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Journal of Toxicology and Environmental Health, Part A
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Volume 76, 2013 - Issue 11
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Original Articles

Popcorn Flavoring Effects on Reactivity of Rat Airways in Vivo and in Vitro

Eric J. Zaccone Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia, USA
,
Janet A. Thompson Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Dovenia S. Ponnoth Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Amy M. Cumpston Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
W. Travis Goldsmith Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Mark C. Jackson Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Michael L. Kashon Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
David G. Frazer Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Ann F. Hubbs Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Michael J. Shimko Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia, USA
&
Jeffrey S. Fedan Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USACorrespondence[email protected]
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Pages 669-689 | Received 03 Jan 2013, Accepted 12 Apr 2013, Published online: 13 Aug 2013

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Nárcia Mariana Fonseca NUNES, Jurandy do Nascimento SILVA, Micaely Lorrana Pereira CONCEIÇÃO, Joaquim Soares da COSTA JÚNIOR, Edymilais da Silva SOUSA, Maria das Dores Alves de OLIVEIRA, Antonia Maria das Graças Lopes CITÓ, Dalton DITTZ, Ana Paula PERON & Paulo Michel Pinheiro FERREIRA. (2023) In vitro and in vivo acute toxicity of an artificial butter flavoring. Journal of Toxicology and Environmental Health, Part A 86:6, pages 181-197.
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Jeffrey W. Card, Kevin M. Scaife & Lois A. Haighton. (2022) Review of evidence relating to occupational exposure limits for alpha-diketones and acetoin, and considerations for deriving an occupational exposure limit for 2,3-pentanedione. Critical Reviews in Toxicology 52:9, pages 715-730.
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Articles from other publishers (21)

Annette R. Iannucci & Janet M. Carter. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 243 256 .
Christina Drake, Matthias M. Wehr, Walter Zobl, Jeannette Koschmann, David De Lucca, Britta A. Kühne, Tanja Hansen, Jan Knebel, Detlef Ritter, Jan Boei, Harry Vrieling, Annette Bitsch & Sylvia E. Escher. (2023) Substantiate a read-across hypothesis by using transcriptome data—A case study on volatile diketones. Frontiers in Toxicology 5.
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Vito Anggarino Damay, Setiawan, Ronny Lesmana, M. Rizki Akbar, Antonia Anna Lukito, Vita M. Tarawan, Januar W. Martha & J. Nugroho. (2022) Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences. International Journal of Vascular Medicine 2022, pages 1-11.
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Bénédicte Cesselin, Céline Henry, Alexandra Gruss, Karine Gloux & Philippe Gaudu. (2021) Mechanisms of Acetoin Toxicity and Adaptive Responses in an Acetoin-Producing Species, Lactococcus lactis. Applied and Environmental Microbiology 87:24.
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Wei Xie, Kwan Hyun Kim, Robert Vince & Swati S. More. (2021) The Amyloid Aggregation Accelerator Diacetyl Prevents Cognitive Decline in Alzheimer’s Mouse Models. Chemical Research in Toxicology 34:5, pages 1355-1366.
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Konstantinos Farsalinos. 2021. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure 617 643 .
Anna Merecz-Sadowska, Przemyslaw Sitarek, Hanna Zielinska-Blizniewska, Katarzyna Malinowska, Karolina Zajdel, Lukasz Zakonnik & Radoslaw Zajdel. (2020) A Summary of In Vitro and In Vivo Studies Evaluating the Impact of E-Cigarette Exposure on Living Organisms and the Environment. International Journal of Molecular Sciences 21:2, pages 652.
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Ann F. Hubbs, Kathleen Kreiss, Kristin J. Cummings, Kara L. Fluharty, Ryan O’ConnellAllison Cole, Tiana M. Dodd, Sidney M. ClingermanJordan R. FlesherRebecca LeeSamantha PagelLori A. Battelli, Amy Cumpston, Mark Jackson, Michael Kashon, Marlene S. Orandle, Jeffrey S. Fedan & Krishnan Sriram. (2019) Flavorings-Related Lung Disease: A Brief Review and New Mechanistic Data. Toxicologic Pathology 47:8, pages 1012-1026.
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Carl A. Vas, Andrew Porter & Kevin McAdam. (2019) Acetoin is a precursor to diacetyl in e-cigarette liquids. Food and Chemical Toxicology 133, pages 110727.
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Hae-Ryung Park, Michael O’Sullivan, Jose Vallarino, Maya Shumyatcher, Blanca E. Himes, Jin-Ah Park, David C. Christiani, Joseph Allen & Quan Lu. (2019) Transcriptomic response of primary human airway epithelial cells to flavoring chemicals in electronic cigarettes. Scientific Reports 9:1.
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Kristen A. Russ, Janet A. Thompson, Michael Kashon, Dale W. Porter, Sherri A. Friend, Walter McKinney & Jeffrey S. Fedan. (2019) Comparison of multi-wall carbon nanotube and nitrogen-doped multi-wall carbon nanotube effects on lung function and airway reactivity in rats. Toxicology and Applied Pharmacology 364, pages 153-163.
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Robert M. Park & Stephen J. Gilbert. (2018) Pulmonary Impairment and Risk Assessment in a Diacetyl-Exposed Population. Journal of Occupational & Environmental Medicine 60:6, pages 496-506.
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Andrea Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 135 160 .
K.E. Farsalinos. 2017. Analytical Assessment of E-Cigarettes. Analytical Assessment of E-Cigarettes 75 122 .
Ann F. Hubbs, Kara L. Fluharty, Rebekah J. Edwards, Jamie L. Barnabei, John T. Grantham, Scott M. Palmer, Francine Kelly, Linda M. Sargent, Steven H. Reynolds, Robert R. Mercer, Madhusudan P. Goravanahally, Michael L. Kashon, John C. Honaker, Mark C. Jackson, Amy M. Cumpston, William T. Goldsmith, Walter McKinney, Jeffrey S. Fedan, Lori A. Battelli, Tiffany Munro, Winnie Bucklew-Moyers, Kimberly McKinstry, Diane Schwegler-Berry, Sherri Friend, Alycia K. Knepp, Samantha L. Smith & Krishnan Sriram. (2016) Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity. The American Journal of Pathology 186:11, pages 2887-2908.
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A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 2525 2570 .
Van K. Holden & Stella E. Hines. (2016) Update on flavoring-induced lung disease. Current Opinion in Pulmonary Medicine 22:2, pages 158-164.
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Eric J. Zaccone, W. Travis Goldsmith, Michael J. Shimko, J.R. Wells, Diane Schwegler-Berry, Patsy A. Willard, Shannon L. Case, Janet A. Thompson & Jeffrey S. Fedan. (2015) Diacetyl and 2,3-pentanedione exposure of human cultured airway epithelial cells: Ion transport effects and metabolism of butter flavoring agents. Toxicology and Applied Pharmacology 289:3, pages 542-549.
Crossref
. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 58 .
Stephanie ClarkCarl K. Winter. (2015) Diacetyl in Foods: A Review of Safety and Sensory Characteristics. Comprehensive Reviews in Food Science and Food Safety 14:5, pages 634-643.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 42 .

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