Nga Wing Lam, Kamal Dua & Mehra Haghi. (2022) Exploring the impact of physicochemical properties of liposomal formulations on their in vivo fate. Life Sciences 300, pages 120574.
Crossref
Benedikt C. Huck, Durairaj Thiyagarajan, Aghiad Bali, Annette Boese, Karen F. W. Besecke, Constantin Hozsa, Robert K. Gieseler, Marcus Furch, Cristiane Carvalho‐Wodarz, Franziska Waldow, Dominik Schwudke, Olga Metelkina, Alexander Titz, Hanno Huwer, Konrad Schwarzkopf, Jessica Hoppstädter, Alexandra K. Kiemer, Marcus Koch, Brigitta Loretz & Claus‐Michael Lehr. (2022) Nano‐in‐Microparticles for Aerosol Delivery of Antibiotic‐Loaded, Fucose‐Derivatized, and Macrophage‐Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery. Advanced Healthcare Materials 11:11.
Crossref
Jung Won Kwon, Hailian Quan, Juha Song, Hyewon Chung, Daun Jung, Jung Joo Hong, Yi Rang Na & Seung Hyeok Seok. (2022) Liposomal Dexamethasone Reduces A/H1N1 Influenza-Associated Morbidity in Mice. Frontiers in Microbiology 13.
Crossref
Maharshi Thalla & Subham Banerjee. 2022. Nanoengineering of Biomaterials. Nanoengineering of Biomaterials 371 410 .
Yingbo Li, Jie Yang, Guangying Gu, Xu Guo, Chunbo He, Jiemei Sun, Hongyan Zou, Hongbin Wang, Shuang Liu, Xiaona Li, Shujun Zhang, Kai Wang, Lili Yang, Ying Jiang, Lina Wu & Xilin Sun. (2022) Pulmonary Delivery of Theranostic Nanoclusters for Lung Cancer Ferroptosis with Enhanced Chemodynamic/Radiation Synergistic Therapy. Nano Letters 22:3, pages 963-972.
Crossref
Atef A. Hassan, Rasha M.H. Sayed-ElAhl, Ahmed M.A. El-Hamaky, Mogda K. Mansour & Noha H. Oraby. 2022. Copper Nanostructures: Next-Generation of Agrochemicals for Sustainable Agroecosystems. Copper Nanostructures: Next-Generation of Agrochemicals for Sustainable Agroecosystems 507 534 .
Anand Maurya, Anurag Kumar Singh, Bhuwanendra Singh, Nidhi Singh, Sachin Kumar Agrahari, Arati Rai & Gopal Kumar Rai. 2022. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases 107 124 .
Anil K. Philip, Betty Annie Samuel, Kamran Ashraf & Md. Faiyazuddin. 2022. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases 609 621 .
Heidrun Steinle, Josefin Weber, Sandra Stoppelkamp, Katharina Große-Berkenbusch, Sonia Golombek, Marbod Weber, Tuba Canak-Ipek, Sarah-Maria Trenz, Christian Schlensak & Meltem Avci-Adali. (2021) Delivery of synthetic mRNAs for tissue regeneration. Advanced Drug Delivery Reviews 179, pages 114007.
Crossref
Yi Guo, Hriday Bera, Changzhi Shi, Li Zhang, Dongmei Cun & Mingshi Yang. (2021) Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines. Acta Pharmaceutica Sinica B 11:8, pages 2565-2584.
Crossref
Omar A. Elkady, Layla M. Saleh, Mina Ibrahim Tadros & Hanan M. El-laithy. (2021) Nebulization of Risedronate Sodium Microspheres for Potential Attenuation of Pulmonary Emphysema: a Promising New Insight of Alveolar Macrophage Apoptosis. AAPS PharmSciTech 22:5.
Crossref
Pragya Prasanna, Shweta Rathee, Arun Upadhyay & Sulakshana Sulakshana. (2021) Nanotherapeutics in the treatment of acute respiratory distress syndrome. Life Sciences 276, pages 119428.
Crossref
Florian Weber, Daniela C. Ivan, Steven T. Proulx, Giuseppe Locatelli, Simone Aleandri & Paola Luciani. (2021) Beyond Trial and Error: A Systematic Development of Liposomes Targeting Primary Macrophages. Advanced NanoBiomed Research 1:3.
