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Review

Recent advances in nontoxic Escherichia coli heat-labile toxin and its derivative adjuvants

Pages 1361-1371 | Received 24 Dec 2015, Accepted 22 Apr 2016, Published online: 12 May 2016

Keep up to date with the latest research on this topic with citation updates for this article.

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Fei Su, Yige Wu, Junxing Li, Yee Huang, Bin Yu, Lihua Xu, Yin Xue, Chenwen Xiao & Xiufang Yuan. (2021) Escherichia coli Heat-Labile Enterotoxin B Subunit Combined with Ginsenoside Rg1 as an Intranasal Adjuvant Triggers Type I Interferon Signaling Pathway and Enhances Adaptive Immune Responses to an Inactivated PRRSV Vaccine in ICR Mice. Vaccines 9:3, pages 266.
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Xiaoyan Peng, Rongguang Zhang, Chen Wang, Feiyan Yu, Mingyang Yu, Shuaiyin Chen, Qingtang Fan, Yuanlin Xi & Guangcai Duan. (2019) E. coli Enterotoxin LtB Enhances Vaccine-Induced Anti-H. pylori Protection by Promoting Leukocyte Migration into Gastric Mucus via Inflammatory Lesions. Cells 8:9, pages 982.
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Qiangde Duan, Pengpeng Xia, Rahul Nandre, Weiping Zhang & Guoqiang Zhu. (2019) Review of Newly Identified Functions Associated With the Heat-Labile Toxin of Enterotoxigenic Escherichia coli. Frontiers in Cellular and Infection Microbiology 9.
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Raj Kumar, Thomas M. Feltrup, Roshan V. Kukreja, Kruti B. Patel, Shuowei Cai & Bal Ram Singh. (2019) Evolutionary Features in the Structure and Function of Bacterial Toxins. Toxins 11:1, pages 15.
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Fei SU, Lihua XU, Yin XUE, Junxing LI, Yuan FU, Bin YU, Sai WANG & Xiufang YUAN. (2019) Th1-biased immunoadjuvant effect of the recombinant B subunit of an <i>Escherichia coli</i> heat-labile enterotoxin on an inactivated porcine reproductive and respiratory syndrome virus antigen via intranasal immunization in mice. Journal of Veterinary Medical Science 81:10, pages 1475-1484.
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Verónica Araceli Márquez-Escobar, Bernardo Bañuelos-Hernández & Sergio Rosales-Mendoza. (2018) Expression of a Zika virus antigen in microalgae: Towards mucosal vaccine development. Journal of Biotechnology 282, pages 86-91.
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Jinzhu Ma, Liquan Yu, Baifen Song, Yongzhong Yu, Shaoduo Zhang, Yuhua Wei, Zhijun Wu, Di Yao, Wei Yu, Zhanbo Zhu & Yudong Cui. (2018) The double adjuvants LTB and CpG significantly enhanced the immuno-protective effects of recombinant GIT derived from Staphylococcus aureus and Streptococcus in mice. Journal of Medical Microbiology 67:3, pages 432-440.
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Cameron H. Flayer, Sarah S. Killingbeck, Erik Larson, Zoulfia Allakhverdi & Angela Haczku. 2018. Immunopharmacology and Inflammation. Immunopharmacology and Inflammation 57 84 .
Narges Zeinalzadeh, Ali Hatef Salmanian, Goli Goujani, Jafar Amani, Ghasem Ahangari, Asal Akhavian & Mahyat Jafari. (2017) A Chimeric protein of CFA/I, CS6 subunits and LTB/STa toxoid protects immunized mice against enterotoxigenic Escherichia coli . Microbiology and Immunology 61:7, pages 272-279.
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S. S. Killingbeck, M. Q. Ge & A. Haczku. (2017) Patching it together: epicutaneous vaccination with heat-labile Escherichia coli toxin against birch pollen allergy . Allergy 72:1, pages 5-8.
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Lin Liu, Yongping Ma, Huicong Zhou & Mingjun Wu. (2016) Quantitative Proteomic Analysis of Escherichia coli Heat-Labile Toxin B Subunit (LTB) with Enterovirus 71 (EV71) Subunit VP1. International Journal of Molecular Sciences 17:9, pages 1419.
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