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Review

Do varicella vaccination programs change the epidemiology of herpes zoster? A comprehensive review, with focus on the United States

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Pages 793-811 | Received 15 Mar 2019, Accepted 17 Jul 2019, Published online: 12 Aug 2019

Keep up to date with the latest research on this topic with citation updates for this article.

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Ru Han, Jorge A. Gomez, Bruna de Veras, Thatiana Pinto, Adriana Guzman-Holst, Javier Nieto & Désirée A. M. van Oorschot. (2023) How large could the public health impact of introducing recombinant zoster vaccination for people aged ≥50 years in five Latin American countries be?. Human Vaccines & Immunotherapeutics 19:1.
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Margaret K. Doll & Barry DeCoster. (2020) Vaccine-Associated Shingles: What Do We Owe Varicella Vaccine Recipients in Adulthood?. The American Journal of Bioethics 20:9, pages 78-80.
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Florence Kauffmann, Angela Bechini, Paolo Bonanni, Giacomo Casabona & Peter Wutzler. (2020) Varicella vaccination in Italy and Germany – different routes to success: a systematic review. Expert Review of Vaccines 19:9, pages 843-869.
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Articles from other publishers (37)

Kazuhiro Uda, Yusuke Okubo, Mitsuru Tsuge, Hirokazu Tsukahara & Isao Miyairi. (2023) Impacts of routine varicella vaccination program and COVID-19 pandemic on varicella and herpes zoster incidence and health resource use among children in Japan. Vaccine 41:34, pages 4958-4966.
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Colleen Burgess, Salome Samant, Thomas leFevre, Carsten Schade Larsen & Manjiri Pawaskar. (2023) Universal varicella vaccination in Denmark: Modeling public health impact, age-shift, and cost-effectiveness. PLOS Global Public Health 3:4, pages e0001743.
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Fernanda Rodrigues, Robin Marlow, Catarina Gouveia, Paula Correia, Ana Brett, Catarina Silva, Inês Gameiro, Inês Rua, João Dias, Marta Martins, Rui Diogo, Teresa Lopes, Elsa Hipólito, Diana Moreira, Manuela Costa Alves, Filipa Prata, Miguel Labrusco, Susana Gomes, Alexandre Fernandes, Alexandra Andrade, Catarina Granjo Morais, Maria João Virtuoso, Maria Manuel Zarcos, Ana Teresa Raposo, Adam Boon & Adam Finn. (2023) Prospective study of loss of health-related quality adjusted life years in children and their families due to uncomplicated and hospitalised varicella. Vaccine 41:6, pages 1182-1189.
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Ann M. Arvin. 2023. Principles and Practice of Pediatric Infectious Diseases. Principles and Practice of Pediatric Infectious Diseases 1084 1092.e2 .
Yang Sun, Lingling Huang, Jianqi Nie, Kai Feng, Yupeng Liu & Zhonghu Bai. (2022) Development of a perfusion process for serum-free adenovirus vector herpes zoster vaccine production. AMB Express 12:1.
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Fangjun Zhou, Jessica Leung, Mona Marin, Kathleen L Dooling, Tara C Anderson & Ismael R Ortega-Sanchez. (2022) Health and Economic Impact of the United States Varicella Vaccination Program, 1996–2020. The Journal of Infectious Diseases 226:Supplement_4, pages S463-S469.
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Jessica Leung, Kathleen Dooling, Mona Marin, Tara C Anderson & Rafael Harpaz. (2022) The Impact of Universal Varicella Vaccination on Herpes Zoster Incidence in the United States: Comparison of Birth Cohorts Preceding and Following Varicella Vaccination Program Launch. The Journal of Infectious Diseases 226:Supplement_4, pages S470-S477.
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Marci Drees & David J Weber. (2022) Prevention and Control of Nosocomial Varicella During the United States Varicella Vaccination Program Era. The Journal of Infectious Diseases 226:Supplement_4, pages S456-S462.
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Mirella Mourad, Michael Gershon, Satish K. Mehta, Brian E. Crucian, Nicole Hubbard, Jing Zhang & Anne Gershon. (2022) Silent Reactivation of Varicella Zoster Virus in Pregnancy: Implications for Maintenance of Immunity to Varicella. Viruses 14:7, pages 1438.
