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ORIGINAL ARTICLE

Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) trial

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Pages 82-86 | Published online: 10 Jul 2009

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Read on this site (11)

P. Penttilä, P. Bono, K. Peltola & F. Donskov. (2018) Hyponatremia associates with poor outcome in metastatic renal cell carcinoma patients treated with everolimus: prognostic impact. Acta Oncologica 57:11, pages 1580-1585.
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Francesc Formiga, David Chivite, Ariadna Brasé, Irene Petit, Rafael Moreno-Gonzalez, Jose Carlos Arévalo-Lorido & Xavier Corbella. (2018) Clinical characteristics and prognosis in patients with a first acute heart failure hospitalization according to admission hyponatremia. Acta Clinica Belgica 73:4, pages 281-286.
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Khalid Ali, Abdulhalik Workicho & Esayas Kebede Gudina. (2016) Hyponatremia in patients hospitalized with heart failure: a condition often overlooked in low-income settings. International Journal of General Medicine 9, pages 267-273.
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Robert G Bennett. (2014) Current treatments for acute heart failure: focus on serelaxin. Research Reports in Clinical Cardiology 5, pages 169-182.
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Joseph F Dasta, Jun R Chiong, Rudell Christian, Keith Friend, Melissa Lingohr-Smith, Jay Lin & Irving B Cassidy. (2012) Update on tolvaptan for the treatment of hyponatremia. Expert Review of Pharmacoeconomics & Outcomes Research 12:4, pages 399-410.
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Andrew Ambrosy, Steven R Goldsmith & Mihai Gheorghiade. (2011) Tolvaptan for the treatment of heart failure: a review of the literature. Expert Opinion on Pharmacotherapy 12:6, pages 961-976.
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Savina Nodari, Geoffrey T Jao & Jun R Chiong. (2010) Clinical utility of tolvaptan in the management of hyponatremia in heart failure patients. International Journal of Nephrology and Renovascular Disease 3, pages 51-60.
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Elaine Ku, Niloofar Nobakht & Vito M Campese. (2009) Lixivaptan: a novel vasopressin receptor antagonist. Expert Opinion on Investigational Drugs 18:5, pages 657-662.
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Jennifer E Ho & John R Teerlink. (2008) Role of tolvaptan in acute decompensated heart failure. Expert Review of Cardiovascular Therapy 6:5, pages 601-608.
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Gerasimos Filippatos & Magda Heras. (2007) Acute Cardiac Care: Subspecialty Accreditation ante Portas. Acute Cardiac Care 9:2, pages 67-68.
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Denny Suwanto, Ivana Purnama Dewi & Rosi Amrilla Fagi. (2022) Hyponatremia in heart failure: not just 135 to 145. Journal of Basic and Clinical Physiology and Pharmacology 33:4, pages 381-388.
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Nicolò Ghionzoli, Francesco Gentile, Anna Maria Del Franco, Vincenzo Castiglione, Alberto Aimo, Alberto Giannoni, Silvia Burchielli, Matteo Cameli, Michele Emdin & Giuseppe Vergaro. (2021) Current and emerging drug targets in heart failure treatment. Heart Failure Reviews 27:4, pages 1119-1136.
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Alessandro Peri, Dario Norello & Benedetta Fibbi. 2022. Hydro Saline Metabolism. Hydro Saline Metabolism 1 29 .
Benedetta Fibbi, Giada Marroncini, Cecilia Anceschi, Laura Naldi & Alessandro Peri. (2021) Hyponatremia and Oxidative Stress. Antioxidants 10:11, pages 1768.
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Jonathan Urbach & Steven R. Goldsmith. (2021) Vasopressin antagonism in heart failure: a review of the hemodynamic studies and major clinical trials. Therapeutic Advances in Cardiovascular Disease 15, pages 175394472097774.
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Tien M.H. Ng, Luanda P. Grazette, Michael W. Fong, Andrew J. Yoon, Mimi Lou, Allen Kuo, Rani Y. Upadhyay, Emily E. Han, Anilkumar Mehra & Uri Elkayam. (2020) Tolvaptan vs. furosemide‐based diuretic regimens in patients hospitalized for heart failure with hyponatremia (AQUA‐AHF). ESC Heart Failure 7:4, pages 1927-1934.
