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Original Articles

The Flow-Past Chamber: An Improved Nose-Only Exposure System for Rodents

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Pages 923-928 | Published online: 04 Jun 2010

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Read on this site (38)

Anbo Wang, Amit Gupta, Michael D. Grimm, David T. Pressburger, Barney R. Sparrow, Jamie S. Richey, John R. Shaw, Karen E. Elsass, Georgia K. Roberts, Pei-Li Yao, Matthew D. Stout, Benjamin J. Ellis & Robyn L. Ray. (2023) Natural mineral fibers: conducting inhalation toxicology studies – part A: Libby Amphibole aerosol generation and characterization method development. Inhalation Toxicology 35:7-8, pages 201-213.
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Anbo Wang, Amit Gupta, Michael D. Grimm, David T. Pressburger, Barney R. Sparrow, Jamie S. Richey, John R. Shaw, Karen E. Elsass, Georgia K. Roberts, Pei-Li Yao, Matthew D. Stout, Benjamin J. Ellis & Robyn L. Ray. (2023) Natural mineral fibers: conducting inhalation toxicology studies—part B: development of a nose-only exposure system for repeat-exposure in vivo study of Libby amphibole aerosol. Inhalation Toxicology 35:7-8, pages 214-229.
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Francesco Lucci, Wei Teck Tan, Subash Krishnan, Julia Hoeng, Patrick Vanscheeuwijck, Rudolph Jaeger & Arkadiusz Kuczaj. (2020) Experimental and computational investigation of a nose-only exposure chamber. Aerosol Science and Technology 54:3, pages 277-290.
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Jennifer L. Plahovinsak, Mark R. Perry, Katherine A. Knostman, Robert Segal & Michael C. Babin. (2015) Characterization of a nose-only inhaled phosgene acute lung injury mouse model . Inhalation Toxicology 27:14, pages 832-840.
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Günter Oberdörster, Vincent Castranova, Bahman Asgharian & Phil Sayre. (2015) Inhalation Exposure to Carbon Nanotubes (CNT) and Carbon Nanofibers (CNF): Methodology and Dosimetry. Journal of Toxicology and Environmental Health, Part B 18:3-4, pages 121-212.
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Heather Conway, Kelly J. Dix, Jacob D. McDonald, Rodney A. Miller, Henry G. Wall, Ronald K. Wolff & Matthew D. Reed. (2013) Comparison of inhalation toxicity studies of gentamicin in rats and dogs. Inhalation Toxicology 25:13, pages 714-724.
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Narayanan Rajendran, Shu-Chieh Hu, Dennis Sullivan, Miguel Muzzio, Carol J. Detrisac & Carmen Venezia. (2012) Toxicologic evaluation of tungsten: 28-day inhalation study of tungsten blue oxide in rats. Inhalation Toxicology 24:14, pages 985-994.
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KiSoo Jeon, Il Je Yu & Kang-Ho Ahn. (2012) Evaluation of newly developed nose-only inhalation exposure chamber for nanoparticles. Inhalation Toxicology 24:9, pages 550-556.
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Biswadip Sinha & Biswajit Mukherjee. (2012) Development of an inhalation chamber and a dry powder inhaler device for administration of pulmonary medication in animal model. Drug Development and Industrial Pharmacy 38:2, pages 171-179.
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D.M. Bernstein, R.A. Rogers, R. Sepulveda, K. Donaldson, D. Schuler, S. Gaering, P. Kunzendorf, J. Chevalier & S.E. Holm. (2011) Quantification of the pathological response and fate in the lung and pleura of chrysotile in combination with fine particles compared to amosite-asbestos following short-term inhalation exposure. Inhalation Toxicology 23:7, pages 372-391.
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D. M. Bernstein, R. A. Rogers, R. Sepulveda, K. Donaldson, D. Schuler, S. Gaering, P. Kunzendorf , J. Chevalier & S. E. Holm. (2010) The pathological response and fate in the lung and pleura of chrysotile in combination with fine particles compared to amosite asbestos following short-term inhalation exposure: interim results. Inhalation Toxicology 22:11, pages 937-962.