Crossref
Maksim V. Baranov, Manoj Kumar, Stefano Sacanna, Shashi Thutupalli & Geert van den Bogaart. (2021) Modulation of Immune Responses by Particle Size and Shape. Frontiers in Immunology 11.
Crossref
Michael Y.T. Chow, Rachel Yoon Kyung Chang & Hak-Kim Chan. (2021) Inhalation delivery technology for genome-editing of respiratory diseases. Advanced Drug Delivery Reviews 168, pages 217-228.
Crossref
Tao Wan & Yuan Ping. (2021) Delivery of genome-editing biomacromolecules for treatment of lung genetic disorders. Advanced Drug Delivery Reviews 168, pages 196-216.
Crossref
Debabrata Ghosh Dastidar, Dipanjan Ghosh, Swarnasree Ghosh & Gopal Chakrabarti. 2021. Targeting Cellular Signalling Pathways in Lung Diseases. Targeting Cellular Signalling Pathways in Lung Diseases 847 902 .
Bwalya A. Witika, Vincent J. Smith & Roderick B. Walker. (2020) Top-Down Synthesis of a Lamivudine-Zidovudine Nano Co-Crystal. Crystals 11:1, pages 33.
Crossref
Helena Rouco, Patricia Diaz-Rodriguez, Diana P. Gaspar, Lídia M. D. Gonçalves, Miguel Cuerva, Carmen Remuñán-López, António J. Almeida & Mariana Landin. (2020) Rifabutin-Loaded Nanostructured Lipid Carriers as a Tool in Oral Anti-Mycobacterial Treatment of Crohn’s Disease. Nanomaterials 10:11, pages 2138.
Crossref
Kuiyu Meng, Dongmei Chen, Fei Yang, Aoxue Zhang, Yanfei Tao, Wei Qu, Yuanhu Pan, Haihong Hao & Shuyu Xie. (2020) Intracellular delivery, accumulation, and discrepancy in antibacterial activity of four enrofloxacin-loaded fatty acid solid lipid nanoparticles. Colloids and Surfaces B: Biointerfaces 194, pages 111196.
Crossref
Amber VuPaul B. McCray, Jr., Jr.. (2020) New Directions in Pulmonary Gene Therapy. Human Gene Therapy 31:17-18, pages 921-939.
Crossref
Tuangrat Praphawatvet, Jay I. Peters & Robert O. WilliamsIIIIII. (2020) Inhaled nanoparticles–An updated review. International Journal of Pharmaceutics 587, pages 119671.
Crossref
Yi Rang Na, Jung Won Kwon, Da Young Kim, Hyewon Chung, Juha Song, Daun Jung, Hailian Quan, Daesik Kim, Jin-Soo Kim, Young Wook Ju, Wonshik Han, Han Suk Ryu, Yun-Sang Lee, Jung Joo Hong & Seung Hyeok Seok. (2020) Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages. Cell Reports 31:6, pages 107643.
Crossref
Bwalya A. Witika, Vincent J. Smith & Roderick B. Walker. (2020) Quality by Design Optimization of Cold Sonochemical Synthesis of Zidovudine-Lamivudine Nanosuspensions. Pharmaceutics 12:4, pages 367.
Crossref
Monica Joshi, Mangal Nagarsenkar & Bala Prabhakar. (2020) Albumin nanocarriers for pulmonary drug delivery: An attractive approach. Journal of Drug Delivery Science and Technology 56, pages 101529.
Crossref
Kohei Togami. (2020) Intrapulmonary Pharmacokinetics and Drug Distribution Characteristics for the Treatment of Respiratory Diseases呼吸器疾患治療のための薬物の肺内動態及び肺組織分布特性の解明. YAKUGAKU ZASSHI 140:3, pages 345-354.
Crossref
Kenward Vong, Katsunori Tanaka & Koichi Fukase. 2020. Handbook of In Vivo Chemistry in Mice. Handbook of In Vivo Chemistry in Mice 489 529 .
Patricia Marcianes, Sofia Negro, Emilia Barcia, Consuelo Montejo & Ana Fernández-Carballido. (2019) Potential Active Targeting of Gatifloxacin to Macrophages by Means of Surface-Modified PLGA Microparticles Destined to Treat Tuberculosis. AAPS PharmSciTech 21:1.
