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Basic Brief Reports

The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis

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Pages 881-890 | Received 31 Oct 2014, Accepted 27 Apr 2015, Published online: 15 Jun 2015

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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Toshifumi Tomoda, Kun Yang & Akira Sawa. (2020) Neuronal Autophagy in Synaptic Functions and Psychiatric Disorders. Biological Psychiatry 87:9, pages 787-796.
Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
H. Mitoma, A. Buffo, F. Gelfo, X. Guell, E. Fucà, S. Kakei, J. Lee, M. Manto, L. Petrosini, A.G. Shaikh & J.D. Schmahmann. (2019) Consensus Paper. Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders. The Cerebellum 19:1, pages 131-153.
Crossref
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Crossref
Yan G Zhao & Hong Zhang. (2019) Core autophagy genes and human diseases. Current Opinion in Cell Biology 61, pages 117-125.
Crossref
Mitsuyo Maeda, Toshiyuki Seto, Chiho Kadono, Hideto Morimoto, Sachiho Kida, Mitsuo Suga, Motohiro Nakamura, Yosky Kataoka, Takashi Hamazaki & Haruo Shintaku. (2019) Autophagy in the Central Nervous System and Effects of Chloroquine in Mucopolysaccharidosis Type II Mice. International Journal of Molecular Sciences 20:23, pages 5829.
Crossref
Fumi Suomi & Thomas G. McWilliams. (2019) Autophagy in the mammalian nervous system: a primer for neuroscientists. Neuronal Signaling 3:3.
Crossref
Catherine Hong Huan Hor & Bor Luen Tang. (2019) Beta-propeller protein-associated neurodegeneration (BPAN) as a genetically simple model of multifaceted neuropathology resulting from defects in autophagy. Reviews in the Neurosciences 30:3, pages 261-277.
Crossref
Derek Marsh & Joanna M. Dragich. (2019) Autophagy in mammalian neurodevelopment and implications for childhood neurological disorders. Neuroscience Letters 697, pages 29-33.
Crossref
Juan Zhuang, Jun Lu, Xin Wang, Xinfeng Wang, Weicheng Hu, Fashui Hong, Xiang-xiang Zhao & Yuan-lin Zheng. (2019) Purple sweet potato color protects against high-fat diet-induced cognitive deficits through AMPK-mediated autophagy in mouse hippocampus. The Journal of Nutritional Biochemistry 65, pages 35-45.
Crossref
Qifa Li, Xuefei Wu, Xueyan Na, Biying Ge, Qiong Wu, Xuewen Guo, Michael Ntim, Yue Zhang, Yiping Sun, Jinyi Yang, Zhicheng Xiao, Jie Zhao & Shao Li. (2019) Impaired Cognitive Function and Altered Hippocampal Synaptic Plasticity in Mice Lacking Dermatan Sulfotransferase Chst14/D4st1. Frontiers in Molecular Neuroscience 12.
Crossref
Sonia Levi & Valeria Tiranti. (2019) Neurodegeneration with Brain Iron Accumulation Disorders: Valuable Models Aimed at Understanding the Pathogenesis of Iron Deposition. Pharmaceuticals 12:1, pages 27.
Crossref
Camilla Russo, Anna Ardissone, Elena Freri, Serena Gasperini, Marco Moscatelli, Giovanna Zorzi, Celeste Panteghini, Barbara Castellotti, Barbara Garavaglia, Nardo Nardocci & Luisa Chiapparini. (2019) Substantia Nigra Swelling and Dentate Nucleus T2 Hyperintensity May Be Early Magnetic Resonance Imaging Signs of β-Propeller Protein-Associated Neurodegeneration. Movement Disorders Clinical Practice 6:1, pages 51-56.
Crossref
Wan-Ting Liu, Qian Chen, Zhi-Jie Gao, Xin-Na Ji, Ke-Ming Xu & Yan-Yan Cao. (2018) A Novel WDR45 Mutation in a 9-Month-Old Male Infant with Epileptic Spasms. Chinese Medical Journal 131:24, pages 2991-2992.
Crossref
Birgit Michels, Hanna Zwaka, Ruth Bartels, Oleh Lushchak, Katrin FrankeThomas Endres, Markus Fendt, Inseon Song, May Bakr, Tuvshinjargal BudragchaaBernhard Westermann, Dushyant MishraClaire EschbachStefanie SchreyerAnnika LingnauCaroline Vahl, Marike HilkerRandolf MenzelThilo KähneVolkmar Leßmann, Alexander Dityatev, Ludger Wessjohann & Bertram Gerber. (2018) Memory enhancement by ferulic acid ester across species. Science Advances 4:10.
Crossref
Philip Seibler, Lena F Burbulla, Marija Dulovic, Simone Zittel, Johanne Heine, Thomas Schmidt, Franziska Rudolph, Ana Westenberger, Aleksandar Rakovic, Alexander Münchau, Dimitri Krainc & Christine Klein. (2018) Iron overload is accompanied by mitochondrial and lysosomal dysfunction in WDR45 mutant cells. Brain 141:10, pages 3052-3064.
Crossref
Baris Bingol. (2018) Autophagy and lysosomal pathways in nervous system disorders. Molecular and Cellular Neuroscience 91, pages 167-208.
