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M. Khalil Ramla, B. M. Goffredo, F. Giustini, M. Pisani, S. Cairoli, R. Simeoli, J. Nunziata, S. Perdichizzi, I. Savarese & M. Marano. (2022) The importance of free digoxin serum levels after digoxin poisoning. Clinical Toxicology 60:1, pages 136-137.
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Zalina Zahari, Chee Siong Lee, Muslih Abdulkarim Ibrahim, Nurfadhlina Musa, Mohd Azhar Mohd Yasin, Yeong Yeh Lee, Soo Choon Tan, Nasir Mohamad & Rusli Ismail. (2016) Relationship between polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT). The American Journal of Drug and Alcohol Abuse 42:5, pages 587-596.
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Weiming Ding, Xucheng Hou, Shuangchen Cong, Yuanyuan Zhang, Mengmeng Chen, Jiongxi Lei, Yansha Meng, Xinru Li & Guiling Li. (2016) Co-delivery of honokiol, a constituent of Magnolia species, in a self-microemulsifying drug delivery system for improved oral transport of lipophilic sirolimus. Drug Delivery 23:7, pages 2513-2523.
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Jian-Wei Chen, Qi-Hao Wu, David C. Rowley, Ammar M.Q. Al-Kareef & Hong Wang. (2015) Anticancer agent-based marine natural products and related compounds. Journal of Asian Natural Products Research 17:2, pages 199-216.
Read now
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Daniel T Barratt, Janet K Coller, Richard Hallinan, Andrew Byrne, Jason M White, David JR Foster & Andrew A Somogyi. (2012) ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics. Pharmacogenomics and Personalized Medicine 5, pages 53-62.
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Bianca M. Liederer, Leonid M. Berezhkovskiy, Brian J. Dean, Vikki Dinkel, Jing Peng, Mark Merchant, Emile G. Plise, Harvey Wong & Xingrong Liu. (2011) Preclinical absorption, distribution, metabolism, excretion, and pharmacokinetic–pharmacodynamic modelling of N-(4-(3-((3S,4R)-1-ethyl-3-fluoropiperidine-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide, a novel MET kinase inhibitor. Xenobiotica 41:4, pages 327-339.
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J.-S. Taur & R. Rodriguez-Proteau. (2008) Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models. Xenobiotica 38:12, pages 1536-1550.
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H. Lennernäs. (2007) Intestinal permeability and its relevance for absorption and elimination. Xenobiotica 37:10-11, pages 1015-1051.
Read now
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Jiunn H Lin. (2007) Transporter-mediated drug interactions: clinical implications and in vitro assessment. Expert Opinion on Drug Metabolism & Toxicology 3:1, pages 81-92.
Read now
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George L Trainor. (2007) The importance of plasma protein binding in drug discovery. Expert Opinion on Drug Discovery 2:1, pages 51-64.
Read now
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François Girardin. (2006) Membrane transporter proteins: a challenge for CNS drug development. Dialogues in Clinical Neuroscience 8:3, pages 311-321.
Read now
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Keith W Ward. (2005) Recent advances in pharmacokinetic extrapolation from preclinical data to humans. Expert Opinion on Drug Metabolism & Toxicology 1:4, pages 583-594.
Read now
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Takaharu Mizutani & Asuka Hattori. (2005) New Horizon of MDR1 (P-glycoprotein) Study. Drug Metabolism Reviews 37:3, pages 489-510.
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Articles from other publishers (127)
Seung-Hyun Jeong, Ji-Hun Jang & Yong-Bok Lee. (2023) P-glycoprotein mechanical functional analysis using in silico molecular modeling: Pharmacokinetic variability according to ABCB1 c.2677G > T/A genetic polymorphisms. International Journal of Biological Macromolecules 249, pages 126777.
Crossref
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Norma Flores-Holguín, Juan Frau & Daniel Glossman-Mitnik. (2023) Exploring the potential and limitations of cyclopeptides as pharmaceutical drugs: a computational peptidology approach to the study of grassypeptolides A-G. Theoretical Chemistry Accounts 142:9.
Crossref
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Yajuan Bi, Xue Wang, Hui Ding, Feng He, Lifeng Han & Youcai Zhang. (2022) Transporter-mediated Natural Product-Drug Interactions. Planta Medica 89:02, pages 119-133.