Crossref
Arcadia Woods, Teodora Andrian, Gemma Sharp, Elif Melis Bicer, Kalliopi-Kelli A. Vandera, Ayasha Patel, Ian Mudway, Lea Ann Dailey & Ben Forbes. (2020) Development of new in vitro models of lung protease activity for investigating stability of inhaled biological therapies and drug delivery systems. European Journal of Pharmaceutics and Biopharmaceutics 146, pages 64-72.
Crossref
Qiaoyu Liu, Jian Guan, Lu Qin, Xin Zhang & Shirui Mao. (2020) Physicochemical properties affecting the fate of nanoparticles in pulmonary drug delivery. Drug Discovery Today 25:1, pages 150-159.
Crossref
Amir Hossein Bahmanpour, Maryam Ghaffari, Sajjad Ashraf & Masoud Mozafari. 2020. Nanoengineered Biomaterials for Advanced Drug Delivery. Nanoengineered Biomaterials for Advanced Drug Delivery 561 579 .
Caleb F. Anderson, Maria E. Grimmett, Christopher J. Domalewski & Honggang Cui. (2019) Inhalable nanotherapeutics to improve treatment efficacy for common lung diseases. WIREs Nanomedicine and Nanobiotechnology 12:1.
Crossref
Gustavo Lou, Giulia Anderluzzi, Stuart Woods, Craig W. Roberts & Yvonne Perrie. (2019) A novel microfluidic-based approach to formulate size-tuneable large unilamellar cationic liposomes: Formulation, cellular uptake and biodistribution investigations. European Journal of Pharmaceutics and Biopharmaceutics 143, pages 51-60.
Crossref
Javaid, Yasmeen & Choi. (2019) Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods. Pharmaceutics 11:9, pages 441.
Crossref
Jiaqi Li, Huangliang Zheng, Lu Qin, En-Yu Xu, Linglong Yang, Lan Zhang, Xiaofei Zhang, Linlin Fan, Moritz Beck-Broichsitter, Uwe Muenster, Linc Chen, Yuyang Zhang & Shirui Mao. (2019) In vitro–in vivo correlation of inhalable budesonide-loaded large porous particles for sustained treatment regimen of asthma. Acta Biomaterialia 96, pages 505-516.
Crossref
Jinxiang Xi & Mohamed Talaat. (2019) Nanoparticle Deposition in Rhythmically Moving Acinar Models with Interalveolar Septal Apertures. Nanomaterials 9:8, pages 1126.
Crossref
Satoshi Uchida & Kazunori Kataoka. (2019) Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA . Journal of Biomedical Materials Research Part A 107:5, pages 978-990.
Crossref
Zimei WuBen KohLisa M. LawrenceManju KanamalaBregina PoolDarren SvirskisNicola DalbethJonathan W. AstinKathryn E. CrosierPhilip S. CrosierChristopher J. Hall. (2019) Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function. Zebrafish 16:2, pages 171-181.
Crossref
Michael Katz, Anthony Fargnoli, Sarah Gubara, Kenneth Fish, Thomas Weber, Charles Bridges, Roger Hajjar & Kiyotake Ishikawa. (2019) Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer. Journal of Cardiovascular Development and Disease 6:1, pages 8.
Crossref
Gizem Osman, Jason Rodriguez, Sze Yan Chan, Jane Chisholm, Gregg Duncan, Namho Kim, Amanda L. Tatler, Kevin M. Shakesheff, Justin Hanes, Jung Soo Suk & James E. Dixon. (2018) PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy. Journal of Controlled Release 285, pages 35-45.
Crossref
Duy-Khiet Ho, Ana Costa, Chiara De Rossi, Cristiane de Souza Carvalho-Wodarz, Brigitta Loretz & Claus-Michael Lehr. (2018) Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization, and Influence of Size on Cellular Uptake. Molecular Pharmaceutics 15:3, pages 1081-1096.
Crossref
Abdullah Scott, Krishna Prasad Vadalasetty, André Chwalibog & Ewa Sawosz. (2018) Copper nanoparticles as an alternative feed additive in poultry diet: a review. Nanotechnology Reviews 7:1, pages 69-93.
Crossref
Shuyu Xie, Fei Yang, Yanfei Tao, Dongmei Chen, Wei Qu, Lingli Huang, Zhenli Liu, Yuanhu Pan & Zonghui Yuan. (2017) Enhanced intracellular delivery and antibacterial efficacy of enrofloxacin-loaded docosanoic acid solid lipid nanoparticles against intracellular Salmonella. Scientific Reports 7:1.