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Wei Wang, Dequan Pan, Tong Cheng & Hua Zhu. (2022) Rational Design of a Skin- and Neuro-Attenuated Live Varicella Vaccine: A Review and Future Perspectives. Viruses 14:5, pages 848.
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Dong-Kyu Lim & Chang-Eun Park. (2022) Relationship between the Thyroid Hormone and Viral Infections in Pregnancy. Korean Journal of Clinical Laboratory Science 54:1, pages 28-37.
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Anne A Gershon & Michael D Gershon. (2022) Widespread Use of Varicella Vaccine Does Not Reduce Immunity to Zoster of Others. The Journal of Infectious Diseases 225:3, pages 361-363.
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Stephane Carryn, Brigitte Cheuvart, Michael Povey, Alemnew F Dagnew, Rafael Harpaz, Robbert van der Most & Giacomo Casabona. (2022) No Consistent Evidence of Decreased Exposure to Varicella-Zoster Virus Among Older Adults in Countries with Universal Varicella Vaccination. The Journal of Infectious Diseases 225:3, pages 413-421.
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Katarina Widgren, GianPaolo Scalia Tomba, Ka Yin Leung & Johan Giesecke. (2022) Modelling varicella vaccination – What does a lack of surge in herpes zoster incidence tell us about exogenous boosting?. Vaccine 40:4, pages 673-681.
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Nidhi Shah & A. Yasmine Kirkorian. 2022. Pediatric Dermatology. Pediatric Dermatology 108 132 .
Manjiri Pawaskar, Estelle Méroc, Salome Samant, Elmira Flem, Goran Bencina, Margarita Riera-Montes & Ulrich Heininger. (2021) Economic burden of varicella in Europe in the absence of universal varicella vaccination. BMC Public Health 21:1.
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Esse Ifebi Herve Akpo, Olivier Cristeau, Manjit Hunjan & Giacomo Casabona. (2021) Epidemiological Impact and Cost-Effectiveness of Varicella Vaccination Strategies in the United Kingdom. Clinical Infectious Diseases 73:11, pages e3617-e3626.
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Carlo Di Pietrantonj, Alessandro Rivetti, Pasquale Marchione, Maria Grazia Debalini & Vittorio Demicheli. (2021) Vaccines for measles, mumps, rubella, and varicella in children. Cochrane Database of Systematic Reviews 2021:11.
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Ellen Rafferty, Laura Reifferscheid, Margaret L. Russell, Stephanie Booth, Lawrence W. Svenson & Shannon E. MacDonald. (2021) The impact of varicella vaccination on paediatric herpes zoster epidemiology: a Canadian population-based retrospective cohort study. European Journal of Clinical Microbiology & Infectious Diseases 40:11, pages 2363-2370.
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Anne A Gershon, Michael D Gershon & Eugene D Shapiro. (2021) Live Attenuated Varicella Vaccine: Prevention of Varicella and of Zoster. The Journal of Infectious Diseases 224:Supplement_4, pages S387-S397.
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Rafael Harpaz. (2021) The Effectiveness of Recombinant Zoster Vaccine: Observations in the Wild. Clinical Infectious Diseases 73:6, pages 957-960.
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Beth H. Rutstein, Sabrina Gmuca, Jeffrey S. Gerber, Tristan Lim, Melissa Argraves & Alexis Ogdie. (2021) Validation of coding algorithms for the identification of herpes zoster among children. Pharmacoepidemiology and Drug Safety 30:9, pages 1162-1167.
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Gary S Goldman. (2021) Insights on the Impact of External and Internal Boosting on Varicella-Zoster Virus Reactivation Based on Evidence From the First Decade of the United States Universal Varicella Vaccination Program. Cureus.
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Ellen Wolff, Katarina Widgren, Gianpaolo Scalia Tomba, Adam Roth, Tiia Lep & Sören Andersson. (2021) Cost-effectiveness of varicella and herpes zoster vaccination in Sweden: An economic evaluation using a dynamic transmission model. PLOS ONE 16:5, pages e0251644.
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Jiyeon Suh, Taeyong Lee, Jae-Ki Choi, Jeehyun Lee & Sun Hee Park. (2021) The impact of two-dose varicella vaccination on varicella and herpes zoster incidence in South Korea using a mathematical model with changing population demographics. Vaccine 39:18, pages 2575-2583.