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Meaghan Lunney, Marinella Ruospo, Patrizia Natale, Robert R Quinn, Paul E Ronksley, Ioannis Konstantinidis, Suetonia C Palmer, Marcello Tonelli, Giovanni FM Strippoli & Pietro Ravani. (2020) Pharmacological interventions for heart failure in people with chronic kidney disease. Cochrane Database of Systematic Reviews 2020:2.
Crossref
Giada Marroncini, Benedetta Fibbi, Alice Errico, Cecilia Grappone, Mario Maggi & Alessandro Peri. (2019) Effects of low extracellular sodium on proliferation and invasive activity of cancer cells in vitro. Endocrine 67:2, pages 473-484.
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Juan José Diaztagle-Fernández, Walter Gabriel Chaves-Saltiago, John Jaime Sprockel-Díaz, Andrés David Acevedo-Velasco, Fredy Hernán Rodríguez-Benítez, Mario Fernando Benavides-Solarte, María Angélica Rodríguez-Niño, Álvaro José Villamizar-Quintero, Giovanna Botero-Jaramillo & Francy Liliana Plazas-Vargas. (2019) Asociación entre hiponatremia, mortalidad y estancia hospitalaria en pacientes con falla cardíaca descompensada. MedUNAB 22:3, pages 294-303.
Crossref
M.J. Broch Porcar, B. Rodríguez Cubillo, J.M. Domínguez-Roldán, L. Álvarez Rocha, M.Á. Ballesteros Sanz, M. Cervera Montes, M. Chico Fernández, J.H. de Gea García, P. Enríquez Giraudo, A. García de Lorenzo y Mateos, R. Gómez López, R. Guerrero Pavón, F. López Sánchez, J.A. Llompart-Pou, S. Lubillo Montenegro, Z. Molina Collado, P. Ramírez Galleymore, M. Riveiro Vilaboa, A. Sánchez Corral & M.E. Herrera-Gutiérrez. (2019) Practical document on the management of hyponatremia in critically ill patients. Medicina Intensiva (English Edition) 43:5, pages 302-316.
Crossref
M.J. Broch Porcar, B. Rodríguez Cubillo, J.M. Domínguez-Roldán, L. Álvarez Rocha, M.Á. Ballesteros Sanz, M. Cervera Montes, M. Chico Fernández, J.H. de Gea García, P. Enríquez Giraudo, A. García de Lorenzo y Mateos, R. Gómez López, R. Guerrero Pavón, F. López Sánchez, J.A. Llompart-Pou, S. Lubillo Montenegro, Z. Molina Collado, P. Ramírez Galleymore, M. Riveiro Vilaboa, A. Sánchez Corral & M.E. Herrera-Gutiérrez. (2019) Documento práctico del manejo de la hiponatremia en pacientes críticos. Medicina Intensiva 43:5, pages 302-316.
Crossref
Jinhui Wang, Weijian Zhou & Xiaoning Yin. (2018) Improvement of hyponatremia is associated with lower mortality risk in patients with acute decompensated heart failure: a meta-analysis of cohort studies. Heart Failure Reviews 24:2, pages 209-217.
Crossref
Francesc Formiga, David Chivite, Xavier Corbella, Alicia Conde-Martel, José Carlos Arévalo-Lorido, Joan Carles Trullàs, José Pérez Silvestre, Sara Carrascosa García, Luis Manzano & Manuel Montero-Pérez-Barquero. (2019) Influence of potassium levels on one-year outcomes in elderly patients with acute heart failure. European Journal of Internal Medicine 60, pages 24-30.
Crossref
Aoife Garrahy & Christopher J. Thompson. 2019. Encyclopedia of Endocrine Diseases. Encyclopedia of Endocrine Diseases 349 364 .
Tamrat Befekadu Abebe, Eyob Alemayehu Gebreyohannes, Yonas Getaye Tefera, Akshaya Srikanth Bhagavathula, Daniel Asfaw Erku, Sewunet Admasu Belachew, Begashaw Melaku Gebresillassie & Tadesse Melaku Abegaz. (2018) The prognosis of heart failure patients: Does sodium level play a significant role?. PLOS ONE 13:11, pages e0207242.
Crossref
Hesham R. Omar & Maya Guglin. (2018) Rise of first follow-up sodium in patients hospitalized with acute heart failure is associated with better outcomes. International Journal of Cardiology 269, pages 201-206.
Crossref
Francisco Herrera-Gómez, Diana Monge-Donaire, Carlos Ochoa-Sangrador, Juan Bustamante-Munguira, Eric Alamartine & F. Álvarez. (2018) Correction of Hyponatremia May Be a Treatment Stratification Biomarker: A Two-Stage Systematic Review and Meta-Analysis. Journal of Clinical Medicine 7:9, pages 262.
