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Autophagy Volume 12, 2016 - Issue 10
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Basic Research Papers

TBC1D20 mediates autophagy as a key regulator of autophagosome maturation

D. J. SidjaninDepartment of Cell Biology, Neurobiology, and Anatomy, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USACorrespondence[email protected]
,
Anna K. ParkDepartment of Cell Biology, Neurobiology, and Anatomy, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
,
Adam RonchettiDepartment of Cell Biology, Neurobiology, and Anatomy, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
,
Jamaria MartinsMicrobiology and Molecular Genetics, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
&
William T. JacksonDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USACorrespondence[email protected]
Pages 1759-1775 | Received 29 Jul 2015, Accepted 01 Jun 2016, Published online: 03 Aug 2016

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Mark T. Handley. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 4355 4362 .
Anne Feldmann, Fazilet Bekbulat, Heike Huesmann, Sarah Ulbrich, Jörg Tatzelt, Christian Behl & Andreas Kern. (2017) The RAB GTPase RAB18 modulates macroautophagy and proteostasis. Biochemical and Biophysical Research Communications 486:3, pages 738-743.
Crossref
Mark T. Handley. 2017. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules 1 8 .

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