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Research Paper

Benzo[g]quinazolin-based scaffold derivatives as dual EGFR/HER2 inhibitors

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Pages 67-73 | Received 13 Jul 2017, Accepted 29 Sep 2017, Published online: 03 Nov 2017

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Parth Bhatia, Vrinda Sharma, Ozair Alam, Ajay Manaithiya, Perwaiz Alam, Kahksha, Md Tauquir Alam & Mohd Imran. (2020) Novel quinazoline-based EGFR kinase inhibitors: A review focussing on SAR and molecular docking studies (2015-2019). European Journal of Medicinal Chemistry 204, pages 112640.
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Aiten M. Soliman, Mostafa M. Ghorab, Silvia Bua & Claudiu T. Supuran. (2020) Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity. European Journal of Medicinal Chemistry 200, pages 112449.
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Aiten M. Soliman & Mostafa M. Ghorab. (2019) Exploration of N-alkyl-2-[(4-oxo-3-(4-sulfamoylphenyl)-3,4-dihydroquinazolin-2-yl)thio]acetamide derivatives as anticancer and radiosensitizing agents. Bioorganic Chemistry 88, pages 102956.
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Mahmoud S. Abdelbaset, Mohamed Abdel-Aziz, Mohamed Ramadan, Mostafa H. Abdelrahman, Syed Nasir Abbas Bukhari, Taha F.S. Ali & Gamal El-Din A. Abuo-Rahma. (2019) Discovery of novel thienoquinoline-2-carboxamide chalcone derivatives as antiproliferative EGFR tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry 27:6, pages 1076-1086.
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Mostafa M. Ghorab, Mansour S. Alsaid & Aiten M. Soliman. (2018) Dual EGFR/HER2 inhibitors and apoptosis inducers: New benzo[g]quinazoline derivatives bearing benzenesulfonamide as anticancer and radiosensitizers. Bioorganic Chemistry 80, pages 611-620.
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