719
Views
263
CrossRef citations to date
0
Altmetric
Research Article

Induction of xenobiotic enzymes by the map kinase pathway and the antioxidant or electrophile response element (ARE/EpRE),†,

, , , , , & show all
Pages 255-271 | Published online: 04 Mar 2002

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Hidetomo Iwano, Wakako Ujita, Miyu Nishikawa, Satomi Ishii, Hiroki Inoue & Hiroshi Yokota. (2014) Effect of dietary eugenol on xenobiotic metabolism and mediation of UDP-glucuronosyltransferase and cytochrome P450 1A1 expression in rat liver. International Journal of Food Sciences and Nutrition 65:2, pages 241-244.
Read now
D. Kalpana Deepa Priya, R. Gayathri, G. R. Gunassekaran, S. Murugan & D. Sakthisekaran. (2013) Apoptotic role of natural isothiocyanate from broccoli (Brassica oleracea italica) in experimental chemical lung carcinogenesis. Pharmaceutical Biology 51:5, pages 621-628.
Read now
Teruo Hayashi, Shang-Yi Tsai, Tomohisa Mori, Michiko Fujimoto & Tsung-Ping Su. (2011) Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders. Expert Opinion on Therapeutic Targets 15:5, pages 557-577.
Read now
Ichiro SHIRASUGI, Miyuki KAMADA, Takashi MATSUI, Yoichi SAKAKIBARA, Ming-Cheh LIU & Masahito SUIKO. (2010) Sulforaphane Inhibited Melanin Synthesis by Regulating Tyrosinase Gene Expression in B16 Mouse Melanoma Cells. Bioscience, Biotechnology, and Biochemistry 74:3, pages 579-582.
Read now
Stephanie J. Webb, Thomas E. Geoghegan, Russell A. Prough & Kristy K. Michael Miller. (2006) The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors. Drug Metabolism Reviews 38:1-2, pages 89-116.
Read now

Articles from other publishers (257)

Xiaoqing Li, Ningzi Zang, Nan Zhang, Lijian Pang, Ling Lv, Xiansheng Meng, Xiaodong Lv & Jiapeng Leng. (2023) DNA damage resulting from human endocrine disrupting chemical exposure: Genotoxicity, detection and dietary phytochemical intervention. Chemosphere, pages 139522.
Crossref
Taotao Wang, Hong Xu, Shanshan Wu, Yuanxin Guo, Guangshan Zhao & Dongxu Wang. (2023) Mechanisms Underlying the Effects of the Green Tea Polyphenol EGCG in Sarcopenia Prevention and Management. Journal of Agricultural and Food Chemistry 71:25, pages 9609-9627.
Crossref
Chao Tang, Jiaqi Han, Dan Chen, Shuai Zong, Jun Liu, Juan Kan, Chunlu Qian & Changhai Jin. (2023) Recent advances on the biological activities of purple sweet potato anthocyanins. Food Bioscience 53, pages 102670.
Crossref
Wei Jin, Chunrun Li, Shihui Yang, Shiyi Song, Weiwei Hou, Yang Song & Quanyu Du. (2023) Hypolipidemic effect and molecular mechanism of ginsenosides: a review based on oxidative stress. Frontiers in Pharmacology 14.
Crossref
Mohammad Imran, Areeba Insaf, Nazeer Hasan, Vrushabh V. Sugandhi, Deumaya Shrestha, Keshav Raj Paudel, Saurav Kumar Jha, Philip M. Hansbro, Kamal Dua, Hari Prasad Devkota & Yousuf Mohammed. (2023) Exploring the Remarkable Chemotherapeutic Potential of Polyphenolic Antioxidants in Battling Various Forms of Cancer. Molecules 28:8, pages 3475.
Crossref
Yuhan Sheng, Yizhuo Sun, Yang Tang, Yanru Yu, Jiarou Wang, Fengjie Zheng, Yuhang Li & Yan Sun. (2023) Catechins: Protective mechanism of antioxidant stress in atherosclerosis. Frontiers in Pharmacology 14.
Crossref
Monika Aggarwal. (2023) 2,2-Diphenethyl Isothiocyanate Enhances Topoisomerase Inhibitor-Induced Cell Death and Suppresses Multi-Drug Resistance 1 in Breast Cancer Cells. Cancers 15:3, pages 928.
Crossref
Tetsuro Ishii, Eiji Warabi & Giovanni E. Mann. (2023) Stress Activated MAP Kinases and Cyclin-Dependent Kinase 5 Mediate Nuclear Translocation of Nrf2 via Hsp90α-Pin1-Dynein Motor Transport Machinery. Antioxidants 12:2, pages 274.
Crossref
Pei-Tzu Yen, Shang-En Huang, Jong-Hau Hsu, Cheng-Hsiang Kuo, Yu-Ying Chao, Lung-Shuo Wang & Jwu-Lai Yeh. (2022) Anti-Inflammatory and Anti-oxidative Effects of Puerarin in Postmenopausal Cardioprotection: Roles of Akt and Heme Oxygenase-1. The American Journal of Chinese Medicine 51:01, pages 149-168.
Crossref
Daniela Mokra, Jana Adamcakova & Juraj Mokry. (2022) Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG): A Time for a New Player in the Treatment of Respiratory Diseases?. Antioxidants 11:8, pages 1566.
Crossref
Victor Neiva Lavorato, Denise Coutinho de Miranda, Filipe Rios Drummond, Leonardo Matheus Teixeira Rezende, Maria do Carmo Gouveia Pelúzio, Marcelo Eustáquio Silva & Antônio José Natali. (2021) Combined action of açai and aerobic exercise training on the development of NAFLD induced by a high-fat diet: a preliminary exploration. Sport Sciences for Health 18:2, pages 509-515.
Crossref
Anyamanee Chaiprasongsuk & Uraiwan Panich. (2022) Role of Phytochemicals in Skin Photoprotection via Regulation of Nrf2. Frontiers in Pharmacology 13.
Crossref
Zhiliang Li, Changchun Feng, Hongjin Dong, Weibin Jin, Wenying Zhang, Jianfeng Zhan & Shuzhen Wang. (2022) Health promoting activities and corresponding mechanism of (–)-epicatechin-3-gallate. Food Science and Human Wellness 11:3, pages 568-578.
Crossref
Mina Homayoonfal, Zatollah Asemi & Bahman Yousefi. (2021) Targeting microRNAs with thymoquinone: a new approach for cancer therapy. Cellular & Molecular Biology Letters 26:1.
Crossref
Michelle van der Merwe, Gustav van Niekerk, Carla Fourie, Manisha du Plessis & Anna-Mart Engelbrecht. (2021) The impact of mitochondria on cancer treatment resistance. Cellular Oncology 44:5, pages 983-995.
Crossref
Zhengde Zhao, Qining Fu, Liangzhu Hu & Yangdong Liu. (2021) Identification of the Crucial Gene in Overflow Arteriovenous Fistula by Bioinformatics Analysis. Frontiers in Physiology 12.
Crossref
You-Cheng Hseu, Yugandhar Vudhya Gowrisankar, Li-Wei Wang, Yan-Zhen Zhang, Xuan-Zao Chen, Pei-Jane Huang, Hung-Rong Yen & Hsin-Ling Yang. (2021) The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Redox Biology 44, pages 102007.
Crossref
Vladimir Burmistrov, Rahul Saxena, Dmitry Pitushkin, Gennady M. Butov, Fung-Lung Chung & Monika Aggarwal. (2021) Adamantyl Isothiocyanates as Mutant p53 Rescuing Agents and Their Structure–Activity Relationships. Journal of Medicinal Chemistry 64:10, pages 6621-6633.
