8,385
Views
29
CrossRef citations to date
0
Altmetric
Review

Subcutaneous vaccine administration – an outmoded practice

Pages 1329-1341 | Received 15 Mar 2020, Accepted 17 Aug 2020, Published online: 29 Sep 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Dylan A. Hendy, Alex Haven, Eric M. Bachelder & Kristy M. Ainslie. (2023) Preclinical developments in the delivery of protein antigens for vaccination. Expert Opinion on Drug Delivery 20:3, pages 367-384.
Read now
Yasunori Ishihara, Haruo Kuroki, Hidenobu Hidaka, Kazuyuki Iwai, Keiko Wan, Masayoshi Shirakawa & Miyuki Sawata. (2023) Safety and immunogenicity of a 15-valent pneumococcal conjugate vaccine in Japanese healthy infants: A Phase I study (V114-028). Human Vaccines & Immunotherapeutics 19:1.
Read now
Ian F. Cook. (2022) Minimizing shoulder injury related to vaccine administration. Human Vaccines & Immunotherapeutics 18:1, pages 1-2.
Read now

Articles from other publishers (25)

Marjan Doppen, Ciléin Kearns, Thomas Hills, Mark Weatherall & Richard Beasley. (2024) Intramuscular vaccination needle length: a call to arms. The Lancet 403:10426, pages 528-529.
Crossref
Chutima Seree-aphinan, Ploysyne Rattanakaemakorn, Poonkiat Suchonwanit, Kunlawat Thadanipon, Yanisa Ratanapokasatit, Tanat Yongpisarn, Kumthorn Malathum, Pornchai Simaroj, Chavachol Setthaudom, Onchuma Lohjai, Somsak Tanrattanakorn & Kumutnart Chanprapaph. (2024) Immunogenicity of Intradermal Versus Intramuscular BNT162b2 COVID-19 Booster Vaccine in Patients with Immune-Mediated Dermatologic Diseases: A Non-Inferiority Randomized Controlled Trial. Vaccines 12:1, pages 73.
Crossref
Teeranan Laohawiriyakamol, Pattira Boonsri, Khetnathee Phutphithak, Thamonchanok Niyomkarn, Prapakorn Klabklay & Chaiwat Chuaychoosakoon. (2023) Appropriate intradeltoid muscle needle penetration depth in vaccine administration: an MRI study in Thailand. Frontiers in Immunology 14.
Crossref
Kin Man Au, Justin E. Wilson, Jenny P.-Y. Ting & Andrew Z. Wang. (2023) An injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis. Nature Biomedical Engineering.
Crossref
Branden Lee, Etsuro Nanishi, Ofer Levy & David J. Dowling. (2023) Precision Vaccinology Approaches for the Development of Adjuvanted Vaccines Targeted to Distinct Vulnerable Populations. Pharmaceutics 15:6, pages 1766.
Crossref
Eriko Itoh, Sakiko Shimizu, Yasushi Ami, Yoichiro Iwase & Yuichi Someya. (2023) Dose-sparing effect of Sabin-derived inactivated polio vaccine produced in Japan by intradermal injection device for rats. Biologicals 82, pages 101677.
Crossref
Marjan Doppen, Ciléin Kearns, Mark Weatherall, Nethmi Kearns, Peter McIntyre, Thomas Hills & Richard Beasley. (2023) When should a longer needle be used for intramuscular injection in obese patients? A combined analysis of New Zealand data. Vaccine 41:16, pages 2690-2695.
Crossref
Marjan Doppen, Ali Mirjalili, Matire Harwood, Allie Eathorne, Irene Braithwaite, Jonathan Bong, Louis Kirton, Ruth Semprini, Mark Weatherall, Alex Semprini, Ciléin Kearns, Melissa Black, Stacey Kung, Michaela Walton, Richard Beasley & Thomas Hills. (2023) COVID-19 vaccination and the skin to deltoid muscle distance in adults with diabetes. Vaccine: X 13, pages 100248.
Crossref
Allegra Peletta, Céline Lemoine, Thomas Courant, Nicolas Collin & Gerrit Borchard. (2023) Meeting vaccine formulation challenges in an emergency setting: Towards the development of accessible vaccines. Pharmacological Research 189, pages 106699.
Crossref
Ciléin Kearns, Claire Houghton, Emily Dickinson, Lee Hatter, Pepa Bruce, Srinidhi Krishnamoorthy, Mark Weatherall, Thomas Hills, Marjan Doppen, Seyed Ali Mirjalili & Richard Beasley. (2023) What variables should inform needle length choice for deltoid intramuscular injection? A systematic review. BMJ Open 13:1, pages e063530.
Crossref
Muhammad Afzal, Imran Kazmi, Rupinder Kaur, Salman Bakr I. Hosawi, Mohammed Kaleem, Sami I. Alzarea & Muhammad Masood Ahmad. 2023. How Synthetic Drugs Work. How Synthetic Drugs Work 1 25 .
