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Virulence Volume 12, 2021 - Issue 1
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Research paper

M. tuberculosis CRISPR/Cas proteins are secreted virulence factors that trigger cellular immune responses

Jianjian Jiaoa Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;b University of Chinese Academy of Sciences, Beijing, China
,
Nan Zhenga Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;b University of Chinese Academy of Sciences, Beijing, China
,
Wenjing Weia Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;b University of Chinese Academy of Sciences, Beijing, China
,
Joy Fleminga Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
,
Xingyun Wanga Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
,
Zihui Lic Beijing Chest Hospital, Capital Medical University; Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing, China
,
Lili Zhanga Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
,
Yi Liuc Beijing Chest Hospital, Capital Medical University; Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing, China
,
Zongde Zhangc Beijing Chest Hospital, Capital Medical University; Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing, China
,
Adong Shend Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, Beijing, China
,
Li Chuanyouc Beijing Chest Hospital, Capital Medical University; Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing, ChinaCorrespondence[email protected] [email protected]
,
Lijun Bia Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, ChinaCorrespondence[email protected]
&
Hongtai Zhanga Key Laboratory of RNA Biology and State Key Laboratory of Biomacromolecules, Cas Center of Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9308-5872
ORCID Icon show all
Pages 3032-3044 | Received 10 Mar 2021, Accepted 10 Nov 2021, Published online: 09 Dec 2021

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Kathryn C. Rahlwes, Beatriz R.S. Dias, Priscila C. Campos, Samuel Alvarez-Arguedas & Michael U. Shiloh. (2023) Pathogenicity and virulence of Mycobacterium tuberculosis. Virulence 14:1.
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Articles from other publishers (4)

Rima Zein-Eddine, Guislaine Refrégier, Jorge Cervantes & Noemí Kaoru Yokobori. (2023) The future of CRISPR in Mycobacterium tuberculosis infection. Journal of Biomedical Science 30:1.
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Qun Wu, Luqing Cui, Yingying Liu, Rongpeng Li, Menghong Dai, Zhenwei Xia & Min Wu. (2022) CRISPR-Cas systems target endogenous genes to impact bacterial physiology and alter mammalian immune responses. Molecular Biomedicine 3:1.
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Rong Yu & Cai Zhang. (2022) miR-124-Antagonist-Loaded Liposomal Nanoparticles Negatively Regulate the Toll-Like Receptor (TLR)-Signaling Pathway in Alveolar Epithelial Cells in Pulmonary Tuberculosis. Journal of Biomaterials and Tissue Engineering 12:12, pages 2343-2351.
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Simeng Hou, Haotian Wu, Si Chen, Xubo Li, Zhenxing Zhang, Yiwen Cheng, Yuanyuan Chen, Meirong He, Qi An, Churiga Man, Li Du, Qiaoling Chen & Fengyang Wang. (2022) Bovine skin fibroblasts mediated immune responses to defend against bovine Acinetobacter baumannii infection. Microbial Pathogenesis 173, pages 105806.
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