Crossref
Ralph Tripp & Jarod Hanson. 2016. Advances in Pulmonary Drug Delivery. Advances in Pulmonary Drug Delivery 93 130 .
Young H. Lim, Kristin M. Tiemann, David A. Hunstad, Mahmoud Elsabahy & Karen L. Wooley. (2016) Polymeric nanoparticles in development for treatment of pulmonary infectious diseases. WIREs Nanomedicine and Nanobiotechnology 8:6, pages 842-871.
Crossref
Namho Kim, Gregg A. Duncan, Justin Hanes & Jung Soo Suk. (2016) Barriers to inhaled gene therapy of obstructive lung diseases: A review. Journal of Controlled Release 240, pages 465-488.
Crossref
Keita Kaneko, Kohei Togami, Eri Yamamoto, Shujun Wang, Kazuhiro Morimoto, Shirou Itagaki & Sumio Chono. (2016) Sustained distribution of aerosolized PEGylated liposomes in epithelial lining fluids on alveolar surfaces. Drug Delivery and Translational Research 6:5, pages 565-571.
Crossref
Paola Pedata, Claudia Petrarca, Elpidio Maria Garzillo & Mario Di Gioacchino. (2016) Immunotoxicological impact of occupational and environmental nanoparticles exposure: The influence of physical, chemical, and combined characteristics of the particles. International Journal of Immunopathology and Pharmacology 29:3, pages 343-353.
Crossref
Moeko Taki, Tatsuaki Tagami, Kaori Fukushige & Tetsuya Ozeki. (2016) Fabrication of nanocomposite particles using a two-solution mixing-type spray nozzle for use in an inhaled curcumin formulation. International Journal of Pharmaceutics 511:1, pages 104-110.
Crossref
Shadabul Haque, Michael R. Whittaker, Michelle P. McIntosh, Colin W. Pouton & Lisa M. Kaminskas. (2016) Disposition and safety of inhaled biodegradable nanomedicines: Opportunities and challenges. Nanomedicine: Nanotechnology, Biology and Medicine 12:6, pages 1703-1724.
Crossref
Kohei Togami, Sumio Chono & Hitoshi Tada. (2016) Alteration in Intrapulmonary Pharmacokinetics of Aerosolized Model Compounds Due to Disruption of the Alveolar Epithelial Barriers Following Bleomycin-Induced Pulmonary Fibrosis in Rats. Journal of Pharmaceutical Sciences 105:3, pages 1327-1334.
Crossref
Remigijus Vasiliauskas, Dongfei Liu, Salvatore Cito, Hongbo Zhang, Mohammad-Ali Shahbazi, Tiina Sikanen, Linas Mazutis & Hélder A. Santos. (2015) Simple Microfluidic Approach to Fabricate Monodisperse Hollow Microparticles for Multidrug Delivery. ACS Applied Materials & Interfaces 7:27, pages 14822-14832.
Crossref
Chen Shi, Saeed Ahmad Khan, Kaiping Wang & Marc Schneider. (2015) Improved delivery of the natural anticancer drug tetrandrine. International Journal of Pharmaceutics 479:1, pages 41-51.
Crossref
Brijeshkumar Patel, Nilesh Gupta & Fakhrul Ahsan. (2015) Particle engineering to enhance or lessen particle uptake by alveolar macrophages and to influence the therapeutic outcome. European Journal of Pharmaceutics and Biopharmaceutics 89, pages 163-174.
Crossref
Nadège Grabowski, Hervé Hillaireau, Juliette Vergnaud & Elias Fattal. 2015. Targeted Drug Delivery : Concepts and Design. Targeted Drug Delivery : Concepts and Design 689 732 .
Romain Merlos, Karim Amighi & Nathalie Wauthoz. (2014) Recent Developments in Inhaled Triazoles Against Invasive Pulmonary Aspergillosis. Current Fungal Infection Reports 8:4, pages 331-342.
Crossref
Chetna Dhand, Molamma P. Prabhakaran, Roger W. Beuerman, R. Lakshminarayanan, Neeraj Dwivedi & Seeram Ramakrishna. (2014) Role of size of drug delivery carriers for pulmonary and intravenous administration with emphasis on cancer therapeutics and lung-targeted drug delivery. RSC Adv. 4:62, pages 32673-32689.
Crossref
Amit K. Goyal, Goutam Rath & Basant Malik. 2014. Molecular Vaccines. Molecular Vaccines 579 601 .
