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Drug Delivery Volume 27, 2020 - Issue 1
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Original Paper

Incorporation of ion exchange functionalized-montmorillonite into solid lipid nanoparticles with low irritation enhances drug bioavailability for glaucoma treatment

Shuo Liua College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
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Xinyue Hana College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
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Hanyu Liua College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
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Yawen Zhaoa College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
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Huamei Lia College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
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Ilva D. Rupenthalb Buchanan Ocular Therapeutics Unit, Department of Ophthalmology, New Zealand National Eye Center, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New ZealandView further author information
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Zhufen Lvc Guangdong Engineering and Technology Research Center of Topical Precise Drug Delivery System, College of Pharmacy, Department of Pharmaceutics, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
,
Yanzhong Chenc Guangdong Engineering and Technology Research Center of Topical Precise Drug Delivery System, College of Pharmacy, Department of Pharmaceutics, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
,
Fan Yangc Guangdong Engineering and Technology Research Center of Topical Precise Drug Delivery System, College of Pharmacy, Department of Pharmaceutics, Guangdong Pharmaceutical University, Guangzhou, PR ChinaView further author information
,
Qineng Pingd College of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaView further author information
,
Yufang Pana College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, PR ChinaCorrespondence[email protected]
View further author information
&
Dongzhi Houa College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, PR ChinaCorrespondence[email protected]
View further author information
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Pages 652-661 | Received 12 Mar 2020, Accepted 14 Apr 2020, Published online: 29 Apr 2020

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Huamei Li, Fuda Dai, Hanyu Liu, Qi Tao, Jie Hu, Yangrong Zhang, Zhenping Xiao, Ilva D. Rupenthal, Huihui Li, Fan Yang, Wei Li, Huaqing Lin & Dongzhi Hou. (2023) Physicochemical properties and micro-interaction between micro-nanoparticles and anterior corneal multilayer biological interface film for improving drug delivery efficacy: the transformation of tear film turnover mode. Drug Delivery 30:1.
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Zhen Liang, Zhen Zhang, Jingjing Yang, Ping Lu, Tianyang Zhou, Jingguo Li & Junjie Zhang. (2021) Assessment to the Antifungal Effects in vitro and the Ocular Pharmacokinetics of Solid-Lipid Nanoparticle in Rabbits. International Journal of Nanomedicine 16, pages 7847-7857.
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Hanyu Liu, Xinyue Han, Huamei Li, Qi Tao, Jie Hu, Shuo Liu, Huaixin Liu, Jun Zhou, Wei Li, Fan Yang, Qineng Ping, Shijie Wei, Hongmei Liu, Huaqing Lin & Dongzhi Hou. (2021) Wettability and contact angle affect precorneal retention and pharmacodynamic behavior of microspheres. Drug Delivery 28:1, pages 2011-2023.
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Adéla Klézlová, Petr Bulíř, Andrea Klápšťová, Magdaléna Netuková, Kateřina Šenková, Jana Horáková & Pavel Studený. (2024) Novel Biomaterials in Glaucoma Treatment. Biomedicines 12:4, pages 813.
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Zhen Liang, Zhen Zhang, Ping Lu, Jingjing Yang, Lei Han, Susu Liu, Tianyang Zhou, Jingguo Li & Junjie Zhang. (2023) The effect of charges on the corneal penetration of solid lipid nanoparticles loaded Econazole after topical administration in rabbits. European Journal of Pharmaceutical Sciences 187, pages 106494.
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Jing Zhang, Lan Wang, Jianghong Li, Yuhong Guo, Jinxin Chen, Xudong Li, Man Cheng, Bo Feng & Ying Zhang. (2023) Preparation and intraocular evaluation of cetirizine hydrochloride ophthalmic liposomes and a liposome in situ gel. MedComm – Biomaterials and Applications 2:2.
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Jia Liu, Shubin Yang, Laien Zhao, Feng Jiang, Jianchao Sun, Shengjun Peng, Ruikang Zhao, Yanmei Huang, Xiaoxuan Fu, Rongrui Luo, Yu Jiang, Zelin Li, Nan Wang, Tengzheng Fang & Zhuhong Zhang. (2023) ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo. Particle and Fibre Toxicology 20:1.
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Kevin Y. Wu, Said Ashkar, Shrieda Jain, Michael Marchand & Simon D. Tran. (2023) Breaking Barriers in Eye Treatment: Polymeric Nano-Based Drug-Delivery System for Anterior Segment Diseases and Glaucoma. Polymers 15:6, pages 1373.
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Garima Madhariya, Shubha Diwan, Ravishankar Chauhan, Nagendra Kumar Chandrawanshi & Pramod Kumar Mahish. 2023. Handbook of Biomolecules. Handbook of Biomolecules 397 418 .
Biswarup Das, Amit Kumar Nayak & Subrata Mallick. (2022) Lipid-based nanocarriers for ocular drug delivery: An updated review. Journal of Drug Delivery Science and Technology 76, pages 103780.
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Zhimin Tang, Xianqun Fan, Yu Chen & Ping Gu. (2022) Ocular Nanomedicine. Advanced Science 9:15.
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Liangbo Chen, Feng Wu, Yan Pang, Dan Yan, Siyi Zhang, Fangjie Chen, Nianxuan Wu, Danni Gong, Jinyao Liu, Yao Fu & Xianqun Fan. (2021) Therapeutic nanocoating of ocular surface. Nano Today 41, pages 101309.
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Kui Xue, Lu-Xian Liang, Shen-Cong Cheng, Han-Peng Liu, Lan-Yue Cui, Rong-Chang Zeng, Shuo-Qi Li & Zhen-Lin Wang. (2021) Corrosion resistance, antibacterial activity and drug release of ciprofloxacin-loaded micro-arc oxidation/silane coating on magnesium alloy AZ31. Progress in Organic Coatings 158, pages 106357.
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Yue Ding, Seong H. Chow, Jinying Chen, Anton P. Le Brun, Chun-Ming Wu, Anthony P. Duff, Yajun Wang, Jiangning Song, Jiang-Hui Wang, Vickie H.Y. Wong, Da Zhao, Tomoharu Nishimura, Tzong-Hsien Lee, Charlotte E. Conn, Hsien-Yi Hsu, Bang V. Bui, Guei-Sheung Liu & Hsin-Hui Shen. (2021) Targeted delivery of LM22A-4 by cubosomes protects retinal ganglion cells in an experimental glaucoma model. Acta Biomaterialia 126, pages 433-444.
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Seungjin Yu, Huiyan Piao, N. Sanoj Rejinold, Geunwoo Jin, Goeun Choi & Jin-Ho Choy. (2021) Niclosamide–Clay Intercalate Coated with Nonionic Polymer for Enhanced Bioavailability toward COVID-19 Treatment. Polymers 13:7, pages 1044.
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