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mAbs Volume 13, 2021 - Issue 1
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Identification of critical chemical modifications and paratope mapping by size exclusion chromatography of stressed antibody-target complexes

Pavel V. Bondarenkoa Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USACorrespondence[email protected]
,
Andrew C. Nicholsa Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USA
,
Gang Xiaoa Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USA
,
Rachel Liuqing Shia Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USA
,
Pik Kay Chana Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USA
,
Thomas M Dillona Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USA
,
Fernando Garcesb Department of Therapeutics Discovery, Amgen Research, Amgen Inc, Thousand Oaks, CA, USA
,
David J. Semina Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USA
&
Margaret S. Riccia Attribute Sciences, Process Development, Amgen Inc, Thousand Oaks, CA, USA
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Article: 1887629 | Received 12 Nov 2020, Accepted 04 Feb 2021, Published online: 21 Feb 2021

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Zhengqi Zhang, Yuetian Yan, Shunhai Wang & Ning Li. (2022) A competitive binding-mass spectrometry strategy for high-throughput evaluation of potential critical quality attributes of therapeutic monoclonal antibodies. mAbs 14:1.
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Rachel Liuqing Shi, Gang Xiao, Thomas M. Dillon, Arnold McAuley, Margaret S. Ricci & Pavel V. Bondarenko. (2021) Identification of critical chemical modifications by size exclusion chromatography of stressed antibody-target complexes with competitive binding. mAbs 13:1.
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Articles from other publishers (2)

Daniel W. Woodall, Christy A. Thomson, Thomas M. Dillon, Arnold McAuley, Lydia B. Green, Ian N. Foltz & Pavel V. Bondarenko. (2023) Native SEC and Reversed-Phase LC–MS Reveal Impact of Fab Glycosylation of Anti-SARS-COV-2 Antibodies on Binding to the Receptor Binding Domain. Analytical Chemistry 95:42, pages 15477-15485.
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Prashant N. Jethva & Michael L. Gross. (2023) Hydrogen deuterium exchange and other mass spectrometry- based approaches for epitope mapping. Frontiers in Analytical Science 3.
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