Crossref
Ji-Young Park, Soma Saeidi, Eun-Hee Kim, Do-Hee Kim, Hye-Kyung Na, Joo-Seob Keum & Young-Joon Surh. (2021) Heregulin-β1 Activates NF-E2-related Factor 2 and Induces Manganese Superoxide Dismutase Expression in Human Breast Cancer Cells via Protein Kinase B and Extracellular Signal-regulated Protein Kinase Signaling Pathways. Journal of Cancer Prevention 26:1, pages 54-63.
Crossref
Victor Neiva Lavorato, Denise Coutinho de Miranda, Mauro César Isoldi, Filipe Rios Drummond, Leôncio Lopes Soares, Emily Correna Carlo Reis, Maria do Carmo Gouveia Pelúzio, Maria Lúcia Pedrosa, Marcelo Eustáquio Silva & Antônio José Natali. (2021) Effects of aerobic exercise training and açai supplementation on cardiac structure and function in rats submitted to a high-fat diet. Food Research International 141, pages 110168.
Crossref
Karolina Frączek, Agnieszka Kowalczyk, Martyna Pekala, Kaja Kasarello, Grażyna Sygitowicz, Dorota Sulejczak, Malgorzata Zaremba, Marek Konop, Malgorzata Frankowska, Malgorzata Filip, Magdalena Bujalska-Zadrozny & Patrycja Kleczkowska. (2020) The Positive and Negative Outcome of Morphine and Disulfiram Subacute Co-Administration in Rats in the Absence of Ethanol Challenge. Pharmaceutics 13:1, pages 29.
Crossref
Robert M. Park. (2020) A Simple Toxicokinetic Model Exhibiting Complex Dynamics and Nonlinear Exposure Response. Risk Analysis 40:12, pages 2561-2571.
Crossref
Chaorui Guo, Michael J. Davies & Clare L. Hawkins. (2020) Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages. Redox Biology 36, pages 101666.
Crossref
Manav Gandhi & Sujit Nair. (2020) New vistas in malignant mesothelioma: MicroRNA architecture and NRF2/MAPK signal transduction. Life Sciences 257, pages 118123.
Crossref
Ji Hye Yang, Chang-Su Na, Sam Seok Cho, Kyu Min Kim, Ji Hyun Lee, Xi-Qiang Chen, Sae Kwang Ku, Il Je Cho, Eun Joo KimJe Hyeon LeeSung Hwan Ki. (2020) Hepatoprotective Effect of Neoagarooligosaccharide <i>via</i> Activation of Nrf2 and Enhanced Antioxidant Efficacy. Biological and Pharmaceutical Bulletin 43:4, pages 619-628.
Crossref
Mohammad M. Kamal, Sharmin Akter, Chin-Nu Lin & Sami Nazzal. (2020) Sulforaphane as an anticancer molecule: mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems. Archives of Pharmacal Research 43:4, pages 371-384.
Crossref
Lea Pogačnik, Ajda Ota & Nataša Poklar Ulrih. (2020) An Overview of Crucial Dietary Substances and Their Modes of Action for Prevention of Neurodegenerative Diseases. Cells 9:3, pages 576.
Crossref
Sophie N. B. Selby-Pham, Lee Fong Siow & Louise E. Bennett. (2020) Characterising absorption and health-related properties of phytochemicals extracted from Malaysian palm fruit biomass after oil extraction. Food & Function 11:1, pages 907-920.
Crossref
In‑Hye Kim, Jeong‑Wook Choi & Taek‑Jeong Nam. (2019) PYP1‑4 peptide from Pyropia yezoensis protects against acetaminophen‑induced hepatotoxicity in HepG2 cells. Experimental and Therapeutic Medicine.
Crossref
Monika Aggarwal, Rahul Saxena, Nasir Asif, Elizabeth Sinclair, Judy Tan, Idalia Cruz, Deborah Berry, Bhaskar Kallakury, Quynhchi Pham, Thomas T. Y. Wang & Fung-Lung Chung. (2019) p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition. Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Pandi He, Shikai Yan, Xin Wen, Shuhan Zhang, Zhigang Liu, Xuebo Liu & Chunxia Xiao. (2019) Eriodictyol alleviates lipopolysaccharide‐triggered oxidative stress and synaptic dysfunctions in BV‐2 microglial cells and mouse brain. Journal of Cellular Biochemistry 120:9, pages 14756-14770.
Crossref
Claire D. Munialo, Nenad Naumovski, Domenico Sergi, David Stewart & Duane D. Mellor. (2019) Critical evaluation of the extrapolation of data relative to antioxidant function from the laboratory and their implications on food production and human health: a review. International Journal of Food Science & Technology 54:5, pages 1448-1459.
Crossref
Hye-Lim Jung, Sung-Yong Yang, Min Cheol Pyo, Chung-Oui Hong, Mi-Hyun Nam, Jin-Won Lee & Kwang-Won Lee. (2018) Protective effects of chebulic acid from Terminalia chebula Retz. against t-BHP-induced oxidative stress by modulations of Nrf2 and its related enzymes in HepG2 cells. Food Science and Biotechnology 28:2, pages 555-562.
Crossref
Ester Casanova, Josepa Salvadó, Anna Crescenti & Albert Gibert-Ramos. (2019) Epigallocatechin Gallate Modulates Muscle Homeostasis in Type 2 Diabetes and Obesity by Targeting Energetic and Redox Pathways: A Narrative Review. International Journal of Molecular Sciences 20:3, pages 532.
Crossref
P. García-Pérez, M.E. Barreal, L. Rojo-De Dios, J.F. Cameselle-Teijeiro & P.P. Gallego. 2019. 49 84 .
Ehsan Ghaedi, Nima Rezaei & Maryam Mahmoudi. 2019. Nutrition and Immunity. Nutrition and Immunity 209 281 .
Jingjing Ma, Shuli Li, Longfei Zhu, Sen Guo, Xiuli Yi, Tingting Cui, Yuanmin He, Yuqian Chang, Bangmin Liu, Chunying Li & Zhe Jian. (2018) Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway. Free Radical Biology and Medicine 129, pages 492-503.
Crossref
A'edah Abu‐Bakar, Hao Hu & Matti A. Lang. (2018) Cyp2a5 Promoter‐based Gene Reporter Assay: A Novel Design of Cell‐based Bioassay for Toxicity Prediction . Basic & Clinical Pharmacology & Toxicology 123:S5, pages 72-80.
Crossref
Sharadha Dayalan Naidu, Takafumi Suzuki, Masayuki Yamamoto, Jed W. Fahey & Albena T. Dinkova-Kostova. (2018) Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1. Molecular Nutrition & Food Research 62:18, pages 1700908.
Crossref
Maiquan Li, Tao Xu, Fei Zhou, Mengmeng Wang, Huaxin Song, Xing Xiao & Baiyi Lu. (2018) Neuroprotective Effects of Four Phenylethanoid Glycosides on H2O2-Induced Apoptosis on PC12 Cells via the Nrf2/ARE Pathway. International Journal of Molecular Sciences 19:4, pages 1135.
Crossref
Muthu K. Shanmugam, Frank Arfuso, Alan Prem Kumar, Lingzhi Wang, Boon Cher Goh, Kwang Seok Ahn, Anupam Bishayee & Gautam Sethi. (2018) Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn. Pharmacological Research 129, pages 357-364.
Crossref
Yuxin Wang, Linyao Li, Yawen Wang, Xiaokang Zhu, Mingdong Jiang, Erqun Song & Yang Song. (2018) New application of the commercial sweetener rebaudioside a as a hepatoprotective candidate: Induction of the Nrf2 signaling pathway. European Journal of Pharmacology 822, pages 128-137.