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Defei Qi, Yuanyuan Dou, Wenke Zhang, Mengqing Wang, Yingying Li, Mingzhu Zhang, Jia Qin, Jinlan Cao, Dong Fang, Jing Ma, Wei Yang, Songqiang Xie & Hua Sun. (2022) The influence of verapamil on the pharmacokinetics of the pan-HER tyrosine kinase inhibitor neratinib in rats: the role of P-glycoprotein-mediated efflux. Investigational New Drugs 41:1, pages 13-24.
Crossref
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Upendra P. Dahal & Jan L. Wahlstrom. 2023. Overcoming Obstacles in Drug Discovery and Development. Overcoming Obstacles in Drug Discovery and Development
51
62
.
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967
992
.
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Sai Sriram, Yusuf Mehkri, Stephan Quintin & Brandon Lucke-Wold. (2022) Shared pathophysiology: Understanding stroke and Alzheimer’s disease. Clinical Neurology and Neurosurgery 218, pages 107306.
Crossref
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Nidhi Saini, Ajmer Singh Grewal, Viney Lather & Suresh Kumar Gahlawat. (2022) Natural alkaloids targeting EGFR in non-small cell lung cancer: Molecular docking and ADMET predictions. Chemico-Biological Interactions 358, pages 109901.
Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Sailaja KamarajuMeera MohanSvetlana ZaharovaBrianna WallaceJoseph McGrawJames LokkenJohn TierneyElizabeth WeilOlubadewa FatundeSherry-Ann Brown. (2021) Interactions between cardiology and oncology drugs in precision cardio-oncology. Clinical Science 135:11, pages 1333-1351.
Crossref
Crossref
Donglu Zhang, Cong WeiCornelis E. C. A. HopMatthew R. WrightMing HuYurong Lai, S. Cyrus KhojastehW. Griff Humphreys. (2021) Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs. Journal of Medicinal Chemistry 64:11, pages 7045-7059.
Crossref
Crossref
Mahmoud Zaki El-Readi, Ahmed M. Al-Abd, Mohammad A. Althubiti, Riyad A. Almaimani, Hiba Saeed Al-Amoodi, Mohamed Lotfy Ashour, Michael Wink & Safaa Yehia Eid. (2021) Multiple Molecular Mechanisms to Overcome Multidrug Resistance in Cancer by Natural Secondary Metabolites. Frontiers in Pharmacology 12.
Crossref
Crossref
Zuxiong Tang, Jun He, Jiayue Zou, Shufei Yu, Xiaoming Sun & Lei Qin. (2021) Cisplatin-resistant HepG2 cell-derived exosomes transfer cisplatin resistance to cisplatin-sensitive cells in HCC. PeerJ 9, pages e11200.
Crossref
Crossref
Alejandra Martínez-Chávez, Jelle Broeders, Maria C. Lebre, Matthijs T. Tibben, Hilde Rosing, Jos H. Beijnen & Alfred H. Schinkel. (2021) The role of drug efflux and uptake transporters ABCB1 (P-gp), ABCG2 (BCRP) and OATP1A/1B and of CYP3A4 in the pharmacokinetics of the CDK inhibitor milciclib. European Journal of Pharmaceutical Sciences 159, pages 105740.
Crossref
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Nitika Garg, Rupa Joshi & Bikash Medhi. (2020) A novel approach of targeting refractory epilepsy: Need of an hour. Brain Research Bulletin 163, pages 14-20.
Crossref
Crossref
Elizabeth Varghese, Samson Mathews Samuel, Alena Líšková, Marek Samec, Peter Kubatka & Dietrich Büsselberg. (2020) Targeting Glucose Metabolism to Overcome Resistance to Anticancer Chemotherapy in Breast Cancer. Cancers 12:8, pages 2252.
Crossref
Crossref
Akshay S. Parchure & Yuan B. Peng. (2020) The Impact of Opioid Analgesics and the Pharmacogenomics of ABCB1 in Opioid Dependence and Pharmacotherapies: A Short Review. The Open Pain Journal 13:1, pages 7-21.
