Advanced search
Publication Cover
Drug Delivery Volume 27, 2020 - Issue 1
Submit an article Journal homepage
3,477
Views
41
CrossRef citations to date
0
Altmetric
Research Article

Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from Selaginella doederleinii extract by amorphous solid dispersion

Bing Chena Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China;b Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaView further author information
,
Xuewen Wangb Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaView further author information
,
Yanyan Zhangb Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaView further author information
,
Kangping Huangb Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaView further author information
,
Hao Liub Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaView further author information
,
Dafen Xub Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaView further author information
,
Shaoguang Lib Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaView further author information
,
Qicai Liua Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China;b Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, ChinaView further author information
,
Jianyong Huangd Department of Pharmaceutical, Fujian Medical University Union Hospital, Fuzhou, ChinaCorrespondence[email protected]
View further author information
,
Hong Yaob Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, China;e Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, Fujian Medical University, Fuzhou, ChinaCorrespondence[email protected]
View further author information
&
Xinhua Lina Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China;b Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical University, Fuzhou, China;c Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, ChinaCorrespondence[email protected]
View further author information
 show all
Pages 309-322 | Received 12 Nov 2019, Accepted 13 Jan 2020, Published online: 10 Feb 2020

Citations (41)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Ziwei Huang, Shanli Zhang, Zehui Qin, Gaoxiang Ai, Minhua Li, Shiting Gong, Yuhong Liu, Huifang Zeng, Jiannan Chen, Ziren Su & Zhengquan Lai. (2024) Supersaturated Drug Delivery System of Oxyberberine Based on Cyclodextrin Nanoaggregates: Preparation, Characterization, and in vivo Application. International Journal of Nanomedicine 19, pages 5297-5316.
Read now
Qing Lin, Yafei Jing, Cailing Yan, Xinyi Chen, Qiong Zhang, Xinhua Lin, Yunlu Xu & Bing Chen. (2024) Design and Application of pH-Responsive Liposomes for Site-Specific Delivery of Cytotoxin from Cobra Venom. International Journal of Nanomedicine 19, pages 5381-5395.
Read now
Yang Xie, Xiao-Chang Yao, Lei-Hong Tan, Hong-Ping Long, Ping-Sheng Xu, Jing Li & Gui-Shan Tan. (2022) Trichocladabiflavone A, a chalcone-flavonone type biflavonoid from Selaginella trichoclada Alsto. Natural Product Research 36:7, pages 1797-1802.
Read now
Rudra Pangeni, Laxman Subedi, Saurav Kumar Jha, Seho Kweon, Seo-Hee Kang, Kwan-Young Chang, Jeong Uk Choi, Youngro Byun & Jin Woo Park. (2020) Improvements in the Oral Absorption and Anticancer Efficacy of an Oxaliplatin-Loaded Solid Formulation: Pharmacokinetic Properties in Rats and Nonhuman Primates and the Effects of Oral Metronomic Dosing on Colorectal Cancer. International Journal of Nanomedicine 15, pages 7719-7743.
Read now
Yuanyuan Wang, Chao Pi, Xianhu Feng, Yi Hou, Ling Zhao & Yumeng Wei. (2020) The Influence of Nanoparticle Properties on Oral Bioavailability of Drugs. International Journal of Nanomedicine 15, pages 6295-6310.
Read now

Articles from other publishers (36)

Dinesh Kumar Patel. (2024) Biological Importance and Therapeutic Potential of Delicaflavone against Cancerous Disorders: A Rare Naturally Occurring Biflavonoids of Selaginella Species. Current Traditional Medicine 10:5.
Crossref
Amran Hossain, Md. Thohid Rayhan, Md Hosne Mobarak, Md Israfil Hossain Rimon, Nayem Hossain, Safiul Islam & S.M. Abdullah Al Kafi. (2024) Advances and significances of gold nanoparticles in cancer treatment: A comprehensive review. Results in Chemistry 8, pages 101559.