Crossref
Aditi Kulkarni, Jessica Chen & Sandra Maday. (2018) Neuronal autophagy and intercellular regulation of homeostasis in the brain. Current Opinion in Neurobiology 51, pages 29-36.
Crossref
S. N. Suresh, Vijaya Verma, Shruthi Sateesh, James P. Clement & Ravi Manjithaya. (2018) Neurodegenerative diseases: model organisms, pathology and autophagy. Journal of Genetics 97:3, pages 679-701.
Crossref
Raffaella De Pace, Miguel Skirzewski, Markus Damme, Rafael Mattera, Jeffrey Mercurio, Arianne M. Foster, Loreto Cuitino, Michal Jarnik, Victoria Hoffmann, H. Douglas Morris, Tae-Un Han, Grazia M. S. Mancini, Andrés Buonanno & Juan S. Bonifacino. (2018) Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome. PLOS Genetics 14:4, pages e1007363.
Crossref
C. Tello, A. Darling, V. Lupo, B. Pérez-Dueñas & C. Espinós. (2018) On the complexity of clinical and molecular bases of neurodegeneration with brain iron accumulation. Clinical Genetics 93:4, pages 731-740.
Crossref
Abi Li, Sarah Wiethoff, Charles Arber, Henry Houlden, Tamas Revesz & Janice L. Holton. 2018. Developmental Neuropathology. Developmental Neuropathology 455 468 .
Ivano Di Meo & Valeria Tiranti. (2018) Classification and molecular pathogenesis of NBIA syndromes. European Journal of Paediatric Neurology 22:2, pages 272-284.
Crossref
Vineet Vinay Kulkarni & Sandra Maday. (2018) Compartment-specific dynamics and functions of autophagy in neurons. Developmental Neurobiology 78:3, pages 298-310.
Crossref
Louise O’Keefe & Donna Denton. (2018) Using Drosophila Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer’s Disease . BioMed Research International 2018, pages 1-14.
Crossref
Angeleen Fleming, Mariella Vicinanza, Maurizio Renna, Claudia Puri, Thomas Ricketts, Jens Füllgrabe, Ana Lopez, Sarah M. de Jager, Avraham Ashkenazi, Mariana Pavel, Floriana Licitra, Andrea Caricasole, Stephen P. Andrews, John Skidmore & David C. Rubinsztein. 2018. The Molecular and Cellular Basis of Neurodegenerative Diseases. The Molecular and Cellular Basis of Neurodegenerative Diseases 299 343 .
Ben Loos, Daniel J. Klionsky & Esther Wong. (2017) Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging. Progress in Neurobiology 156, pages 90-106.
Crossref
Irene Benito-Cuesta, Héctor Diez, Lara Ordoñez & Francisco Wandosell. (2017) Assessment of Autophagy in Neurons and Brain Tissue. Cells 6:3, pages 25.
Crossref
Elisa Fucà, Michela Guglielmotto, Enrica Boda, Ferdinando Rossi, Ketty Leto & Annalisa Buffo. (2017) Preventive motor training but not progenitor grafting ameliorates cerebellar ataxia and deregulated autophagy in tambaleante mice. Neurobiology of Disease 102, pages 49-59.
Crossref
Fiona M. Menzies, Angeleen Fleming, Andrea Caricasole, Carla F. Bento, Stephen P. Andrews, Avraham Ashkenazi, Jens Füllgrabe, Anne Jackson, Maria Jimenez Sanchez, Cansu Karabiyik, Floriana Licitra, Ana Lopez Ramirez, Mariana Pavel, Claudia Puri, Maurizio Renna, Thomas Ricketts, Lars Schlotawa, Mariella Vicinanza, Hyeran Won, Ye Zhu, John Skidmore & David C. Rubinsztein. (2017) Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities. Neuron 93:5, pages 1015-1034.
Crossref
Zhou-Guang Wang, Hao Li, Yan Huang, Rui Li, Xiao-Fan Wang, Li-Xia Yu, Xue-Qiang Guang, Lei Li, Hong-Yu Zhang, Ying-Zheng Zhao, Chunxiang Zhang, Xiao-Kun Li, Rong-Zhou Wu, Mao-Ping Chu & Jian Xiao. (2016) Nerve growth factor-induced Akt/mTOR activation protects the ischemic heart via restoring autophagic flux and attenuating ubiquitinated protein accumulation. Oncotarget 8:3, pages 5400-5413.
Crossref
Miao HeYuetong DingChen ChuJing TangQi XiaoZhen-Ge Luo. (2016) Autophagy induction stabilizes microtubules and promotes axon regeneration after spinal cord injury. Proceedings of the National Academy of Sciences 113:40, pages 11324-11329.
Crossref
Sandra Maday. (2016) Mechanisms of neuronal homeostasis: Autophagy in the axon. Brain Research 1649, pages 143-150.
Crossref
Darius Ebrahimi-Fakhari, Afshin Saffari, Lara Wahlster, Jenny Lu, Susan Byrne, Georg F. Hoffmann, Heinz Jungbluth & Mustafa Sahin. (2016) Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism. Brain 139:2, pages 317-337.
Crossref
Susanne A. Schneider. (2016) Neurodegeneration with Brain Iron Accumulation. Current Neurology and Neuroscience Reports 16:1.
Crossref

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