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OncoImmunology Volume 8, 2019 - Issue 11
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Brief Report

Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma

Edda BlümelLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0002-3270-9466View further author information
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Andreas Willerslev-OlsenLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0001-9687-7269View further author information
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Maria GluudLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0001-8877-3486View further author information
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Lise M. LindahlDepartment of Dermatology, Aarhus University Hospital, Aarhus, DenmarkORCID Iconhttps://orcid.org/0000-0003-3768-4146View further author information
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Simon FredholmLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0002-8870-949XView further author information
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Claudia NastasiLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0003-4438-0554View further author information
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Thorbjørn KrejsgaardLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0001-6350-1150View further author information
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Bas G. J. SurewaardDepartment of Physiology and Pharmacology, Snyder Institute for Chronic Diseases, University of Calgary, Calgary, CanadaORCID Iconhttps://orcid.org/0000-0001-6367-3235View further author information
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Sergei B. KoralovDepartment of Pathology, New York University School of Medicine, New York, NY, USAORCID Iconhttps://orcid.org/0000-0002-4843-3791View further author information
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Tengpeng HuLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0001-8049-2743View further author information
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Jenny L. PerssonClinical Research Center, Lund University, Lund, Sweden;Department of Molecular Biology, Umeå University, Umeå, SwedenORCID Iconhttps://orcid.org/0000-0001-7682-7678View further author information
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Charlotte Menné BonefeldLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0002-0523-6229View further author information
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Carsten GeislerLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0002-8472-0771View further author information
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Lars IversenDepartment of Dermatology, Aarhus University Hospital, Aarhus, DenmarkView further author information
,
Jürgen C. BeckerTranslational Skin Cancer Research, German Cancer Consortium (DKTK), University Hospital Essen and Deutsches Krebsforschungszentrum (DKFZ), Essen, GermanyORCID Iconhttps://orcid.org/0000-0001-9183-653XView further author information
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Mads Hald AndersenLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark;Center for Cancer Immune Therapy (CCIT), Department of Hematology and Oncology, Copenhagen University Hospital, Herlev Hospital, Herlev, DenmarkORCID Iconhttps://orcid.org/0000-0002-2914-9605View further author information
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Anders WoetmannLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkORCID Iconhttps://orcid.org/0000-0002-3008-735XView further author information
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Terkild Brink BuusLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkCorrespondence[email protected] [email protected]
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Niels ØdumLEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DenmarkCorrespondence[email protected] [email protected]
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Article: e1641387 | Received 26 Apr 2019, Accepted 02 Jul 2019, Published online: 17 Jul 2019

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Pamela B. Allen, Subir Goyal, Jeffrey Switchenko, Erica Tarabadkar, Stephanie Pouch, Priya Parikh, Alex Palmer, Dylan Martini, Esther Kim & Mary Jo Lechowicz. (2023) Mitigation strategies among cutaneous T-cell lymphoma patients with positive Staphylococcus aureus skin and soft tissue cultures have unclear impacts on the risk of subsequent bacteremia. Leukemia & Lymphoma 64:3, pages 597-604.
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Pamela B. Allen, Jeffrey Switchenko, Amy Ayers, Esther Kim & Mary Jo Lechowicz. (2020) Risk of bacteremia in patients with cutaneous T-cell lymphoma (CTCL) . Leukemia & Lymphoma 61:11, pages 2652-2658.
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Edda Blümel, Shamaila Munir Ahmad, Claudia Nastasi, Andreas Willerslev-Olsen, Maria Gluud, Simon Fredholm, Tengpeng Hu, Bas G. J. Surewaard, Lise M. Lindahl, Hanne Fogh, Sergei B. Koralov, Lise Mette Rahbek Gjerdrum, Rachael A. Clark, Lars Iversen, Thorbjørn Krejsgaard, Charlotte Menné Bonefeld, Carsten Geisler, Jürgen C. Becker, Anders Woetmann, Mads Hald Andersen, Terkild Brink Buus & Niels Ødum. (2020) Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma. OncoImmunology 9:1.
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Emil M.H. Pallesen, Maria Gluud, Chella Krishna Vadivel, Terkild B. Buus, Bob de Rooij, Ziao Zeng, Sana Ahmad, Andreas Willerslev-Olsen, Christian Röhrig, Maria R. Kamstrup, Lene Bay, Lise Lindahl, Thorbjørn Krejsgaard, Carsten Geisler, Charlotte M. Bonefeld, Lars Iversen, Anders Woetmann, Sergei B. Koralov, Thomas Bjarnsholt, Johan Frieling, Mathias Schmelcher & Niels Ødum. (2023) Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma. Journal of Investigative Dermatology 143:9, pages 1757-1768.e3.
