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COPD: Journal of Chronic Obstructive Pulmonary Disease Volume 2, 2005 - Issue 3
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Basic Review

The Role of Airway Secretions in COPD: Pathophysiology, Epidemiology and Pharmacotherapeutic Options

Dr. Duncan F. Rogers National Heart & Lung Institute, Imperial College, London, Dovehouse St., London, SW3 6LY, UKCorrespondence[email protected]
Pages 341-353 | Published online: 02 Jul 2009

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Donald P Tashkin, Ayca Ozol-Godfrey, Sanjay Sharma & Shahin Sanjar. (2021) Effect of SGRQ-Defined Chronic Bronchitis at Baseline on Treatment Outcomes in Patients with COPD Receiving Nebulized Glycopyrrolate. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 945-955.
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Ye Liu, Jingxuan Zhu, Xiaoqing Guo, Tianci Huang, Jiarui Han, Jianjiong Gao, Dong Xu & Weiwei Han. (2020) How oncogenic mutations activate human MAP kinase 1 (MEK1): a molecular dynamics simulation study. Journal of Biomolecular Structure and Dynamics 38:13, pages 3942-3958.
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Steve Price. (2008) Putative allosteric MEK1 and MEK2 inhibitors. Expert Opinion on Therapeutic Patents 18:6, pages 603-627.
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Andrew J Thorley & Teresa D Tetley. (2007) Pulmonary epithelium, cigarette smoke, and chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease 2:4, pages 409-428.
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Duncan F. Rogers & Peter J. Barnes. (2006) Treatment of airway mucus hypersecretion. Annals of Medicine 38:2, pages 116-125.
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Articles from other publishers (20)

Efthymia Papadopoulou, Jan Hansel, Zsofia Lazar, Konstantinos Kostikas, Stavros Tryfon, Jørgen Vestbo & Alexander G. Mathioudakis. (2023) Mucolytics for acute exacerbations of chronic obstructive pulmonary disease: a meta-analysis. European Respiratory Review 32:167, pages 220141.
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Stefano Castellani, Adriana Trapani, Giovanna Elisiana Carpagnano, Antonella Cotoia, Onofrio Laselva, Maria Pia Foschino Barbaro, Filomena Corbo, Gilda Cinnella, Elvira De Giglio, Domenico Larobina, Sante Di Gioia & Massimo Conese. (2022) Mucopenetration study of solid lipid nanoparticles containing magneto sensitive iron oxide. European Journal of Pharmaceutics and Biopharmaceutics 178, pages 94-104.
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Parvarish Sharma, Daljeet Singh Dhanjal, Chirag Chopra, Murtaza M. Tambuwala, Sukhwinder Singh Sohal, Peter J. van der Spek, Hari S. Sharma & Saurabh Satija. (2022) Targeting eosinophils in chronic respiratory diseases using nanotechnology-based drug delivery. Chemico-Biological Interactions 365, pages 110050.
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Pınar MUTLU, Nilüfer AYLANÇ, N.arzu MİRİCİ & Merve İLÇİN GÜVEN. (2020) KRONİK OBSTRÜKTİF AKCİĞER HASTALIĞINDA FENOTİPLERE GÖRE KAN BİYOBELİRTEÇLERİNİN KARŞILAŞTIRILMASICOMPARISON OF BLOOD BIOMARKERS WITH PHENOTYPES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Sağlık Bilimleri Dergisi 29:1, pages 46-50.
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Casandra L. Hoffman, Jonathan Lalsiamthara & Alejandro Aballay. (2020) Host Mucin Is Exploited by Pseudomonas aeruginosa To Provide Monosaccharides Required for a Successful Infection. mBio 11:2.
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Sheng-Wei Chang, Jack Wellmerling, Xiaoli Zhang, Rachael E. Rayner, Wissam Osman, Sara Mertz, Amal O. Amer, Mark E. Peeples, Prosper N. Boyaka & Estelle Cormet-Boyaka. (2018) The psychoactive substance of cannabis Δ9-tetrahydrocannabinol (THC) negatively regulates CFTR in airway cells. Biochimica et Biophysica Acta (BBA) - General Subjects 1862:9, pages 1988-1994.
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Chad H. Hochberg & Venkataramana K. Sidhaye. 2017. Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease. Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease 165 184 .
Michelle Lisidati Franchini, Rodrigo Athanazio, Luis Fernando Amato-Lourenço, Waldir Carreirão-Neto, Paulo Hilario Nascimento Saldiva, Geraldo Lorenzi-Filho, Bruce K. Rubin & Naomi Kondo Nakagawa. (2016) Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function. CHEST 150:2, pages 407-414.
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Ling-tian Ge, Ya-nan Liu, Xi-xi Lin, Hui-juan Shen, Yong-liang Jia, Xin-wei Dong, Yun Sun & Qiang-min Xie. (2016) Inhalation of ambroxol inhibits cigarette smoke-induced acute lung injury in a mouse model by inhibiting the Erk pathway. International Immunopharmacology 33, pages 90-98.
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Emily V.S. Ha & Duncan F. Rogers. (2016) Novel Therapies to Inhibit Mucus Synthesis and Secretion in Airway Hypersecretory Diseases. Pharmacology 97:1-2, pages 84-100.
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Wei Du, Jinyu Su, Dan Ye, Yuegang Wang, Qiaobing Huang & Xiaowei Gong. (2016) Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after Inhaled Corticosteroid Withdrawal in COPD Rats . The American Journal of Chinese Medicine 44:05, pages 1027-1041.
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Monica Berry & Anthony Corfield. 2014. Mucoadhesive Materials and Drug Delivery Systems. Mucoadhesive Materials and Drug Delivery Systems 133 158 .
Yoo Kuen Chan. 2014. Airway Management. Airway Management 1 14 .
Jos? Luis Izquierdo-Alonso, Jose Miguel Rodriguez-Gonz?lezMoro, Pilar de Lucas-Ramos, Irune Unzueta, Xabier Ribera, Esther Ant?n & Antonio Mart?n. (2013) Prevalence and characteristics of three clinical phenotypes of chronic obstructive pulmonary disease (COPD). Respiratory Medicine 107:5, pages 724-731.
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Haiqiao Wu, Qi Li, Xiangdong Zhou, Victor P. Kolosov & Juliy M. Perelman. (2011) Theaflavins Extracted from Black Tea Inhibit Airway Mucous Hypersecretion Induced by Cigarette Smoke in Rats. Inflammation 35:1, pages 271-279.
Crossref
Qi Li, Xiangdong Zhou, Victor P. Kolosov & Juliy M. Perelman. (2010) Nicotine suppresses inflammatory factors in HBE16 airway epithelial cells after exposure to cigarette smoke extract and lipopolysaccharide. Translational Research 156:6, pages 326-334.
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David R. Curran & Lauren Cohn. (2010) Advances in Mucous Cell Metaplasia. American Journal of Respiratory Cell and Molecular Biology 42:3, pages 268-275.
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Katharine H Banner & Neil J Press. (2009) Dual PDE3/4 inhibitors as therapeutic agents for chronic obstructive pulmonary disease. British Journal of Pharmacology 157:6, pages 892-906.
Crossref
Peter J. Barnes & Stephen I. Rennard. 2009. Asthma and COPD. Asthma and COPD 425 442 .
Duncan F. Rogers. 2009. Asthma and COPD. Asthma and COPD 211 223 .

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