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The potential impact of pneumococcal conjugate vaccine in Africa: Considerations and early lessons learned from the South African experience

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Pages 314-325 | Received 15 Jun 2015, Accepted 14 Aug 2015, Published online: 23 Feb 2016

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JP Sevilla, Daria Burnes, Rehab Zakaria El Saie, Hammam Haridy, Matt Wasserman, Sarah Pugh, Johnna Perdrizet & David Bloom. (2022) Cost-utility and cost-benefit analysis of pediatric PCV programs in Egypt. Human Vaccines & Immunotherapeutics 18:6.
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Marta C. Nunes, Marta Moreira, Anthonet Koen, Nadia van Niekerk, Lisa Jose, Clare L. Cutland, Nancy François, Sonia Schoonbroodt, Javier Ruiz-Guiñazú, Juan Pablo Yarzabal, Dorota Borys, Lode Schuerman & Shabir A. Madhi. (2020) Bacterial nasopharyngeal carriage following infant immunization with pneumococcal conjugate vaccines according to a 2+1 schedule in children in South Africa: an exploratory analysis of two clinical trials. Expert Review of Vaccines 19:12, pages 1177-1189.
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Deus Thindwa, Amy Pinsent, John Ojal, Katherine E Gallagher, Neil French & Stefan Flasche. (2020) Vaccine strategies to reduce the burden of pneumococcal disease in HIV-infected adults in Africa.. Expert Review of Vaccines 19:11, pages 1085-1092.
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Shabir A Madhi, Anthonet Koen, Lisa Jose, Marta Moreira, Nadia van Niekerk, Clare Cutland, Nancy François, Javier Ruiz-Guiñazú, Juan Pablo Yarzabal, Dorota Borys & Lode Schuerman. (2017) Immunization with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) according to different schedules in infants in South Africa: a phase III trial. Expert Review of Vaccines 16:6, pages 641-656.
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Robert Cohen, Jérémie François Cohen, Martin Chalumeau & Corinne Levy. (2017) Impact of pneumococcal conjugate vaccines for children in high- and non–high-income countries. Expert Review of Vaccines 16:6, pages 625-640.
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Maimuna Carrim, Stefano Tempia, Deus Thindwa, Neil A Martinson, Kathleen Kahn, Stefan Flasche, Orienka Hellferscee, Florette K Treurnicht, Meredith L McMorrow, Jocelyn Moyes, Thulisa Mkhencele, Azwifarwi Mathunjwa, Jackie Kleynhans, Limakatso Lebina, Katlego Mothlaoleng, Floidy Wafawanaka, Francesc Xavier Gómez-Olivé, Cheryl Cohen, Anne von Gottberg & Nicole Wolter. (2023) Unmasking Pneumococcal Carriage in a High Human Immunodeficiency Virus (HIV) Prevalence Population in two Community Cohorts in South Africa, 2016–2018: The PHIRST Study. Clinical Infectious Diseases 76:3, pages e710-e717.
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Tianjing Hu, David F. Miller, Amber W. Taylor, Christine Riley, Caitlin McCormick, Keely N. Thomas, Rachel Y. Gao, Kathy L. Rowlen, Emilia B. Byrne, Pardeep Kumar, Soo Kyung Kim & Erica D. Dawson. (2022) 30-Minute Highly Multiplexed VaxArray Immunoassay for Pneumococcal Vaccine Antigen Characterization. Vaccines 10:11, pages 1964.
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Nida Javaid, Courtney Olwagen, Susan Nzenze, Paulina Hawkins, Rebecca Gladstone, Lesley McGee, Robert F. Breiman, Stephen D. Bentley, Shabir A. Madhi & Stephanie Lo. (2022) Population genomics of pneumococcal carriage in South Africa following the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) immunization. Microbial Genomics 8:6.
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Aquino Albino Nhantumbo, Charlotte Elizabeth Comé, Plácida Iliany Maholela, Alcides Moniz Munguambe, Paulino da Costa, Mariana Mott, Gabriella Rosa Cunha, Lúcia Chambal, Cícero Dias, Vlademir Vicente Cantarelli & Eduardo Samo Gudo. (2022) Etiology of meningitis among adults in three quaternary hospitals in Mozambique, 2016–2017: The role of HIV. PLOS ONE 17:5, pages e0267949.
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Regina E. Abotsi, Mark P. Nicol, Grace McHugh, Victoria Simms, Andrea M. Rehman, Charmaine Barthus, Slindile Mbhele, Brewster W. Moyo, Lucky G. Ngwira, Hilda Mujuru, Beauty Makamure, Justin Mayini, Jon Ø. Odland, Rashida A. Ferrand & Felix S. Dube. (2021) Prevalence and antimicrobial resistance profiles of respiratory microbial flora in African children with HIV-associated chronic lung disease. BMC Infectious Diseases 21:1.
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Theano Lagousi, Ioanna Papadatou, Petros Strempas, Elena Chatzikalil & Vana Spoulou. (2021) Pneumococcal Immunization Strategies for High-Risk Pediatric Populations Worldwide: One Size Does Not Fit All. Vaccines 9:12, pages 1390.
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Kaunda Yamba, Evans Mpabalwani, Ruth Nakazwe, Evans Mulendele, Goitom Weldegebriel, Jason M Mwenda, Reggis Katsande, Linda de Gouveia, Elizabeth Chizema-Kawesha, Raphael Chanda, Belem Matapo, James C L Mwansa & Chileshe Lukwesa-Musyani. (2021) The Burden of Invasive Bacterial Disease and the Impact of 10-Valent Pneumococcal Conjugate Vaccine in Children <5 years hospitalized for Meningitis in Lusaka, Zambia, 2010–2019. The Journal of Infectious Diseases 224:Supplement_3, pages S275-S284.