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Xiangjun Liu, Jingru Sun, Yumei Gao, Fengjie Liu, Haihao Pan, Ping Tu & Yang Wang. (2023) Characteristics of Staphylococcus aureus Colonization in Cutaneous T-Cell Lymphoma. Journal of Investigative Dermatology.
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Daniel E. Luna & Michi M. Shinohara. (2023) New Molecular and Biological Markers in Cutaneous T Cell Lymphoma: Therapeutic Implications. Current Hematologic Malignancy Reports 18:3, pages 83-88.
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Madeline J. Hooper, Gail L. Enriquez, Francesca L. Veon, Tessa M. LeWitt, Dagmar Sweeney, Stefan J. Green, Patrick C. Seed, Jaehyuk Choi, Joan Guitart, Michael B. Burns & Xiaolong A. Zhou. (2022) Narrowband ultraviolet B response in cutaneous T-cell lymphoma is characterized by increased bacterial diversity and reduced Staphylococcus aureus and Staphylococcus lugdunensis. Frontiers in Immunology 13.
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M.J. Hooper, T.M. LeWitt, Y. Pang, F.L. Veon, G.E. Chlipala, L. Feferman, S.J. Green, D. Sweeney, K.T. Bagnowski, M.B. Burns, P.C. Seed, J. Choi, J. Guitart & X.A. Zhou. (2022) Gut dysbiosis in cutaneous T‐cell lymphoma is characterized by shifts in relative abundances of specific bacterial taxa and decreased diversity in more advanced disease. Journal of the European Academy of Dermatology and Venereology 36:9, pages 1552-1563.
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Magdalena Łyko & Alina Jankowska-Konsur. (2022) The Skin Microbiome in Cutaneous T-Cell Lymphomas (CTCL)—A Narrative Review. Pathogens 11:8, pages 935.
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Marion Jost & Ulrike Wehkamp. (2022) The Skin Microbiome and Influencing Elements in Cutaneous T-Cell Lymphomas. Cancers 14:5, pages 1324.
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Carina A. Dehner, William E. Ruff, Teri Greiling, Márcia S. Pereira, Sylvio Redanz, Jennifer McNiff, Michael Girardi & Martin A. Kriegel. (2022) Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions. JID Innovations 2:2, pages 100084.
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Kazuyasu Fujii. (2021) Pathogenesis of cutaneous T cell lymphoma: Involvement of Staphylococcus aureus . The Journal of Dermatology 49:2, pages 202-209.
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Philipp Licht & Volker Mailänder. (2022) Transcriptional Heterogeneity and the Microbiome of Cutaneous T-Cell Lymphoma. Cells 11:3, pages 328.
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Alberto Herrera, Anthony Cheng, Eleni P. Mimitou, Angelina Seffens, Dean GeorgeMichal Bar-NatanAdriana HeguyKelly V. Ruggles, Jose U. Scher, Kenneth Hymes, Jo-Ann LatkowskiNiels Ødum, Marshall E. KadinZhengqing Ouyang, Larisa J. Geskin, Peter Smibert, Terkild B. Buus & Sergei B. Koralov. (2021) Multimodal single-cell analysis of cutaneous T-cell lymphoma reveals distinct subclonal tissue-dependent signatures. Blood 138:16, pages 1456-1464.
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Constanze Jonak, Julia Tittes, Patrick Manfred Brunner & Emmanuella Guenova. (2021) Mycosis fungoides und Sézary‐Syndrom. JDDG: Journal der Deutschen Dermatologischen Gesellschaft 19:9, pages 1307-1335.
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Constanze Jonak, Julia Tittes, Patrick Manfred Brunner & Emmanuella Guenova. (2021) Mycosis fungoides and Sézary syndrome. JDDG: Journal der Deutschen Dermatologischen Gesellschaft 19:9, pages 1307-1334.
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Reinhard Dummer, Maarten H. Vermeer, Julia J. Scarisbrick, Youn H. Kim, Connor Stonesifer, Cornelis P. Tensen, Larisa J. Geskin, Pietro Quaglino & Egle Ramelyte. (2021) Cutaneous T cell lymphoma. Nature Reviews Disease Primers 7:1.