Crossref
Masaru Hiki, Takatoshi Kasai, Shoichiro Yatsu, Azusa Murata, Hiroki Matsumoto, Takao Kato, Shoko Suda, Tetsuro Miyazaki, Atsutoshi Takagi & Hiroyuki Daida. (2018) Relationship Between Serum Sodium Level Within the Low-Normal Range on Admission and Long-Term Clinical Outcomes in Patients with Acute Decompensated Heart Failure. International Heart Journal 59:5, pages 1052-1058.
Crossref
Jessica H. Huston, Robinson Ferre, Peter S. Pang, Ovidiu Chioncel, Javed Butler & Sean Collins. (2018) Optimal Endpoints of Acute Heart Failure Therapy. American Journal of Therapeutics 25:4, pages e465-e474.
Crossref
Evi V Nagler, Maria C Haller, Wim Van Biesen, Raymond Vanholder, Jonathan C Craig & Angela C Webster. (2018) Interventions for chronic non-hypovolaemic hypotonic hyponatraemia. Cochrane Database of Systematic Reviews 2018:6.
Crossref
Shuichi Kitada, Shohei Kikuchi, Takeshi Tsujino, Tohru Masuyama & Nobuyuki Ohte. (2018) The prognostic value of brain natriuretic peptide in patients with heart failure and left ventricular ejection fraction higher than 60%: a sub-analysis of the J-MELODIC study. ESC Heart Failure 5:1, pages 36-45.
Crossref
Shu Yang & Mark Goldin. (2018) Therapeutic Advances in Hyponatremia: Fluids, Diuretics, Vaptans, and More. American Journal of Therapeutics 25:1, pages e67-e72.
Crossref
E. Sbardella, A. M. Isidori, G. Arnaldi, M. Arosio, C. Barone, A. Benso, R. Berardi, G. Capasso, M. Caprio, F. Ceccato, G. Corona, S. Della Casa, L. De Nicola, M. Faustini-Fustini, E. Fiaccadori, L. Gesualdo, S. Gori, A. Lania, G. Mantovani, P. Menè, G. Parenti, C. Pinto, R. Pivonello, P. Razzore, G. Regolisti, C. Scaroni, F. Trepiccione, A. Lenzi & A. Peri. (2017) Approach to hyponatremia according to the clinical setting: Consensus statement from the Italian Society of Endocrinology (SIE), Italian Society of Nephrology (SIN), and Italian Association of Medical Oncology (AIOM). Journal of Endocrinological Investigation 41:1, pages 3-19.
Crossref
Jason Cobb & James L. Bailey. 2018. Ventricular-Assist Devices and Kidney Disease. Ventricular-Assist Devices and Kidney Disease 71 78 .
Luigi Mario Castello, Marco Baldrighi, Alice Panizza, Ettore Bartoli & Gian Carlo Avanzi. (2016) Efficacy and safety of two different tolvaptan doses in the treatment of hyponatremia in the Emergency Department. Internal and Emergency Medicine 12:7, pages 993-1001.
Crossref
Helbert Rondon-Berrios & Tomas Berl. (2017) Vasopressin Receptor Antagonists in Hyponatremia: Uses and Misuses. Frontiers in Medicine 4.
Crossref
Sunil Bhandari, Alessandro Peri, Iain Cranston, Rachael McCool, Alison Shaw, Julie Glanville, Larisa Petrakova & Karl O'Reilly. (2017) A systematic review of known interventions for the treatment of chronic nonhypovolaemic hypotonic hyponatraemia and a meta‐analysis of the vaptans. Clinical Endocrinology 86:6, pages 761-771.
Crossref
Antonio Pose, Luis Almenar, Juan José Gavira, Amador López-Granados, Teresa Blasco, Juan Delgado, Oscar Aramburu, Avelino Rodríguez, Luis Manzano & Nicolás Manito. (2017) Benefit of tolvaptan in the management of hyponatraemia in patients with diuretic-refractory congestive heart failure: the SEMI-SEC project. ESC Heart Failure 4:2, pages 130-137.
Crossref
Benlei Li, Dong Fang, Cheng Qian, Hongliang Feng & Yanggan Wang. (2016) The Efficacy and Safety of Tolvaptan in Patients with Hyponatremia: A Meta-Analysis of Randomized Controlled Trials. Clinical Drug Investigation 37:4, pages 327-342.