Crossref
Wenxi Wang, Jiayan Lu, Anyin Dai, Longyu Shang, Mengjiao Chen & Lina Chen. (2024) Enhanced dissolution of curcumin-resorcinol cocrystal by the inhibition effect of HPMCAS on solution-mediated phase transformation. Journal of Molecular Liquids 403, pages 124802.
Crossref
Nasa Sakamoto, Kenichi Miyata & Toshiro Fukami. (2023) Quabodepistat (OPC-167832), a Novel Antituberculosis Drug Candidate: Enhancing Oral Bioavailability via Cocrystallization and Mechanistic Analysis of Bioavailability in Two Cocrystals. Molecular Pharmaceutics 21:1, pages 358-369.
Crossref
Shilan Lin, Zhijie Chen, Shaoguang Li, Bing Chen, Youjia Wu, Yanjie Zheng, Jianyong Huang, Yan Chen, Xinhua Lin & Hong Yao. (2024) Anti-tumor effect and mechanism of the total biflavonoid extract from S doederleinii on human cervical cancer cells in vitro and in vivo. Heliyon 10:2, pages e24778.
Crossref
Quanyong Wu, Boya Ouyang, Mohamed Farag, Miguel A. Prieto, Hui Cao & Jesus Simal-Gandara. 2023. Handbook of Dietary Flavonoids. Handbook of Dietary Flavonoids 1 32 .
Debadatta Mohapatra, Dulla Naveen Kumar, Singh Shreya, Vivek Pandey, Pawan K. Dubey, Ashish Kumar Agrawal & Alakh N Sahu. (2023) Quality by design–based development and optimization of fourth-generation ternary solid dispersion of standardized Piper longum extract for melanoma therapy. Drug Delivery and Translational Research 13:12, pages 3094-3131.
Crossref
Kiran Dudhat, Monika Bhalodiya, Ashvin Dudhrejiya, Sunny Shah, Ramesh Parmar, Lalji Baldaniya & Mori Dhaval. (2023) Application of Amorphous Solid Dispersion Technology for Improving the Physicochemical Properties, Saturation Solubility, and In Vitro Dissolution of Withania somnifera Methanolic Root Powder Extract. Journal of Pharmaceutical Innovation 18:3, pages 1338-1349.
Crossref
Arif Budiman, Annisa Luthfiyah Handini, Mutia Nur Muslimah, Neng Vera Nurani, Eli Laelasari, Insan Sunan Kurniawansyah & Diah Lia Aulifa. (2023) Amorphous Solid Dispersion as Drug Delivery Vehicles in Cancer. Polymers 15:16, pages 3380.
Crossref
Chie Aoki‐Utsubo, Puguh Indrasetiawan, Kento Fukano, Masamichi Muramatsu, Nina Artanti, Muhammad Hanafi, Hak Hotta & Masanori Kameoka. (2023) Amentoflavone inhibits hepatitis B virus infection via the suppression of preS1 binding to host cells. Microbiology and Immunology 67:6, pages 281-292.
Crossref
Hardeep Singh Tuli, Hemant Joshi, Kanupriya Vashishth, Seema Ramniwas, Mehmet Varol, Manoj Kumar, Isha Rani, Vibha Rani & Katrin Sak. (2023) Chemopreventive mechanisms of amentoflavone: recent trends and advancements. Naunyn-Schmiedeberg's Archives of Pharmacology 396:5, pages 865-876.
Crossref
Mengdie Ren, Sihui Li, Qiong Gao, Lei Qiao, Qianping Cao, Ze Yang, Chaoqiang Chen, Yongmei Jiang, Gang Wang & Shaobin Fu. (2023) Advances in the Anti-Tumor Activity of Biflavonoids in Selaginella. International Journal of Molecular Sciences 24:9, pages 7731.
Crossref
Fatemeh Omidfar, Fatemeh Gheybi, Javid Davoodi, Mostafa Amirinejad & Ali Badiee. (2022) Nanophytosomes of hesperidin and of hesperetin: Preparation, characterization, and in vivo evaluation. Biotechnology and Applied Biochemistry 70:2, pages 846-856.
