7,718
Views
41
CrossRef citations to date
0
Altmetric
Research Paper

Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation

ORCID Icon, , , , , ORCID Icon, , , , , , , , , , , ORCID Icon & show all
Pages 1917-1934 | Received 16 Apr 2018, Accepted 22 Feb 2019, Published online: 30 Mar 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Guang Lu, Hayden Weng Siong Tan, Tomas Schmauck-Medina, Liming Wang, Jiaqing Chen, Yik-Lam Cho, Kelie Chen, Jing-Zi Zhang, Weifeng He, Yihua Wu, Dajing Xia, Jing Zhou, Evandro F. Fang, Lei Fang, Wei Liu & Han-Ming Shen. (2022) WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP. Autophagy 18:12, pages 2865-2879.
Read now
Eugènia Almacellas, Joffrey Pelletier, Charles Day, Santiago Ambrosio, Albert Tauler & Caroline Mauvezin. (2021) Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability. Autophagy 17:3, pages 796-813.
Read now

Articles from other publishers (39)

Yaru Wang, Yue Sun, Feiran Wang, Hongyi Wang & Jing Hu. (2023) Ferroptosis induction via targeting metabolic alterations in triple-negative breast cancer. Biomedicine & Pharmacotherapy 169, pages 115866.
Crossref
MAA Mamun, Ying Liu, Yin-Ping Geng, Yi-Chao Zheng, Ya Gao, Jian-Gang Sun, Long-Fei Zhao, Li-Juan Zhao & Hong-Min Liu. (2023) Discovery of neddylation E2s inhibitors with therapeutic activity. Oncogenesis 12:1.
Crossref
Felipe J. Renna, Juliana H. Enriqué Steinberg, Claudio D. Gonzalez, Maria Manifava, Mariana S. Tadic, Tamara Orquera, Carolina V. Vecino, Alejandro Ropolo, Daniele Guardavaccaro, Mario Rossi, Nicholas T. Ktistakis & Maria I. Vaccaro. (2023) Ubiquitination Is a Novel Post-Translational Modification of VMP1 in Autophagy of Human Tumor Cells. International Journal of Molecular Sciences 24:16, pages 12981.
Crossref
Yumiko Watanabe-Yasuoka, Ayako Gotou, Shigeomi Shimizu & Toshihiro Sashihara. (2023) Lactiplantibacillus plantarum OLL2712 Induces Autophagy via MYD88 and Strengthens Tight Junction Integrity to Promote the Barrier Function in Intestinal Epithelial Cells. Nutrients 15:12, pages 2655.
Crossref
Ying Shan, Banyun Mao, Ying Jin, Yan You, Yongxue Wang, Keng Shen & Lei Li. (2023) Expression of DDB1 is associated with subtypes of epithelial ovarian cancer and predicts clinical outcomes. Tissue and Cell 82, pages 102072.
Crossref
Yu-Hsuan Chen, Han-Hsiun Chen, Won-Jing Wang, Hsin-Yi Chen, Wei-Syun Huang, Chien-Han Kao, Sin-Rong Lee, Nai Yang Yeat, Ruei-Liang Yan, Shu-Jou Chan, Kuen-Phon Wu & Ruey-Hwa Chen. (2023) TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation. Nature Communications 14:1.
Crossref
Jae‐man Song, Minji Kang, Seungha Lee, Jungho Kim, Sunha Park, Da‐ha Park, Sanghyeon Lee & Young Ho Suh. (2023) Deneddylating enzyme SENP8 regulates neuronal development . Journal of Neurochemistry 165:3, pages 348-361.
Crossref
Wei Wan, Chuying Qian, Qian Wang, Jin Li, Hongtao Zhang, Lei Wang, Maomao Pu, Yewei Huang, Zhengfu He, Tianhua Zhou, Han‐Ming Shen & Wei Liu. (2023) STING directly recruits WIPI2 for autophagosome formation during STING‐induced autophagy. The EMBO Journal 42:8.
Crossref
Chia-Yi Lin, Kuo-Yen Huang, Shih-Han KaoMing-Shiu LinChih-Chien LinShuenn-Chen YangWei-Chia ChungYa-Hsuan ChangRong-Jie Chein & Pan-Chyr Yang. (2023) Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response. Science Advances 9:14.