Junlan Chuan, Yanzhen Li, Likai Yang, Xun Sun, Qiang Zhang, Tao Gong & Zhirong Zhang. (2013) Enhanced rifampicin delivery to alveolar macrophages by solid lipid nanoparticles. Journal of Nanoparticle Research 15:5.
Crossref
Pritam Sahota, James Popp, Jerry Hardisty & Chirukandath GopinathDavid Lewis & Tom McKevitt. 2013. Toxicologic Pathology. Toxicologic Pathology 367 420 .
Mohammad Ali Faramarzi & Armin Sadighi. (2013) Insights into biogenic and chemical production of inorganic nanomaterials and nanostructures. Advances in Colloid and Interface Science 189-190, pages 1-20.
Crossref
Hsiao-Wen Wang, Ping-Lun Jiang, Shen-Fu Lin, Hung-Jun Lin, Keng-Liang Ou, Win-Ping Deng, Lin-Wen Lee, Yi-You Huang, Pi-Hui Liang & Der-Zen Liu. (2013) Application of galactose-modified liposomes as a potent antigen presenting cell targeted carrier for intranasal immunization. Acta Biomaterialia 9:3, pages 5681-5688.
Crossref
Joanne M Ramsey, Alan Hibbitts, James Barlow, Ciara Kelly, Neeraj Sivadas & Sally-Ann Cryan. (2013) ‘Smart’ non-viral delivery systems for targeted delivery of RNAi to the lungs. Therapeutic Delivery 4:1, pages 59-76.
Crossref
Kazuhiro Morimoto. (2013) Designs of Optimized Microbial Therapy Systems of Respiratory Infections呼吸器感染症の抗菌薬を用いた最適治療法の構築. YAKUGAKU ZASSHI 133:1, pages 81-92.
Crossref
Ying-Zheng Zhao, Xing Li, Cui-Tao Lu, Yan-Yan Xu, Hai-Feng Lv, Dan-Dan Dai, Lu Zhang, Chang-Zheng Sun, Wei Yang, Xiao-Kun Li, Ya-Ping Zhao, Hong-Xing Fu, Lu Cai, Min Lin, Li-Juan Chen & Ming Zhang. (2011) Experiment on the feasibility of using modified gelatin nanoparticles as insulin pulmonary administration system for diabetes therapy. Acta Diabetologica 49:4, pages 315-325.
Crossref
Nazrul Islam & Matthew J. Cleary. (2012) Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery – A review for multidisciplinary researchers. Medical Engineering & Physics 34:4, pages 409-427.
Crossref
Olivia M. Merkel, Mengyao Zheng, Heiko Debus & Thomas Kissel. (2011) Pulmonary Gene Delivery Using Polymeric Nonviral Vectors. Bioconjugate Chemistry 23:1, pages 3-20.
Crossref
Peter Greaves. 2012. Histopathology of Preclinical Toxicity Studies. Histopathology of Preclinical Toxicity Studies 207 261 .
Ciara Kelly, Caroline Jefferies & Sally-Ann Cryan. (2011) Targeted Liposomal Drug Delivery to Monocytes and Macrophages. Journal of Drug Delivery 2011, pages 1-11.
Crossref
Wean Sin Cheow, Matthew Wook Chang & Kunn Hadinoto. (2011) The roles of lipid in anti-biofilm efficacy of lipid–polymer hybrid nanoparticles encapsulating antibiotics. Colloids and Surfaces A: Physicochemical and Engineering Aspects 389:1-3, pages 158-165.
Crossref
Wean Sin Cheow, Mabel Li Ling Ng, Katherine Kho & Kunn Hadinoto. (2011) Spray-freeze-drying production of thermally sensitive polymeric nanoparticle aggregates for inhaled drug delivery: Effect of freeze-drying adjuvants. International Journal of Pharmaceutics 404:1-2, pages 289-300.
Crossref
Helen C. Chen, Bingbing Sun, Kenny K. Tran & Hong Shen. (2011) Effects of particle size on toll-like receptor 9-mediated cytokine profiles. Biomaterials 32:6, pages 1731-1737.
Crossref
K.D. Bruce, G.B. Rogers & N. Patel. (2011) Microbiological insights into respiratory infections and the opportunities for inhaled therapy. Journal of Drug Delivery Science and Technology 21:4, pages 301-309.