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Brent Hodgkinson, Tianjiao Wang, Joshua Byrnes & Paul Scuffham. (2021) Modelling a cost-effective vaccination strategy for the prevention of varicella and herpes zoster infection: A systematic review. Vaccine 39:9, pages 1370-1382.
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Francisco José Álvarez García, María José Cilleruelo Ortega, Javier Álvarez Aldeán, María Garcés-Sánchez, Nuria García Sánchez, Elisa Garrote Llanos, Ángel Hernández Merino, Antonio Iofrío de Arce, Abián Montesdeoca Melián, María Luisa Navarro Gómez & Jesús Ruiz-Contreras. (2021) Calendario de vacunaciones de la Asociación Española de Pediatría: recomendaciones 2021. Anales de Pediatría 94:1, pages 53.e1-53.e10.
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Francisco José Álvarez García, María José Cilleruelo Ortega, Javier Álvarez Aldeán, María Garcés-Sánchez, Nuria García Sánchez, Elisa Garrote Llanos, Ángel Hernández Merino, Antonio Iofrío de Arce, Abián Montesdeoca Melián, María Luisa Navarro Gómez & Jesús Ruiz-Contreras. (2021) Immunisation schedule of the Pediatric Spanish Association: 2021 recommendations. Anales de Pediatría (English Edition) 94:1, pages 53.e1-53.e10.
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Ritu Swali, Claire Wiggins, Sahira Farooq, Radhika A. Shah & Emily Limmer. 2021. Overcoming Antimicrobial Resistance of the Skin. Overcoming Antimicrobial Resistance of the Skin 111 129 .
Rafael Harpaz. (2020) How Little We Know Herpes Zoster. The Journal of Infectious Diseases 222:5, pages 708-711.
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Rafael Harpaz. (2020) Teach your parents well: Pediatric recipients of varicella vaccines yield insights for adults regarding herpes zoster. Vaccine 38:37, pages 5877-5879.
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Regnerus A. Vos, Liesbeth Mollema, Michiel van Boven, Alies van Lier, Gaby Smits, Alcira V.A. Janga-Jansen, Sharda Baboe-Kalpoe, Koen Hulshof, Ymkje Stienstra, Fiona R.M. van der Klis & Hester E. de Melker. (2020) High varicella zoster virus susceptibility in Caribbean island populations: Implications for vaccination. International Journal of Infectious Diseases 94, pages 16-24.
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Carlo Di Pietrantonj, Alessandro Rivetti, Pasquale Marchione, Maria Grazia Debalini & Vittorio Demicheli. (2020) Vaccines for measles, mumps, rubella, and varicella in children. Cochrane Database of Systematic Reviews.
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R. Cohen, D. Pinquier & H. Haas. (2020) Les vaccins contre la varicelle. Journal de Pédiatrie et de Puériculture 33:1, pages 26-30.
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Lorraine Larsen Rosamilia. (2019) Herpes Zoster Presentation, Management, and Prevention: A Modern Case-Based Review. American Journal of Clinical Dermatology 21:1, pages 97-107.
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Francisco José Álvarez García, María José Cilleruelo Ortega, Javier Álvarez Aldeán, María Garcés-Sánchez, Nuria García Sánchez, Elisa Garrote Llanos, Ángel Hernández Merino, Antonio Iofrío de Arce, Manuel Merino Moína, Abián Montesdeoca Melián, María Luisa Navarro Gómez, Jesús Ruiz-Contreras, Francisco José Álvarez García, María José Cilleruelo Ortega, Javier Álvarez Aldeán, María Garcés-Sánchez, Nuria García Sánchez, Elisa Garrote Llanos, Ángel Hernández Merino, Antonio Iofrío de Arce, Manuel Merino Moína, Abián Montesdeoca Melián, María Luisa Navarro Gómez & Jesús Ruiz-Contreras. (2020) Calendario de vacunaciones de la Asociación Española de Pediatría: recomendaciones 2020. Anales de Pediatría 92:1, pages 52.e1-52.e10.
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Francisco José Álvarez García, María José Cilleruelo Ortega, Javier Álvarez Aldeán, María Garcés-Sánchez, Nuria García Sánchez, Elisa Garrote Llanos, Ángel Hernández Merino, Antonio Iofrío de Arce, Manuel Merino Moína, Abián Montesdeoca Melián, María Luisa Navarro Gómez, Jesús Ruiz-Contreras, Francisco José Álvarez García, María José Cilleruelo Ortega, Javier Álvarez Aldeán, María Garcés-Sánchez, Nuria García Sánchez, Elisa Garrote Llanos, Ángel Hernández Merino, Antonio Iofrío de Arce, Manuel Merino Moína, Abián Montesdeoca Melián, María Luisa Navarro Gómez & Jesús Ruiz-Contreras. (2020) IMMUNISATION SCHEDULE OF THE SPANISH ASSOCIATION OF PAEDIATRICS: 2020 RECOMMENDATIONS. Anales de Pediatría (English Edition) 92:1, pages 52.e1-52.e10.
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