Crossref
Kevan E. Meadors & Deborah B. Diercks. 2017. Short Stay Management of Acute Heart Failure. Short Stay Management of Acute Heart Failure 223 232 .
Renato De Vecchis, Marco Di Maio, Giuseppina Di Biase & Carmelina Ariano. (2016) Effects of Hyponatremia Normalization on the Short-Term Mortality and Rehospitalizations in Patients with Recent Acute Decompensated Heart Failure: A Retrospective Study. Journal of Clinical Medicine 5:10, pages 92.
Crossref
Jack F. Price, Paul F. Kantor, Robert E. Shaddy, Joseph W. Rossano, Jason F. Goldberg, Joseph Hagan, Timothy J. Humlicek, Antonio G. Cabrera, Aamir Jeewa, Susan W. Denfield, William J. Dreyer & Ayse Akcan-Arikan. (2016) Incidence, Severity, and Association With Adverse Outcome of Hyponatremia in Children Hospitalized With Heart Failure. The American Journal of Cardiology 118:7, pages 1006-1010.
Crossref
E. Alskaf, A. Tridente & A. Al-Mohammad. (2016) Tolvaptan for Heart Failure, Systematic Review and Meta-Analysis of Trials. Journal of Cardiovascular Pharmacology 68:3, pages 196-203.
Crossref
Jacques D. Donzé, Patrick E. Beeler & David W. Bates. (2016) Impact of Hyponatremia Correction on the Risk for 30-Day Readmission and Death in Patients with Congestive Heart Failure. The American Journal of Medicine 129:8, pages 836-842.
Crossref
Bojana Radulović, Ines Potočnjak, Sanda Dokoza Terešak, Matias Trbušić, Nada Vrkić, Davorin Malogorski, Neven Starčević, Milan Milošević, Saša Frank & Vesna Degoricija. (2016) Hypochloraemia as a predictor of developing hyponatraemia and poor outcome in acute heart failure patients. International Journal of Cardiology 212, pages 237-241.
Crossref
Kenji Yoshioka, Yuya Matsue, Nobuyuki Kagiyama, Kazuki Yoshida, Teruyoshi Kume, Hiroyuki Okura, Makoto Suzuki, Akihiko Matsumura, Kiyoshi Yoshida & Yuji Hashimoto. (2016) Recovery from hyponatremia in acute phase is associated with better in-hospital mortality rate in acute heart failure syndrome. Journal of Cardiology 67:5, pages 406-411.
Crossref
Joseph G. Verbalis, Arthur Greenberg, Volker Burst, Jean-Philippe Haymann, Gudmundur Johannsson, Alessandro Peri, Esteban Poch, Joseph A. ChiodoIIIIII & Jiten Dave. (2016) Diagnosing and Treating the Syndrome of Inappropriate Antidiuretic Hormone Secretion. The American Journal of Medicine 129:5, pages 537.e9-537.e23.
Crossref
Dai‐Yin Lu, Hao‐Min Cheng, Yu‐Lun Cheng, Pai‐Feng Hsu, Wei‐Ming Huang, Chao‐Yu Guo, Wen‐Chung Yu, Chen‐Huan Chen & Shih‐Hsien Sung. (2016) Hyponatremia and Worsening Sodium Levels Are Associated With Long‐Term Outcome in Patients Hospitalized for Acute Heart Failure. Journal of the American Heart Association 5:3.
Crossref
Kerri McGreal, Pooja Budhiraja, Nishank Jain & Alan S.L. Yu. (2016) Current Challenges in the Evaluation and Management of Hyponatremia. Kidney Diseases 2:2, pages 56-63.
Crossref
James J. DiNicolantonio, Subhankar Chatterjee & James H. O’Keefe. (2016) Dietary Salt Restriction in Heart Failure: Where Is the Evidence?. Progress in Cardiovascular Diseases 58:4, pages 401-406.
Crossref
Bo Xiong, Yuwen Huang, Jie Tan, Yuanqing Yao, Chunbin Wang, Jun Qian, Shunkang Rong, Shimin Deng, Yin Cao, Yanke Zou & Jing Huang. (2015) The short-term and long-term effects of tolvaptan in patients with heart failure: a meta-analysis of randomized controlled trials. Heart Failure Reviews 20:6, pages 633-642.
