Advanced search
Publication Cover
Human Vaccines & Immunotherapeutics Volume 11, 2015 - Issue 6
Submit an article Journal homepage
1,899
Views
31
CrossRef citations to date
0
Altmetric
Research Paper

Phase II studies to select the formulation of a multivalent HPV L1 virus-like particle (VLP) vaccine

Alain LuxembourgMerck & Co., Inc.; Whitehouse Station, NJ, USACorrespondence[email protected]
,
Darron BrownDepartment of Medicine; Indiana University School of Medicine; Indianapolis, IN, USA
,
Celine BouchardUniversité Laval; Québec, Canada
,
Anna R GiulianoMoffitt Cancer Center; Tampa, FL, USA
,
Ole-Erik IversenDepartment of Clinical Medicine; University of Bergen/Haukeland University Hospital; Bergen, Norway
,
Elmar A JouraMedical University of Vienna; Comprehensive Cancer Center (CCC); Vienna, Austria
,
Mary E PennyInstituto de Investigación Nutricional; Lima, Peru
,
Jaime A RestrepoCentro de Investigation Clinica; Medellin, Colombia
,
Josefina RomagueraUniversity of Puerto Rico; Medical Sciences Campus; San Juan, Puerto Rico
,
Roger MaanssonMerck & Co., Inc.; Whitehouse Station, NJ, USA
,
Erin MoellerMerck & Co., Inc.; Whitehouse Station, NJ, USA
,
Michael RitterMerck & Co., Inc.; Whitehouse Station, NJ, USA
&
Joshua ChenMerck & Co., Inc.; Whitehouse Station, NJ, USA
 show all
Pages 1313-1322 | Received 01 Oct 2014, Accepted 03 Dec 2014, Published online: 18 Jun 2015

Citations (31)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Zheng Quan Toh, Jennie Kosasih, Fiona M Russell, Suzanne M Garland, Edward K Mulholland & Paul V Licciardi. (2019) Recombinant human papillomavirus nonavalent vaccine in the prevention of cancers caused by human papillomavirus. Infection and Drug Resistance 12, pages 1951-1967.
Read now
R. Rupp, D. Hurley, S. Grayson, J. Li, K. Nolan, R.D. McFetridge, J. Hartzel, C. Abeygunawardana, M. Winters, H. Pujar, P. Benner & L. Musey. (2019) A dose ranging study of 2 different formulations of 15-valent pneumococcal conjugate vaccine (PCV15) in healthy infants. Human Vaccines & Immunotherapeutics 15:3, pages 549-559.
Read now
Alain Luxembourg & Erin Moeller. (2017) 9-Valent human papillomavirus vaccine: a review of the clinical development program. Expert Review of Vaccines 16:11, pages 1119-1139.
Read now
Zhigang Zhang, Jun Zhang, Ningshao Xia & Qinjian Zhao. (2017) Expanded strain coverage for a highly successful public health tool: Prophylactic 9-valent human papillomavirus vaccine. Human Vaccines & Immunotherapeutics 13:10, pages 2280-2291.
Read now
Punnee Pitisuttithum, Christine Velicer & Alain Luxembourg. (2015) 9-Valent HPV vaccine for cancers, pre-cancers and genital warts related to HPV. Expert Review of Vaccines 14:11, pages 1405-1419.
Read now

Articles from other publishers (26)