Crossref
Jong-Min Park, Do-Hee Kim, Hye-Kyung Na & Young-Joon Surh. (2016) Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells. Oncotarget 9:3, pages 3014-3028.
Crossref
Shireen Chikara, Lokesh Dalasanur Nagaprashantha, Jyotsana Singhal, David Horne, Sanjay Awasthi & Sharad S. Singhal. (2018) Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment. Cancer Letters 413, pages 122-134.
Crossref
Miriam Martínez-Huélamo, Jose Rodríguez-Morató, Anna Boronat & Rafael de la Torre. (2017) Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection. Antioxidants 6:4, pages 73.
Crossref
Mohammad Mohajeri, Mehdi Rezaee & Amirhossein Sahebkar. (2017) Cadmium-induced toxicity is rescued by curcumin: A review. BioFactors 43:5, pages 645-661.
Crossref
Priti S. Tidke & Chandragouda R. Patil. (2017) Nrf2 activator corosolic acid meliorates alloxan induced diabetic nephropathy in mice. Asian Pacific Journal of Tropical Biomedicine 7:9, pages 797-804.
Crossref
Dora Reglodi, Justine Renaud, Andrea Tamas, Yousef Tizabi, Sergio B. Socías, Elaine Del-Bel & Rita Raisman-Vozari. (2017) Novel tactics for neuroprotection in Parkinson's disease: Role of antibiotics, polyphenols and neuropeptides. Progress in Neurobiology 155, pages 120-148.
Crossref
Sophie Selby-Pham, Jeremy Cottrell, Frank Dunshea, Ken Ng, Louise Bennett & Kate Howell. (2017) Dietary Phytochemicals Promote Health by Enhancing Antioxidant Defence in a Pig Model. Nutrients 9:7, pages 758.
Crossref
Chien-Jen Kao, Wu-Fu Chen, Bo-Lin Guo, Chien-Wei Feng, Han-Chun Hung, Wen-Ya Yang, Chun-Sung Sung, Kuan-Hao Tsui, Hsin Chu, Nan-Fu Chen & Zhi-Hong Wen. (2017) The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity. International Journal of Molecular Sciences 18:5, pages 1096.
Crossref
Hongming Lv, Qinmei Liu, Junfeng Zhou, Guangyun Tan, Xuming Deng & Xinxin Ci. (2017) Daphnetin-mediated Nrf2 antioxidant signaling pathways ameliorate tert-butyl hydroperoxide (t-BHP)-induced mitochondrial dysfunction and cell death. Free Radical Biology and Medicine 106, pages 38-52.
Crossref
Chao Guo, Shiquan Wang, Jialin Duan, Na Jia, Yanrong Zhu, Yi Ding, Yue Guan, Guo Wei, Ying Yin, Miaomaio Xi & Aidong Wen. (2016) Protocatechualdehyde Protects Against Cerebral Ischemia-Reperfusion-Induced Oxidative Injury Via Protein Kinase Cε/Nrf2/HO-1 Pathway. Molecular Neurobiology 54:2, pages 833-845.
Crossref
Sun Woo Jin, Yong Pil Hwang, Chul Yung Choi, Hyung Gyun Kim, Se Jong Kim, Yongan Kim, Young Chul Chung, Kyung Jin Lee, Tae Cheon Jeong & Hye Gwang Jeong. (2017) Protective effect of rutaecarpine against t-BHP-induced hepatotoxicity by upregulating antioxidant enzymes via the CaMKII-Akt and Nrf2/ARE pathways. Food and Chemical Toxicology 100, pages 138-148.
Crossref
Sin-Aye Park, Mee-Hyun Lee, Hye-Kyung Na & Young-Joon Surh. (2016) 4-Hydroxyestradiol induces mammary epithelial cell transformation through Nrf2-mediated heme oxygenase-1 overexpression. Oncotarget 8:1, pages 164-178.
Crossref
Kayoko Kawakami, Chie Moritani, Misugi UrajiAkiko Fujita, Koji Kawakami, Tadashi HatanakaEtsuko Suzaki & Seiji Tsuboi. (2017) Sake lees hydrolysate protects against acetaminophen-induced hepatotoxicity via activation of the Nrf2 antioxidant pathway. Journal of Clinical Biochemistry and Nutrition 61:3, pages 203-209.
Crossref
Neuza Mariko, Aymoto Hassimotto & Franco Maria Lajolo. 2017. Global Food Security and Wellness. Global Food Security and Wellness 105 124 .
Lidong Wang, Songling Zhang, Hang Cheng, Hongming Lv, Genhong Cheng & Xinxin Ci. (2016) Nrf2-mediated liver protection by esculentoside A against acetaminophen toxicity through the AMPK/Akt/GSK3β pathway. Free Radical Biology and Medicine 101, pages 401-412.
Crossref
Bárbara S. Rocha, Carla Nunes & João Laranjinha. (2016) Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome. The International Journal of Biochemistry & Cell Biology 81, pages 393-402.
Crossref
Keryn Woodman, Chantal Coles, Shireen Lamandé & Jason White. (2016) Nutraceuticals and Their Potential to Treat Duchenne Muscular Dystrophy: Separating the Credible from the Conjecture. Nutrients 8:11, pages 713.
Crossref
M Aggarwal, R Saxena, E Sinclair, Y Fu, A Jacobs, M Dyba, X Wang, I Cruz, D Berry, B Kallakury, S C Mueller, S D Agostino, G Blandino, M L Avantaggiati & F-L Chung. (2016) Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth. Cell Death & Differentiation 23:10, pages 1615-1627.
Crossref
Muthu K Shanmugam, Jong Hyun Lee, Edna Zhi Pei Chai, Madhu Mathi Kanchi, Shreya Kar, Frank Arfuso, Arunasalam Dharmarajan, Alan Prem Kumar, Perumal Samy Ramar, Chung Yeng Looi, Mohammad Rais Mustafa, Vinay Tergaonkar, Anupam Bishayee, Kwang Seok Ahn & Gautam Sethi. (2016) Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds. Seminars in Cancer Biology 40-41, pages 35-47.
Crossref
Min Ji Bak, Van-Long Truong, Se-Yeon Ko, Xuan Ngan Giang Nguyen, Mira Jun, Soon-Gi Hong, Jong-Won Lee & Woo-Sik Jeong. (2016) Induction of Nrf2/ARE-mediated cytoprotective genes by red ginseng oil through ASK1?MKK4/7?JNK and p38 MAPK signaling pathways in HepG2 cells. Journal of Ginseng Research 40:4, pages 423-430.
Crossref
Lidong Wang, Xinxin Ci, Hongming Lv, Xiaosong Wang, F Xiaofeng Qin & Genhong Cheng. (2016) Isotetrandrine ameliorates tert-butyl hydroperoxide-induced oxidative stress through upregulation of heme oxygenase-1 expression. Experimental Biology and Medicine 241:14, pages 1568-1576.
Crossref
Takemi Yoshida, Takashi Ashino & Yasuna Kobayashi. (2016) Chemical-induced coordinated and reciprocal changes in heme metabolism, cytochrome P450 synthesis and others in the liver of humans and rodents. The Journal of Toxicological Sciences 41:Special, pages SP89-SP103.
Crossref
Sangeetha Sukumari-Ramesh, Niyathi Prasad, Cargill H AlleyneJrJr, John R Vender & Krishnan M Dhandapani. (2015) Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells. BMC Cancer 15:1.