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D. M. Bernstein, K. Donaldson, U. Decker, S. Gaering, P. Kunzendorf, J. Chevalier & S. E. Holm. (2008) A Biopersistence Study following Exposure to Chrysotile Asbestos Alone or in Combination with Fine Particles. Inhalation Toxicology 20:11, pages 1009-1028.
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Charles L. Gaworski, Christopher R. E. Coggins & Edward L. Carmines. (2008) Palladium Alters Cigarette Smoke Toxicological Profile, but Accumulates in the Lungs of Rats During Inhalation Exposure. Inhalation Toxicology 20:2, pages 167-182.
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Kimberly C. Hodge-Bell, K. Monica Lee, Roger A. Renne, Kathy M. Gideon, Sam J. Harbo & Willie J. McKinney. (2007) Pulmonary Inflammation in Mice Exposed to Mainstream Cigarette Smoke. Inhalation Toxicology 19:4, pages 361-376.
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O. R. Moss, R. A. James & B. Asgharian. (2006) Influence of Exhaled Air on Inhalation Exposure Delivered Through a Directed-Flow Nose-Only Exposure System. Inhalation Toxicology 18:1, pages 45-51.
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David M. Bernstein, Rick Rogers & Paul Smith. (2004) The Biopersistence of Brazilian Chrysotile Asbestos Following Inhalation. Inhalation Toxicology 16:11-12, pages 745-761.
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David M. Bernstein, Jörg Chevalier & Paul Smith. (2003) Comparison of Calidria Chrysotile Asbestos to Pure Tremolite: Inhalation Biopersistence and Histopathology Following Short-Term Exposure. Inhalation Toxicology 15:14, pages 1387-1419.
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David M. Bernstein, Rick Rogers & Paul Smith. (2003) The Biopersistence of Canadian Chrysotile Asbestos Following Inhalation. Inhalation Toxicology 15:13, pages 1247-1274.
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David C. Dorman, Karrie A. Brenneman, Anna M. McElveen, Sean E. Lynch, Kay C. Roberts & Brian A. Wong. (2002) OLFACTORY TRANSPORT: A DIRECT ROUTE OF DELIVERY OF INHALED MANGANESE PHOSPHATE TO THE RAT BRAIN. Journal of Toxicology and Environmental Health, Part A 65:20, pages 1493-1511.
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E. E. McConnell, C. Axten, T. W. Hesterberg, J. Chevalier, W. C. Miiller, J. Everitt, G. Oberdorster, G. R. Chase, P. Thevenaz & P. Kotin. (1999) STUDIES ON THE INHALATION TOXICOLOGY OF TWO FIBERGLASSES AND AMOSITE ASBESTOS IN THE SYRIAN GOLDEN HAMSTER. PART II. RESULTS OF CHRONIC EXPOSURE. Inhalation Toxicology 11:9, pages 785-835.
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T. W. Hesterberg, C. Axten, E. E. McConnell, G. A. Hart, W. Miiller, J. Chevalier, J. Everitt, P. Thevenaz & G. Oberdorster. (1999) STUDIES ON THE INHALATION TOXICOLOGY OF TWO FIBERGLASSES AND AMOSITE ASBESTOS IN THE SYRIAN GOLDEN HAMSTER. PART I. RESULTS OF A SUBCHRONIC STUDY AND DOSE SELECTION FOR A CHRONIC STUDY. Inhalation Toxicology 11:9, pages 747-784.
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Allen D. Ledbetter Paul M. Killough George F. Hudson. (1998) A LOW-SAMPLE-CONSUMPTION DRY-PARTICULATE AEROSOL GENERATOR FOR USE IN NOSE-ONLY INHALATION EXPOSURES. Inhalation Toxicology 10:3, pages 239-251.
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David M. Bernstein, Charles Morscheidt, Hans-Günther Grimm, Philippe Thévenaz & Ullrich Teichert. (1996) Evaluation of Soluble fibers Using the Inhalation Biopersistence Model, a Nine-fiber Comparison. Inhalation Toxicology 8:4, pages 345-385.
