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Expert Opinion on Therapeutic Patents Volume 29, 2019 - Issue 10: Glaucoma and macular degeneration
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Review

Rho-kinase inhibitors in the management of glaucoma

Emanuela BerrinoNEUROFARBA Dept., Sezione di Scienze Farmaceutiche, University of Florence, Sesto Fiorentino (Florence), ItalyCorrespondence[email protected]
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Claudiu T SupuranNEUROFARBA Dept., Sezione di Scienze Farmaceutiche, University of Florence, Sesto Fiorentino (Florence), ItalyORCID Iconhttps://orcid.org/0000-0003-4262-0323View further author information
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Pages 817-827 | Received 21 Aug 2019, Accepted 18 Sep 2019, Published online: 01 Oct 2019

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Samdani Ansar & Umashankar Vetrivel. (2022) Structure-based design of small molecule and peptide inhibitors for selective targeting of ROCK1: an integrative computational approach. Journal of Biomolecular Structure and Dynamics 40:16, pages 7450-7468.
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Francesco Mincione, Alessio Nocentini & Claudiu T. Supuran. (2021) Advances in the discovery of novel agents for the treatment of glaucoma. Expert Opinion on Drug Discovery 16:10, pages 1209-1225.
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Lindsay Machen, Reza Razeghinejad & Jonathan S. Myers. (2020) Fixed-combination topical anti-hypertensive ophthalmic agents. Expert Opinion on Pharmacotherapy 21:10, pages 1269-1282.
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Zhuang Hou, Chuanchao Li, Yichuang Liu, Miao Zhang, Yitong Wang, Zhanfang Fan, Chun Guo, Bin Lin & Yang Liu. (2020) Design, synthesis and biological evaluation of carbohydrate-based sulphonamide derivatives as topical antiglaucoma agents through selective inhibition of carbonic anhydrase II. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 383-390.
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Claudiu T Supuran. (2019) The management of glaucoma and macular degeneration. Expert Opinion on Therapeutic Patents 29:10, pages 745-747.
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Articles from other publishers (21)

