310
Views
17
CrossRef citations to date
0
Altmetric
Research Article

Behavior of Moisture Gain and Equilibrium Moisture Contents (EMC) of Various Drug Substances and Correlation with Compendial Information on Hygroscopicity and Loss on Drying

, , & , Ph.D.
Pages 489-497 | Received 21 Feb 2005, Accepted 20 Apr 2005, Published online: 07 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Mary K. Chaves, Ron C. Kelly, Jacqueline E. Milne & Susan E. Burke. (2022) Data-driven approach to mitigate quality impact of hygroscopic pharmaceutical raw materials throughout the supply chain. Pharmaceutical Development and Technology 27:5, pages 511-524.
Read now
Chun-Ning Mao, Kotiba A. Malek & Akua Asa-Awuku. (2021) Hygroscopicity and the water-polymer interaction parameter of nano-sized biodegradable hydrophilic substances. Aerosol Science and Technology 55:10, pages 1115-1124.
Read now
Vasudha Murikipudi, Piyush Gupta & Vaibhav Sihorkar. (2013) Efficient throughput method for hygroscopicity classification of active and inactive pharmaceutical ingredients by water vapor sorption analysis. Pharmaceutical Development and Technology 18:2, pages 348-358.
Read now
Anikó Szepes, Piroska Szabó-Révész & Mandy Mohnicke. (2007) Water Sorption Behavior and Swelling Characteristics of Starches Subjected to Dielectric Heating. Pharmaceutical Development and Technology 12:6, pages 555-561.
Read now

Articles from other publishers (13)

Chao Peng, Lanxiadi Chen & Mingjin Tang. (2022) A database for deliquescence and efflorescence relative humidities of compounds with atmospheric relevance. Fundamental Research 2:4, pages 578-587.
Crossref
Qi Zhang, Baolin Huang, Hongjiao Xue, Zimin Lin, Jie Zhao & Zheng Cai. (2021) Preparation, Characterization, and Selection of Optimal Forms of (S)-Carvedilol Salts for the Development of Extended-Release Formulation. Molecular Pharmaceutics 18:6, pages 2298-2310.
Crossref
Sagar Narala, Dinesh Nyavanandi, Priyanka Srinivasan, Preethi Mandati, Suresh Bandari & Michael A. Repka. (2021) Pharmaceutical Co-crystals, Salts, and Co-amorphous Systems: A novel opportunity of hot-melt extrusion. Journal of Drug Delivery Science and Technology 61, pages 102209.
Crossref
Linlin Chen, Yu Qin, Jing Cheng, Yi Cheng, Zhixiang Lu, Xiaolan Liu, Shaoxiong Yang, Shuhan Lu, Liyan Zheng & Qiue Cao. (2020) A biocompatible PAA-Cu-MOP hydrogel for wound healing. RSC Advances 10:59, pages 36212-36218.
Crossref
Yi Hu, Cuiping Jiang, Bin Li, Lijing Zhou, Renjie Xu, Yujie Guo, Yan Cao, Guosheng Cao & Shan Lu. (2020) A novel lurasidone hydrochloride–shikimic acid co-amorphous system formed by hydrogen-bonding interaction with the retained pH-dependent solubility behavior. CrystEngComm 22:35, pages 5841-5853.
Crossref
Okky Dwichandra Putra & Hidehiro Uekusa. 2020. Advances in Organic Crystal Chemistry. Advances in Organic Crystal Chemistry 153 184 .
Deepak Gupta, Deepak Bhatia, Vivek Dave, Vijaykumar Sutariya & Sheeba Varghese Gupta. (2018) Salts of Therapeutic Agents: Chemical, Physicochemical, and Biological Considerations. Molecules 23:7, pages 1719.
Crossref
Jihye Lee, Dongwook Kim, Jaehyeon Park, Eunice EunKyeong Kim, Myoung Soo Lah & Aeri Kim. (2017) Pseudopolymorphs of LB30870, a Direct Thrombin Inhibitor: One-Dimensional Solvent Channel Structures Explain Reversible Hydration/Dehydration. Crystal Growth & Design 18:1, pages 95-104.
Crossref
M.Y. Gokhale & R.V. Mantri. 2017. Developing Solid Oral Dosage Forms. Developing Solid Oral Dosage Forms 85 112 .
Radhika Sharma, Sunil Kamboj, Rajneet Khurana, Gursharan Singh & Vikas Rana. (2015) Physicochemical and functional performance of pectin extracted by QbD approach from Tamarindus indica L. pulp. Carbohydrate Polymers 134, pages 364-374.
Crossref
Hywel D. Williams, Natalie L. Trevaskis, Susan A. Charman, Ravi M. Shanker, William N. Charman, Colin W. Pouton & Christopher J. H. Porter. (2013) Strategies to Address Low Drug Solubility in Discovery and Development. Pharmacological Reviews 65:1, pages 315-499.
Crossref
Saranjit Singh, Amrit Paudel, Gaurav Bedse, Rhishikesh Thakare & Vijay Kumar. 2010. Pharmaceutical Stability Testing to Support Global Markets. Pharmaceutical Stability Testing to Support Global Markets 37 44 .
Ann W. Newman, Susan M. Reutzel‐Edens & George Zografi. (2008) Characterization of the “hygroscopic” properties of active pharmaceutical ingredients. Journal of Pharmaceutical Sciences 97:3, pages 1047-1059.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.