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David R. Hemenway, Robert Clarke, Robert Frank & George J. Jakab. (1996) Factors Governing the Mass Loading of Aerosolized Carbon Black Particles with Acid Sulfates, Inhalation Exposure, and Alveolar Macrophage Phagocytic Function. Inhalation Toxicology 8:7, pages 679-694.
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David C. Dorman, Brian A. Wong, Melanie F. Struve, R. Arden James, Krista M. D. Laperle, Marianne Marshall & Brad Bolon. (1996) Development of a Mouse Whole-Body Exposure System from a Directed-Flow, Rat Nose-Only System. Inhalation Toxicology 8:1, pages 107-120.
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Yung-Sung Cheng & Owen R. Moss. (1995) Inhalation Exposure Systems. Toxicology Methods 5:3, pages 161-197.
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E. E. McConnell, R. W. Mast, T. W. Hesterberg, J. Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass & R. Anderson. (1995) Chronic Inhalation Toxicity of a Kaolin-Based Refractory Ceramic Fiber in Syrian Golden Hamsters. Inhalation Toxicology 7:4, pages 503-532.
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R. W. Mast, E. E. McConnell, T. W. Hesterberg, J. Chevalier, P. Kotin, P. Thevenaz, D. M. Bernstein, L. R. Glass, W. Miiller & R. Anderson. (1995) Multiple-Dose Chronic Inhalation Toxicity Study of Size-Separated Kaolin Refractory Ceramic Fiber in Male Fischer 344 Rats. Inhalation Toxicology 7:4, pages 469-502.
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R. W. Mast, E. E. McConnell, R. Anderson, J Chevalier, P. Kotin, D. M. Bernstein, P. Thevenaz, L. R. Glass, W. C. Miiller & T. W. Hesterberg. (1995) Studies on the Chronic Toxicity (Inhalation) Of Four Types of Refractory Ceramic Fiber in Male Fischer 344 Rats. Inhalation Toxicology 7:4, pages 425-467.
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David M. Bernstein, Charles Morscheidt, Hartmut Tiesler, Hans-Günther Grimm, Philippe Thévenaz & Ullrich Teichert. (1995) Evaluation of the Biopersistence of Commercial and Experimental Fibers Following Inhalation. Inhalation Toxicology 7:7, pages 1031-1058.
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E. E. McConnell, O. Kamstrup, R. Musselman, T. W. Hesterberg, J. Chevalier, W. C. Miiller & P. Thevenaz. (1994) Chronic Inhalation Study of Size-Separated Rock and Slag Wool Insulation Fibers in Fischer 344/N Rats. Inhalation Toxicology 6:6, pages 571-614.
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R K. Wolff & M. A. Dorato. (1993) Toxicologic Testing of Inhaled Pharmaceutical Aerosols. Critical Reviews in Toxicology 23:4, pages 343-369.
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R. A. Renne, A. P. Wehner, B. J. Greenspan, H. S. Deford, H. A. Ragan, R. B. Westerberg, R. L. Buschbom, G. T. Burger, A. W. Hayes, R. L. Suber & A. T. Mosberg. (1992) 2-Week and 13-Week Inhalation Studies of Aerosolized Glycerol in Rats. Inhalation Toxicology 4:2, pages 95-111.
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H. G. Folkesson, B. R. Weström, M. Dahlbäck, S. Lundin & B. W. Karlsson. (1992) Passage of Aerosolized BSA and the Nona-peptide dDAVP via the Respiratory Tract in Young and Adult Rats. Experimental Lung Research 18:5, pages 595-614.
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David R. R. Hernenway, George J. Jakab, Terence H. Risby, Shelley S. Sehnert, Stephen M. Bowes & Robert Hrnieleski. (1990) Nose-Only Inhalation System Using the Fluidized-Bed Generation System for Coexposures to Carbon Black and Formaldehyde. Inhalation Toxicology 2:1, pages 69-89.
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Paul H. Ayres, Arnold T. Mosberg, Gary T. Burger, A. Wallace Hayes, John W. Sagartz & Christopher R. E. Coggins. (1989) Nose-Only Exposure of Rats to Carbon Monoxide. Inhalation Toxicology 1:4, pages 349-363.
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