Crossref
Ajeet Kumar Verma, Arti Yadav, Jayant Dewangan, Sarvendra Vikram Singh, Manisha Mishra, Pradhyumna Kumar Singh & Srikanta Kumar Rath. (2015) Isoniazid prevents Nrf2 translocation by inhibiting ERK1 phosphorylation and induces oxidative stress and apoptosis. Redox Biology 6, pages 80-92.
Crossref
Sivaranjani Arivalagan, Nisha Susan Thomas, Balaji Chandrasekaran, Vijay Mani, Aktarul Islam Siddique, Thayalan Kuppsamy & Nalini Namasivayam. (2015) Combined therapeutic efficacy of carvacrol and X-radiation against 1,2-dimethyl hydrazine-induced experimental rat colon carcinogenesis. Molecular and Cellular Biochemistry 410:1-2, pages 37-54.
Crossref
Atieh Hajirahimkhan, Charlotte Simmler, Huali Dong, Daniel D. Lantvit, Guannan Li, Shao-Nong Chen, Dejan Nikolić, Guido F. Pauli, Richard B. van Breemen, Birgit M. Dietz & Judy L. Bolton. (2015) Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women’s Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A . Chemical Research in Toxicology 28:11, pages 2130-2141.
Crossref
Junsei Mimura & Ken Itoh. (2015) Role of Nrf2 in the pathogenesis of atherosclerosis. Free Radical Biology and Medicine 88, pages 221-232.
Crossref
Ranko Gacesa, Walter C. Dunlap & Paul F. Long. (2015) Bioinformatics analyses provide insight into distant homology of the Keap1–Nrf2 pathway. Free Radical Biology and Medicine 88, pages 373-380.
Crossref
Olivier Escaffre, Hailey Halliday, Viktoriya Borisevich, Antonella Casola & Barry Rockx. (2015) Oxidative stress in Nipah virus-infected human small airway epithelial cells. Journal of General Virology 96:10, pages 2961-2970.
Crossref
Neal S. Gould, Elysia Min, Jie Huang, Hong Wei Chu, Jim Good, Richard J. Martin & Brian J. Day. (2015) Glutathione Depletion Accelerates Cigarette Smoke-Induced Inflammation and Airspace Enlargement. Toxicological Sciences 147:2, pages 466-474.
Crossref
Hye‐Kyung Na & Young‐Joon Surh. 2015. Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods. Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods 102 121 .
Sooyeon Lim, Eun Jin Lee & Jongkee Kim. (2015) Decreased sulforaphene concentration and reduced myrosinase activity of radish (Raphanus sativus L.) root during cold storage. Postharvest Biology and Technology 100, pages 219-225.
Crossref
Hongming Lv, Hua Ren, Lidong Wang, Wei Chen & Xinxin Ci. (2015) Lico A Enhances Nrf2-Mediated Defense Mechanisms against t -BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells . Oxidative Medicine and Cellular Longevity 2015, pages 1-13.
Crossref
S. Mathan Kumar & Aparajita Dey. (2014) Regulation of Glutathione in Health and Disease with Special Emphasis on Chronic Alcoholism and Hyperglycaemia Mediated Liver Injury: A Brief Perspective. Springer Science Reviews 2:1-2, pages 1-13.
Crossref
C. Espinosa, F. Pérez-Llamas, F. A. Guardiola, M. A. Esteban, M. B. Arnao, S. Zamora & J. A. López-Jiménez. (2014) Molecular mechanisms by which white tea prevents oxidative stress. Journal of Physiology and Biochemistry 70:4, pages 891-900.
Crossref
Philip Hewitt & Esther Johann. 2014. Predictive Toxicology. Predictive Toxicology 73 96 .
Yongyong Hou, Yi Wang, Huihui Wang & Yuanyuan Xu. (2014) Induction of glutathione synthesis in human hepatocytes by acute and chronic arsenic exposure: Differential roles of mitogen-activated protein kinases. Toxicology 325, pages 96-106.
Crossref
Xiaoxu Duan, Dan Liu, Xiaoyue Xing, Jinlong Li, Shuo Zhao, Huifang Nie, Yang Zhang, Guifan Sun & Bing Li. (2014) Tert-Butylhydroquinone as a Phenolic Activator of Nrf2 Antagonizes Arsenic-Induced Oxidative Cytotoxicity but Promotes Arsenic Methylation and Detoxication in Human Hepatocyte Cell Line. Biological Trace Element Research 160:2, pages 294-302.
Crossref
Wylly Ramsés García-Niño & José Pedraza-Chaverrí. (2014) Protective effect of curcumin against heavy metals-induced liver damage. Food and Chemical Toxicology 69, pages 182-201.
Crossref
Khosrow Kashfi. (2014) Anti-Cancer Activity of New Designer Hydrogen Sulfide-Donating Hybrids. Antioxidants & Redox Signaling 20:5, pages 831-846.
Crossref
HUI ZHANG, ZENG-JUN GUO, WEN-MING XU, XIAO-JUAN YOU, LING HAN, YAN-XIA HAN & LIU-JIANG DAI. (2014) Antitumor effect and mechanism of an ellagic acid derivative on the HepG2 human hepatocellular carcinoma cell line. Oncology Letters 7:2, pages 525-530.
Crossref
Sanghyun Kim, Hee-Geum Lee, Sin-Aye Park, Joydeb Kumar Kundu, Young-Sam Keum, Young-Nam Cha, Hye-Kyung Na & Young-Joon Surh. (2014) Keap1 Cysteine 288 as a Potential Target for Diallyl Trisulfide-Induced Nrf2 Activation. PLoS ONE 9:1, pages e85984.
Crossref
Anabel Fernández-Iglesias, Helena Quesada, Sabina Díaz, David Pajuelo, Cinta Bladé, Lluís Arola, M. Josepa Salvadó & Miquel Mulero. (2013) DHA sensitizes FaO cells to tert-BHP-induced oxidative effects. Protective role of EGCG. Food and Chemical Toxicology 62, pages 750-757.
Crossref
Mohamed E. Abazeed, Drew J. Adams, Kristen E. Hurov, Pablo Tamayo, Chad J. Creighton, Dmitriy Sonkin, Andrew O. Giacomelli, Charles Du, Daniel F. Fries, Kwok-Kin Wong, Jill P. Mesirov, Jay S. Loeffler, Stuart L. Schreiber, Peter S. Hammerman & Matthew Meyerson. (2013) Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer. Cancer Research 73:20, pages 6289-6298.
Crossref
Ann M. BodeZigang Dong. (2013) Signal Transduction and Molecular Targets of Selected Flavonoids. Antioxidants & Redox Signaling 19:2, pages 163-180.
Crossref
Jung-Hwan KimEugenia Y. XuDavid B. SacksJonghun LeeLimin ShuBing XiaAh-Ng Tony Kong. (2013) Identification and Functional Studies of a New Nrf2 Partner IQGAP1: A Critical Role in the Stability and Transactivation of Nrf2. Antioxidants & Redox Signaling 19:2, pages 89-101.
Crossref
Candice E. Paulsen & Kate S. Carroll. (2013) Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery. Chemical Reviews 113:7, pages 4633-4679.
Crossref
Jae Ho Choi, Sun Woo Jin, Hyung Gyun Kim, Tilak Khanal, Yong Pil Hwang, Kyung Jin Lee, Chul Yung Choi, Young Chul Chung, Young Chun Lee & Hye Gwang Jeong. (2013) Platycodi Radix attenuates dimethylnitrosamine-induced liver fibrosis in rats by inducing Nrf2-mediated antioxidant enzymes. Food and Chemical Toxicology 56, pages 231-239.
Crossref
Seung Eun Lee & Yong Seek Park. (2013) The role of antioxidant enzymes in adaptive responses to environmental toxicants in vascular disease. Molecular & Cellular Toxicology 9:2, pages 95-101.