Crossref
Crossref
Chun Chen, Hongyu Zhou, Chi Guan, Huanhuan Zhang, Yingying Li, Xue Jiang, Zheng Dong, Yuanyuan Tao, Juan Du, Shuyao Wang, Teng Zhang, Na Du, Junyang Guo, Yaqiong Wu, Zehai Song, Haofei Luan, Yu Wang, Hongwen Du, Shaofeng Zhang, Chen Li, Hang Chang & Tao Wang. (2020) Applicability of free drug hypothesis to drugs with good membrane permeability that are not efflux transporter substrates: A microdialysis study in rats. Pharmacology Research & Perspectives 8:2.
Crossref
Crossref
Taiji Miyake. (2020) Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats. Biological and Pharmaceutical Bulletin 43:3, pages 384-392.
Crossref
Crossref
Clément Mercier, Elodie Jacqueroux, Zhiguo He, Sophie Hodin, Samuel Constant, Nathalie Perek, Delphine Boudard & Xavier Delavenne. (2019) Pharmacological characterization of the 3D MucilAir™ nasal model. European Journal of Pharmaceutics and Biopharmaceutics 139, pages 186-196.
Crossref
Crossref
Dianlei Wang. 2019. Drug Transporters in Drug Disposition, Effects and Toxicity. Drug Transporters in Drug Disposition, Effects and Toxicity
203
240
.
Xiaodong Liu. 2019. Drug Transporters in Drug Disposition, Effects and Toxicity. Drug Transporters in Drug Disposition, Effects and Toxicity
13
100
.
Liu Dou, Yang Mai, Christine M. Madla, Mine Orlu & Abdul W. Basit. (2018) P-glycoprotein expression in the gastrointestinal tract of male and female rats is influenced differently by food. European Journal of Pharmaceutical Sciences 123, pages 569-575.
Crossref
Crossref
Avital Beig, Milica Markovic & Arik Dahan. 2018. Early Drug Development. Early Drug Development
171
202
.
Anthony J. Roecker, Melissa Egbertson, Kristen L.G. Jones, Robert Gomez, Richard L. Kraus, Yuxing Li, Amy Jo Koser, Mark O. Urban, Rebecca Klein, Michelle Clements, Jacqueline Panigel, Christopher Daley, Jixin Wang, Eleftheria N. Finger, John Majercak, Vincent Santarelli, Irene Gregan, Matthew Cato, Tracey Filzen, Aneta Jovanovska, Ying-Hong Wang, Deping Wang, Leo A. Joyce, Edward C. Sherer, Xuanjia Peng, Xiu Wang, Haiyan Sun, Paul J. Coleman, Andrea K. Houghton & Mark E. Layton. (2017) Discovery of selective, orally bioavailable, N -linked arylsulfonamide Na v 1.7 inhibitors with pain efficacy in mice. Bioorganic & Medicinal Chemistry Letters 27:10, pages 2087-2093.
Crossref
Crossref
Kayoko Ohura, Hikaru Nishiyama, Saori Saco, Keisuke Kurokawa & Teruko Imai. (2016) Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine. Drug Metabolism and Disposition 44:12, pages 1890-1898.
Crossref
Crossref
D Zhou, K Bui, M Sostek & N Al‐Huniti. (2016) Simulation and Prediction of the Drug‐Drug Interaction Potential of Naloxegol by Physiologically Based Pharmacokinetic Modeling. CPT: Pharmacometrics & Systems Pharmacology 5:5, pages 250-257.
Crossref
Crossref
Armin Bauer. 2016. Synthesis of Heterocycles in Contemporary Medicinal Chemistry. Synthesis of Heterocycles in Contemporary Medicinal Chemistry
209
270
.
Rui Peng, Hong Zhang, Ying Zhang & Dan-Yun Wei. (2015) Effects of the ABCB1 (1199G > A) Polymorphism on Steroid Sex Hormone-Induced P-Glycoprotein Expression, ATPase Activity, and Hormone Efflux. Medical Sciences 3:4, pages 124-137.
Crossref
Crossref
Anthony J. Roecker, Swati P. Mercer, Jeffrey M. Bergman, Kevin F. Gilbert, Scott D. Kuduk, C. Meacham Harrell, Susan L. Garson, Steven V. Fox, Anthony L. Gotter, Pamela L. Tannenbaum, Thomayant Prueksaritanont, Tamara D. Cabalu, Donghui Cui, Wei Lemaire, Christopher J. Winrow, John J. Renger & Paul J. Coleman. (2015) Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacements. Bioorganic & Medicinal Chemistry Letters 25:21, pages 4992-4999.