Crossref
Yuankai Wu, Hayden Weng Siong Tan, Jin-Yi Lin, Han-Ming Shen, Haihe Wang & Guang Lu. (2023) Molecular mechanisms of autophagy and implications in liver diseases. Liver Research 7:1, pages 56-70.
Crossref
Seung-Cheol Jee & Heesun Cheong. (2023) Autophagy/Mitophagy Regulated by Ubiquitination: A Promising Pathway in Cancer Therapeutics. Cancers 15:4, pages 1112.
Crossref
Peifeng Yu & Zhihua Hua. (2023) To Kill or to Be Killed: How Does the Battle between the UPS and Autophagy Maintain the Intracellular Homeostasis in Eukaryotes?. International Journal of Molecular Sciences 24:3, pages 2221.
Crossref
Satoru Kobayashi, Younghee Hahn, Brett Silverstein, Mandeep Singh, Adeline Fleitz, Jennifer Van, Hongling Chen & Qiangrong Liang. (2023) Lysosomal dysfunction in diabetic cardiomyopathy. Frontiers in Aging 4.
Crossref
Xiaoyan Zang, Jing Wang, Yuan Xia, Jianyong Li, Lijuan Chen, Yan Gu & Xuxing Shen. (2022) LncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma. Leukemia Research 123, pages 106967.
Crossref
Mohammed Almannai, Dana Marafi & Ayman W. El-Hattab. (2022) WIPI proteins: Biological functions and related syndromes. Frontiers in Molecular Neuroscience 15.
Crossref
Guang Lu, Yu Wang, Yin Shi, Zhe Zhang, Canhua Huang, Weifeng He, Chuang Wang & Han‐Ming Shen. (2022) Autophagy in health and disease: From molecular mechanisms to therapeutic target. MedComm 3:3.
Crossref
Eugenia Almacellas & Caroline Mauvezin. (2022) Emerging roles of mitotic autophagy. Journal of Cell Science 135:11.
Crossref
Yingying Wei, Zhihui Zhu, Hongtao Hu, Jiaqi Guan, Bo Yang & Huajun Zhao. (2022) Eupaformosanin induces apoptosis and ferroptosis through ubiquitination of mutant p53 in triple-negative breast cancer. European Journal of Pharmacology 924, pages 174970.
Crossref
Ada Nowosad & Arnaud Besson. (2022) Lysosomes at the Crossroads of Cell Metabolism, Cell Cycle, and Stemness. International Journal of Molecular Sciences 23:4, pages 2290.
Crossref
Xin He, Ainong Zhu, Jianguo Feng & Xiaobin Wang. (2021) Role of neddylation in neurological development and diseases. Biotechnology and Applied Biochemistry 69:1, pages 330-341.
Crossref
Dan Huang, Shiya Zheng, Zhuyuan Liu, Kongbo Zhu, Hong Zhi & Genshan Ma. (2022) Machine Learning Revealed Ferroptosis Features and a Novel Ferroptosis-Based Classification for Diagnosis in Acute Myocardial Infarction. Frontiers in Genetics 13.
Crossref
Siao Muk Cheng, Min‐Chieh Shieh, Tzu‐Yu Lin & Chun Hei Antonio Cheung. (2021) The “Dark Side” of autophagy on the maintenance of genome stability: Does it really exist during excessive activation?. Journal of Cellular Physiology 237:1, pages 178-188.
Crossref
María Ángeles Peinado, David Ovelleiro, María Luisa del Moral, Raquel Hernández, Esther Martínez-Lara, Eva Siles, José Rafael Pedrajas, María Luisa García-Martín, Carlos Caro, Sebastián Peralta, María Encarnación Morales, María Adolfina Ruiz & Santos Blanco. (2021) Biological Implications of a Stroke Therapy Based in Neuroglobin Hyaluronate Nanoparticles. Neuroprotective Role and Molecular Bases. International Journal of Molecular Sciences 23:1, pages 247.
Crossref
Rui Qiang, Zitong Zhao, Lu Tang, Qian Wang, Yanhong Wang & Qian Huang. (2021) Identification of 5 Hub Genes Related to the Early Diagnosis, Tumour Stage, and Poor Outcomes of Hepatitis B Virus-Related Hepatocellular Carcinoma by Bioinformatics Analysis. Computational and Mathematical Methods in Medicine 2021, pages 1-20.
