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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 35, 2020 - Issue 1
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Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors

Thomas S. Corrigana Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
,
Leilani M. Lotti Diaza Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
,
Sarah E. Bordera Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
,
Steven C. Ratiganb Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, USAView further author information
,
Kayla Q. Kaspera Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
,
Daniel Sojkac Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Ceske Budejovice, Czech RepublicView further author information
,
Pavla Fajtovad Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USAView further author information
,
Conor R. Caffreyd Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USAView further author information
,
Guy S. Salvesene Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USAView further author information
,
Craig A. McElroyb Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, USAView further author information
,
Christopher M. Hadada Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
&
Özlem Doğan Ekicia Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USA;f Department of Chemistry and Biochemistry, The Ohio State University at Newark, Newark, OH, USACorrespondence[email protected]
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Pages 1387-1402 | Received 13 Feb 2020, Accepted 08 May 2020, Published online: 07 Jul 2020

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Gopichand Gutti, Yiran He, William H. Coldren, Remy F. Lalisse, Sarah E. Border, Christopher M. Hadad, Craig A. McElroy & Özlem Doğan Ekici. (2023) In-silico guided design, screening, and molecular dynamic simulation studies for the identification of potential SARS-CoV-2 main protease inhibitors for the targeted treatment of COVID-19. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-18.
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Namrashee V. Mehta & Mariam S. Degani. (2023) The expanding repertoire of covalent warheads for drug discovery. Drug Discovery Today 28:12, pages 103799.
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Kai Fan Cheng, Sonya VanPatten, Mingzhu He & Yousef Al-Abed. (2022) Azapeptides -A History of Synthetic Milestones and Key Examples. Current Medicinal Chemistry 29:42, pages 6336-6358.
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Jinxing Hu, Shan Zhou & Weiying Guo. (2022) Construction of the coexpression network involved in the pathogenesis of thyroid eye disease via bioinformatics analysis. Human Genomics 16:1.
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Karima Tarchoun, Mo’ath Yousef & Zoltán Bánóczi. (2022) Azapeptides as an Efficient Tool to Improve the Activity of Biologically Effective Peptides. Future Pharmacology 2:3, pages 293-305.
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Maxwell Bowles & Caroline Proulx. 2021. Synthetic and Enzymatic Modifications of the Peptide Backbone. Synthetic and Enzymatic Modifications of the Peptide Backbone 169 190 .

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