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Original Articles

Concept of Assessing Nanoparticle Hazards Considering Nanoparticle Dosemetric and Chemical/Biological Response Metrics

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Pages 445-461 | Published online: 12 Feb 2010

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Theresa E. Boots, Alyssa M. Kogel, Nathan M. Drew & Eileen D. Kuempel. (2021) Utilizing literature-based rodent toxicology data to derive potency estimates for quantitative risk assessment. Nanotoxicology 15:6, pages 740-760.
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Gemma Janer, Robert Landsiedel & Wendel Wohlleben. (2021) Rationale and decision rules behind the ECETOC NanoApp to support registration of sets of similar nanoforms within REACH. Nanotoxicology 15:2, pages 145-166.
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Arek M Engstrom, Ryan A Faase, Grant W Marquart, Joe E Baio, Marilyn R Mackiewicz & Stacey L Harper. (2020) Size-Dependent Interactions of Lipid-Coated Gold Nanoparticles: Developing a Better Mechanistic Understanding Through Model Cell Membranes and in vivo Toxicity. International Journal of Nanomedicine 15, pages 4091-4104.
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Dong-Keun Lee, Sangwook Ha, Soyeon Jeon, Jiyoung Jeong, Dong-Jae Kim, Seung Whan Lee & Wan-Seob Cho. (2020) The sp/sp carbon ratio as a modulator of in vivo and in vitro toxicity of the chemically purified detonation-synthesized nanodiamond via the reactive oxygen species generation. Nanotoxicology 14:9, pages 1213-1226.
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Yang Liu, Jun Ji, Le Ji, Yuanyuan Li, Bowen Zhang, Tongwang Yang, Jing Yang, Liping Lv & Gang Wu. (2019) Translocation of intranasal (i.n.) instillation of different-sized cerium dioxide (CeO2) particles: potential adverse effects in mice. Journal of Toxicology and Environmental Health, Part A 82:20, pages 1069-1075.
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Youngju Han, Dong-Keon Lee, Sung-Hyun Kim, Seonghan Lee, Soyeon Jeon & Wan-Seob Cho. (2018) High inflammogenic potential of rare earth oxide nanoparticles: the New Hazardous Entity. Nanotoxicology 12:7, pages 712-728.
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Helinor J. Johnston, Rachel Verdon, Suzanne Gillies, David M. Brown, Teresa F. Fernandes, Theodore B. Henry, Adriano G. Rossi, Lang Tran, Carl Tucker, Charles R. Tyler & Vicki Stone. (2018) Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials. Critical Reviews in Toxicology 48:3, pages 252-271.
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Jiyoung Jeong, Seonghan Lee, Sung-Hyun Kim, Youngju Han, Dong-Keon Lee, Jun-Young Yang, Jayoung Jeong, Changhyun Roh, Yun Suk Huh & Wan-Seob Cho. (2016) Evaluation of the dose metric for acute lung inflammogenicity of fast-dissolving metal oxide nanoparticles. Nanotoxicology 10:10, pages 1448-1457.
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Sung-Hyun Hwang, Frank Thielbeer, Jiyoung Jeong, Youngju Han, Sunay V. Chankeshwara, Mark Bradley & Wan-Seob Cho. (2016) Dual contribution of surface charge and protein-binding affinity to the cytotoxicity of polystyrene nanoparticles in nonphagocytic A549 cells and phagocytic THP-1 cells. Journal of Toxicology and Environmental Health, Part A 79:20, pages 925-937.
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Jeongeun Kim, Sunay V. Chankeshwara, Frank Thielbeer, Jiyoung Jeong, Ken Donaldson, Mark Bradley & Wan-Seob Cho. (2016) Surface charge determines the lung inflammogenicity: A study with polystyrene nanoparticles. Nanotoxicology 10:1, pages 94-101.
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Ali Kermanizadeh, Ilse Gosens, Laura MacCalman, Helinor Johnston, Pernille H. Danielsen, Nicklas R. Jacobsen, Anke-Gabriele Lenz, Teresa Fernandes, Roel P. F. Schins, Flemming R. Cassee, Håkan Wallin, Wolfgang Kreyling, Tobias Stoeger, Steffen Loft, Peter Møller, Lang Tran & Vicki Stone. (2016) A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health—ENPRA Project—The Highlights, Limitations, and Current and Future Challenges. Journal of Toxicology and Environmental Health, Part B 19:1, pages 1-28.
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Eileen D. Kuempel, Lisa M. Sweeney, John B. Morris & Annie M. Jarabek. (2015) Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation. Journal of Occupational and Environmental Hygiene 12:sup1, pages S18-S40.
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D. Gayle DeBord, Lyle Burgoon, Stephen W. Edwards, Lynne T. Haber, M. Helen Kanitz, Eileen Kuempel, Russell S. Thomas & Berran Yucesoy. (2015) Systems Biology and Biomarkers of Early Effects for Occupational Exposure Limit Setting. Journal of Occupational and Environmental Hygiene 12:sup1, pages S41-S54.
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Anoop K. Pal, Dhimiter Bello, Joel Cohen & Philip Demokritou. (2015) Implications of in vitro dosimetry on toxicological ranking of low aspect ratio engineered nanomaterials. Nanotoxicology 9:7, pages 871-885.
