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Research Articles

Development and optimization of curcumin analog nano-bilosomes using 21.31 full factorial design for anti-tumor profiles improvement in human hepatocellular carcinoma: in-vitro evaluation, in-vivo safety assay

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Pages 714-727 | Received 11 Jan 2022, Accepted 14 Feb 2022, Published online: 04 Mar 2022

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Hemlata Kaurav, Deepak N Kapoor & Navneet Kumar Upadhyay. (2023) Bilosomes in Brain Drug Delivery. Therapeutic Delivery 14:8, pages 473-475.
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Jianfeng Zhou, Pu Wang, Deng-Guang Yu & Yuanjie Zhu. (2023) Biphasic drug release from electrospun structures. Expert Opinion on Drug Delivery 20:5, pages 621-640.
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Nabil K Alruwaili, Ameeduzzafar Zafar, Omar Awad Alsaidan, Mohd Yasir, Ehab M. Mostafa, Sultan F. Alnomasy, Alenazy Rawaf, Ali Alquraini & Fadhel A. Alomar. (2022) Development of surface modified bilosomes for the oral delivery of quercetin: optimization, characterization in-vitro antioxidant, antimicrobial, and cytotoxicity study. Drug Delivery 29:1, pages 3035-3050.
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Articles from other publishers (22)

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Heba Abd-El-Azim, Haidy Abbas, Nesrine El Sayed, Mohamed R. Mousa, Hadil M. Elbardisy & Mariam Zewail. (2024) Hypericin emulsomes combined with hollow microneedles as a non-invasive photodynamic platform for rheumatoid arthritis treatment. International Journal of Pharmaceutics 653, pages 123876.
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Sarah A. Sideek, Hala B. El-Nassan, Ahmed R. Fares, Nermeen A. Elkasabgy & Aliaa N. ElMeshad. (2024) Cross-Linked Alginate Dialdehyde/Chitosan Hydrogel Encompassing Curcumin-Loaded Bilosomes for Enhanced Wound Healing Activity. Pharmaceutics 16:1, pages 90.
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Abdulmohsin J. Alamoudi, Shaimaa M. Badr-Eldin, Osama A.A. Ahmed, Usama A. Fahmy, Serag Eldin I. Elbehairi, Mohammad Y. Alfaifi, Hani Z. Asfour, Gamal A. Mohamed, Sabrin R.M. Ibrahim, Ashraf B. Abdel-Naim & Hossam M. Abdallah. (2023) Optimized bilosome-based nanoparticles enhance cytotoxic and pro-apoptotic activity of costunolide in LS174T colon cancer cells. Biomedicine & Pharmacotherapy 168, pages 115757.
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Atefeh Naseri, Somayeh Taymouri, Ali Hosseini Sharifabadi & Jaleh Varshosaz. (2023) Chrysin loaded bilosomes improve the hepatoprotective effects of chrysin against CCl4 induced hepatotoxicity in mice. Journal of Biomaterials Applications 38:4, pages 509-526.
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Tarek M. Ibrahim. (2023) Exploitation of transdermal nanobilosomal gel platforms for ameliorating anti-diabetic activity of empagliflozin following I-optimal design. Journal of Drug Delivery Science and Technology 84, pages 104455.
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Ranjit K. Harwansh, Mukul Yadav, Rohitas Deshmukh & Akhlaquer Rahman. (2023) Recent Insights into Nanoparticulate Carrier Systems of Curcumin and its Clinical Perspective in the Management of Various Health Issues. Current Pharmaceutical Design 29:18, pages 1421-1440.
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Raghda Abdel-moneum & Rania S. Abdel-Rashid. (2023) Bile salt stabilized nanovesicles as a promising drug delivery technology: A general overview and future perspectives. Journal of Drug Delivery Science and Technology 79, pages 104057.
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Mariam Zewail, Passent M. E. Gaafar, Nancy Abdel Hamid Abou Youssef, Merhan E. Ali, Mai F. Ragab, Miranda F. Kamal, Mohamed H. Noureldin & Haidy Abbas. (2022) Novel Siprulina platensis Bilosomes for Combating UVB Induced Skin Damage. Pharmaceuticals 16:1, pages 36.
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Zahra Farzaneh & Maryam Farzaneh. (2022) Herbal Medicine-derived Compounds for the Prevention and Treatment of Hepatocellular Carcinoma. Current Cancer Therapy Reviews 18:4, pages 230-238.
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WeiLu Jia, YingHui Han, XinYu Mao, WenJing Xu & YeWei Zhang. (2022) Nanotechnology strategies for hepatocellular carcinoma diagnosis and treatment. RSC Advances 12:48, pages 31068-31082.
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Tamer M. Mahmoud, Mohamed M. Nafady, Hanan O. Farouk, Dina M. Mahmoud, Yasmin M. Ahmed, Randa Mohammed Zaki & Doaa S. Hamad. (2022) Novel Bile Salt Stabilized Vesicles-Mediated Effective Topical Delivery of Diclofenac Sodium: A New Therapeutic Approach for Pain and Inflammation. Pharmaceuticals 15:9, pages 1106.
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Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Usama A. Fahmy, Osama A. A. Ahmed, Nabil A. Alhakamy, Omar D. Al-hejaili, Alhanoof A. Alhassan, Ghadeer A. Ammari, Shouq I. Alhazmi, Raghad M. Alawadi, Rana Bakhaidar, Abdulmohsen J. Alamoudi, Thikryat Neamatallah & Singkome Tima. (2022) Optimized Apamin-Mediated Nano-Lipidic Carrier Potentially Enhances the Cytotoxicity of Ellagic Acid against Human Breast Cancer Cells. International Journal of Molecular Sciences 23:16, pages 9440.
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Liang Wang, Shixia Zhu, Chunpeng Zou, Hongju Kou, Maosheng Xu & Jie Li. (2022) Preparation and evaluation of the anti-cancer properties of RGD-modified curcumin-loaded chitosan/perfluorohexane nanocapsules in vitro. Heliyon 8:7, pages e09931.
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Mengyuan Zhao, Yun Fu, Lili Liu, Yong Hou, Mei Shi, Hao Zhou & Guoliang Zhang. (2022) Identification of Key Drug Targets and Molecular Mechanisms of Curcumae Rhizoma Acting on HBV-Related HCC: Weighted Correlation Network and Network Pharmacological Analyses. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-15.
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