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Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors
Thomas S. Corrigana Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
, Leilani M. Lotti Diaza Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
, Sarah E. Bordera Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
, Steven C. Ratiganb Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, USAView further author information
, Kayla Q. Kaspera Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
, Daniel Sojkac Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Ceske Budejovice, Czech RepublicView further author information
, Pavla Fajtovad Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USAView further author information
, Conor R. Caffreyd Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USAView further author information
, Guy S. Salvesene Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USAView further author information
, Craig A. McElroyb Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, USAView further author information
, Christopher M. Hadada Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USAView further author information
& Özlem Doğan Ekicia Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USA;f Department of Chemistry and Biochemistry, The Ohio State University at Newark, Newark, OH, USACorrespondence[email protected]
View further author information
show allView further author information
Pages 1387-1402
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Received 13 Feb 2020, Accepted 08 May 2020, Published online: 07 Jul 2020
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