Annamalai RamaAnuja PaiDivya Rosa BarretoSiva Kumar KannanAnup Naha. (2022) Virus-Like particles as a Novel Targeted Drug Delivery Platform for Biomedical Applications. Research Journal of Pharmacy and Technology, pages 2801-2808.
Crossref
Rongdong Huang, Ruihuan Gan, Dongjuan Zhang & Jianxiong Xiao. (2021) The comparative safety of human papillomavirus vaccines: A Bayesian network meta‐analysis. Journal of Medical Virology 94:2, pages 729-736.
Crossref
Kannan Damodharan, Gandarvakottai Senthilkumar Arumugam, Suresh Ganesan, Mukesh Doble & Sathiah Thennarasu. (2021) A comprehensive overview of vaccines developed for pandemic viral pathogens over the past two decades including those in clinical trials for the current novel SARS-CoV-2. RSC Advances 11:33, pages 20006-20035.
Crossref
Courtney Gidengil, Matthew Bidwell Goetz, Sydne Newberry, Margaret Maglione, Owen Hall, Jody Larkin, Aneesa Motala & Susanne Hempel. (2021) Safety of vaccines used for routine immunization in the United States: An updated systematic review and meta-analysis. Vaccine 39:28, pages 3696-3716.
Crossref
Yongle Zhan, Xuan Liu, Yahui Feng, Sansan Wu & Yu Jiang. (2019) Safety and efficacy of human papillomavirus vaccination for people living with HIV: A systematic review and meta-analysis. International Journal of STD & AIDS 30:11, pages 1105-1115.
Crossref
Vanina Alzogaray, Mariela Urrutia, Paula Berguer, Andrés Rossi, Vanesa Zylberman, Romina Pardo, Hernán R. Bonomi & Fernando A. Goldbaum. (2019) Characterization of folding-sensitive nanobodies as tools to study the expression and quality of protein particle immunogens. Journal of Biotechnology 293, pages 17-23.
Crossref
Kyung-Jin Min, Sang-Hoon Kwon, Kidong Kim, Sunghoon Kim, Hyun Jung Kim, Seok Ju Seong, Yong Jung Song, Keun Ho Lee, Shin-Wha Lee, Jeong-Won Lee, Suk-Joon Chang, Woong Ju, Young-Tak Kim & Jae-Kwan Lee. (2019) Clinical guideline for 9-valent HPV vaccine: Korean Society of Gynecologic Oncology Guideline. Journal of Gynecologic Oncology 30:2.
Crossref
Paolo Bonanni, Beatrice Zanella, Francesca Santomauro, Chiara Lorini, Angela Bechini & Sara Boccalini. (2018) Safety and perception: What are the greatest enemies of HPV vaccination programmes?. Vaccine 36:36, pages 5424-5429.
Crossref
S M Garland, P Pitisuttithum, H Y S Ngan, C -H Cho, C -Y Lee, C -A Chen, Y C Yang, T -Y Chu, N -F Twu, R Samakoses, Y Takeuchi, T H Cheung, S C Kim, L -M Huang, B -G Kim, Y -T Kim, K -H Kim, Y -S Song, S Lalwani, J -H Kang, M Sakamoto, H -S Ryu, N Bhatla, H Yoshikawa, M C Ellison, S R Han, E Moeller, S Murata, M Ritter, M Sawata, C Shields, A Walia, G Perez & A Luxembourg. (2018) Efficacy, Immunogenicity, and Safety of a 9-Valent Human Papillomavirus Vaccine: Subgroup Analysis of Participants From Asian Countries. The Journal of Infectious Diseases 218:1, pages 95-108.
Crossref
Ángela María Ruiz-Sternberg, Edson D. MoreiraJrJr, Jaime A. Restrepo, Eduardo Lazcano-Ponce, Robinson Cabello, Arnaldo Silva, Rosires Andrade, Francisco Revollo, Santos Uscanga, Alejandro Victoria, Ana María Guevara, Joaquín Luna, Manuel Plata, Claudia Nossa Dominguez, Edison Fedrizzi, Eugenio Suarez, Julio C. Reina, Misoo C. Ellison, Erin Moeller, Michael Ritter, Christine Shields, Miguel Cashat, Gonzalo Perez & Alain Luxembourg. (2018) Efficacy, immunogenicity, and safety of a 9-valent human papillomavirus vaccine in Latin American girls, boys, and young women. Papillomavirus Research 5, pages 63-74.
Crossref
Marc Arbyn, Lan Xu, Cindy Simoens & Pierre PL Martin-Hirsch. (2018) Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors. Cochrane Database of Systematic Reviews 2020:3.
Crossref
Yung-Taek OuhJae Kwan Lee. (2018) Proposal for cervical cancer screening in the era of HPV vaccination. Obstetrics & Gynecology Science 61:3, pages 298.
Crossref
Warner K Huh, Elmar A Joura, Anna R Giuliano, Ole-Erik Iversen, Rosires Pereira de Andrade, Kevin A Ault, Deborah Bartholomew, Ramon M Cestero, Edison N Fedrizzi, Angelica L Hirschberg, Marie-Hélène Mayrand, Angela Maria Ruiz-Sternberg, Jack T Stapleton, Dorothy J Wiley, Alex Ferenczy, Robert Kurman, Brigitte M Ronnett, Mark H Stoler, Jack Cuzick, Suzanne M Garland, Susanne K Kjaer, Oliver M Bautista, Richard Haupt, Erin Moeller, Michael Ritter, Christine C Roberts, Christine Shields & Alain Luxembourg. (2017) Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16–26 years: a randomised, double-blind trial. The Lancet 390:10108, pages 2143-2159.