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John Njuma Libwea, Kirsi Gröndahl-Yli-Hannuksela, Marie Kobela, Maija Toropainen, Outi Nyholm, Paul Koki Ndombo, Sinata Koulla-Shiro, Hanna Nohynek, J. Pekka Nuorti, Jaana Vuopio & Arto A. Palmu. (2020) Prevalence of pneumococcal nasopharyngeal colonization and serotypes circulating in Cameroonian children after the 13-valent pneumococcal conjugate vaccine introduction. International Journal of Infectious Diseases 98, pages 113-120.
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Lawson Ung, Paulo J. M. Bispo, Noelle C. Bryan, Camille Andre, James Chodosh & Michael S. Gilmore. (2019) The Best of All Worlds: Streptococcus pneumoniae Conjunctivitis through the Lens of Community Ecology and Microbial Biogeography. Microorganisms 8:1, pages 46.
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Bikas K. Arya, Sangeeta Das Bhattacharya, Gautam Harigovind, Ranjan S. Das, Tila Khan, Feroze Ganaie, Swapan K. Niyogi, K. L. Ravikumar, Anand Manoharan, Subhasish Bhattacharyya, Samiran Panda, Sutapa Mandal & Banuja Acharya. (2019) Streptococcus pneumoniae Acquisition and Carriage in Vaccine Naïve Indian Children with HIV and their Parents: A Longitudinal Household Study. The Indian Journal of Pediatrics 86:11, pages 1002-1010.
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Mouhamadou A Sonko, Felix S Dube, Catherine Bi Okoi, Amadou Diop, Aliou Thiongane, Madikay Senghore, Peter Ndow, Archibal Worwui, Papa M Faye, Baidy Dieye, Idrissa D Ba, Aliou Diallo, Diop Boly, Ousmane Ndiaye, Moussa F Cissé, Jason M Mwenda, Brenda A Kwambana-Adams & Martin Antonio. (2019) Changes in the Molecular Epidemiology of Pediatric Bacterial Meningitis in Senegal After Pneumococcal Conjugate Vaccine Introduction. Clinical Infectious Diseases 69:Supplement_2, pages S156-S163.
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Bakary Sanneh, Catherine Okoi, Mary Grey-Johnson, Haddy Bah-Camara, Baba Kunta Fofana, Ignatius Baldeh, Alhagie Papa Sey, Mahamadou Labbo Bah, Mamadi Cham, Amadou Samateh, Effua Usuf, Peter Sylvanus Ndow, Madikay Senghore, Archibald Worwui, Jason M Mwenda, Brenda Kwambana-Adams & Martin Antonio. (2019) Declining Trends of Pneumococcal Meningitis in Gambian Children After the Introduction of Pneumococcal Conjugate Vaccines. Clinical Infectious Diseases 69:Supplement_2, pages S126-S132.
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Catherine Boni-Cisse, Sheikh Jarju, Rowan E Bancroft, Nicaise A Lepri, Hamidou Kone, N’zue Kofi, Alice Britoh-Mlan, Flore Sandrine Zaba, Effua Usuf, Peter Sylvanus Ndow, Archibald Worwui, Jason M Mwenda, Joseph N Biey, Bernard Ntsama, Brenda A Kwambana-Adams & Martin Antonio. (2019) Etiology of Bacterial Meningitis Among Children <5 Years Old in Côte d’Ivoire: Findings of Hospital-based Surveillance Before and After Pneumococcal Conjugate Vaccine Introduction. Clinical Infectious Diseases 69:Supplement_2, pages S114-S120.
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Enyonam Tsolenyanu, Rowan E Bancroft, Abdul K Sesay, Madikay Senghore, Mawouto Fiawoo, Djatougbe Akolly, Mawussi A Godonou, Novissi Tsogbale, Segla D Tigossou, Leopold Tientcheu, Anoumou Dagnra, Yawo Atakouma, Peter Sylvanus Ndow, Archibald Worwui, Dadja E Landoh, Jason M Mwenda, Joseph N Biey, Bernard Ntsama, Brenda A Kwambana-Adams & Martin Antonio. (2019) Etiology of Pediatric Bacterial Meningitis Pre- and Post-PCV13 Introduction Among Children Under 5 Years Old in Lomé, Togo. Clinical Infectious Diseases 69:Supplement_2, pages S97-S104.
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A.B. Ibarz-Pavon & N. French. (2018) No changes on viral load and CD4+ T-cell counts following immunization with 7-valent pneumococcal conjugate vaccine among HIV-infected adults in Malawi. Vaccine 36:19, pages 2504-2506.
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Susan A. Nzenze, Shabir A. Madhi, Tinevimbo Shiri, Keith P. Klugman, Linda de Gouveia, David P. Moore, Alan S. Karstaedt, Stefano Tempia, Marta C. Nunes & Anne von Gottberg. (2017) Imputing the Direct and Indirect Effectiveness of Childhood Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease by Surveying Temporal Changes in Nasopharyngeal Pneumococcal Colonization. American Journal of Epidemiology 186:4, pages 435-444.
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Robert Cohen & Corinne Levy. (2017) 13-valent pneumococcal conjugate vaccine in Africa. The Lancet Global Health 5:3, pages e244-e245.
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