Yaodong You, Kun Zhu, Jie Wang, Qi Liang, Wen Li, Lin Wang, Baojun Guo, Jing Zhou, Xuanlin Feng & Jianyou Shi. (2023) ROCK inhibitor: Focus on recent updates. Chinese Chemical Letters 34:12, pages 108336.
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Gitika Kumari, T.S. Sampath Kumar, Mina Zare & Seeram Ramakrishna. (2023) Electrosprayed core-shell nanoparticles for sustained release fixed combination monotherapy in glaucoma treatment. Journal of Drug Delivery Science and Technology 88, pages 104923.
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Li Tang, Chao Tang, Ying Wang & Xiaolong Shi. 2023. Glaucoma - Recent Advances and New Perspectives. Glaucoma - Recent Advances and New Perspectives.
Ingeborg Stalmans, Kin Sheng Lim, Francesco Oddone, Marek Fichtl, Jose I. Belda, Anton Hommer, Guna Laganovska, Cédric Schweitzer, Bogomil Voykov, Tomasz Zarnowski & Gábor Holló. (2023) MERCURY-3: a randomized comparison of netarsudil/latanoprost and bimatoprost/timolol in open-angle glaucoma and ocular hypertension. Graefe's Archive for Clinical and Experimental Ophthalmology.
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Raul E. Ruiz-Lozano, Nadim S. Azar, Hazem M. Mousa, Manuel E. Quiroga-Garza, Seitaro Komai, Lorena Wheelock-Gutierrez, Cristian Cartes & Victor L. Perez. (2023) Ocular surface disease: a known yet overlooked side effect of topical glaucoma therapy. Frontiers in Toxicology 5.
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Elliot J. Glotfelty, Luis B. Tovar-y-Romo, Shih-Chang Hsueh, David Tweedie, Yazhou Li, Brandon K. Harvey, Barry J. Hoffer, Tobias E. Karlsson, Lars Olson & Nigel H. Greig. (2023) The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia. Cells 12:10, pages 1367.
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Claudiu T. Supuran. 2023. Nitric Oxide in Health and Disease. Nitric Oxide in Health and Disease 305 317 .
Kinga Czarnota-Łydka, Katarzyna Kucwaj-Brysz, Patryk Pyka, Wawrzyniec Haberek, Sabina Podlewska & Jadwiga Handzlik. (2022) Multitargeting the Action of 5-HT6 Serotonin Receptor Ligands by Additional Modulation of Kinases in the Search for a New Therapy for Alzheimer’s Disease: Can It Work from a Molecular Point of View?. International Journal of Molecular Sciences 23:15, pages 8768.
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Mario Cazzola, Paola Rogliani & Maria Gabriella Matera. (2022) The Future of Bronchodilators in COPD and Asthma. Archivos de Bronconeumología 58:2, pages 107-108.
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Tao Wang, Linlin Cao, Qikun Jiang & Tianhong Zhang. (2021) Topical Medication Therapy for Glaucoma and Ocular Hypertension. Frontiers in Pharmacology 12.
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Line Storgaard, Thuy Linh Tran, Josefine Clement Freiberg, Alexander S. Hauser & Miriam Kolko. (2021) Glaucoma Clinical Research: Trends in Treatment Strategies and Drug Development. Frontiers in Medicine 8.
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Carsten Schmelter, Kristian Nzogang Fomo, Natarajan Perumal, Norbert Pfeiffer & Franz H. Grus. (2021) Regulation of the HTRA2 Protease Activity by an Inhibitory Antibody-Derived Peptide Ligand and the Influence on HTRA2-Specific Protein Interaction Networks in Retinal Tissues. Biomedicines 9:8, pages 1013.
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Yumeng Sun, Yueshan Li, Zhuang Miao, Ruicheng Yang, Yun Zhang, Ming Wu, Guifeng Lin & Linli Li. (2021) Discovery of 3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one derivatives as a new class of ROCK inhibitors for the treatment of glaucoma. Bioorganic & Medicinal Chemistry Letters 45, pages 128138.
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Claudiu T. Supuran. (2021) Emerging role of carbonic anhydrase inhibitors. Clinical Science 135:10, pages 1233-1249.
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Junhui Shen, Yuanqi Wang & Ke Yao. (2021) Protection of retinal ganglion cells in glaucoma: Current status and future. Experimental Eye Research 205, pages 108506.
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Jasmin C. Lauer, Mischa Selig, Melanie L. Hart, Bodo Kurz & Bernd Rolauffs. (2021) Articular Chondrocyte Phenotype Regulation through the Cytoskeleton and the Signaling Processes That Originate from or Converge on the Cytoskeleton: Towards a Novel Understanding of the Intersection between Actin Dynamics and Chondrogenic Function. International Journal of Molecular Sciences 22:6, pages 3279.
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Wakako Kawarazaki & Toshiro Fujita. (2021) Role of Rho in Salt-Sensitive Hypertension. International Journal of Molecular Sciences 22:6, pages 2958.
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Ahmed A. Abdelghany, Francesco D'Oria & Jorge L. Alio. (2021) Surgery for glaucoma in modern corneal graft procedures. Survey of Ophthalmology 66:2, pages 276-289.
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Gloria Cimaglia, Marcela Votruba, James E. Morgan, Helder André & Pete A. Williams. (2020) Potential Therapeutic Benefit of NAD+ Supplementation for Glaucoma and Age-Related Macular Degeneration. Nutrients 12:9, pages 2871.
Crossref
Santoshi Naik, Abhijeet Pandey, Shaila A. Lewis, Bola Sadashiva Satish Rao & Srinivas Mutalik. (2020) Neuroprotection: A versatile approach to combat glaucoma. European Journal of Pharmacology 881, pages 173208.
Crossref
Rohit Narayan. (2020) We will ‘ROCK’ you? The role of Rho kinase inhibitors in eye care. Optician 2020:1, pages 8191-1.
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