Crossref
R. Berardi, M. Caramanti, M. Castagnani, S. Guglielmi, F. Marcucci, A. Savini, F. Morgese, S. Rinaldi, C. Ferrini, M. Tiberi, M. Torniai, F. Rovinelli, I. Fiordoliva, A. Onofri & S. Cascinu. (2015) Hyponatremia is a predictor of hospital length and cost of stay and outcome in cancer patients. Supportive Care in Cancer 23:10, pages 3095-3101.
Crossref
Brian A. Houston, Rohan J. Kalathiya, Daniel A. Kim & Sammy Zakaria. (2015) Volume Overload in Heart Failure. Mayo Clinic Proceedings 90:9, pages 1247-1261.
Crossref
Prateeti Khazanie, Gretchen M. Heizer, Vic Hasselblad, Paul W. Armstrong, Robert M. Califf, Justin Ezekowitz, Kenneth Dickstein, Wayne C. Levy, John J.V. McMurray, Marco Metra, W.H. Wilson Tang, John R. Teerlink, Adriaan A. Voors, Christopher M. O’Connor, Adrian F. Hernandez & Randall Starling. (2015) Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models. American Heart Journal 170:2, pages 290-297.e1.
Crossref
Arthur Greenberg, Joseph G. Verbalis, Alpesh N. Amin, Volker R. Burst, Joseph A. Chiodo III, Jun R. Chiong, Joseph F. Dasta, Keith E. Friend, Paul J. Hauptman, Alessandro Peri & Samuel H. Sigal. (2015) Current treatment practice and outcomes. Report of the hyponatremia registry. Kidney International 88:1, pages 167-177.
Crossref
Antoine Braconnier, Laurence Vrigneaud & Jean-Philippe Bertocchio. (2015) Hyponatrémies : de la physiopathologie aux traitements. Revue de la littérature pour le clinicien. Néphrologie & Thérapeutique 11:4, pages 201-212.
Crossref
Giovanni Corona, Corinna Giuliani, Joseph G. Verbalis, Gianni Forti, Mario Maggi & Alessandro Peri. (2015) Hyponatremia Improvement Is Associated with a Reduced Risk of Mortality: Evidence from a Meta-Analysis. PLOS ONE 10:4, pages e0124105.
Crossref
Vicente E. Torres. (2015) Vasopressin Receptor Antagonists, Heart Failure, and Polycystic Kidney Disease. Annual Review of Medicine 66:1, pages 195-210.
Crossref
Biff F. Palmer. (2015) Vasopressin Receptor Antagonists. Current Hypertension Reports 17:1.
Crossref
Giorgio Graziani, Daniela Pini, Silvia Oldani, David Cucchiari, Manuel Alfredo Podestà & Salvatore Badalamenti. (2013) Renal dysfunction in acute congestive heart failure: a common problem for cardiologists and nephrologists. Heart Failure Reviews 19:6, pages 699-708.
Crossref
Tess E. Lin, Kirkwood F. AdamsJr.Jr. & J. Herbert Patterson. (2014) Potential Roles of Vaptans in Heart Failure. Heart Failure Clinics 10:4, pages 607-620.
Crossref
Joseph D. Walch, T. Prashant Nedungadi & J. Thomas Cunningham. (2014) ANG II receptor subtype 1a gene knockdown in the subfornical organ prevents increased drinking behavior in bile duct-ligated rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 307:6, pages R597-R607.
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Fabio A.B. Schutz, Wanling Xie, Frede Donskov, Monica Sircar, David F. McDermott, Brian I. Rini, Neeraj Agarwal, Sumanta Kumar Pal, Sandy Srinivas, Christian Kollmannsberger, Scott A. North, Lori A. Wood, Ulka Vaishampayan, Min-Han Tan, Mary J. Mackenzie, Jae Lyun Lee, Sun-Young Rha, Takeshi Yuasa, Daniel Y.C. Heng & Toni K. Choueiri. (2014) The Impact of Low Serum Sodium on Treatment Outcome of Targeted Therapy in Metastatic Renal Cell Carcinoma: Results from the International Metastatic Renal Cell Cancer Database Consortium. European Urology 65:4, pages 723-730.
Crossref
Jonathan D. Cicci, Brent N. Reed, Elizabeth B. McNeely, Akinyemi Oni-Orisan, J. Herbert Patterson & Jo E. Rodgers. (2014) Acute Decompensated Heart Failure: Evolving Literature and Implications for Future Practice. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 34:4, pages 373-388.