Crossref
Crossref
S. E. Lacher, K. Skagen, J. Veit, R. Dalton & E. L. Woodahl. (2015) P-Glycoprotein Transport of Neurotoxic Pesticides. Journal of Pharmacology and Experimental Therapeutics 355:1, pages 99-107.
Crossref
Crossref
Renata Silva, Vânia Vilas-Boas, Helena Carmo, Ricardo Jorge Dinis-Oliveira, Félix Carvalho, Maria de Lourdes Bastos & Fernando Remião. (2015) Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy. Pharmacology & Therapeutics 149, pages 1-123.
Crossref
Crossref
Daigo Hayashi, Naoki Tsukioka, Yutaka Inoue, Yoshiki Matsubayashi, Toshimasa Iizuka, Kazuhiro Higuchi, Yoji Ikegami & Tomomi Kawasaki. (2015) Synthesis and ABCG2 inhibitory evaluation of 5-N-acetylardeemin derivatives. Bioorganic & Medicinal Chemistry 23:9, pages 2010-2023.
Crossref
Crossref
Bhanudas Dasari, Ravikumar Jimmidi & Prabhat Arya. (2015) Selected hybrid natural products as tubulin modulators. European Journal of Medicinal Chemistry 94, pages 497-508.
Crossref
Crossref
Anthony J. Roecker, Thomas S. Reger, M. Christa Mattern, Swati P. Mercer, Jeffrey M. Bergman, John D. Schreier, Rowena V. Cube, Christopher D. Cox, Dansu Li, Wei Lemaire, Joseph G. Bruno, C. Meacham Harrell, Susan L. Garson, Anthony L. Gotter, Steven V. Fox, Joanne Stevens, Pamela L. Tannenbaum, Thomayant Prueksaritanont, Tamara D. Cabalu, Donghui Cui, Joyce Stellabott, George D. Hartman, Steven D. Young, Christopher J. Winrow, John J. Renger & Paul J. Coleman. (2014) Discovery of MK-3697: A selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia. Bioorganic & Medicinal Chemistry Letters 24:20, pages 4884-4890.
Crossref
Crossref
Renata Silva, Helena Carmo, Vânia Vilas-Boas, Daniel José Barbosa, Andreia Palmeira, Emília Sousa, Félix Carvalho, Maria de Lourdes Bastos & Fernando Remião. (2014) Colchicine effect on P-glycoprotein expression and activity: In silico and in vitro studies. Chemico-Biological Interactions 218, pages 50-62.
Crossref
Crossref
Andrew A Somogyi, Daniel T Barratt, Robert L Ali & Janet K Coller. (2014) Pharmacogenomics of methadone maintenance treatment. Pharmacogenomics 15:7, pages 1007-1027.
Crossref
Crossref
Donna A. Volpe, Hong Shen & Praveen V. Balimane. 2014. Predictive ADMET. Predictive ADMET
263
290
.
Dan Li, Lei Chen, Youyong Li, Sheng Tian, Huiyong Sun & Tingjun Hou. (2014)
ADMET Evaluation in Drug Discovery. 13. Development of
in Silico
Prediction Models for P-Glycoprotein Substrates
. Molecular Pharmaceutics 11:3, pages 716-726.
Crossref
Crossref
Matthew L. Rizk, Robert Houle, Grace Hoyee Chan, Mike Hafey, Elizabeth G. Rhee & Xiaoyan Chu. (2014)
Raltegravir Has a Low Propensity To Cause Clinical Drug Interactions through Inhibition of Major Drug Transporters: an
In Vitro
Evaluation
. Antimicrobial Agents and Chemotherapy 58:3, pages 1294-1301.
Crossref
Crossref
Sarah E. Lacher, Julia N. Gremaud, Kasse Skagen, Emily Steed, Rachel Dalton, Kent D. Sugden, Fernando Cardozo-Pelaez, Catherine M. T. Sherwin & Erica L. Woodahl. (2014) Absence of P-Glycoprotein Transport in the Pharmacokinetics and Toxicity of the Herbicide Paraquat. Journal of Pharmacology and Experimental Therapeutics 348:2, pages 336-345.