Crossref
Shan He, XuFang Liang, Dan Shen, WenBing Zhang & KangSen Mai. (2013) Effects of dietary tert-butylhydroquinone on domoic acid metabolism and transcription of detoxification-related liver genes in red sea bream Pagrus major. Chinese Science Bulletin 58:16, pages 1906-1911.
Crossref
Yuan-jing Fan, Yu Rong, Peng-fei Li, Wan-ling Dong, Dong-yin Zhang, Ling Zhang & Min-jie Cui. (2013) Genistein protection against acetaminophen-induced liver injury via its potential impact on the activation of UDP-glucuronosyltransferase and antioxidant enzymes. Food and Chemical Toxicology 55, pages 172-181.
Crossref
Shan He, Xu-Fang Liang, Jian Sun & Dan Shen. (2013) Induction of liver GST transcriptions by tert-butylhydroquinone reduced microcystin-LR accumulation in Nile tilapia (Oreochromis niloticus). Ecotoxicology and Environmental Safety 90, pages 128-135.
Crossref
Kyung-Mi Lee, Kyungsu Kang, Saet Byoul Lee & Chu Won Nho. (2013) Nuclear factor-E2 (Nrf2) is regulated through the differential activation of ERK1/2 and PKC ?/?II by Gymnasterkoreayne B. Cancer Letters 330:2, pages 225-232.
Crossref
Jong Hun Lee, Tin Oo Khor, Limin Shu, Zheng-Yuan Su, Francisco Fuentes & Ah-Ng Tony Kong. (2013) Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression. Pharmacology & Therapeutics 137:2, pages 153-171.
Crossref
Dona Sinha, Jaydip Biswas & Anupam Bishayee. (2012) Nrf2-mediated redox signaling in arsenic carcinogenesis: a review. Archives of Toxicology 87:2, pages 383-396.
Crossref
Xiaohan Zhai, Musen Lin, Feng Zhang, Yan Hu, Xiaomei Xu, Yubing Li, Kexin Liu, Xiaochi Ma, Xiaofeng Tian & Jihong Yao. (2012) Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco‐2 cells. Molecular Nutrition & Food Research 57:2, pages 249-259.
Crossref
J-H Kim, S Yu, J D Chen & A N Kong. (2012) The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains. Oncogene 32:4, pages 514-527.
Crossref
Biswa Nath Das, Young-Woo Kim & Young-Sam Keum. (2013) Mechanisms of Nrf2/Keap1-Dependent Phase II Cytoprotective and Detoxifying Gene Expression and Potential Cellular Targets of Chemopreventive Isothiocyanates. Oxidative Medicine and Cellular Longevity 2013, pages 1-7.
Crossref
Li Li, Ji-kun Du, Li-yi Zou, Tie Wu, Yong-woo Lee & Yong-ho Kim. (2013) Decursin Isolated from Angelica gigas Nakai Rescues PC12 Cells from Amyloid -Protein-Induced Neurotoxicity through Nrf2-Mediated Upregulation of Heme Oxygenase-1: Potential Roles of MAPK . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-14.
Crossref
Wenpeng Cui, Yang Bai, Ping Luo, Lining Miao & Lu Cai. (2013) Preventive and Therapeutic Effects of MG132 by Activating Nrf2-ARE Signaling Pathway on Oxidative Stress-Induced Cardiovascular and Renal Injury. Oxidative Medicine and Cellular Longevity 2013, pages 1-10.
Crossref
Amr Y. Esmat, Mahmoud M. Said, Amel A. Soliman, Khaled S.H. El-Masry & Elham Abdel Badiea. (2013) Bioactive compounds, antioxidant potential, and hepatoprotective activity of sea cucumber (Holothuria atra) against thioacetamide intoxication in rats. Nutrition 29:1, pages 258-267.
Crossref
Spyros K. Stamatelos, Ioannis P. Androulakis, Ah-Ng Tony Kong & Panos G. Georgopoulos. (2013) A semi-mechanistic integrated toxicokinetic–toxicodynamic (TK/TD) model for arsenic(III) in hepatocytes. Journal of Theoretical Biology 317, pages 244-256.
Crossref
Gonçalo Covas, H. Susana Marinho, Luísa Cyrne & Fernando Antunes. 2013. Hydrogen Peroxide and Cell Signaling, Part C. Hydrogen Peroxide and Cell Signaling, Part C 157 171 .
Sanjeev Banerjee & Paulraj Rajamani. 2013. Natural Products. Natural Products 2175 2254 .
Fang Hao, Neelu Yadav & Dhyan Chandra. 2013. Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy. Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy 219 243 .
Eliz Warwick, Aedín Cassidy, Bryan Hanley, Zeina E. Jouni & Yongping Bao. (2012) Effect of phytochemicals on phase II enzyme expression in infant human primary skin fibroblast cells. British Journal of Nutrition 108:12, pages 2158-2165.
Crossref
Fekadu Yadetie, Stephen Butcher, Hilde E Førde, Coen Campsteijn, Jean-Marie Bouquet, Odd A Karlsen, France Denoeud, Raghu Metpally, Eric M Thompson, J Robert Manak, Anders Goksøyr & Daniel Chourrout. (2012) Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics. BMC Genomics 13:1.
Crossref
Yoav Sharoni, Karin Linnewiel-Hermoni, Gabriel Zango, Marina Khanin, Hagar Salman, Anna Veprik, Michael Danilenko & Joseph Levy. (2012) The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention. The American Journal of Clinical Nutrition 96:5, pages 1173S-1178S.
Crossref
Keisuke Yaku, Yuka Enami, Chika Kurajyo, Isao Matsui-Yuasa, Yotaro Konishi & Akiko Kojima-Yuasa. (2012) The enhancement of phase 2 enzyme activities by sodium butyrate in normal intestinal epithelial cells is associated with Nrf2 and p53. Molecular and Cellular Biochemistry 370:1-2, pages 7-14.
Crossref
Bridgette M. Collins-Burow, James W. Antoon, Daniel E. Frigo, Steven Elliott, Christopher B. Weldon, Stephen M. Boue, Barbara S. Beckman, Tyler J. Curiel, Jawed Alam, John A. McLachlan & Matthew E. Burow. (2012) Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha. The Journal of Steroid Biochemistry and Molecular Biology 132:1-2, pages 186-193.
Crossref
Amlan Das, Bhavani Gopalakrishnan, Oliver H. Voss, Andrea I. Doseff & Frederick A. Villamena. (2012) Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling. Biochemical Pharmacology 84:4, pages 486-497.
Crossref
Haiyan Lou, Xu Jing, Dongmei Ren, Xinbing Wei & Xiumei Zhang. (2012) Eriodictyol protects against H2O2-induced neuron-like PC12 cell death through activation of Nrf2/ARE signaling pathway. Neurochemistry International 61:2, pages 251-257.
Crossref
Carlos Enrique Guerrero-Beltr?n, Mariel Calder?n-Oliver, Jos? Pedraza-Chaverri & Yolanda Irasema Chirino. (2012) Protective effect of sulforaphane against oxidative stress: Recent advances. Experimental and Toxicologic Pathology 64:5, pages 503-508.
Crossref
Natarajan Bhaskaran, Sanjeev Shukla, Rajnee Kanwal, Janmejai K. Srivastava & Sanjay Gupta. (2012) Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress. Life Sciences 90:25-26, pages 1027-1033.
