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Journal of Liquid Chromatography & Related Technologies Volume 30, 2007 - Issue 19
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Original Articles

Monitoring of Impurity Level of Valsartan and Hydrochlorothiazide Employing an RP–HPLC Gradient Mode

Darko Ivanović Faculty of Pharmacy, Department of Drug Analysis, Belgrade, Serbia
,
Anđelija Malenović Faculty of Pharmacy, Department of Drug Analysis, Belgrade, Serbia
,
Biljana Jančić Faculty of Pharmacy, Department of Drug Analysis, Belgrade, Serbia
,
Prof. Dr. Mirjana Medenica Faculty of Pharmacy, Department of Physical Chemistry, Belgrade, SerbiaCorrespondence[email protected]
&
Marija Mašković Medicines and Medical Devices Agency of Serbia, Serbia
Pages 2879-2890 | Received 05 Dec 2006, Accepted 01 Jun 2007, Published online: 09 Nov 2007

Citations (18)

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Megha N. Salunkhe, Snehal D. Gite & Ramanlal N. Kachave. (2017) Recent trends in impurity profiling and forced degradation of antihypertensive drugs. Journal of Liquid Chromatography & Related Technologies 40:16, pages 813-831.
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RominaM. Bianchini, PatriciaM. Castellano & TeodoroS. Kaufman. (2012) STRESS TESTING OF VALSARTAN. DEVELOPMENT AND VALIDATION OF A HIGH PERFORMANCE LIQUID CHROMATOGRAPHY STABILITY-INDICATING ASSAY. Journal of Liquid Chromatography & Related Technologies 35:8, pages 1053-1069.
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RashaA. Shaalan & TarekS. Belal. (2012) GRADIENT HPLC-DAD DETERMINATION OF THE ANTIHYPERTENSIVE MIXTURE OF AMLODIPINE BESYLATE, VALSARTAN, AND HYDROCHLOROTHIAZIDE IN COMBINED PHARMACEUTICAL TABLETS. Journal of Liquid Chromatography & Related Technologies 35:2, pages 215-230.
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SilvanaE. Vignaduzzo, PatriciaM. Castellano & TeodoroS. Kaufman. (2011) DEVELOPMENT AND VALIDATION OF AN HPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF AMLODIPINE, HYDROCHLOROTHIAZIDE, AND VALSARTAN IN TABLETS OF THEIR NOVEL TRIPLE COMBINATION AND BINARY PHARMACEUTICAL ASSOCIATIONS. Journal of Liquid Chromatography & Related Technologies 34:19, pages 2383-2395.
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NesrinK. Ramadan, HebaM. Mohamed & AzzaA. Moustafa. (2010) Rapid and Highly Sensitive HPLC and TLC Methods for Quantitation of Amlodipine Besilate and Valsartan in Bulk Powder and in Pharmaceutical Dosage Forms and in Human Plasma. Analytical Letters 43:4, pages 570-581.
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Articles from other publishers (13)

Timon Kurzawa, Salim Fazzani, René Tempel, Hannes Helmboldt, Christian Bleschke, Andreas Kohlmann & Adelheid Hagenbach. (2023) Characterization of hitherto unknown Valsartan photodegradation impurities. Journal of Molecular Structure 1275, pages 134599.
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Eman A. Bahgat, Hanaa Saleh, Alaa Reda & Michael Gamal Fawzy. (2022) Development and validation of eco-friendly micellar organic solvent-free HPLC method for the simultaneous determination of some antihypertensive combinations. Microchemical Journal 181, pages 107740.
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Magda M. Ayad, Mervat M. Hosny, Adel Ehab Ibrahim, Omar M. El-Abassy & Fathalla F. Belal. (2020) Development and validation of eco-friendly micellar HPLC method for the simultaneous determination of hydrochlorothiazide and valsartan in bulk powder and pharmaceutical dosage forms. Journal of the Iranian Chemical Society 17:7, pages 1725-1730.
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Ibrahim A Naguib, Eglal A Abdelaleem, Fatma F Abdallah & Aml A Emam. (2020) Development and Validation of Two Chromatographic Methods for Simultaneous Determination and Quantification of Amiloride Hydrochloride, Hydrochlorothiazide, and Their Related Substances, in Pure and Tablet Forms. Journal of AOAC INTERNATIONAL 103:3, pages 747-754.
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B. Venkateswara Rao, S. Vidyadhara & V. Basaveswara Rao. (2017) A NOVEL STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE IN BULK AND PHARMACEUTICAL FORMULATIONS. INDIAN DRUGS 54:08, pages 54-61.
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Rasha A. Shaalan, Tarek S. Belal, Fawzy A. El Yazbi & Sohila M. Elonsy. (2017) Validated stability-indicating HPLC-DAD method of analysis for the antihypertensive triple mixture of amlodipine besylate, valsartan and hydrochlorothiazide in their tablets. Arabian Journal of Chemistry 10, pages S1381-S1394.
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Jiří Vojta, Aleš Jedlička, Pavel Coufal & Lucie Janečková. (2015) A new, rapid, stability-indicating UPLC method for separation and determination of impurities in amlodipine besylate, valsartan and hydrochlorothiazide in their combined tablet dosage form. Journal of Pharmaceutical and Biomedical Analysis 109, pages 36-44.
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Febry Ardiana, Suciati & Gunawan Indrayanto. 2015. 431 493 .
Izabela Muszalska, Agnieszka Sobczak, Agnieszka Dołhań & Anna Jelińska. (2014) Analysis of Sartans: A Review. Journal of Pharmaceutical Sciences 103:1, pages 2-28.
Crossref
Romina M. Bianchini, Patricia M. Castellano & Teodoro S. Kaufman. (2011) Characterization of two new potential impurities of Valsartan obtained under photodegradation stress condition. Journal of Pharmaceutical and Biomedical Analysis 56:1, pages 16-22.
Crossref
Bahia Moussa, Marwa Mohamed & Nadia Youssef. (2011) Simultaneous densitometric TLC analysis of olmesartan medoxomil and hydrochlorothiazide in the tablet dosage form. Journal of Planar Chromatography – Modern TLC 24:1, pages 35-39.
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Nashwah Gadallah Mohamed. (2011) Simultaneous Determination of Amlodipine and Valsartan. Analytical Chemistry Insights 6, pages ACI.S7282.
Crossref
Rasha A. Shaalan & Tarek S. Belal. (2010) Simultaneous spectrofluorimetric determination of amlodipine besylate and valsartan in their combined tablets. Drug Testing and Analysis 2:10, pages 489-493.
Crossref

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