Fernando Isidro Lago-Deibe, Mercedes Valladares-Cabaleiro, María José Fernández-Domínguez, Isabel Fernández-Fernández, Ana Clavería, Sara Rodríguez-Pastoriza, Javier Roca-Pardinas & María Victoria Martín-Miguel. (2022) Effectiveness and safety of tetanus vaccine administration by intramuscular vs. subcutaneous route in anticoagulated patients: Randomized clinical trial in primary care. Frontiers in Medicine 9.
Crossref
Amla Chopra & Archi Gupta. (2022) Skin as an immune organ and the site of biomimetic, non-invasive vaccination. Medicine in Novel Technology and Devices 16, pages 100196.
Crossref
Andreas Tiede, Hendrik Leise, Silvia Horneff, Johannes Oldenburg, Susan Halimeh, Christine Heller, Christoph Königs, Katharina Holstein & Christian Pfrepper. (2022) Safety of intramuscular COVID‐19 vaccination in patients with haemophilia. Haemophilia 28:5, pages 687-693.
Crossref
Thomas Hills, Aimee Paterson, Rebecca Woodward, Francis Middleton, Lauren H. Carlton, Reuben McGregor, Sebastien Barfoot, Ciara Ramiah, Alana L. Whitcombe, Victor M. Zimbron, David Mahuika, Joshua Brown, Kate Palmer-Neels, Brittany Manning, Devanshi Jani, Brooke Reeves, Georgia T. Whitta, Susan Morpeth, Richard Beasley, Mark Weatherall, Anthony Jordan, Peter McIntyre, Nicole J. Moreland & S. Ali Mirjalili. (2022) The effect of needle length and skin to deltoid muscle distance in adults receiving an mRNA COVID-19 vaccine. Vaccine 40:33, pages 4827-4834.
Crossref
Abhijita Talukder, Chayanika Kalita, Nayanika Neog, Chayanika Goswami, Mrinal Kashyap Sarma & Iswar Hazarika. (2022) A comparative analysis on the safety and efficacy of Covaxin versus other vaccines against COVID-19: a review. Zeitschrift für Naturforschung C 77:7-8, pages 351-362.
Crossref
Lijun Bian, Yu Zheng, Xiaohong Guo, Dongdong Li, Jingying Zhou, Linyao Jing, Yan Chen, Jingcai Lu, Ke Zhang, Chunlai Jiang, Yong Zhang & Wei Kong. (2022) Intramuscular Inoculation of AS02-Adjuvanted Respiratory Syncytial Virus (RSV) F Subunit Vaccine Shows Better Efficiency and Safety Than Subcutaneous Inoculation in BALB/c Mice. Frontiers in Immunology 13.
Crossref
Ayesa Syenina, Esther S. Gan, Justin Z. N. Toh, Ruklanthi de Alwis, Lowell Z. Lin, Christine Y. L. Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L. E. Wee, Dorothy H. L. Ng, Kuan Rong Chan, Jean X. Y. Sim, Shirin Kalimuddin, Eugenia Z. Ong, Jenny G. Low & Eng Eong Ooi. (2022) Adverse effects following anti–COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes. PLOS Biology 20:5, pages e3001643.
Crossref
Wang‐Sheng Lin, David Killeen & Chen‐Ya Yang. (2021) Point‐of‐Care Ultrasound Is a Valuable Modality During Mass COVID ‐19 Vaccination Campaigns . Journal of Ultrasound in Medicine 41:5, pages 1295-1297.
Crossref
Andrew W. Ambler & Benjamin D. Brooks. 2022. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions. A Worldwide Yearly Survey of New Data in Adverse Drug Reactions 341 364 .
Matthias Karer, Karin Stiasny, Markus Zeitlinger & Bernd Jilma. (2021) Subcutaneous injection of mRNA vaccines against severe acute respiratory syndrome coronavirus 2: an option for severe bleeding disorders or anticoagulated patients?. Blood Coagulation & Fibrinolysis 32:6, pages 423-424.
Crossref
Nimrod Rahamimov, Veronica Baturov, Adi Shani, Ilai Ben Zoor, Doron Fischer & Anna Chernihovsky. (2021) Inadequate deltoid muscle penetration and concerns of improper COVID mRNA vaccine administration can be avoided by injection technique modification. Vaccine 39:37, pages 5326-5330.
Crossref
Alan Walker. (2021) You know where you can stick that … or do you? Where to inject the deltoid and why. Practice Nursing 32:5, pages 189-194.
Crossref
Andrew W. Ambler, Francina D. Towne & Benjamin D. Brooks. 2021. 355 374 .
Ayesa Syenina, Esther S. Gan, Justin ZN Toh, Ruklanthi de Alwis, Lowell Z. Lin, Christine YL Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L.E. Wee, Dorothy H.L. Ng, Chan Rong, Jean XY Sim, Shirin Kalimuddin, Eugenia Z. Ong, Jenny G. Low & Eng Eong Ooi. (2021) Baseline Enrichment of T and NK Cell Genes Predispose to mRNA Vaccine-Associated Systemic Adverse Events that Can Be Alleviated by Altering the Route of Vaccination. SSRN Electronic Journal.
Crossref