Crossref
So-Young Joo, Young-A Song, Young-Lan Park, Eun Myung, Cho-Yun Chung, Kang-Jin Park, Sung-Bum Cho, Wan-Sik Lee, Hyun-Soo Kim, Jong-Sun Rew, Nack-Sung Kim & Young-Eun Joo. (2012) Epigallocatechin-3-gallate Inhibits LPS-Induced NF-κB and MAPK Signaling Pathways in Bone Marrow-Derived Macrophages. Gut and Liver 6:2, pages 188-196.
Crossref
Carmela Fimognari, Eleonora Turrini, Lorenzo Ferruzzi, Monia Lenzi & Patrizia Hrelia. (2012) Natural isothiocyanates: Genotoxic potential versus chemoprevention. Mutation Research/Reviews in Mutation Research 750:2, pages 107-131.
Crossref
Takuji Tanaka, Masahito Shnimizu & Hisataka Moriwaki. (2012) Cancer Chemoprevention by Carotenoids. Molecules 17:3, pages 3202-3242.
Crossref
Marlies Van de Wouwer, C?lia Couzini?Miguel Serrano-Palero, ?scar Gonz?lez-Fern?ndez, Clara Galm?s-Varela, Paula Men?ndez-Antol?Laura Grau & Antonio Villalobo. (2012) Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells. Nitric Oxide 26:3, pages 182-191.
Crossref
Changhan Lee, Lizzia Raffaghello & Valter D. Longo. (2012) Starvation, detoxification, and multidrug resistance in cancer therapy. Drug Resistance Updates 15:1-2, pages 114-122.
Crossref
Pinar E. Coskun & Jorge Busciglio. (2012) Oxidative Stress and Mitochondrial Dysfunction in Down’s Syndrome: Relevance to Aging and Dementia. Current Gerontology and Geriatrics Research 2012, pages 1-7.
Crossref
Michela Festa, Anna Capasso, Cosimo W. D’Acunto, Milena Masullo, Adriano G. RossiCosimo Pizza & Sonia Piacente. (2011) Xanthohumol Induces Apoptosis in Human Malignant Glioblastoma Cells by Increasing Reactive Oxygen Species and Activating MAPK Pathways. Journal of Natural Products 74:12, pages 2505-2513.
Crossref
Ya-Chen Yang, Chong-Kuei Lii, Ai-Hsuan Lin, Yu-Wen Yeh, Hsien-Tsung Yao, Chien-Chun Li, Kai-Li Liu & Haw-Wen Chen. (2011) Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress. Free Radical Biology and Medicine 51:11, pages 2073-2081.
Crossref
Yong Pil Hwang, Jae Ho Choi, Jun Min Choi, Young Chul Chung & Hye Gwang Jeong. (2011) Protective mechanisms of anthocyanins from purple sweet potato against tert-butyl hydroperoxide-induced hepatotoxicity. Food and Chemical Toxicology 49:9, pages 2081-2089.
Crossref
Kyoung-jin Min, Jung Tae Lee, Eun-hye Joe & Taeg Kyu Kwon. (2011) An I?B? phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)?Nrf2?ARE signaling and ROS?PI3K/Akt signaling in an NF-?B-independent mechanism. Cellular Signalling 23:9, pages 1505-1513.
Crossref
Sonia Messina, Alessandra Bitto, M’hammed Aguennouz, Gian Luca Vita, Francesca Polito, Natasha Irrera, Domenica Altavilla, Herbert Marini, Alba Migliorato, Francesco Squadrito & Giuseppe Vita. (2011) The soy isoflavone genistein blunts nuclear factor kappa-B, MAPKs and TNF-α activation and ameliorates muscle function and morphology in mdx mice. Neuromuscular Disorders 21:8, pages 579-589.
Crossref
John W. Finley, Ah-Ng Kong, Korry J. Hintze, Elizabeth H. Jeffery, Li Li Ji & Xin Gen Lei. (2011) Antioxidants in Foods: State of the Science Important to the Food Industry. Journal of Agricultural and Food Chemistry 59:13, pages 6837-6846.
Crossref
Violetta Krajka-Kuźniak, Hanna Szaefer, Agnieszka Bartoszek & Wanda Baer-Dubowska. (2010) Modulation of rat hepatic and kidney phase II enzymes by cabbage juices: comparison with the effects of indole-3-carbinol and phenethyl isothiocyanate. British Journal of Nutrition 105:6, pages 816-826.
Crossref
Christophe Butticaz, René Gysin, Michel Cuénod & Kim Q. Do. (2011) Interaction of GAG trinucleotide repeat and C−129T polymorphisms impairs expression of the glutamate–cysteine ligase catalytic subunit gene. Free Radical Biology and Medicine 50:5, pages 617-623.
Crossref
Priya Sathish, Vijayalakshmi Paramasivan, Vivekanandan Palani & Karthikeyan Sivanesan. (2011) N-acetylcysteine attenuates dimethylnitrosamine induced oxidative stress in rats. European Journal of Pharmacology 654:2, pages 181-186.
Crossref
Arnulfo Quesada, Julie Ogi, James Schultz & Adrian Handforth. (2011) C-terminal mechano-growth factor induces heme oxygenase-1-mediated neuroprotection of SH-SY5Y cells via the protein kinase C?/Nrf2 pathway. Journal of Neuroscience Research 89:3, pages 394-405.
Crossref
Collin L. Ellis, Indika Edirisinghe, Tissa Kappagoda & Britt Burton-Freeman. (2011) Attenuation of Meal-Induced Inflammatory and Thrombotic Responses in Overweight Men and Women After 6-Week Daily Strawberry (Fragaria) Intake. Journal of Atherosclerosis and Thrombosis 18:4, pages 318-327.
Crossref
Seewan KimYoung-Eun Joo. (2011) Theaflavin Inhibits LPS-Induced IL-6, MCP-1, and ICAM-1 Expression in Bone Marrow-Derived Macrophages Through the Blockade of NF-κB and MAPK Signaling Pathways. Chonnam Medical Journal 47:2, pages 104.
Crossref
Young Jin Moon, Daniel A. Brazeau & Marilyn E. Morris. (2011) Dietary Phenethyl Isothiocyanate Alters Gene Expression in Human Breast Cancer Cells. Evidence-Based Complementary and Alternative Medicine 2011, pages 1-8.
Crossref
Min-Hsiung Pan, Yi-Siou Chiou, Yin-Jen Wang, Chi-Tang Ho & Jen-Kun Lin. (2011) Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate. Food & Function 2:2, pages 101.
Crossref
Joseph Levy, Shlomo Walfisch, Andrea Atzmon, Keren Hirsch, Marina Khanin, Karin Linnewiel, Yael Morag, Hagar Salman, Anna Veprik, Michael Danilenko & Yoav Sharoni. 2011. Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention. Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention 47 66 .
Nobunao WakabayashiStephen L. SlocumJohn J. SkokoSoona ShinThomas W. Kensler. (2010) When NRF2 Talks, Who's Listening?. Antioxidants & Redox Signaling 13:11, pages 1649-1663.
Crossref
Ai-Lin Yu, Chia-Yang Lu, Tsu-Shing Wang, Chia-Wen Tsai, Kai-Li Liu, Yi-Ping Cheng, Hebron C. Chang, Chong-Kuei Lii & Haw-Wen Chen. (2010) Induction of Heme Oxygenase 1 and Inhibition of Tumor Necrosis Factor α-Induced Intercellular Adhesion Molecule Expression by Andrographolide in EA.hy926 Cells. Journal of Agricultural and Food Chemistry 58:13, pages 7641-7648.
Crossref
João Laranjinha. 2010. Recent Advances in Polyphenol Research. Recent Advances in Polyphenol Research 269 282 .
