685
Views
34
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

N-Acetylcysteine and Exacerbations of Chronic Obstructive Pulmonary Disease

, &
Pages 195-202 | Published online: 02 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Zheng Zeng, Dan Yang, Xiaoling Huang & Zhenliang Xiao. (2017) Effect of carbocisteine on patients with COPD: a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease 12, pages 2277-2283.
Read now
Kara Johnson, Charlene E McEvoy, Sakina Naqvi, Chris Wendt, Ronald A Reilkoff, Ken M Kunisaki, Erin E Wetherbee, David Nelson, Rabindra Tirouvanziam & Dennis E Niewoehner. (2016) High-dose oral N-acetylcysteine fails to improve respiratory health status in patients with chronic obstructive pulmonary disease and chronic bronchitis: a randomized, placebo-controlled trial. International Journal of Chronic Obstructive Pulmonary Disease 11, pages 799-807.
Read now
Jia-Qiang Zhang, Jian-Qing Zhang, Li-Zhou Fang, Ling Liu, Wei-Ping Fu & Lu-Ming Dai. (2015) Effect of oral N-acetylcysteine on COPD patients with microsatellite polymorphism in the heme oxygenase-1 gene promoter. Drug Design, Development and Therapy 9, pages 6379-6387.
Read now
Jian-Qing Zhang, Jia-Qiang Zhang, Hua Liu, Zhi-Huan Zhao, Li-Zhou Fang, Ling Liu, Wei-Ping Fu, Jing-Kui Shu, Jia-Gang Feng & Lu-Ming Dai. (2015) Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes. International Journal of Chronic Obstructive Pulmonary Disease 10, pages 917-923.
Read now
Pierachille Santus, Angelo Corsico, Paolo Solidoro, Fulvio Braido, Fabiano Di Marco & Nicola Scichilone. (2014) Oxidative Stress and Respiratory System: Pharmacological and Clinical Reappraisal of N-Acetylcysteine. COPD: Journal of Chronic Obstructive Pulmonary Disease 11:6, pages 705-717.
Read now
Yanfei Shen, Wanru Cai, Shu Lei & Zhongheng Zhang. (2014) Effect of High/Low Dose N-Acetylcysteine on Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis. COPD: Journal of Chronic Obstructive Pulmonary Disease 11:3, pages 351-358.
Read now
Michael E. Nicks, Maureen M. O'Brien & Russell P. Bowler. (2011) Plasma Antioxidants Are Associated with Impaired Lung Function and COPD Exacerbations in Smokers. COPD: Journal of Chronic Obstructive Pulmonary Disease 8:4, pages 264-269.
Read now
Jiun-Lih Lin & Paul S. Thomas. (2010) Current Perspectives of Oxidative Stress and its Measurement in Chronic Obstructive Pulmonary Disease. COPD: Journal of Chronic Obstructive Pulmonary Disease 7:4, pages 291-306.
Read now
Noora Louhelainen, Marjukka Myllärniemi, Irfan Rahman & Vuokko L Kinnula. (2008) Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: Current and future perspectives. International Journal of Chronic Obstructive Pulmonary Disease 3:4, pages 585-603.
Read now

Articles from other publishers (25)

