Advanced search
Publication Cover
mAbs Volume 12, 2020 - Issue 1
Submit an article Journal homepage
3,437
Views
2
CrossRef citations to date
0
Altmetric
Report

Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action

Mark Austina Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UK;b Antibody Discovery & Protein Engineering, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UKCorrespondence[email protected]
View further author information
,
Daniel Burschowskyc Leicester Institute of Structural and Chemical Biology and the Department of Molecular and Cell Biology, University of Leicester, Leicester, UKView further author information
,
Denice T.Y. Chana Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Lesley Jenkinsona Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Stuart Haynesa Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Agata Diamandakisa Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Chitra Seewooruthunc Leicester Institute of Structural and Chemical Biology and the Department of Molecular and Cell Biology, University of Leicester, Leicester, UKView further author information
,
Alexandra Addymana Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Sebastian Fiedlera Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Stephanie Rymana Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Jessica Whitehousea Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Louise H. Slatera Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Andreas V. Hadjinicolaoud MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UKView further author information
,
Uzi Gileadid MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UKView further author information
,
Ellen Gowansa Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Yoko Shibataa Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Michelle Barnarda Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Teresa Kaserere Cancer Research UK, Cancer Therapeutics Unit, The Institute of Cancer Research, London, UKView further author information
,
Pooja Sharmaa Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Nadia M. Luheshif Early Oncology Discovery, Oncology R&D, AstraZeneca, Cambridge, UKView further author information
,
Robert W. Wilkinsonf Early Oncology Discovery, Oncology R&D, AstraZeneca, Cambridge, UKView further author information
,
Tristan J. Vaughanb Antibody Discovery & Protein Engineering, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UKView further author information
,
Sarah V. Holta Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UKView further author information
,
Vincenzo Cerundolod MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UKView further author information
,
Mark D. Carrc Leicester Institute of Structural and Chemical Biology and the Department of Molecular and Cell Biology, University of Leicester, Leicester, UKCorrespondence[email protected]
View further author information
&
Maria A. T. Grovesa Cancer Research UK AstraZeneca Antibody Alliance Laboratory, Cambridge, UK;b Antibody Discovery & Protein Engineering, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UKCorrespondence[email protected]
View further author information
 show all
Article: 1801230 | Received 04 Mar 2020, Accepted 20 Jul 2020, Published online: 03 Sep 2020

Citations (2)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Articles from other publishers (2)

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.