Crossref
Crossref
Tracy A. DeWald & Richard C. Becker. (2013) The pharmacology of novel oral anticoagulants. Journal of Thrombosis and Thrombolysis 37:2, pages 217-233.
Crossref
Crossref
Anthony J. Roecker, Swati P. Mercer, John D. Schreier, Christopher D. Cox, Mark E. Fraley, Justin T. Steen, Wei Lemaire, Joseph G. Bruno, C. Meacham Harrell, Susan L. Garson, Anthony L. Gotter, Steven V. Fox, Joanne Stevens, Pamela L. Tannenbaum, Thomayant Prueksaritanont, Tamara D. Cabalu, Donghui Cui, Joyce Stellabott, George D. Hartman, Steven D. Young, Christopher J. Winrow, John J. Renger & Paul J. Coleman. (2014)
Discovery of 5′′-Chloro-
N
-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia
. ChemMedChem 9:2, pages 311-322.
Crossref
Crossref
Hai-Hong Hu, Yi-Cong Bian, Yao Liu, Rong Sheng, Hui-Di Jiang, Lu-Shan Yu, Yong-Zhou Hu & Su Zeng. (2014) Evaluation of blood?brain barrier and blood?cerebrospinal fluid barrier permeability of 2-phenoxy-indan-1-one derivatives using in vitro cell models. International Journal of Pharmaceutics 460:1-2, pages 101-107.
Crossref
Crossref
Michael D. Reed & Michelle L. Bestic. 2014. Bone Drugs in Pediatrics. Bone Drugs in Pediatrics
5
22
.
Swati P. Mercer, Anthony J. Roecker, Susan Garson, Duane R. Reiss, C. Meacham Harrell, Kathy L. Murphy, Joseph G. Bruno, Rodney A. Bednar, Wei Lemaire, Donghui Cui, Tamara D. Cabalu, Cuyue Tang, Thomayant Prueksaritanont, George D. Hartman, Steven D. Young, Christopher J. Winrow, John J. Renger & Paul J. Coleman. (2013) Discovery of 2,5-diarylnicotinamides as selective orexin-2 receptor antagonists (2-SORAs). Bioorganic & Medicinal Chemistry Letters 23:24, pages 6620-6624.
Crossref
Crossref
J. H. Lewis & J. G. Stine. (2013) Review article: prescribing medications in patients with cirrhosis – a practical guide. Alimentary Pharmacology & Therapeutics 37:12, pages 1132-1156.
Crossref
Crossref
Jeffrey D. Wessler, Laura T. Grip, Jeanne Mendell & Robert P. Giugliano. (2013) The P-Glycoprotein Transport System and Cardiovascular Drugs. Journal of the American College of Cardiology 61:25, pages 2495-2502.
Crossref
Crossref
Prashant V. Desai, Geri A. Sawada, Ian A. Watson & Thomas J. Raub. (2013) Integration of in Silico and in Vitro Tools for Scaffold Optimization during Drug Discovery: Predicting P-Glycoprotein Efflux. Molecular Pharmaceutics 10:4, pages 1249-1261.
Crossref
Crossref
Sook Wah Yee, Deanna L. Kroetz & Kathleen M. Giacomini. 2013. Pharmacogenomics of Human Drug Transporters. Pharmacogenomics of Human Drug Transporters
73
108
.
Yurong Lai. 2013. Transporters in Drug Discovery and Development. Transporters in Drug Discovery and Development
633
674
.
Claudia Suenderhauf, Felix Hammann & Jörg Huwyler. (2012) Computational Prediction of Blood-Brain Barrier Permeability Using Decision Tree Induction. Molecules 17:9, pages 10429-10445.
Crossref
Crossref
E. R. Butelman, M. Caspers, K. M. Lovell, M. J. Kreek & T. E. Prisinzano. (2012) Behavioral Effects and Central Nervous System Levels of the Broadly Available -Agonist Hallucinogen Salvinorin A Are Affected by P-Glycoprotein Modulation In Vivo. Journal of Pharmacology and Experimental Therapeutics 341:3, pages 802-808.
Crossref
Crossref
Alexander V. LyubimovSouzan Yanni & Karel Allegaert. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
44
.
