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Research Paper

Gut microbial bile acid metabolite skews macrophage polarization and contributes to high-fat diet-induced colonic inflammation

Lingyu Wanga Department of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China;b Department of Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, School of Medicine, Shanghai Jiaotong University, Shanghai, China;c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, ChinaView further author information
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Zizhen Gonga Department of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China;b Department of Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, School of Medicine, Shanghai Jiaotong University, Shanghai, China;c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, ChinaView further author information
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Xiuyuan Zhangd State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences(Beijing), Beijing Institute of Lifeomics, Beijing, ChinaView further author information
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Fangxinxing Zhua Department of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China;b Department of Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, School of Medicine, Shanghai Jiaotong University, Shanghai, China;c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, ChinaView further author information
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Yuchen Liud State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences(Beijing), Beijing Institute of Lifeomics, Beijing, ChinaView further author information
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Chaozhi Jind State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences(Beijing), Beijing Institute of Lifeomics, Beijing, ChinaView further author information
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Xixi Dua Department of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China;b Department of Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, School of Medicine, Shanghai Jiaotong University, Shanghai, China;c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, ChinaView further author information
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Congfeng Xue Department of Cardiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China;f Department of Immunology, Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaORCID Iconhttps://orcid.org/0000-0002-8009-4865View further author information
ORCID Icon,
Yingwei Chenb Department of Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, School of Medicine, Shanghai Jiaotong University, Shanghai, China;c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, ChinaView further author information
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Wei Caia Department of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China;b Department of Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, School of Medicine, Shanghai Jiaotong University, Shanghai, China;c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, ChinaCorrespondence[email protected]
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Chunyan Tiand State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences(Beijing), Beijing Institute of Lifeomics, Beijing, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1589-293XView further author information
ORCID Icon &
Jin Wua Department of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China;b Department of Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, School of Medicine, Shanghai Jiaotong University, Shanghai, China;c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, ChinaCorrespondence[email protected]
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Article: 1819155 | Received 29 Nov 2019, Accepted 21 Aug 2020, Published online: 02 Oct 2020

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