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Pablo A. Vieyra-Garcia & Peter Wolf. (2021) A deep dive into UV-based phototherapy: Mechanisms of action and emerging molecular targets in inflammation and cancer. Pharmacology & Therapeutics 222, pages 107784.
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Veronica Stolearenco, Trine B. Levring, Helene Myrtue Nielsen, Lise Lindahl, Simon Fredholm, Martin Kongsbak-Wismann, Andreas Willerslev-Olsen, Terkild B. Buus, Claudia Nastasi, Tengpeng Hu, Maria Gluud, Christophe R.M. Côme, Thorbjørn Krejsgaard, Lars Iversen, Charlotte Menné Bonefeld, Kirsten Grønbæk, Özcan Met, Anders Woetmann, Niels Ødum & Carsten Geisler. (2021) The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma. Dermatology 237:2, pages 283-290.
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Maria Gluud, Simon Fredholm, Edda Blümel, Andreas Willerslev-Olsen, Terkild Brink Buus, Claudia Nastasi, Thorbjørn Krejsgaard, Charlotte Menné Bonefeld, Anders Woetmann, Lars Iversen, Thomas Litman, Carsten Geisler, Niels Ødum & Lise M. Lindahl. (2021) MicroRNA-93 Targets p21 and Promotes Proliferation in Mycosis Fungoides T Cells. Dermatology 237:2, pages 277-282.
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Alexander Salava, Paulina Deptula, Annina Lyyski, Pia Laine, Lars Paulin, Liisa Väkevä, Annamari Ranki, Petri Auvinen & Antti Lauerma. (2020) Skin Microbiome in Cutaneous T-Cell Lymphoma by 16S and Whole-Genome Shotgun Sequencing. Journal of Investigative Dermatology 140:11, pages 2304-2308.e7.
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Veronica Stolearenco, Martin R. J. Namini, Siri S. Hasselager, Maria Gluud, Terkild B. Buus, Andreas Willerslev-Olsen, Niels Ødum & Thorbjørn Krejsgaard. (2020) Cellular Interactions and Inflammation in the Pathogenesis of Cutaneous T-Cell Lymphoma. Frontiers in Cell and Developmental Biology 8.
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Sarah A. Westergaard, Mary Jo Lechowicz, Maggie Harrington, Justin Elsey, Jack L. Arbiser & Mohammad K. Khan. (2020) Induction of remission in a patient with end-stage cutaneous T-cell lymphoma by concurrent use of radiation therapy, gentian violet, and mogamulizumab. JAAD Case Reports 6:8, pages 761-765.
Crossref
Maria Gluud, Andreas Willerslev-Olsen, Lise Mette Rahbek Gjerdrum, Lise M. Lindahl, Terkild B. Buus, Mads Hald Andersen, Charlotte Menne Bonefeld, Thorbjorn Krejsgaard, Ivan V. Litvinov, Lars Iversen, Jürgen C. Becker, Jenny L. Persson, Sergei B. Koralov, Thomas Litman, Carsten Geisler, Anders Woetmann & Niels Odum. (2020) MicroRNAs in the Pathogenesis, Diagnosis, Prognosis and Targeted Treatment of Cutaneous T-Cell Lymphomas. Cancers 12:5, pages 1229.
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Patrick M. Brunner, Constanze Jonak & Robert Knobler. (2020) Recent advances in understanding and managing cutaneous T-cell lymphomas. F1000Research 9, pages 331.
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Malgorzata Bobrowicz, Christina Fassnacht, Desislava Ignatova, Yun-Tsan Chang, Florentia Dimitriou & Emmanuella Guenova. (2020) Pathogenesis and Therapy of Primary Cutaneous T-Cell Lymphoma: Collegium Internationale Allergologicum (CIA) Update 2020. International Archives of Allergy and Immunology 181:10, pages 733-745.
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Tengpeng Hu, Terkild Brink Buus, Thorbjørn Krejsgaard, Anneline Nansen, Betina Kerstin Lundholt, Pieter Spee, Simon Fredholm, David Leander Petersen, Edda Blümel, Maria Gluud, Madalena N. Monteiro, Andreas Willerslev-Olsen, Mads Hald Andersen, Per thor Straten, Özcan Met, Veronica Stolearenco, Hanne Fogh, Robert Gniadecki, Claudia Nastasi, Thomas Litman, Anders Woetmann, Lise Mette Rahbek Gjerdrum & Niels Ødum. (2019) Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome. Oncotarget 10:47, pages 4894-4906.
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