Crossref
C. SIGNORELLI, A. ODONE, V. CIORBA, P. CELLA, R. A. AUDISIO, A. LOMBARDI, L. MARIANI, F. S. MENNINI, S. PECORELLI, G. REZZA, G.V. ZUCCOTTI & A. PERACINO. (2017) Human papillomavirus 9-valent vaccine for cancer prevention: a systematic review of the available evidence. Epidemiology and Infection 145:10, pages 1962-1982.
Crossref
Lone K. Petersen, Jaime Restrepo, Edson D. MoreiraJr.Jr., Ole-Erik Iversen, Punnee Pitisuttithum, Pierre Van Damme, Elmar A. Joura, Sven-Erik Olsson, Daron Ferris, Stan Block, Anna R. Giuliano, Xavier Bosch, Sophie Pils, Jack Cuzick, Suzanne M. Garland, Warner Huh, Susanne K. Kjaer, Oliver M. Bautista, Donna Hyatt, Roger Maansson, Erin Moeller, Hong Qi, Christine Roberts & Alain Luxembourg. (2017) Impact of baseline covariates on the immunogenicity of the 9-valent HPV vaccine – A combined analysis of five phase III clinical trials. Papillomavirus Research 3, pages 105-115.
Crossref
Fei Yin, Yajun Wang, Na Chen, Dunquan Jiang, Yefeng Qiu, Yan Wang, Mei Yan, Jianping Chen, Haijiang Zhang & Yongjiang Liu. (2017) A novel trivalent HPV 16/18/58 vaccine with anti-HPV 16 and 18 neutralizing antibody responses comparable to those induced by the Gardasil quadrivalent vaccine in rhesus macaque model. Papillomavirus Research 3, pages 85-90.
Crossref
Ulrike Wieland. (2017) Impfung birgt großes Potenzial. Der Deutsche Dermatologe 65:4, pages 272-284.
Crossref
Edmund K Hainisch, Hans Abel-Reichwald, Saeed Shafti-Keramat, Barbara Pratscher, Annunziata Corteggio, Giuseppe Borzacchiello, Maria Wetzig, Christoph Jindra, Alexander Tichy, Reinhard Kirnbauer & Sabine Brandt. (2017) Potential of a BPV1 L1 VLP vaccine to prevent BPV1- or BPV2-induced pseudo-sarcoid formation and safety and immunogenicity of EcPV2 L1 VLPs in horse. Journal of General Virology 98:2, pages 230-241.
Crossref
Alain Luxembourg, Susanne K. Kjaer, Mari Nygard, Misoo C. Ellison, Thomas Group, J. Brooke Marshall, David Radley & Alfred Saah. (2017) Design of a long-term follow-up effectiveness, immunogenicity and safety study of women who received the 9-valent human papillomavirus vaccine. Contemporary Clinical Trials 52, pages 54-61.
Crossref
Kate McKeage & Katherine A. Lyseng-Williamson. (2016) 9-Valent human papillomavirus recombinant vaccine (Gardasil® 9): a guide to its use in the EU. Drugs & Therapy Perspectives 32:10, pages 414-421.
Crossref
Lina Wang, Pengyan Wang, Yan Ren, Jingyun Du, Jianjun Jiang, Xuesong Jia, Chuangfu Chen & Yuanzhi Wang. (2016) Prevalence of High-Risk Human Papillomavirus (HR-HPV) Genotypes and Multiple Infections in Cervical Abnormalities from Northern Xinjiang, China. PLOS ONE 11:8, pages e0160698.
Crossref
Edson D. MoreiraJrJrStan L. BlockDaron FerrisAnna R. GiulianoOle-Erik IversenElmar A. JouraPope KosalaraksaAndrea SchillingPierre Van DammeJacob BornsteinF. Xavier BoschSophie PilsJack CuzickSuzanne M. GarlandWarner HuhSusanne K. KjaerHong Qi, Donna Hyatt, Jason Martin, Erin Moeller, Michael Ritter, Martine Baudin & Alain Luxembourg. (2016) Safety Profile of the 9-Valent HPV Vaccine: A Combined Analysis of 7 Phase III Clinical Trials. Pediatrics 138:2.
Crossref
Julia M.L. Brotherton, Mark Jit, Patti E. Gravitt, Marc Brisson, Aimée R. Kreimer, Sara I. Pai, Carole Fakhry, Joseph Monsonego & Silvia Franceschi. (2016) Eurogin Roadmap 2015: How has HPV knowledge changed our practice: Vaccines. International Journal of Cancer 139:3, pages 510-517.
Crossref
Pierre Van Damme, Chris J.L.M. Meijer, Dorothee Kieninger, Anne Schuyleman, Stephane Thomas, Alain Luxembourg & Martine Baudin. (2016) A phase III clinical study to compare the immunogenicity and safety of the 9-valent and quadrivalent HPV vaccines in men. Vaccine 34:35, pages 4205-4212.
Crossref
Janine T Bryan, Barry Buckland, Jennifer Hammond & Kathrin U Jansen. (2016) Prevention of cervical cancer: journey to develop the first human papillomavirus virus-like particle vaccine and the next generation vaccine. Current Opinion in Chemical Biology 32, pages 34-47.
Crossref
S. Pils & E.A. Joura. (2015) From the monovalent to the nine-valent HPV vaccine. Clinical Microbiology and Infection 21:9, pages 827-833.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.