Citations (49)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (6)
Adam Slavick, Victoria Furer, Ari Polachek, Reut Tzemach, Ori Elkayam & Smadar Gertel. (2023) Circulating and Synovial Monocytes in Arthritis and Ex-Vivo Model to Evaluate Therapeutic Modulation of Synovial Monocytes. Immunological Investigations 52:7, pages 832-855.
Read now
Read now
Hyun Jeong Kim, Nga Thi Trinh, Yunjeong Choi, Woorim Kim, Kyung Hyun Min, Sang Oh Kang, Joo Hee Kim, Hyoun-Ah Kim, Ju-Yang Jung, In Ah Choi & Kyung Eun Lee. (2020) ADAM17 Genetic Variants and the Response of TNF-α Inhibitor in Rheumatoid Arthritis Patients. Pharmacogenomics and Personalized Medicine 13, pages 81-88.
Read now
Read now
Robin E. Walsh, Megan Lannan, Yi Wen, Xiaoli Wang, Christopher A. Moreland, Jill Willency, Michael D. Knierman, Laura Spindler, Ling Liu, Wei Zeng, Guilherme V. Rocha, Victor Obungu, Jirong Lu, Arunan Kaliyaperumal, Andrea Ferrante, Robert Siegel & Laurent P. Malherbe. (2020) Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms. mAbs 12:1.
Read now
Read now
Nicoletta Bivi, Terry Moore, George Rodgers, Heather Denning, Travis Shockley, Craig A. Swearingen, Valentina Gelfanova, Boris Calderon, Daniel A. Peterson, Michael E. Hodsdon, Robert W. Siegel, Richard E. Higgs & Robert J. Konrad. (2019) Investigation of pre-existing reactivity to biotherapeutics can uncover potential immunogenic epitopes and predict immunogenicity risk. mAbs 11:5, pages 861-869.
Read now
Read now
Adam W. Clarke, Lynn Poulton, Doris Shim, David Mabon, Danyal Butt, Matthew Pollard, Vanya Pande, Jean Husten, Jacquelyn Lyons, Chen Tian & Anthony G. Doyle. (2018) An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease. mAbs 10:4, pages 664-677.
Read now
Read now
Takayuki Hoshiyama, Yu Matsueda, Toshihiro Tono, Yoshiyuki Arinuma, Tatsuo Nagai & Shunsei Hirohata. (2018) Differential influences of Fc gamma receptor blocking on the effects of certolizumab pegol and infliximab on human monocytes. Modern Rheumatology 28:3, pages 506-512.
Read now
Read now
Articles from other publishers (43)
Maria Lteif, Marc Pallardy & Isabelle Turbica. (2023) Antibodies internalization mechanisms by dendritic cells and their role in therapeutic antibody immunogenicity. European Journal of Immunology.
Crossref
Crossref
Justin M. Howe, Siteng Fang, Kelsey A. Watts, Fanny Xu, Samantha R. Benjamin & L. Nathan Tumey. (2023) ValCitGlyPro-dexamethasone antibody conjugates selectively suppress the activation of human monocytes. RSC Medicinal Chemistry 14:11, pages 2348-2357.
Crossref
Crossref
Janet M. Sasso, Rumiana Tenchov, Robert Bird, Kavita A. Iyer, Krittika Ralhan, Yacidzohara Rodriguez & Qiongqiong Angela Zhou. (2023) The Evolving Landscape of Antibody–Drug Conjugates: In Depth Analysis of Recent Research Progress. Bioconjugate Chemistry 34:11, pages 1951-2000.
Crossref
Crossref
Ronilda D’Cunha, Hartmut Kupper, Dilek Arikan, Weihan Zhao, David Carter, Jonas Blaes, Melanie Ruzek & Yinuo Pang. (2023) A first‐in‐human study of the novel immunology antibody drug conjugate, ABBV‐3373, in healthy participants. British Journal of Clinical Pharmacology.
Crossref
Crossref
Jochem Gokemeijer, Yi Wen, Vibha Jawa, Shibani Mitra-Kaushik, Shan Chung, Alan Goggins, Seema Kumar, Kasper Lamberth, Karen Liao, Jennie Lill, Qui Phung, Robin Walsh, Brian J. Roberts, Michael Swanson, Inderpal Singh, Sophie Tourdot, Mark A. Kroenke, Bonita Rup, Theresa J. Goletz, Swati Gupta, Laurent Malherbe & Sofie Pattijn. (2023) Survey Outcome on Immunogenicity Risk Assessment Tools for Biotherapeutics: an Insight into Consensus on Methods, Application, and Utility in Drug Development. The AAPS Journal 25:4.