Crossref
Asmerom O. Weldeab, John-David McElderry & Yiqing Lin. (2022) The Effect of In-Situ-Generated Moisture on Disproportionation of Pharmaceutical Salt. Molecular Pharmaceutics 20:1, pages 561-571.
Crossref
Khushbu Wadhwa, Hardeep Kaur, Neha Kapoor, Soma M. Ghorai, Renu Gupta & Arunima Sahgal. (2023) A systematic review on antimicrobial activities of green synthesised Selaginella silver nanoparticles . Expert Reviews in Molecular Medicine 25.
Crossref
Neelam SharmaNeha KanojiaSukhbir SinghAnita Antil. (2022) Application of Central Composite Design for Formulation and Optimization of Solid Dispersion for Dissolution Rate Enhancement of BCS Class II Drug. Research Journal of Pharmacy and Technology, pages 5659-5664.
Crossref
Ruba Malkawi, Walla I. Malkawi, Yahia Al-Mahmoud & Jawad Tawalbeh. (2022) Current Trends on Solid Dispersions: Past, Present, and Future. Advances in Pharmacological and Pharmaceutical Sciences 2022, pages 1-17.
Crossref
Lina Zhou, Rong Wang, Jingjin Wang, Ke Zhao, Tao Zhang, Xiaolong Hu, Fei Xiong, Xiaoqi Zhang, Wencai Ye, Xinhong Shi & Hao Wang. (2022) Characterization, solubility and stability of amentoflavone polymorphs. Journal of Molecular Structure 1262, pages 133101.
Crossref
Rajiv Bajracharya, Jae Geun Song, Sang Hoon Lee, Seong Hoon Jeong & Hyo-Kyung Han. (2022) Enhanced Oral Bioavailability of MT-102, a New Anti-inflammatory Agent, via a Ternary Solid Dispersion Formulation. Pharmaceutics 14:7, pages 1510.
Crossref
Yu Fang, Hangdi Niu, Yanyan Guo, Yi Bao & Yuhua Ma. (2022) Preparation, optimization and bioavailability studies of the bergenin solid dispersion pellets. Journal of Drug Delivery Science and Technology 73, pages 103379.
Crossref
Kaushika Patel, Shreeraj Shah & Jaymin Patel. (2022) Solid dispersion technology as a formulation strategy for the fabrication of modified release dosage forms: A comprehensive review. DARU Journal of Pharmaceutical Sciences 30:1, pages 165-189.
Crossref
Mariana Colombo, Luana Roberta Michels, Helder Ferreira Teixeira & Letícia Scherer Koester. (2021) Flavonoid delivery by solid dispersion: a systematic review. Phytochemistry Reviews 21:3, pages 783-808.
Crossref
Bing Chen, Dafen Xu, Zhijun Li, Yafei Jing, Luping Lin, Shaoguang Li, Liying Huang, Xiuwang Huang, Ailin Liu, Xinhua Lin & Hong Yao. (2022) Tissue Distribution, Excretion, and Interaction With Human Serum Albumin of Total Bioflavonoid Extract From Selaginella doederleinii. Frontiers in Pharmacology 13.
Crossref
丹 黎. (2022) Research Progress on Chemical Composition, Pharmacological Action of Selaginella doederleininii. Hans Journal of Medicinal Chemistry 10:02, pages 153-171.
Crossref
Yang Xie, Xi Zhou, Jing Li, Xiao-chang Yao, Wan-li Liu, Ping-sheng Xu & Gui-shan Tan. (2022) Cytotoxic effects of the biflavonoids isolated from Selaginella trichoclada on MCF-7 cells and its potential mechanism. Bioorganic & Medicinal Chemistry Letters 56, pages 128486.