Crossref
Jia Liang Sun-Wang, Alex Yarritu-Gallego, Saška Ivanova & Antonio Zorzano. (2021) The ubiquitin-proteasome system and autophagy: self-digestion for metabolic health. Trends in Endocrinology & Metabolism 32:8, pages 594-608.
Crossref
Ganglei Li, Tiesong Zhang, Kaiyuan Huang, Yu Zhu, Kangli Xu, Jun Gu, Sicong Huang, Chenjie Gu, Renya Zhan & Jian Shen. (2021) Long noncoding RNA GAS8-AS1: A novel biomarker in human diseases. Biomedicine & Pharmacotherapy 139, pages 111572.
Crossref
Pei-Jian Zhang, Meng-Dong Liu, Fang-Yong Fan & Ke-Xia Liu. (2021) A Study on Mesoporous Silica Loaded With Novel Photosensitizers HCE6 and Oxaliplatin for the Treatment of Cholangiocarcinoma. Frontiers in Oncology 11.
Crossref
Elena V. Sazonova, Gelina S. Kopeina, Evgeny N. Imyanitov & Boris Zhivotovsky. (2021) Platinum drugs and taxanes: can we overcome resistance?. Cell Death Discovery 7:1.
Crossref
Guang Lu, Liming Wang, Jing Zhou, Wei Liu & Han-Ming Shen. (2021) A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy. Trends in Cell Biology 31:6, pages 432-444.
Crossref
Yi-Chao Zheng, Yan-Jia Guo, Bo Wang, Chong Wang, M. A. A. Mamun, Ya Gao & Hong-Min Liu. (2021) Targeting neddylation E2s: a novel therapeutic strategy in cancer. Journal of Hematology & Oncology 14:1.
Crossref
Richard I. Odle, Oliver Florey, Nicholas T. Ktistakis & Simon J. Cook. (2021) CDK1, the Other ‘Master Regulator’ of Autophagy. Trends in Cell Biology 31:2, pages 95-107.
Crossref
Yikang Gong. (2021) Regulation of autophagy during mitosis. E3S Web of Conferences 271, pages 03051.
Crossref
Lian Gong, Yi Hu, Dong He, Yuxing Zhu, Liang Xiang, Mengqing Xiao, Ying Bao, Xiaoming Liu, Qinghai Zeng, Jianye Liu, Ming Zhou, Yanhong Zhou, Yaxin Cheng, Yeyu Zhang, Liping Deng, Rongrong Zhu, Hua Lan & Ke Cao. (2020) Ubiquitin ligase CHAF1B induces cisplatin resistance in lung adenocarcinoma by promoting NCOR2 degradation. Cancer Cell International 20:1.
Crossref
Jia Liang Sun-Wang, Saška Ivanova & Antonio Zorzano. (2020) The dialogue between the ubiquitin-proteasome system and autophagy: Implications in ageing. Ageing Research Reviews 64, pages 101203.
Crossref
Jiping Yao, Xue Liang, Yanning Liu & Min Zheng. (2020) Neddylation: A Versatile Pathway Takes on Chronic Liver Diseases. Frontiers in Medicine 7.
Crossref
Sang-Min Jang, Christophe E. Redon, Bhushan L. Thakur, Meriam K. Bahta & Mirit I. Aladjem. (2020) Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases. Experimental & Molecular Medicine 52:10, pages 1637-1651.
Crossref
Zhangyuan Yin, Hana Popelka, Yuchen Lei, Ying Yang & Daniel J. Klionsky. (2020) The Roles of Ubiquitin in Mediating Autophagy. Cells 9:9, pages 2025.
Crossref
Xu‐ze Li, Zi‐chen Wang, Yong Qiu, Shu‐xian Ma, Ling‐bing Meng, Wen‐hao Wu, Pei Zhang, Wei Yang, Wen‐ping Song & Lining Huang. (2020) Bioinformatics analysis and verification of gene targets for benign tracheal stenosis. Molecular Genetics & Genomic Medicine 8:6.
Crossref
Ruey-Hwa Chen, Yu-Hsuan Chen & Tzu-Yu Huang. (2019) Ubiquitin-mediated regulation of autophagy. Journal of Biomedical Science 26:1.
Crossref