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Research Articles

Surface-tailoring of emulsomes for boosting brain delivery of vinpocetine via intranasal route: in vitro optimization and in vivo pharmacokinetic assessment

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Pages 2671-2684 | Received 31 May 2022, Accepted 01 Aug 2022, Published online: 16 Aug 2022

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Elena García-Gareta, Alejandro Calderón-Villalba, Pilar Alamán-Díez, Carlos Gracia Costa, Pedro Enrique Guerrero, Carlota Mur, Ana Rueda Flores, Nerea Olivera Jurjo, Patricia Sancho, María Ángeles Pérez & José Manuel García-Aznar. (2024) Physico-chemical characterization of the tumour microenvironment of pancreatic ductal adenocarcinoma. European Journal of Cell Biology 103:2, pages 151396.
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Zhang Chao Dong, Yang Shi, Li Juan Liu, Ting Ting Feng, Ying Zhou & Bo Wen Pan. (2024) Synthesis and pharmacological activity of vinpocetine derivatives. RSC Advances 14:12, pages 7981-7991.
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Sumaia Abdulbari Ahmed Ali Hard, H.N. Shivakumar & Moqbel Ali Moqbel Redhwan. (2023) Development and optimization of in-situ gel containing chitosan nanoparticles for possible nose-to-brain delivery of vinpocetine. International Journal of Biological Macromolecules 253, pages 127217.
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Shivam Singh, Kunal Khurana, Shikha Baghel Chauhan & Indu Singh. (2023) Emulsomes: new lipidic carriers for drug delivery with special mention to brain drug transport. Future Journal of Pharmaceutical Sciences 9:1.
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Marwa Hasanein Asfour & Abeer A.A. Salama. (2023) Coating with tripolyphosphate-crosslinked chitosan as a novel approach for enhanced stability of emulsomes following oral administration: Rutin as a model drug with improved anti-hyperlipidemic effect in rats. International Journal of Pharmaceutics 644, pages 123314.
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Angela Bonaccorso, Anna Privitera, Margherita Grasso, Sonya Salamone, Claudia Carbone, Rosario Pignatello, Teresa Musumeci, Filippo Caraci & Giuseppe Caruso. (2023) The Therapeutic Potential of Novel Carnosine Formulations: Perspectives for Drug Development. Pharmaceuticals 16:6, pages 778.
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Helen Elizabeth Ritchie, Jaimie W. Polson, Andrea Xia & William Webster. (2023) Effect of vinpocetine on embryonic heart rate in vitro. Current Research in Toxicology 5, pages 100125.
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Waleed S. Alharbi, Rawan H. Hareeri, Mohammed Bazuhair, Mohamed A. Alfaleh, Nabil A. Alhakamy, Usama A. Fahmy, Abdullah A. Alamoudi, Shaimaa M. Badr-Eldin, Osama A. Ahmed, Shareefa A. AlGhamdi & Marianne J. Naguib. (2022) Spanlastics as a Potential Platform for Enhancing the Brain Delivery of Flibanserin: In Vitro Response-Surface Optimization and In Vivo Pharmacokinetics Assessment. Pharmaceutics 14:12, pages 2627.
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