Crossref
Sathish Dharani, Khaldia Sediri, Phillip Cook, Rajendran Arunagiri, Mansoor A. Khan & Ziyaur Rahman. (2021) Preparation and Characterization of Stable Amorphous Glassy Solution of BCS II and IV Drugs. AAPS PharmSciTech 23:1.
Crossref
Xifeng Xiong, Nan Tang, Xudong Lai, Jinli Zhang, Weilun Wen, Xiaojian Li, Aiguo Li, Yanhua Wu & Zhihe Liu. (2021) Insights Into Amentoflavone: A Natural Multifunctional Biflavonoid. Frontiers in Pharmacology 12.
Crossref
Rohitesh Kumar, Jitka Viktorova, Bara Krizkovska, Jan Lipov & Tomas Ruml. (2021) Structural diversity and biological activities of secondary metabolites isolated from the genus Selaginella. Phytochemistry Reviews 20:6, pages 1209-1243.
Crossref
Bing Chen, Hongbin Luo, Weiying Chen, Qishu Huang, Kaifan Zheng, Dafen Xu, Shaoguang Li, Ailin Liu, Liying Huang, Yanjie Zheng, Xinhua Lin & Hong Yao. (2021) Pharmacokinetics, Tissue Distribution, and Human Serum Albumin Binding Properties of Delicaflavone, a Novel Anti-Tumor Candidate. Frontiers in Pharmacology 12.
Crossref
Jean-François Goossens, Laurence Goossens & Christian Bailly. (2021) Hinokiflavone and Related C–O–C-Type Biflavonoids as Anti-cancer Compounds: Properties and Mechanism of Action. Natural Products and Bioprospecting 11:4, pages 365-377.
Crossref
José C.J.M.D.S. Menezes & Marc F. Diederich. (2021) Bioactivity of natural biflavonoids in metabolism-related disease and cancer therapies. Pharmacological Research 167, pages 105525.
Crossref
Zimbili Mkhize, Pule Silent Seboletswe, Hugues Kamdem Paumo, Pone Kamdem Boniface & Lebogang Maureen Katata-Seru. (2021) Enhanced Antioxidant Efficacy of Nano-Encapsulated Protorhus Longifolia Methanol Extract Stabilized with Eudragit . International Journal of Nanoscience 20:02, pages 2150017.
Crossref
Yasmin Silva Rizk, Sandy Santos-Pereira, Luiza Gervazoni, Daiana de Jesus Hardoim, Flávia de Oliveira Cardoso, Celeste da Silva Freitas de Souza, Marcelo Pelajo-Machado, Carlos Alexandre Carollo, Carla Cardozo Pinto de Arruda, Elmo Eduardo Almeida-Amaral, Tânia Zaverucha-do-Valle & Kátia da Silva Calabrese. (2021) Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms. Frontiers in Cellular and Infection Microbiology 11.
Crossref
Verônica da Silva Oliveira, Elen Diana Dantas, Anna Thereza de Sousa Queiroz, Johny Wysllas de Freitas Oliveira, Marcelo de Sousa da Silva, Patricia Garcia Ferreira, Fernando de Carvalho da Siva, Vitor Francisco Ferreira & Ádley Antonini Neves de Lima. (2020) Novel Solid Dispersions of Naphthoquinone Using Different Polymers for Improvement of Antichagasic Activity. Pharmaceutics 12:12, pages 1136.
Crossref
Verônica da Silva Oliveira, Amanda Silva de Almeida, Ingrid da Silva Albuquerque, Fernanda Ílary Costa Duarte, Bárbara Cristina Silva Holanda Queiroz, Attilio Converti & Ádley Antonini Neves de Lima. (2020) Therapeutic Applications of Solid Dispersions for Drugs and New Molecules: In Vitro and In Vivo Activities. Pharmaceutics 12:10, pages 933.
Crossref
yu fang, hangdi niu, yanyan guo, yi bao & Yuhua Ma. (2022) Preparation, Optimization and Bioavailability Studies Of The Bergenin Solid Dispersion Pellets. SSRN Electronic Journal.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.