Crossref
Crossref
Hsuan Ping Chang, Yuen Kiu Cheung & Dhaval K. Shah. 2023. Overcoming Obstacles in Drug Discovery and Development. Overcoming Obstacles in Drug Discovery and Development
75
106
.
Marwan Bouras, Karim Asehnoune & Antoine Roquilly. (2022) Immune modulation after traumatic brain injury. Frontiers in Medicine 9.
Crossref
Crossref
Theodora Kalpachidou, Lydia Riehl, Clemens L. Schöpf, Buket Ucar & Michaela Kress. (2022) Proinflammatory cytokines and their receptors as druggable targets to alleviate pathological pain. Pain 163:S1, pages S79-S98.
Crossref
Crossref
J. Monty Watkins & Jeffry D. Watkins. (2022) An Engineered Monovalent Anti–TNF-α Antibody with pH-Sensitive Binding Abrogates Immunogenicity in Mice following a Single Intravenous Dose. The Journal of Immunology 209:4, pages 829-839.
Crossref
Crossref
Yanchen Zhou, Hweixian L Penny, Mark A Kroenke, Bianca Bautista, Kelly Hainline, Lynette S Chea, Jane Parnes & Daniel T Mytych. (2022) Immunogenicity assessment of bispecific antibody-based immunotherapy in oncology. Journal for ImmunoTherapy of Cancer 10:4, pages e004225.
Crossref
Crossref
Peter S. Dragovich. (2022) Antibody–Drug Conjugates for Immunology. Journal of Medicinal Chemistry 65:6, pages 4496-4499.
Crossref
Crossref
Adrian D. Hobson, Michael J. McPherson, Wendy Waegell, Christian A. Goess, Robert H. Stoffel, Xiang Li, Jian Zhou, Zhongyuan Wang, Yajie Yu, Axel HernandezJr.Jr., Shaughn H. Bryant, Suzanne L. Mathieu, Agnieszka K. Bischoff, Julia Fitzgibbons, Martyna Pawlikowska, Sujiet Puthenveetil, Ling C. Santora, Lu Wang, Lu Wang, Christopher C. Marvin, Martin E. Hayes, Anurupa Shrestha, Kathy A. Sarris & Biqin Li. (2022) Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody–Drug Conjugate Payloads. Journal of Medicinal Chemistry 65:6, pages 4500-4533.
Crossref
Crossref
Markus Ries, Brice Moulari, Maryam A. Shetab Boushehri, Mohamed Ehab Ali, Daniel Molnar, Arnaud Béduneau, Yann Pellequer & Alf Lamprecht. (2022) Adalimumab Decorated Nanoparticles Enhance Antibody Stability and Therapeutic Outcome in Epithelial Colitis Targeting. Pharmaceutics 14:2, pages 352.
Crossref
Crossref
Susan D. Ghiassian, Johanna B. Withers, Marc Santolini, Alif Saleh & Viatcheslav R. Akmaev. (2022) RETRACTED: Network-based response module comprised of gene expression biomarkers predicts response to infliximab at treatment initiation in ulcerative colitis. Translational Research 239, pages 35-43.
Crossref
Crossref
David Ternant, Marc Pfister, Olivier Le Tilly, Denis Mulleman, Laurence Picon, Stéphanie Willot, Christophe Passot, Theodora Bejan-Angoulvant, Thierry Lecomte, Gilles Paintaud & Gilbert Koch. (2021) Infliximab Treatment Does Not Lead to Full TNF-α Inhibition: A Target-Mediated Drug Disposition Model. Clinical Pharmacokinetics 61:1, pages 143-154.
Crossref
Crossref
Mark A. Kroenke, Troy E. Barger, Jenny Hu, Mieke Jill Miller, Kevin Kalenian, Lidong He, Hailing Hsu, Yessenia Bartley, Vincent Fung-Sing Chow, Marcia Cristina Teixeira dos Santos, Barbara A. Sullivan, Laurence E. Cheng, Jane R. Parnes, Rupa Padaki, Scott Kuhns & Daniel T. Mytych. (2021) Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target. Frontiers in Immunology 12.
