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Research Article

Topical application of the anti-microbial chemical triclosan induces immunomodulatory responses through the S100A8/A9-TLR4 pathway

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Pages 50-59 | Received 22 Sep 2016, Accepted 03 Nov 2016, Published online: 25 Jan 2017

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Rachel Baur, Michael Kashon, Ewa Lukomska, Lisa M. Weatherly, Hillary L. Shane & Stacey E. Anderson. (2023) Exposure to the anti-microbial chemical triclosan disrupts keratinocyte function and skin integrity in a model of reconstructed human epidermis. Journal of Immunotoxicology 20:1.
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Stacey E. Anderson, Rachel Baur, Michael Kashon, Ewa Lukomska, Lisa Weatherly & Hillary L. Shane. (2020) Potential classification of chemical immunologic response based on gene expression profiles. Journal of Immunotoxicology 17:1, pages 122-134.
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Hillary L. Shane, Carrie M. Long & Stacey E. Anderson. (2019) Novel cutaneous mediators of chemical allergy. Journal of Immunotoxicology 16:1, pages 13-27.
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Articles from other publishers (16)

Stacey E. Anderson, Courtney E. W. Sulentic & Barbara L. F. Kaplan. 2003. Patty's Toxicology. Patty's Toxicology 1 55 .
Peng Yuan, Fengge Shen, Junqiang Zhang, Shaohu Ouyang, Yuming Chen, Wei Zou & Qixing Zhou. (2022) Triclosan Reprograms Immunometabolism and Activates the Inflammasome in Human Macrophages. Environmental Science & Technology 57:1, pages 428-439.
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Rachel Baur, Hillary L. Shane, Lisa M. Weatherly, Ewa Lukomska, Michael Kashon & Stacey E. Anderson. (2022) Exposure to the immunomodulatory chemical triclosan differentially impacts immune cell populations in the skin of haired (BALB/c) and hairless (SKH1) mice. Toxicology Reports 9, pages 1766-1776.
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Doerthe A. Andreae & Anna Nowak-Wegrzyn. 2022. Early Nutrition and Long-Term Health. Early Nutrition and Long-Term Health 153 188 .
Qingling Zhu, Junli Wang, Jingqiu Ma, Xiaoyang Sheng & Feng Li. (2021) Changes in inflammatory factors in the Brown Norway rat model of food allergy. BMC Immunology 22:1.
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Hillary L. Shane, Sreekumar Othumpangat, Nikki B. Marshall, Francoise Blachere, Ewa Lukomska, Lisa M. Weatherly, Rachel Baur, John D. Noti & Stacey E. Anderson. (2020) Topical exposure to triclosan inhibits Th1 immune responses and reduces T cells responding to influenza infection in mice. PLOS ONE 15:12, pages e0244436.
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Lisa M Weatherly, Hillary L Shane, Sherri A Friend, Ewa Lukomska, Rachel Baur & Stacey E Anderson. (2020) Topical Application of the Antimicrobial Agent Triclosan Induces NLRP3 Inflammasome Activation and Mitochondrial Dysfunction. Toxicological Sciences 176:1, pages 147-161.
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Stacey E Anderson, Lisa Weatherly & Hillary L Shane. (2019) Contribution of antimicrobials to the development of allergic disease. Current Opinion in Immunology 60, pages 91-95.
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Adeline Bataille, Christelle Le Gall-Ianotto, Emmanuelle Genin & Laurent Misery. (2019) Sensitive Skin: Lessons From Transcriptomic Studies. Frontiers in Medicine 6.
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Mohammad A. Alfhili & Myon-Hee Lee. (2019) Triclosan: An Update on Biochemical and Molecular Mechanisms. Oxidative Medicine and Cellular Longevity 2019, pages 1-28.
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Yining Jin, Harini Acharya, Devansh Acharya, Rick Jorgensen, Haoran Gao, James Secord, Perry Ng & Venugopal Gangur. (2019) Advances in Molecular Mechanisms of Wheat Allergenicity in Animal Models: A Comprehensive Review. Molecules 24:6, pages 1142.
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Max T. Aung, Kelly K. Ferguson, David E. Cantonwine, Kelly M. Bakulski, Bhramar Mukherjee, Rita Loch-Caruso, Thomas F. McElrath & John D. Meeker. (2019) Associations between maternal plasma measurements of inflammatory markers and urinary levels of phenols and parabens during pregnancy: A repeated measures study. Science of The Total Environment 650, pages 1131-1140.
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Julianne Skarha, Lidia Mínguez-Alarcón, Paige L. Williams, Tim I.M. Korevaar, Ralph A. de Poortere, Maarten A.C. Broeren, Jennifer B. Ford, Melissa Eliot, Russ Hauser & Joseph M. Braun. (2019) Cross-sectional associations between urinary triclosan and serum thyroid function biomarker concentrations in women. Environment International 122, pages 256-262.
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G. Bowatte, I. Markevych, M. Standl, S. C. Dharmage, S. Koletzko, I. Lehmann, C.-P. Bauer, T. Schikowski, A. von Berg, D. Berdel & J. Heinrich. (2018) Hygienic behavior and allergic sensitization in German adolescents. Allergy 73:9, pages 1915-1918.
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Dirk W. Lachenmeier. 2018. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions 289 295 .
Stacey E. Anderson & Hillary L. Shane. 2018. Immunotoxicity Testing. Immunotoxicity Testing 27 46 .