Ki Mo Kim, Dong Ho Jung, Dae Sik Jang, Young Sook Kim, Jong Min Kim, Ha-Na Kim, Young-Joon Surh & Jin Sook Kim. (2010) Puerarin suppresses AGEs-induced inflammation in mouse mesangial cells: A possible pathway through the induction of heme oxygenase-1 expression. Toxicology and Applied Pharmacology 244:2, pages 106-113.
Crossref
Ka Lung Cheung & Ah-Ng Kong. (2009) Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention. The AAPS Journal 12:1, pages 87-97.
Crossref
Anna Trzeciakiewicz, Veronique Habauzit, Sylvie Mercier, Denis Barron, Mireia Urpi-Sarda, Claudine Manach, Elizabeth Offord & Marie-Noelle Horcajada. (2009) Molecular Mechanism of Hesperetin-7- O -glucuronide, the Main Circulating Metabolite of Hesperidin, Involved in Osteoblast Differentiation . Journal of Agricultural and Food Chemistry 58:1, pages 668-675.
Crossref
Alberto Izzotti, George A. Calin, Vernon E. Steele, Cristina Cartiglia, Mariagrazia Longobardi, Carlo M. Croce & Silvio De Flora. (2010) Chemoprevention of Cigarette Smoke–Induced Alterations of MicroRNA Expression in Rat Lungs. Cancer Prevention Research 3:1, pages 62-72.
Crossref
Zhi Hong Wang, Kyoung Ah Kang, Rui Zhang, Mei Jing Piao, Su Hyun Jo, Ju Sun Kim, Sam Sik Kang, Jong Sung Lee, Deok Hoon Park & Jin Won Hyun. (2010) Myricetin suppresses oxidative stress-induced cell damage via both direct and indirect antioxidant action. Environmental Toxicology and Pharmacology 29:1, pages 12-18.
Crossref
David B. Peden. 2010. Asthma, Health and Society. Asthma, Health and Society 43 57 .
Alma E. Robles‐Sardin, Adriana Verónica Bolaños‐Villar, Gustavo A. González‐Aguilar & Laura A. de la Rosa. 2009. Fruit and Vegetable Phytochemicals. Fruit and Vegetable Phytochemicals 155 175 .
Siwang Yu, Ka Lung Cheung, Wenge Li & Ah‐Ng Kong. 2009. Plant Phenolics and Human Health. Plant Phenolics and Human Health 401 426 .
Saura C. Sahu. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Maria Elena Rodríguez-García, Adoración G. Quiroga, José Castro, Alberto Ortiz, Patricio Aller & Felicísima Mata. (2009) Inhibition of p38-MAPK Potentiates Cisplatin-Induced Apoptosis via GSH Depletion and Increases Intracellular Drug Accumulation in Growth-Arrested Kidney Tubular Epithelial Cells. Toxicological Sciences 111:2, pages 413-423.
Crossref
Yong Pil Hwang, Hyo Jeong Yun, Hyo Kon Chun, Young Chul Chung, Hyung Keun Kim, Myung Ho Jeong, Taek Rim Yoon & Hye Gwang Jeong. (2009) Protective mechanisms of 3-caffeoyl, 4-dihydrocaffeoyl quinic acid from Salicornia herbacea against tert-butyl hydroperoxide-induced oxidative damage. Chemico-Biological Interactions 181:3, pages 366-376.
Crossref
Guoxiang Shen & Ah‐Ng Kong. (2009) Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters. Biopharmaceutics & Drug Disposition 30:7, pages 345-355.
Crossref
Seung-Jin Lee, Gyeong-In Mun, Sang-Mi An & Yong-Chool Boo. (2009) Evidence for the association of peroxidases with the antioxidant effect of p-coumaric acid in endothelial cells exposed to high glucose plus arachidonic acid. BMB Reports 42:9, pages 561-567.
Crossref
Tanja K. RudolphBruce A. Freeman. (2009) Transduction of Redox Signaling by Electrophile-Protein Reactions. Science Signaling 2:90.
Crossref
Xiang-Lin Tan & Simon D. Spivack. (2009) Dietary chemoprevention strategies for induction of phase II xenobiotic-metabolizing enzymes in lung carcinogenesis: A review. Lung Cancer 65:2, pages 129-137.
Crossref
Fredine T. Lauer, Leah A. Mitchell, Edward Bedrick, Jacob D. McDonald, Wen-Yee Lee, Wen-Whai Li, Hector Olvera, Maria A. Amaya, Marianne Berwick, Melissa Gonzales, Robert Currey, Nicholas E. PingitoreJrJr & Scott W. Burchiel. (2009) Temporal–spatial analysis of U.S.–Mexico border environmental fine and coarse PM air sample extract activity in human bronchial epithelial cells. Toxicology and Applied Pharmacology 238:1, pages 1-10.
Crossref
Ariel F. Gualtieri, Graciela L. Mazzone, Rodolfo A. Rey & Helena F. Schteingart. (2009) FSH and bFGF stimulate the production of glutathione in cultured rat Sertoli cells. International Journal of Andrology 32:3, pages 218-225.
Crossref
Ruth L. T. Matsumoto, Deborah H. M. Bastos, Simone Mendonça, Valéria S. Nunes, Waldemar BartchewskyJr.Jr., Marcelo L. Ribeiro & Patrícia de Oliveira Carvalho. (2009) Effects of Maté Tea ( Ilex paraguariensis ) Ingestion on mRNA Expression of Antioxidant Enzymes, Lipid Peroxidation, and Total Antioxidant Status in Healthy Young Women . Journal of Agricultural and Food Chemistry 57:5, pages 1775-1780.
Crossref
Mi Kyung Kim & Jung Han Yoon Park. (2008) Cruciferous vegetable intake and the risk of human cancer: epidemiological evidence. Proceedings of the Nutrition Society 68:1, pages 103-110.
Crossref
Henry Jay Forman, Hongqiao Zhang & Alessandra Rinna. (2009) Glutathione: Overview of its protective roles, measurement, and biosynthesis. Molecular Aspects of Medicine 30:1-2, pages 1-12.
Crossref
Chi-Tai Yeh & Gow-Chin Yen. (2009) Chemopreventive functions of sulforaphane: A potent inducer of antioxidant enzymes and apoptosis. Journal of Functional Foods 1:1, pages 23-32.
Crossref
David B. Peden. 2009. Middleton's Allergy: Principles and Practice. Middleton's Allergy: Principles and Practice 495 508 .
Paola Palozza, Simona Serini, Maria Ameruso & Sara Verdecchia. 2009. Carotenoids. Carotenoids 211 234 .
Yong Pil Hwang & Hye Gwang Jeong. (2008) Mechanism of phytoestrogen puerarin-mediated cytoprotection following oxidative injury: Estrogen receptor-dependent up-regulation of PI3K/Akt and HO-1. Toxicology and Applied Pharmacology 233:3, pages 371-381.
Crossref
Jaime L. Rudolf, Kathryn A. Bauerly, Eskouhie Tchaparian, Robert B. Rucker & Alyson E. Mitchell. (2008) The influence of diet composition on phase I and II biotransformation enzyme induction. Archives of Toxicology 82:12, pages 893-901.
Crossref
Yong Pil Hwang, Jae Ho Choi, Eun Hee Han, Hyung Kyun Kim, Shin Keon Kang, Young Chul Chung & Hye Gwang Jeong. (2008) Protective mechanisms of Aralia continentalis extract against tert-butyl hydroperoxide-induced hepatotoxicity: In vivo and in vitro studies. Food and Chemical Toxicology 46:11, pages 3512-3521.
Crossref
Yanling Lin, Abby C. Collier, Wanyu Liu, Marla J. Berry & Jun Panee. (2008) The inhibitory effect of bamboo extract on the development of 7,12‐dimethylbenz[a]anthracene (DMBA)‐induced breast cancer. Phytotherapy Research 22:11, pages 1440-1445.