Crossref
Crossref
David Ternant, Olivier Le Tilly, Laurence Picon, Driffa Moussata, Christophe Passot, Theodora Bejan-Angoulvant, Céline Desvignes, Denis Mulleman, Philippe Goupille & Gilles Paintaud. (2021) Infliximab Efficacy May Be Linked to Full TNF-α Blockade in Peripheral Compartment—A Double Central-Peripheral Target-Mediated Drug Disposition (TMDD) Model. Pharmaceutics 13:11, pages 1821.
Crossref
Crossref
Mark A. Kroenke, Mark N. Milton, Seema Kumar, Eris Bame & Joleen T. White. (2021) Immunogenicity Risk Assessment for Multi-specific Therapeutics. The AAPS Journal 23:6.
Crossref
Crossref
Yi Wen, Xiaoli Wang, Suntara Cahya, Paul Anderson, Candyd Velasquez, Carina Torres, Andrea Ferrante & Arunan Kaliyaperumal. (2021) Comparability study of monocyte derived dendritic cells, primary monocytes, and THP1 cells for innate immune responses. Journal of Immunological Methods 498, pages 113147.
Crossref
Crossref
Marcin Wawrzyniak, Yasser Morsy, Radoslav Mladenov, Giulia Tontodonati, Yagmur Turgay, Stefan Herwig, Jonathan Back, Manuela Mally, Amirreza Faridmoayer & Michael Scharl. (2021) Fucosylation and Sialylation of Fc-Fragment of anti-Tumour Necrosis Factor Alpha Antibodies do not Influence Their Immunogenicity in Monocyte-Derived Dendritic Cells. Journal of Crohn's and Colitis 15:9, pages 1596-1601.
Crossref
Crossref
Ai Minamidate, Michio Onizawa, Chikako Saito, Rie Hikichi, Tomoaki Mochimaru, Mai Murakami, Chiharu Sakuma, Takehito Asakawa, Yuichi Hiraoka, Shigeru Oshima, Takashi Nagaishi, Kiichiro Tsuchiya, Hiromasa Ohira, Ryuichi Okamoto & Mamoru Watanabe. (2021) A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production. Biochemistry and Biophysics Reports 27, pages 101065.
Crossref
Crossref
Mimmi L. E. Lundahl, Silvia Fogli, Paula E. Colavita & Eoin M. Scanlan. (2021) Aggregation of protein therapeutics enhances their immunogenicity: causes and mitigation strategies. RSC Chemical Biology 2:4, pages 1004-1020.
Crossref
Crossref
Sivan Cohen & Shan Chung. (2021)
In vitro
immunogenicity prediction: bridging between innate and adaptive immunity
. Bioanalysis 13:13, pages 1071-1081.
Crossref
Crossref
Yiru Zhou, Ruihua Fan, Benson O. A. Botchway, Yong Zhang & Xuehong Liu. (2021) Infliximab Can Improve Traumatic Brain Injury by Suppressing the Tumor Necrosis Factor Alpha Pathway. Molecular Neurobiology 58:6, pages 2803-2811.
Crossref
Crossref
Donald J. AbrahamL. Nathan Tumey. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery
1
39
.
Katy Diallo, Numa Simons, Souraya Sayegh, Michel Baron, Yannick Degboé, Jean-Frédéric Boyer, Andrey Kruglov, Sergei Nedospasov, Julien Novarino, Meryem Aloulou, Nicolas Fazilleau, Arnaud Constantin, Alain Cantagrel, Jean-Luc Davignon & Benjamin Rauwel. (2021) Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation. iScience 24:4, pages 102331.
Crossref
Crossref
Xiaohan Liu, Siwen Li, Yuan Meng, Yu Fan, Jie Liu, Ce Shi, Feilong Ren, Lin Wu, Jinyan Wang & Hongchen Sun. (2021) Osteoclast differentiation and formation induced by titanium implantation through complement C3a. Materials Science and Engineering: C 122, pages 111932.
Crossref
Crossref
Keith J. Arlotta, Boi Hoa San, Hong-Hua Mu, S. Michael Yu & Shawn C. Owen. (2020) Localization of Therapeutic Fab-CHP Conjugates to Sites of Denatured Collagen for the Treatment of Rheumatoid Arthritis. Bioconjugate Chemistry 31:8, pages 1960-1970.
Crossref
Crossref
Yi Wen, Suntara Cahya, Wei Zeng, Joanne Lin, Xiaoli Wang, Ling Liu, Laurent Malherbe, Robert Siegel, Andrea Ferrante & Arunan Kaliyaperumal. (2020) Development of a FRET-Based Assay for Analysis of mAbs Internalization and Processing by Dendritic Cells in Preclinical Immunogenicity Risk Assessment. The AAPS Journal 22:3.
