Advanced search
Publication Cover
Toxicology Mechanisms and Methods Volume 28, 2018 - Issue 5
Submit an article Journal homepage
360
Views
21
CrossRef citations to date
0
Altmetric
Research Article

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats

Joylee FernandesDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India;
,
Jayesh MudgalDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India; ORCID Iconhttp://orcid.org/0000-0001-8190-7031
ORCID Icon,
Chamallamudi Mallikarjuna RaoDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India; ORCID Iconhttp://orcid.org/0000-0002-9654-2028
ORCID Icon,
Devinder AroraDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India; ;School of Pharmacy, MHIQ, QUM Network, Griffith University, Goldcoast, Australia
,
Sanchari Basu MallikDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India; ORCID Iconhttp://orcid.org/0000-0002-5357-4150
ORCID Icon,
K. S. R. PaiDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India; ORCID Iconhttp://orcid.org/0000-0002-2017-9533
ORCID Icon &
Madhavan NampoothiriDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-2218-2004
ORCID Icon show all
Pages 328-334 | Received 17 Aug 2017, Accepted 25 Nov 2017, Published online: 08 Jan 2018

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Prasada Chowdari Gurram, Sairaj Satarker, Gautam Kumar, Farmiza Begum, Chetan Mehta, Usha Nayak, Jayesh Mudgal, Devinder Arora & Madhavan Nampoothiri. (2023) Avanafil mediated dual inhibition of IKKβ and TNFR1 in an experimental paradigm of Alzheimer’s disease: in silico and in vivo approach. Journal of Biomolecular Structure and Dynamics 41:20, pages 10659-10677.
Read now
Yu-Jia Liu, Tian-Tian Liu, Lin-Hao Jiang, Qian Liu, Zheng-Liang Ma, Tian-Jiao Xia & Xiao-Ping Gu. (2021) Identification of hub genes associated with cognition in the hippocampus of Alzheimer’s Disease. Bioengineered 12:2, pages 9598-9609.
Read now
Samita Rijal, Nilanjan Changdar, Manas Kinra, Ayush Kumar, Madhavan Nampoothiri, Devinder Arora, Rekha R. Shenoy, K. Sreedhara Ranganath Pai, Alex Joseph & Jayesh Mudgal. (2019) Neuromodulatory potential of phenylpropanoids; para-methoxycinnamic acid and ethyl-p-methoxycinnamate on aluminum-induced memory deficit in rats. Toxicology Mechanisms and Methods 29:5, pages 334-343.
Read now

Articles from other publishers (18)