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Amanda Juric, Richard Meldrum & Eric N. Liberda. (2015) Achieving Control of Occupational Exposures to Engineered Nanomaterials. Journal of Occupational and Environmental Hygiene 12:8, pages 501-508.
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Abdullah A Alkahtane. (2015) Nanosilica exerts cytotoxicity and apoptotic response via oxidative stress in mouse embryonic fibroblasts. Toxicological & Environmental Chemistry 97:5, pages 651-662.
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Daoud Ali & Huma Ali. (2015) Susceptibility of the freshwater pulmonate snail Lymnea luteola L. to copper oxide nanoparticle. Toxicological & Environmental Chemistry 97:5, pages 576-587.
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Günter Oberdörster, Vincent Castranova, Bahman Asgharian & Phil Sayre. (2015) Inhalation Exposure to Carbon Nanotubes (CNT) and Carbon Nanofibers (CNF): Methodology and Dosimetry. Journal of Toxicology and Environmental Health, Part B 18:3-4, pages 121-212.
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Katherine M. Dunnick, Melissa A. Badding, Diane Schwegler-Berry, Jonathan M. Patete, Christopher Koenigsmann, Stanislaus S. Wong & Stephen S. Leonard. (2014) The Effect of Tungstate Nanoparticles on Reactive Oxygen Species and Cytotoxicity in Raw 264.7 Mouse Monocyte Macrophage Cells. Journal of Toxicology and Environmental Health, Part A 77:20, pages 1251-1268.
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Xue Z. Wang, Yang Yang, Ruifa Li, Catherine Mcguinnes, Janet Adamson, Ian L. Megson & Kenneth Donaldson. (2014) Principal component and causal analysis of structural and acute in vitro toxicity data for nanoparticles. Nanotoxicology 8:5, pages 465-476.
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Sujatha Purushothaman, Azhwar Raghunath, Vasanth Dhakshinamoorthy, Lakshmikanthan Panneerselvam & Ekambaram Perumal. (2014) Acute exposure to titanium dioxide (TiO2) induces oxidative stress in zebrafish gill tissues. Toxicological & Environmental Chemistry 96:6, pages 890-905.
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Madhu Khatri, Dhimiter Bello, Peter Gaines, John Martin, Anoop K Pal, Rebecca Gore & Susan Woskie. (2013) Nanoparticles from photocopiers induce oxidative stress and upper respiratory tract inflammation in healthy volunteers. Nanotoxicology 7:5, pages 1014-1027.
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Joel Cohen, Glen DeLoid, Georgios Pyrgiotakis & Philip Demokritou. (2013) Interactions of engineered nanomaterials in physiological media and implications for in vitro dosimetry. Nanotoxicology 7:4, pages 417-431.
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Jenny R. Roberts, Walter McKinney, Hong Kan, Kristine Krajnak, David G. Frazer, Treye A. Thomas, Stacey Waugh, Allison Kenyon, Robert I. MacCuspie, Vincent A. Hackley & Vincent Castranova. (2013) Pulmonary and Cardiovascular Responses of Rats to Inhalation of Silver Nanoparticles. Journal of Toxicology and Environmental Health, Part A 76:11, pages 651-668.
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Helinor Johnston, Giulio Pojana, Stefano Zuin, Nicklas Raun Jacobsen, Peter Møller, Steffen Loft, Manuela Semmler-Behnke, Catherine McGuiness, Dominique Balharry, Antonio Marcomini, Håkan Wallin, Wolfgang Kreyling, Ken Donaldson, Lang Tran & Vicki Stone. (2013) Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges. Critical Reviews in Toxicology 43:1, pages 1-20.
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Brandi N. Snyder-Talkington, Yong Qian, Vincent Castranova & Nancy L. Guo. (2012) New Perspectives for in Vitro Risk Assessment of Multiwalled Carbon Nanotubes: Application of Coculture and Bioinformatics. Journal of Toxicology and Environmental Health, Part B 15:7, pages 468-492.
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Shu-Feng Hsieh, Dhimiter Bello, Daniel F. Schmidt, Anoop K. Pal & Eugene J. Rogers. (2012) Biological oxidative damage by carbon nanotubes: Fingerprint or footprint?. Nanotoxicology 6:1, pages 61-76.
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Jenny R. Roberts, Rebecca S. Chapman, Vijay R. Tirumala, Alamgir Karim, Bean T. Chen, Diane Schwegler-Berry, Aleksandr B. Stefaniak, Stephen S. Leonard & James M. Antonini. (2011) Toxicological Evaluation of Lung Responses After Intratracheal Exposure to Non-Dispersed Titanium Dioxide Nanorods. Journal of Toxicology and Environmental Health, Part A 74:12, pages 790-810.
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Karin Aschberger, Helinor J. Johnston, Vicki Stone, Robert J. Aitken, Steven M. Hankin, Sheona A. K. Peters, C. Lang Tran & Frans M. Christensen. (2010) Review of carbon nanotubes toxicity and exposure—Appraisal of human health risk assessment based on open literature. Critical Reviews in Toxicology 40:9, pages 759-790.
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