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Drug Delivery Volume 15, 2008 - Issue 8
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Research Article

Effect of Oil-in-Water Submicron Emulsion Surface Charge on Oral Absorption of a Poorly Water-Soluble Drug in Rats

Stéphanie Poullain-Termeau Laboratoire de Pharmacie Galénique, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, Paris, FranceCorrespondence[email protected]
,
Sylvie Crauste-Manciet Laboratoire de Pharmacie Galénique, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, Paris, France
,
Denis Brossard Laboratoire de Pharmacie Galénique, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, Paris, France
,
Saleh Muhamed Laboratoire de Pharmacie Galénique, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, Paris, France
,
Georges Nicolaos Laboratoire de Pharmacie Galénique, Faculté des Sciences Pharmaceutiques et Biologiques, Université Paris Descartes, Paris, France
,
Robert Farinotti Laboratoire de Pharmacie Clinique, Faculté de Pharmacie, UPRES 2706, Université Paris XI, Châtenay Malabry, France
,
Christine Barthélémy Laboratoire de Pharmacie Galénique et Biopharmacie, Faculté de Pharmacie, Université Lille 2, Lille, France
,
Hugues Robert Laboratoire de Pharmacie Galénique et Biopharmacie, Faculté de Pharmacie, Université Lille 2, Lille, France
&
Pascal Odou Laboratoire de Pharmacie Galénique et Biopharmacie, Faculté de Pharmacie, Université Lille 2, Lille, France
 show all
Pages 503-514 | Received 24 Jan 2008, Accepted 30 Mar 2008, Published online: 06 Nov 2008

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Zhen Li, Jinxu Cao, Heran Li, Hongzhuo Liu, Fei Han, Zhenyun Liu, Chao Tong & Sanming Li. (2016) Self-assembled drug delivery system based on low-molecular-weight bis-amide organogelator: synthesis, properties and in vivo evaluation. Drug Delivery 23:8, pages 3168-3178.
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Mona Hassan Aburahma. (2016) Insights on novel particulate self-assembled drug delivery beads based on partial inclusion complexes between triglycerides and cyclodextrins. Drug Delivery 23:7, pages 2205-2219.
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Estelle Sigward, Nathalie Mignet, Patrice Rat, Mélody Dutot, Saleh Muhamed, Jean-Michel Guigner, Daniel Scherman, Denis Brossard & Sylvie Crauste-Manciet. (2013) Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions. International Journal of Nanomedicine 8, pages 611-625.
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H. Zheng & J. Rao. 2023. Bioactive Delivery Systems for Lipophilic Nutraceuticals. Bioactive Delivery Systems for Lipophilic Nutraceuticals 148 180 .
Wei Lu, Alan L. Kelly, Pierce Maguire, Hongzhou Zhang, Catherine Stanton & Song Miao. (2016) Correlation of Emulsion Structure with Cellular Uptake Behavior of Encapsulated Bioactive Nutrients: Influence of Droplet Size and Interfacial Structure. Journal of Agricultural and Food Chemistry 64:45, pages 8659-8666.
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Hira Choudhury, Bapi Gorain, Sanmoy Karmakar, Easha Biswas, Goutam Dey, Rajib Barik, Mahitosh Mandal & Tapan Kumar Pal. (2014) Improvement of cellular uptake, in vitro antitumor activity and sustained release profile with increased bioavailability from a nanoemulsion platform. International Journal of Pharmaceutics 460:1-2, pages 131-143.
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Kentaro Yano, Takumi Tomono, Riyo Sakai, Takashi Kano, Kaori Morimoto, Yukio Kato & Takuo Ogihara. (2013) Contribution of Radixin to P-Glycoprotein Expression and Transport Activity in Mouse Small Intestine In Vivo. Journal of Pharmaceutical Sciences 102:8, pages 2875-2881.
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Bapi Gorain, Hira Choudhury, Easha Biswas, Anwesha Barik, P. Jaisankar & Tapan Kumar Pal. (2013) A novel approach for nanoemulsion components screening and nanoemulsion assay of olmesartan medoxomil through a developed and validated HPLC method. RSC Advances 3:27, pages 10887.
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Yan Li, Jinkai Zheng, Hang Xiao & David Julian McClements. (2012) Nanoemulsion-based delivery systems for poorly water-soluble bioactive compounds: Influence of formulation parameters on polymethoxyflavone crystallization. Food Hydrocolloids 27:2, pages 517-528.
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Héloïse Ragelle, Sylvie Crauste-Manciet, Johanne Seguin, Denis Brossard, Daniel Scherman, Philippe Arnaud & Guy G. Chabot. (2012) Nanoemulsion formulation of fisetin improves bioavailability and antitumour activity in mice. International Journal of Pharmaceutics 427:2, pages 452-459.
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Ming-Jun Tsai, Yaw-Bin Huang, Pao-Chu Wu, Yaw-Syan Fu, Yao-Ren Kao, Jia-You Fang & Yi-Hung Tsai. (2011) Oral Apomorphine Delivery from Solid Lipid Nanoparticles with Different Monostearate Emulsifiers: Pharmacokinetic and Behavioral Evaluations. Journal of Pharmaceutical Sciences 100:2, pages 547-557.
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Takashi Kano, Chihaya Kakinuma, Sho Wada, Kaori Morimoto & Takuo Ogihara. (2011) Enhancement of Drug Solubility and Absorption by Copolymers of 2-Methacryloyloxyethyl Phosphorylcholine and n-Butyl Methacrylate. Drug Metabolism and Pharmacokinetics 26:1, pages 79-86.
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Gert Fricker, Torsten Kromp, Armin Wendel, Alfred Blume, Jürgen Zirkel, Herbert Rebmann, Constanze Setzer, Ralf-Olaf Quinkert, Frank Martin & Christel Müller-Goymann. (2010) Phospholipids and Lipid-Based Formulations in Oral Drug Delivery. Pharmaceutical Research 27:8, pages 1469-1486.
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Chih-Chieh Chen, Tung-Hu Tsai, Zih-Rou Huang & Jia-You Fang. (2010) Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: Physicochemical characterization and pharmacokinetics. European Journal of Pharmaceutics and Biopharmaceutics 74:3, pages 474-482.
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