Hanneke G. M. Wittgen, Rick Greupink, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Heike Dinter-Heidorn, Jan B. Koenderink & Frans G. M. Russel. (2012) Exploiting Transport Activity of P-Glycoprotein at the Blood–Brain Barrier for the Development of Peripheral Cannabinoid Type 1 Receptor Antagonists. Molecular Pharmaceutics 9:5, pages 1351-1360.
Crossref
Crossref
Kenneth Bachmann & Sean Ekins. 2012. Predictive Approaches in Drug Discovery and Development. Predictive Approaches in Drug Discovery and Development
307
329
.
Sheila Annie Peters. 2012. Physiologically‐Based Pharmacokinetic (PBPK) Modeling and Simulations. Physiologically‐Based Pharmacokinetic (PBPK) Modeling and Simulations
273
298
.
Joon Hee Park, Jung Hyun Park, Hye Jung Hur, Jong Soo Woo & Hwa Jeong Lee. (2012) Effects of silymarin and formulation on the oral bioavailability of paclitaxel in rats. European Journal of Pharmaceutical Sciences 45:3, pages 296-301.
Crossref
Crossref
Yumiko Akamine, Kayoko China & Tsukasa Uno. (2012) The Role of Drug Transporters on Psychotropic Penetration of the Blood–Brain Barrier. Clinical Neuropsychopharmacology and Therapeutics 3:0, pages 8-14.
Crossref
Crossref
Thomas H. Graham, Hong C. Shen, Wensheng Liu, Yusheng Xiong, Andreas Verras, Kelly Bleasby, Urmi R. Bhatt, Renee M. Chabin, Dunlu Chen, Qing Chen, Margarita Garcia-Calvo, Wayne M. Geissler, Huaibing He, Michael E. Lassman, Zhu Shen, Xinchun Tong, Elaine C. Tung, Dan Xie, Suoyu Xu, Steven L. Colletti, James R. Tata, Jeffrey J. Hale, Shirly Pinto & Dong-Ming Shen. (2012) The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters 22:1, pages 658-665.
Crossref
Crossref
Keith W. Ward. 2014. Reducing Drug Attrition. Reducing Drug Attrition
73
95
.
Sridhar Narayan, Eric M. Carlson, Hongsheng Cheng, Hong Du, Yongbo Hu, Yimin Jiang, Bryan M. Lewis, Boris M. Seletsky, Karen Tendyke, Huiming Zhang, Wanjun Zheng, Bruce A. Littlefield, Murray J. Towle & Melvin J. Yu. (2011) Novel second generation analogs of eribulin. Part I: Compounds containing a lipophilic C32 side chain overcome P-glycoprotein susceptibility. Bioorganic & Medicinal Chemistry Letters 21:6, pages 1630-1633.
Crossref
Crossref
Sridhar Narayan, Eric M. Carlson, Hongsheng Cheng, Krista Condon, Hong Du, Sean Eckley, Yongbo Hu, Yimin Jiang, Vipul Kumar, Bryan M. Lewis, Philip Saxton, Edgar Schuck, Boris M. Seletsky, Karen Tendyke, Huiming Zhang, Wanjun Zheng, Bruce A. Littlefield, Murray J. Towle & Melvin J. Yu. (2011) Novel second generation analogs of eribulin. Part II: Orally available and active against resistant tumors in vivo. Bioorganic & Medicinal Chemistry Letters 21:6, pages 1634-1638.
Crossref
Crossref
Thomas S. Reger, Zhi-Qiang Yang, Kelly-Ann S. Schlegel, Youheng Shu, Christa Mattern, Rowena Cube, Kenneth E. Rittle, Georgia B. McGaughey, George D. Hartman, Cuyue Tang, Jeanine Ballard, Yuhsin Kuo, Thomayant Prueksaritanont, Cindy E. Nuss, Scott M. Doran, Steven V. Fox, Susan L. Garson, Yuxing Li, Richard L. Kraus, Victor N. Uebele, John J. Renger & James C. Barrow. (2011) Pyridyl amides as potent inhibitors of T-type calcium channels. Bioorganic & Medicinal Chemistry Letters 21:6, pages 1692-1696.