Crossref
Joydeb Kumar Kundu & Young-Joon Surh. (2008) Cancer chemopreventive and therapeutic potential of resveratrol: Mechanistic perspectives. Cancer Letters 269:2, pages 243-261.
Crossref
Joydeb Kumar Kundu, Hye-Kyung Na & Young-Joon Surh. 2008. Dietary Modulation of Cell Signaling Pathways. Dietary Modulation of Cell Signaling Pathways.
Yong Pil Hwang & Hye Gwang Jeong. (2008) The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress. FEBS Letters 582:17, pages 2655-2662.
Crossref
Rachana Patel & Girish Maru. (2008) Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs. Free Radical Biology and Medicine 44:11, pages 1897-1911.
Crossref
Gleeson MurphyJr.Jr., Rodney L. Rouse, William W. Polk, William G. Henk, Steven A. Barker, Marc J. Boudreaux, Z. Elizabeth Floyd & Arthur L. Penn. (2008) Combustion-Derived Hydrocarbons Localize to Lipid Droplets in Respiratory Cells. American Journal of Respiratory Cell and Molecular Biology 38:5, pages 532-540.
Crossref
Siegfried Knasmüller, Armen Nersesyan, Miroslav Mišík, Christopher Gerner, Wolfgang Mikulits, Veronika Ehrlich, Christine Hoelzl, Akos Szakmary & Karl-Heinz Wagner. (2008) Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview. British Journal of Nutrition 99:E-S1, pages ES3-ES52.
Crossref
Yong Pil Hwang, Eun Hee Han, Jae Ho Choi, Hyung Gyun Kim, Kyung Jin Lee, Tae Cheon Jeong, Eung Seok Lee & Hye Gwang Jeong. (2008) Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity. Toxicology and Applied Pharmacology 228:3, pages 343-350.
Crossref
Tao Wang, Ning-Ling Sun, Wei-Dong Zhang, Hui-Liang Li, Guo-Cai Lu, Bo-Jun Yuan, Hua Jiang, Jia-Hong She & Chuan Zhang. (2008) Protective effects of dehydrocavidine on carbon tetrachloride-induced acute hepatotoxicity in rats. Journal of Ethnopharmacology 117:2, pages 300-308.
Crossref
Hye-Kyung Na & Young-Joon Surh. (2008) Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. Food and Chemical Toxicology 46:4, pages 1271-1278.
Crossref
Defeng Wu & Arthur Cederbaum. (2008) Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice. Hepatology 47:3, pages 1005-1017.
Crossref
Richard Di Giulio & Joel Meyer. 2008. The Toxicology of Fishes. The Toxicology of Fishes 273 324 .
Laurent Marrot, Christophe Jones, Philippe Perez & Jean-Roch Meunier. (2007) ORIGINAL ARTICLE: The significance of Nrf2 pathway in (photo)-oxidative stress response in melanocytes and keratinocytes of the human epidermis. Pigment Cell & Melanoma Research 21:1, pages 79-88.
Crossref
Claudio Giovannini, Beatrice Scazzocchio, Paola Matarrese, Rosaria Varì, Massimo D'Archivio, Roberta Di Benedetto, Stefania Casciani, Maria Rita Dessì, Elisabetta Straface, Walter Malorni & Roberta Masella. (2008) Apoptosis induced by oxidized lipids is associated with up-regulation of p66Shc in intestinal Caco-2 cells: protective effects of phenolic compounds. The Journal of Nutritional Biochemistry 19:2, pages 118-128.
Crossref
Laura E. Randle, Chris E.P. Goldring, Craig A. Benson, Peter N. Metcalfe, Neil R. Kitteringham, B. Kevin Park & Dominic P. Williams. (2008) Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice. Toxicology 243:3, pages 249-260.
Crossref
G. Filomeni, I. Graziani, G. Rotilio & M. R. Ciriolo. (2007) trans-Resveratrol induces apoptosis in human breast cancer cells MCF-7 by the activation of MAP kinases pathways. Genes & Nutrition 2:3, pages 295-305.
Crossref
Jorge H. Limón-Pacheco, Norma A. Hernández, María L. Fanjul-Moles & María E. Gonsebatt. (2007) Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice. Free Radical Biology and Medicine 43:9, pages 1335-1347.
Crossref
Ying Hu, Sabine Urig, Sasa Koncarevic, Xinjiang Wu, Marina Fischer, Stefan Rahlfs, Volker Mersch-Sundermann & Katja Becker. (2007) Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents. bchm 388:10, pages 1069-1081.
Crossref
Soo-Yeon Park, Xiaofei Yu, Clement Ip, James L. Mohler, Paul N. Bogner & Young-Mee Park. (2007) Peroxiredoxin 1 Interacts with Androgen Receptor and Enhances Its Transactivation. Cancer Research 67:19, pages 9294-9303.
Crossref
Sally E. Purdom-Dickinson, Elena V. Sheveleva, Haipeng Sun & Qin M. Chen. (2007) Translational Control of Nrf2 Protein in Activation of Antioxidant Response by Oxidants. Molecular Pharmacology 72:4, pages 1074-1081.
Crossref
Guohao DaiSaran VaughnYuzhi ZhangEric T. WangGuillermo Garcia-CardenaMichael A. GimbroneJrJr. (2007) Biomechanical Forces in Atherosclerosis-Resistant Vascular Regions Regulate Endothelial Redox Balance via Phosphoinositol 3-Kinase/Akt-Dependent Activation of Nrf2. Circulation Research 101:7, pages 723-733.
Crossref
Mei-Hua Li, Jung-Hee Jang, Hye-Kyung Na, Young-Nam Cha & Young-Joon Surh. (2007) Carbon Monoxide Produced by Heme Oxygenase-1 in Response to Nitrosative Stress Induces Expression of Glutamate-Cysteine Ligase in PC12 Cells via Activation of Phosphatidylinositol 3-Kinase and Nrf2 Signaling. Journal of Biological Chemistry 282:39, pages 28577-28586.
Crossref
Jameel Ahmad Khan, Beena Pillai, Taposh Kumar Das, Yogendra Singh & Souvik Maiti. (2007) Molecular Effects of Uptake of Gold Nanoparticles in HeLa Cells. ChemBioChem 8:11, pages 1237-1240.
Crossref
David P. Tomer, Lee D. McLeman, Seiga Ohmine, Philip M. Scherer, Byron K. Murray & Kim L. O'Neill. (2007) Comparison of the Total Oxyradical Scavenging Capacity and Oxygen Radical Absorbance Capacity Antioxidant Assays. Journal of Medicinal Food 10:2, pages 337-344.
Crossref
Carmela Fimognari & Patrizia Hrelia. (2007) Sulforaphane as a promising molecule for fighting cancer. Mutation Research/Reviews in Mutation Research 635:2-3, pages 90-104.
Crossref
Yun-Jeong Kim, Ji-Yeon Ahn, Ping Liang, Clement Ip, Yuesheng Zhang & Young-Mee Park. (2007) Human prx1 Gene Is a Target of Nrf2 and Is Up-regulated by Hypoxia/Reoxygenation: Implication to Tumor Biology . Cancer Research 67:2, pages 546-554.
Crossref
Ming Zhu, Yuesheng Zhang & G. Tim Bowden. (2006) Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes. Cancer Letters 244:2, pages 220-228.
Crossref
Irfan Rahman. (2006) Beneficial effects of dietary polyphenols using lung inflammation as a model. Journal of the Science of Food and Agriculture 86:15, pages 2499-2502.
Crossref

Displaying 200 of 263 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.