Crossref
Ankur Kalra, Valmiki Maharaj & Steven R Goldsmith. (2013) Vasopressin Receptor Antagonists: From Pivotal Trials to Current Practice. Current Heart Failure Reports 11:1, pages 10-18.
Crossref
Tien M.H. Ng, Diana X. Cao, Komal A. Patel, Yee May Wong, Megha Prasad, Mimi Lou & Uri Elkayam. (2014) Association of Hyponatremia to Diuretic Response and Incidence of Increased Serum Creatinine Levels in Hospitalized Patients with Acute Decompensated Heart Failure. Cardiology 128:4, pages 333-342.
Crossref
J. Häggström, A. Boswood, M. O'Grady, O. Jöns, S. Smith, S. Swift, M. Borgarelli, B. Gavaghan, J.‐G. Kresken, M. Patteson, B. Åblad, C.M. Bussadori, T. Glaus, A. Kovačević, M. Rapp, R.A. Santilli, A. Tidholm, A. Eriksson, M.C. Belanger, M. Deinert, C.J.L. Little, C. Kvart, A. French, M. Rønn‐Landbo, G. Wess, A. Eggertsdottir, M. Lynne O'Sullivan, M. Schneider, C.W. Lombard, J. Dukes‐McEwan, R. Willis, A. Louvet & R. DiFruscia. (2013) Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Myxomatous Mitral Valve Disease Receiving Pimobendan or Benazepril: The QUEST Study. Journal of Veterinary Internal Medicine 27:6, pages 1441-1451.
Crossref
Joseph G. Verbalis, Steven R. Goldsmith, Arthur Greenberg, Cynthia Korzelius, Robert W. Schrier, Richard H. Sterns & Christopher J. Thompson. (2013) Diagnosis, Evaluation, and Treatment of Hyponatremia: Expert Panel Recommendations. The American Journal of Medicine 126:10, pages S1-S42.
Crossref
Ruediger W. Lehrich, David I. Ortiz-Melo, Mehul B. Patel & Arthur Greenberg. (2013) Role of Vaptans in the Management of Hyponatremia. American Journal of Kidney Diseases 62:2, pages 364-376.
Crossref
Steven R. Goldsmith. (2013) Hyponatremia in Heart Failure: Time for a Trial. Journal of Cardiac Failure 19:6, pages 398-400.
Crossref
Juan A. Crestanello, Gary Phillips, Michael S. Firstenberg, Chittoor Sai-Sudhakar, John Sirak, Robert Higgins & William T. Abraham. (2013) Preoperative hyponatremia predicts outcomes after cardiac surgery. Journal of Surgical Research 181:1, pages 60-66.
Crossref
Alessandro Peri. (2013) The Use of Vaptans in Clinical Endocrinology. The Journal of Clinical Endocrinology & Metabolism 98:4, pages 1321-1332.
Crossref
Joseph D. Walch, Flávia Regina Carreño & J. Thomas Cunningham. (2013) Intracerebroventricular losartan infusion modulates angiotensin II type 1 receptor expression in the subfornical organ and drinking behaviour in bile‐duct‐ligated rats. Experimental Physiology 98:4, pages 922-933.
Crossref
Mohammad Sarraf & Steven R. Goldsmith. 2013. Hyponatremia. Hyponatremia 127 143 .
Maryam Rahman, Nathan Kohler & Azra Bihorac. 2013. Textbook of Neurointensive Care. Textbook of Neurointensive Care 355 378 .
Louise Balling, Caroline Kistorp, Morten Schou, Michael Egstrup, Ida Gustafsson, Jens Peter Goetze, Per Hildebrandt & Finn Gustafsson. (2012) Plasma Copeptin Levels and Prediction of Outcome in Heart Failure Outpatients: Relation to Hyponatremia and Loop Diuretic Doses. Journal of Cardiac Failure 18:5, pages 351-358.
Crossref
Paul J. Hauptman. (2012) Clinical challenge of hyponatremia in heart failure. Journal of Hospital Medicine 7:S4.
Crossref
C. P. Kovesdy. (2012) Significance of hypo- and hypernatremia in chronic kidney disease. Nephrology Dialysis Transplantation 27:3, pages 891-898.