Crossref
Janani Swaminathan & Carsten Ehrhardt. 2011. Controlled Pulmonary Drug Delivery. Controlled Pulmonary Drug Delivery 313 334 .
Katherine Kho, Wean Sin Cheow, Ru Hui Lie & Kunn Hadinoto. (2010) Aqueous re-dispersibility of spray-dried antibiotic-loaded polycaprolactone nanoparticle aggregates for inhaled anti-biofilm therapy. Powder Technology 203:3, pages 432-439.
Crossref
Wean Sin Cheow, Matthew Wook Chang & Kunn Hadinoto. (2010) Antibacterial Efficacy of Inhalable Levofloxacin-Loaded Polymeric Nanoparticles Against E. coli Biofilm Cells: The Effect of Antibiotic Release Profile. Pharmaceutical Research 27:8, pages 1597-1609.
Crossref
Katherine Kho & Kunn Hadinoto. (2010) Effects of excipient formulation on the morphology and aqueous re-dispersibility of dry-powder silica nano-aggregates. Colloids and Surfaces A: Physicochemical and Engineering Aspects 359:1-3, pages 71-81.
Crossref
Katherine Kho & Kunn Hadinoto. (2010) Aqueous re-dispersibility characterization of spray-dried hollow spherical silica nano-aggregates. Powder Technology 198:3, pages 354-363.
Crossref
Yu Seok Youn, Kang Choon Lee, You Han Bae, Kun Na & Eun Seong Lee. 2009. Delivery Technologies for Biopharmaceuticals. Delivery Technologies for Biopharmaceuticals 227 244 .
Sumio Chono, Rie Fukuchi, Toshinobu Seki & Kazuhiro Morimoto. (2009) Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery. Journal of Controlled Release 137:2, pages 104-109.
Crossref
Rogério S Rosada, Lucimara Gaziola de la Torre, Fabiani G Frantz, Ana PF Trombone, Carlos R Zárate-Bladés, Denise M Fonseca, Patrícia RM Souza, Izaíra T Brandão, Ana P Masson, Édson G Soares, Simone G Ramos, Lúcia H Faccioli, Célio L Silva, Maria HA Santana & Arlete AM Coelho-Castelo. (2008) Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes. BMC Immunology 9:1.
Crossref
Juliane Nguyen, Terry W.J. Steele, Olivia Merkel, Regina Reul & Thomas Kissel. (2008) Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy. Journal of Controlled Release 132:3, pages 243-251.
Crossref
S.M. Hwang, D.D. Kim, S.J. Chung & C.K. Shim. (2008) Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis. Journal of Controlled Release 129:2, pages 100-106.
Crossref
Laszlo M. HoeselMichael A. FlierlAndreas D. NiederbichlerDaniel RittirschShannon D. McClintockJayne S. ReubenMatthew J. PiankoWilliam StoneHongsong YangMilton SmithJ. Vidya SarmaPeter A. Ward. (2008) Ability of Antioxidant Liposomes to Prevent Acute and Progressive Pulmonary Injury. Antioxidants & Redox Signaling 10:5, pages 963-972.
Crossref
Maryam Amidi, Kevin M. Krudys, Cor J. Snel, Daan J.A. Crommelin, Oscar E. Della Pasqua, Wim E. Hennink & Wim Jiskoot. (2008) Efficacy of pulmonary insulin delivery in diabetic rats: Use of a model-based approach in the evaluation of insulin powder formulations. Journal of Controlled Release 127:3, pages 257-266.
Crossref
Wei Yang, Jay I. Peters & Robert O. WilliamsIIIIII. (2008) Inhaled nanoparticles—A current review. International Journal of Pharmaceutics 356:1-2, pages 239-247.
Crossref
Sumio Chono, Tomoharu Tanino, Toshinobu Seki & Kazuhiro Morimoto. (2008) Efficient drug targeting to rat alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratory intracellular parasitic infections. Journal of Controlled Release 127:1, pages 50-58.
Crossref
Sumio CHONO. (2007) Development of Drug Delivery Systems for Targeting to Macrophagesマクロファージを標的とするドラッグデリバリーシステムの構築. YAKUGAKU ZASSHI 127:9, pages 1419-1430.
Crossref
John S. Patton & Peter R. Byron. (2007) Inhaling medicines: delivering drugs to the body through the lungs. Nature Reviews Drug Discovery 6:1, pages 67-74.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.