T. V. Tayutina. (2023) An integrated approach to the implementation of the stage of pulmonary rehabilitation of patients with chronic obstructive pulmonary disease: the importance of lifestyle modification. The Clinician 17:1, pages 28-38.
Crossref
Chienhsiu Huang, Sufang Kuo, Lichen Lin & Yalun Yang. (2023) The efficacy of N -acetylcysteine in chronic obstructive pulmonary disease patients: a meta-analysis . Therapeutic Advances in Respiratory Disease 17, pages 175346662311585.
Crossref
Yong Seok Jo, Ick Soo Choi & Yoon Kyoung So. (2021) The Use of Inhaled N-Acetylcysteine for Laryngopharyngeal Reflux Disease: A Randomized Controlled Trial. Journal of Voice 35:4, pages 618-624.
Crossref
Hidehiro Irie, Shotaro Chubachi, Minako Sato, Mamoru Sasaki, Naofumi Kameyama, Takashi Inoue, Yoshitaka Oyamada, Hidetoshi Nakamura, Koichiro Asano & Tomoko Betsuyaku. (2017) Impact of cataract on health-related quality of life in a longitudinal Japanese chronic obstructive pulmonary cohort. Chronic Respiratory Disease 15:4, pages 329-338.
Crossref
. (2017) Tratamiento de la EPOC Estable. Archivos de Bronconeumología 53, pages 23-33.
Crossref
Claudio M. Sanguinetti. (2016) N-acetylcysteine in COPD: why, how, and when?. Multidisciplinary Respiratory Medicine 11:1.
Crossref
Katharina Kranzer, Wael F Elamin, Helen Cox, James A Seddon, Nathan Ford & Francis Drobniewski. (2015) A systematic review and meta-analysis of the efficacy and safety of N -acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB . Thorax 70:11, pages 1070-1077.
Crossref
Mario Cazzola, Luigino Calzetta, Clive Page, Josè Jardim, Alexander G. Chuchalin, Paola Rogliani & Maria Gabriella Matera. (2015) Influence of N -acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis . European Respiratory Review 24:137, pages 451-461.
Crossref
Zeynep Ayfer Aytemur, Aysegul Baysak, Ozer Ozdemir, Timur Köse & Abdullah Sayiner. (2015) N-acetylcysteine in patients with COPD exacerbations associated with increased sputumN-Acetylcystein bei Patienten mit Exazerbation einer COPD mit erhöhter Sputumproduktion. Wiener klinische Wochenschrift 127:7-8, pages 256-261.
Crossref
Mario Cazzola & Maria Gabriella Matera. (2014) N-acetylcysteine in COPD may be beneficial, but for whom?. The Lancet Respiratory Medicine 2:3, pages 166-167.
Crossref
Qi Zhang, Jiun-Lih Lin & Paul S. Thomas. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants 1643 1670 .
Thomas E. Sussan & Shyam Biswal. 2014. Studies on Respiratory Disorders. Studies on Respiratory Disorders 335 348 .
Ahmed Mahmoud Abd El Hafiz, Lamia Mohammed El Wakeel, Hend Mohammed El Hady & Abd El Raheem Mourad. (2013) High dose N-acetyl cysteine improves inflammatory response and outcome in patients with COPD exacerbations. Egyptian Journal of Chest Diseases and Tuberculosis 62:1, pages 51-57.
Crossref
. (2012) Anexo 2 Preguntas respondidas por la UETS en la GPC para el tratamiento de pacientes con EPOC. Archivos de Bronconeumología 48, pages 61-80.
Crossref
. (2012) Guía de Práctica Clínica para el Diagnóstico y Tratamiento de Pacientes con Enfermedad Pulmonar Obstructiva Crónica (EPOC) - Guía Española de la EPOC (GesEPOC). Archivos de Bronconeumología 48, pages 2-58.
Crossref
Istvan Szelenyi. (2011) Nanomedicine: evolutionary and revolutionary developments in the treatment of certain inflammatory diseases. Inflammation Research 61:1, pages 1-9.
Crossref
Shiwan K. Shah, Shawn P. E. Nishi & Gulshan Sharma. 2012. Aging and Lung Disease. Aging and Lung Disease 63 87 .
Timothy E. Albertson, Kelly P. Owen, Mark E. Sutter & Nicholas J. Kenyon. 2012. Bronchial Asthma. Bronchial Asthma 361 381 .
A. Cuvelier, D. Benhamou, B. Lamia & J.-F. Muir. (2010) Exacerbations de la bronchopneumopathie chronique obstructive. EMC - Pneumologie 7:2, pages 1-17.
Crossref
Tiffany R. Richens, Derek J. Linderman, Sarah A. Horstmann, Cherie Lambert, Yi-Qun Xiao, Robert L. Keith, Darren M. Boé, Konosuke Morimoto, Russell P. Bowler, Brian J. Day, William J. Janssen, Peter M. Henson & R. William Vandivier. (2009) Cigarette Smoke Impairs Clearance of Apoptotic Cells through Oxidant-dependent Activation of RhoA. American Journal of Respiratory and Critical Care Medicine 179:11, pages 1011-1021.
Crossref
I. V. Leshchenko. (2008) Drug therapy of stable chronic obstructive pulmonary disease. PULMONOLOGIYA:3, pages 73-82.
Crossref
Rivka Siden & Cary E. Johnson. (2008) Stability of a flavored formulation of acetylcysteine for oral administration. American Journal of Health-System Pharmacy 65:6, pages 558-561.
Crossref
Katri KoliMarjukka MyllärniemiJorma Keski-OjaVuokko L. Kinnula. (2008) Transforming Growth Factor- β Activation in the Lung: Focus on Fibrosis and Reactive Oxygen Species . Antioxidants & Redox Signaling 10:2, pages 333-342.
Crossref
Nicola A. Hanania & Amir Sharafkhaneh. (2007) Update on the Pharmacologic Therapy for Chronic Obstructive Pulmonary Disease. Clinics in Chest Medicine 28:3, pages 589-607.
Crossref
S. N. Avdeev. (2007) Reduction of exacerbations of COPD under long-term administration of N-acetylcysteine. PULMONOLOGIYA:2, pages 89-97.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.