Crossref
Beth WilmotV. Saroja VorugantiYen-Pei C. ChangYi FuZhan ChenHerman A. TaylorJames G. WilsonTeresa Gipson, Vallabh O. Shah, Jason G. Umans, Michael F. FlessnerRobert Hitzemann, Alan R. ShuldinerAnthony G. ComuzzieShannon McWeeneyPhilip G. Zager, Jean W. MacCluerShelley A. ColeDavid M. Cohen. (2012) Heritability of serum sodium concentration: evidence for sex- and ethnic-specific effects. Physiological Genomics 44:3, pages 220-228.
Crossref
Rachel Rockford & Deborah B. Diercks. 2012. Short Stay Management of Acute Heart Failure. Short Stay Management of Acute Heart Failure 199 206 .
J. Herbert Patterson, Kirkwood F. AdamsJrJr, Theresa Human & Denise H. Rhoney. (2017) Case Studies in Hypervolemic Hyponatremia. Hospital Pharmacy 46:12_suppl2, pages 39-44.
Crossref
J. Herbert Patterson. (2017) Hyponatremia's Impact on Patients and Health Systems. Hospital Pharmacy 46:12_suppl2, pages 3-10.
Crossref
Theresa Human. (2017) Therapeutic Options in Managing Hyponatremia: Focus on Arginine Vasopressin Receptor Antagonists. Hospital Pharmacy 46:12_suppl2, pages 20-29.
Crossref
Vinay D. MadanEric NovakMichael W. Rich. (2011) Impact of Change in Serum Sodium Concentration on Mortality in Patients Hospitalized With Heart Failure and Hyponatremia. Circulation: Heart Failure 4:5, pages 637-643.
Crossref
Peter A. Gross, Andrea Wagner & Guy Decaux. (2011) Vaptans are not the mainstay of treatment in hyponatremia: perhaps not yet. Kidney International 80:6, pages 594-600.
Crossref
Gregory Valania, Manmeet Singh & Mara T. Slawsky. (2010) Targeting Hyponatremia and Hemodynamics in Acute Decompensated Heart Failure: Is There a Role for Vasopressin Antagonists?. Current Heart Failure Reports 8:3, pages 198-205.
Crossref
Vincent E. Friedewald, Michael Emmett, Mihai Gheorghiade & William C. Roberts. (2011) The Editor's Roundtable: Pathophysiology and Management of Hyponatremia and the Role of Vasopressin Antagonists. The American Journal of Cardiology 107:9, pages 1357-1364.
Crossref
Gary L. Robertson. (2011) Vaptans for the treatment of hyponatremia. Nature Reviews Endocrinology 7:3, pages 151-161.
Crossref
Philip L. CyrKatherine A. SlawskyNatalia OlchanskiHolly B. KrasaThomas F. GossChristopher ZimmerPaul J. Hauptman. (2011) Effect of serum sodium concentration and tolvaptan treatment on length of hospitalization in patients with heart failure. American Journal of Health-System Pharmacy 68:4, pages 328-333.
Crossref
Paula Martínez-Santos & Isidre Vilacosta. (2011) Cardiorenal Syndrome: An Unsolved Clinical Problem. International Journal of Nephrology 2011, pages 1-6.
Crossref
Yuko Tada, Tomohiro Nakamura, Hiroshi Funayama, Yoshitaka Sugawara, Junya Ako, San-e Ishikawa & Shin-ichi Momomura. (2011) Early Development of Hyponatremia Implicates Short- and Long-Term Outcomes in ST-Elevation Acute Myocardial Infarction. Circulation Journal 75:8, pages 1927-1933.
Crossref
Andrew F. Shorr, Ying P. Tabak, Richard S. Johannes, Vikas Gupta, Mitchell T. Saltzberg & Maria R. Costanzo. (2011) Burden of Sodium Abnormalities in Patients Hospitalized for Heart Failure. Congestive Heart Failure 17:1, pages 1-7.
Crossref
Geoffrey T. Jao & Jun R. Chiong. (2010) Hyponatremia in Acute Decompensated Heart Failure: Mechanisms, Prognosis, and Treatment Options. Clinical Cardiology 33:11, pages 666-671.
Crossref
Punniyakoti T. Veeraveedu, Suresh S. Palaniyandi, Ken’ichi Yamaguchi, Yutaka Komai, Rajarajan A. Thandavarayan, Vijayakumar Sukumaran & Kenichi Watanabe. (2010) Arginine vasopressin receptor antagonists (vaptans): pharmacological tools and potential therapeutic agents. Drug Discovery Today 15:19-20, pages 826-841.