Pratibha Kumari, Ravi Kumar, Darshana Singh & Raj Kumar. (2023) N-acetyl-L-tryptophan (NAT) provides protection to intestinal epithelial cells (IEC-6) against radiation-induced apoptosis via modulation of oxidative stress and mitochondrial membrane integrity. Molecular Biology Reports 50:8, pages 6381-6397.
Crossref
Prasada Chowdari Gurram, Suman Manandhar, Sairaj Satarker, Jayesh Mudgal, Devinder Arora & Madhavan Nampoothiri. (2023) Dopaminergic Signaling as a Plausible Modulator of Astrocytic Toll-Like Receptor 4: A Crosstalk between Neuroinflammation and Cognition. CNS & Neurological Disorders - Drug Targets 22:4, pages 539-557.
Crossref
Rachagolla Sai Prathap YadavBelle Vijetha ShenoyNitesh KumarG Prasanna KumarS Naveen Kumar. (2023) In vivo Acetylcholinesterase activity and Antioxidant property of Cucurbita pepo ethanolic extract in Alzheimer’s disease induced by Aluminium chloride in Sprague Dawley rat model. Research Journal of Pharmacy and Technology, pages 1065-1071.
Crossref
Devasrita Dash, Laxminarayana Bairy Kurady & Bharti Chogtu. (2022) Effect of Vildagliptin on Cognitive Deficits in an Experimental Model of Alzheimer’s Disease. Biomedical and Pharmacology Journal 15:3, pages 1261-1270.
Crossref
Mangaldeep Dey & Rakesh Kumar Singh. (2022) Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer’s disease. Pharmacological Reports 74:3, pages 439-450.
Crossref
Joanna Matalińska & Piotr F.J. Lipiński. (2022) Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor. Molecular and Cellular Neuroscience 120, pages 103728.
Crossref
Safieh Ebrahimi, Abbas Alalikhan, Seyed Hamid Aghaee-Bakhtiari & Seyed Isaac Hashemy. (2022) The redox modulatory effects of SP/NK1R system: Implications for oxidative stress-associated disorders. Life Sciences 296, pages 120448.
Crossref
Sairaj Satarker, Sree Lalitha Bojja, Prasada Chowdari Gurram, Jayesh Mudgal, Devinder Arora & Madhavan Nampoothiri. (2022) Astrocytic Glutamatergic Transmission and Its Implications in Neurodegenerative Disorders. Cells 11:7, pages 1139.
Crossref
Sairaj Satarker, Swastika Maity, Jayesh Mudgal & Madhavan Nampoothiri. (2021) In silico screening of neurokinin receptor antagonists as a therapeutic strategy for neuroinflammation in Alzheimer’s disease. Molecular Diversity 26:1, pages 443-466.
Crossref
Urja Kanojia, Shrikant Gyaneshwar Chaturbhuj, Runali Sankhe, Maushami Das, Raviteja Surubhotla, Nandakumar Krishnadas, Karthik Gourishetti, Pawan Ganesh Nayak & Anoop Kishore. (2021) Beta-Caryophyllene, a CB2R Selective Agonist, Protects Against Cognitive Impairment Caused by Neuro-inflammation and Not in Dementia Due to Ageing Induced by Mitochondrial Dysfunction. CNS & Neurological Disorders - Drug Targets 20:10, pages 963-974.
Crossref
Anne-Christine Aust, Eliska Benesova, Veronika Vidova, Katerina Coufalikova, Sona Smetanova, Ivo Borek, Petr Janku, Eva Budinska, Jana Klanova, Vojtech Thon & Zdenek Spacil. (2021) Profiling Tryptophan Catabolites of Human Gut Microbiota and Acute-Phase Protein Levels in Neonatal Dried Blood Specimens. Frontiers in Microbiology 12.
Crossref
Chong-Sun Khoi, Jia-Huang Chen, Tzu-Yu Lin, Chih-Kang Chiang & Kuan-Yu Hung. (2021) Ochratoxin A-Induced Nephrotoxicity: Up-to-Date Evidence. International Journal of Molecular Sciences 22:20, pages 11237.
Crossref
Sairaj Satarker & Madhavan Nampoothiri. (2020) Involvement of the nervous system in COVID-19: The bell should toll in the brain. Life Sciences 262, pages 118568.
Crossref
Vignesh Balaji E, Nitesh Kumar, Sairaj Satarker & Madhavan Nampoothiri. (2020) Zinc as a plausible epigenetic modulator of glioblastoma multiforme. European Journal of Pharmacology 887, pages 173549.
Crossref
Indrani Ghosh, Runali Sankhe, Jayesh Mudgal, Devinder Arora & Madhavan Nampoothiri. (2020) Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders. Neuropeptides 83, pages 102083.
Crossref
Prasanth M. Eapen, Chamallamudi Mallikarjuna Rao & Madhavan Nampoothiri. (2019) Crosstalk between neurokinin receptor signaling and neuroinflammation in neurological disorders. Reviews in the Neurosciences 30:3, pages 233-243.
Crossref
Ninghua Huang, Bing Cao, Elisa Brietzke, Caroline Park, Danielle Cha, Zihang Pan, Judy Zhu, Yaqiong Liu, Qing Xie, Jing Zeng, Roger S. McIntyre, Jingyu Wang & Lailai Yan. (2019) A pilot case-control study on the association between N-acetyl derivatives in serum and first-episode schizophrenia. Psychiatry Research 272, pages 36-41.
Crossref
Xin-Yi Chen, Yi-Feng Du & Lei Chen. (2019) Neuropeptides Exert Neuroprotective Effects in Alzheimer's Disease. Frontiers in Molecular Neuroscience 11.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.