Crossref
Crossref
Shuanglian Li, Ying Chen, Shuzhong Zhang, Swati S. More, Xiaozhu Huang & Kathleen M. Giacomini. (2010) Role of Organic Cation Transporter 1, OCT1 in the Pharmacokinetics and Toxicity of cis-Diammine(pyridine)chloroplatinum(II) and Oxaliplatin in Mice. Pharmaceutical Research 28:3, pages 610-625.
Crossref
Crossref
Jack G. Shi, Yan Zhang & Swamy Yeleswaram. (2011) The relevance of assessment of intestinal P-gp inhibition using digoxin as an in vivo probe substrate. Nature Reviews Drug Discovery 10:1, pages 75-75.
Crossref
Crossref
Matthew H. Crouthamel, Daniel Wu, Ziping Yang & Rodney J. Y. Ho. (2010) A Novel MDR1 GT1292-3TG (Cys431Leu) Genetic Variation and Its Effect on P-glycoprotein Biologic Functions. The AAPS Journal 12:4, pages 548-555.
Crossref
Crossref
Dan W. Urry, Kelley D. Urry, Witold Szaflarski & Michal Nowicki. (2010) Elastic-contractile model proteins: Physical chemistry, protein function and drug design and delivery. Advanced Drug Delivery Reviews 62:15, pages 1404-1455.
Crossref
Crossref
R.S. Camenzind, S. Chip, H. Gutmann, J.P. Kapfhammer, C. Nitsch & K. Bendfeldt. (2010) Preservation of transendothelial glucose transporter 1 and P-glycoprotein transporters in a cortical slice culture model of the blood–brain barrier. Neuroscience 170:1, pages 361-371.
Crossref
Crossref
Amin A. Nomeir. 2010. Early Drug Development. Early Drug Development
25
88
.
Paul J. Coleman, John D. Schreier, Anthony J. Roecker, Swati P. Mercer, Georgia B. McGaughey, Christopher D. Cox, George D. Hartman, C. Meacham Harrell, Duane R. Reiss, Scott M. Doran, Susan L. Garson, Wayne B. Anderson, Cuyue Tang, Thomayant Prueksaritanont, Christopher J. Winrow & John J. Renger. (2010) Discovery of 3,9-diazabicyclo[4.2.1]nonanes as potent dual orexin receptor antagonists with sleep-promoting activity in the rat. Bioorganic & Medicinal Chemistry Letters 20:14, pages 4201-4205.
Crossref
Crossref
Joseph D. Ma, Shirley M. Tsunoda, Joseph S. BertinoJrJr, Meghana Trivedi, Keola K. Beale & Anne N. Nafziger. (2010) Evaluation of In Vivo P-Glycoprotein Phenotyping Probes. Clinical Pharmacokinetics 49:4, pages 223-237.
Crossref
Crossref
Paul J. Coleman, John D. Schreier, Georgia B. McGaughey, Michael J. Bogusky, Christopher D. Cox, George D. Hartman, Richard G. Ball, C. Meacham Harrell, Duane R. Reiss, Thomayant Prueksaritanont, Christopher J. Winrow & John J. Renger. (2010) Design and synthesis of conformationally constrained N,N-disubstituted 1,4-diazepanes as potent orexin receptor antagonists. Bioorganic & Medicinal Chemistry Letters 20:7, pages 2311-2315.
Crossref
Crossref
Paul O. Gubbins & Seth Heldenbrand. (2010) Clinically relevant drug interactions of current antifungal agents. Mycoses 53:2, pages 95-113.
Crossref
Crossref
Urban Fagerholm. (2008) Prediction of human pharmacokinetics—biliary and intestinal clearance and enterohepatic circulation. Journal of Pharmacy and Pharmacology 60:5, pages 535-542.
Crossref
Crossref
Birk Poller, Jürgen Drewe, Stephan Krähenbühl, Jörg Huwyler & Heike Gutmann. (2009) Regulation of BCRP (ABCG2) and P-Glycoprotein (ABCB1) by Cytokines in a Model of the Human Blood–Brain Barrier. Cellular and Molecular Neurobiology 30:1, pages 63-70.
Crossref
Crossref
Robert C. Ford, Alhaji B. Kamis, Ian D. Kerr & Richard Callaghan. 2009. Transporters as Drug Carriers. Transporters as Drug Carriers
1
48
.