Crossref
Crossref
Tian-Yu Han, Bin Ma, Bing Hu, Liang-Bi Xiang & Xin-Wei Liu. (2020) Effects of Rapamycin Combined with Cisplatin on Tumor Necrosis Factor TNF-α in MG-63 Cells. Cell Transplantation 29, pages 096368972092615.
Crossref
Crossref
W. Blaine Stine, Dana I. Filoti & Tariq Ghayur. 2020. Development of Biopharmaceutical Drug-Device Products. Development of Biopharmaceutical Drug-Device Products
91
115
.
Michael J. McPherson & Adrian D. Hobson. 2020. Antibody-Drug Conjugates. Antibody-Drug Conjugates
23
36
.
Seung Taek Hong, Byumseok Koh, Seong Ji Choi, Eunyoung Yoon, Min Cheol Pyo, Ji-Woo Choi, Mun Seok Kim, Eun Jeong Lee, Kyu Cheol Paik, Man So Han, Hoon Jai Chun, Jung-Nyoung Heo, Eun Sun Kim & Bong Rae Cho. (2019) Two-Photon Probe for TNF-α. Assessment of the Transmembrane TNF-α Level in Human Colon Tissue by Two-Photon Microscopy. Analytical Chemistry 91:24, pages 15769-15776.
Crossref
Crossref
Feng Dong & Tariq Ghayur. (2019) Recent advancements in DVD-Ig based therapeutic development. Drug Discovery Today: Technologies 34, pages 1-7.
Crossref
Crossref
Tawfik Khoury & Yaron Ilan. (2019) Introducing Patterns of Variability for Overcoming Compensatory Adaptation of the Immune System to Immunomodulatory Agents: A Novel Method for Improving Clinical Response to Anti-TNF Therapies. Frontiers in Immunology 10.
Crossref
Crossref
Weigang Shu, Zhi Pang, Chunjin Xu, Jian Lin, Gengfeng Li, Wei Wu, Suofeng Sun, Junxiang Li, Xiuling Li & Zhanju Liu. (2019)
Anti-TNF-
α
Monoclonal Antibody Therapy Improves Anemia through Downregulating Hepatocyte Hepcidin Expression in Inflammatory Bowel Disease
. Mediators of Inflammation 2019, pages 1-13.
Crossref
Crossref
Natalia Kovalova, Michael D Knierman, Patricia L Brown-Augsburger, Victor J Wroblewski & Lukasz K Chlewicki. (2019) Correlation between antidrug antibodies, pre-existing antidrug reactivity, and immunogenetics (MHC class II alleles) in cynomolgus macaque. Immunogenetics 71:10, pages 605-615.
Crossref
Crossref
Won-Ha Lee, Donggun Seo, Su-Geun Lim & Kyoungho Suk. (2019) Reverse Signaling of Tumor Necrosis Factor Superfamily Proteins in Macrophages and Microglia: Superfamily Portrait in the Neuroimmune Interface. Frontiers in Immunology 10.
Crossref
Crossref
Christian Klein, Wolfgang Schaefer, Joerg T. Regula, Charles Dumontet, Ulrich Brinkmann, Marina Bacac & Pablo Umaña. (2019) Engineering therapeutic bispecific antibodies using CrossMab technology. Methods 154, pages 21-31.
Crossref
Crossref
Sophie Steeland, Claude Libert & Roosmarijn E. Vandenbroucke. (2018) A New Venue of TNF Targeting. International Journal of Molecular Sciences 19:5, pages 1442.
Crossref
Crossref
Shan Yu, Andrew Lim & Matthew S. Tremblay. 2018. Innovations for Next-Generation Antibody-Drug Conjugates. Innovations for Next-Generation Antibody-Drug Conjugates
321
347
.
Yang Qu, Gang Zhao & Hui Li. (2017) Forward and Reverse Signaling Mediated by Transmembrane Tumor Necrosis Factor-Alpha and TNF Receptor 2: Potential Roles in an Immunosuppressive Tumor Microenvironment. Frontiers in Immunology 8.
Crossref
Crossref
Joachim R. Kalden & Hendrik Schulze-Koops. (2017) Immunogenicity and loss of response to TNF inhibitors: implications for rheumatoid arthritis treatment. Nature Reviews Rheumatology 13:12, pages 707-718.
Crossref
Crossref