Crossref
Benaya Rozen-Zvi, Dafna Yahav, Mihai Gheorghiade, Asher Korzets, Leonard Leibovici & Uzi Gafter. (2010) Vasopressin Receptor Antagonists for the Treatment of Hyponatremia: Systematic Review and Meta-analysis. American Journal of Kidney Diseases 56:2, pages 325-337.
Crossref
Jalal K. Ghali & S. William Tam. (2010) The Critical Link of Hypervolemia and Hyponatremia in Heart Failure and the Potential Role of Arginine Vasopressin Antagonists. Journal of Cardiac Failure 16:5, pages 419-431.
Crossref
A N Jeppesen, H K Jensen, F Donskov, N Marcussen & H von der Maase. (2010) Hyponatremia as a prognostic and predictive factor in metastatic renal cell carcinoma. British Journal of Cancer 102:5, pages 867-872.
Crossref
Steven R. Goldsmith, Filippo Brandimarte & Mihai Gheorghiade. (2010) Congestion as a Therapeutic Target in Acute Heart Failure Syndromes. Progress in Cardiovascular Diseases 52:5, pages 383-392.
Crossref
Chirag Parikh & Tomas Berl. 2010. Comprehensive Clinical Nephrology. Comprehensive Clinical Nephrology 100 117 .
Maryam Rahman & William A. Friedman. (2009) HYPONATREMIA IN NEUROSURGICAL PATIENTS. Neurosurgery 65:5, pages 925-936.
Crossref
Kanu Chatterjee. (2009) Analytic Review: Hyponatremia in Heart Failure. Journal of Intensive Care Medicine 24:6, pages 347-351.
Crossref
WH Wilson Tang. (2009) Biomarkers of risk stratification in congestive heart failure: North American view. Biomarkers in Medicine 3:5, pages 443-452.
Crossref
Dimitrios Farmakis, Gerasimos Filippatos, John Parissis, Dimitrios Th. Kremastinos & Mihai Gheorghiade. (2008) Hyponatremia in heart failure. Heart Failure Reviews 14:2, pages 59-63.
Crossref
Ashish Upadhyay, Bertrand L. Jaber & Nicolaos E. Madias. (2009) Epidemiology of Hyponatremia. Seminars in Nephrology 29:3, pages 227-238.
Crossref
R. Lemmens-Gruber. (2009) VasopressinantagonistenVasopressin antagonists. Der Kardiologe 3:2, pages 160-163.
Crossref
Eduardo Delgado Parada, Francisco Manuel Suárez García, Juan Carlos Miñana Climent, Alfonso Medina García, Virginia López Gaona, Solange Gutiérrez Vara & Juan José Solano Jaurrieta. (2009) Variables asociadas a deterioro funcional al alta y a los 3 meses en ancianos hospitalizados por insuficiencia cardíaca. Revista Española de Geriatría y Gerontología 44:2, pages 66-72.
Crossref
Dan Rusinaru, Otilia Buiciuc, Laurent Leborgne, Michel Slama, Ziad Massy & Christophe Tribouilloy. (2009) Relation of Serum Sodium Level to Long-Term Outcome After a First Hospitalization for Heart Failure With Preserved Ejection Fraction. The American Journal of Cardiology 103:3, pages 405-410.
Crossref
Gerasimos Filippatos & John T. Parissis. (2008) Vasopressin Antagonists for the Treatment of Acute Decompensated Heart Failure: When, for Whom, for How Long, and on What Standard Therapy?. Journal of Cardiac Failure 14:8, pages 648-650.
Crossref
Dimitrios Farmakis, Gerasimos Filippatos, Dimitrios T. Kremastinos & Mihai Gheorghiade. (2008) Vasopressin and vasopressin antagonists in heart failure and hyponatremia. Current Heart Failure Reports 5:2, pages 91-96.
Crossref
R. Lemmens-Gruber & M. Kamyar. (2008) Pharmakologie und klinische Bedeutung von VasopressinantagonistenPharmacology and clinical relevance of vasopressin antagonists. Der Internist 49:5, pages 628-634.
Crossref
. 2008. Herzinsuffizienz. Herzinsuffizienz 187 196 .
Filippo Brandimarte, Francesco Fedele, Leonardo De Luca, Gregg C. Fonarow & Mihai Gheorghiade. (2007) Hyponatremia in acute heart failure syndromes: A potential therapeutic target. Current Heart Failure Reports 4:4, pages 207-213.
Crossref

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