Shanta M. Messerli, Ravi S. Kasinathan, William Morgan, Stefani Spranger & Robert M. Greenberg. (2009) Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility. Molecular and Biochemical Parasitology 167:1, pages 54-59.
Crossref
Crossref
Fabienne Grandjean‐Forestier, Christophe Stenger, Jacques Robert, Mireille Verdier & Marie‐Hélène Ratinaud. 2009. ABC Transporters and Multidrug Resistance. ABC Transporters and Multidrug Resistance
15
46
.
David B. Whitman, Christopher D. Cox, Michael J. Breslin, Karen M. Brashear, John D. Schreier, Michael J. Bogusky, Rodney A. Bednar, Wei Lemaire, Joseph G. Bruno, George D. Hartman, Duane R. Reiss , C. Meacham Harrell, Richard L. Kraus, Yuxing Li, Susan L. Garson, Scott M. Doran, Thomayant Prueksaritanont, Chunze Li, Christopher J. Winrow, Kenneth S. Koblan, John J. Renger & Paul J. Coleman. (2009)
Discovery of a Potent, CNS-Penetrant Orexin Receptor Antagonist Based on an
N
,
N
-Disubstituted-1,4-diazepane Scaffold that Promotes Sleep in Rats
. ChemMedChem 4:7, pages 1069-1074.
Crossref
Crossref
Paul O. Gubbins & Elias J. Anaissie. 2009. Clinical Mycology. Clinical Mycology
161
195
.
Ziping Yang, Daniel Wu, Tot Bui & Rodney J. Y. Ho. (2008)
A Novel Human Multidrug Resistance Gene
MDR1
Variant
G571A
(G191R) Modulates Cancer Drug Resistance and Efflux Transport
. Journal of Pharmacology and Experimental Therapeutics 327:2, pages 474-481.
Crossref
Crossref
Anika M. S. Hartz, Björn Bauer, Michelle L. Block, Jau-Shyong Hong & David S. Miller. (2008) Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P‐glycoprotein up‐regulation at the blood‐brain barrier. The FASEB Journal 22:8, pages 2723-2733.
Crossref
Crossref
Christopher D. Cox, Paul J. Coleman, Michael J. Breslin, David B. Whitman, Robert M. Garbaccio, Mark E. Fraley, Carolyn A. Buser, Eileen S. Walsh, Kelly Hamilton, Michael D. Schaber, Robert B. Lobell, Weikang Tao, Joseph P. Davide, Ronald E. Diehl, Marc T. Abrams, Vicki J. South, Hans E. Huber, Maricel Torrent, Thomayant Prueksaritanont, Chunze Li, Donald E. Slaughter, Elizabeth Mahan, Carmen Fernandez-Metzler, Youwei Yan, Lawrence C. Kuo, Nancy E. Kohl & George D. Hartman. (2008)
Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2
S
)-4-(2,5-Difluorophenyl)-
N
-[(3
R
,4
S
)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-
N
-methyl-2-phenyl-2,5-dihydro-1
H
-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer
. Journal of Medicinal Chemistry 51:14, pages 4239-4252.
Crossref
Crossref
Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt & Frederick Nelson. (2008) P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model. Drug Metabolism and Disposition 36:6, pages 1073-1079.
Crossref
Crossref
Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto & Yuichi Sugiyama. (2008) Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies. Drug Metabolism and Disposition 36:5, pages 807-810.
Crossref
Crossref
Gergely Szakács, András Váradi, Csilla Özvegy-Laczka & Balázs Sarkadi. (2008) The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox). Drug Discovery Today 13:9-10, pages 379-393.
Crossref
Crossref
Peng Hsiao, Tot Bui, Rodney J. Y. Ho & Jashvant D. Unadkat. (2008) In Vitro-to-in Vivo Prediction of P-glycoprotein-Based Drug Interactions at the Human and Rodent Blood-Brain Barrier. Drug Metabolism and Disposition 36:3, pages 481-484.
Crossref
Crossref
Cristina Rodríguez-Antona, Susanna Leskelä, Magdalena ZajacMarta CuadrosJavier AlvésMaria Victoria Moneo, Carmen Martín, Juan Cruz Cigudosa, Amancio Carnero, Mercedes Robledo, Javier BenitezBeatriz Martínez-Delgado. (2007) Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas. Blood 110:9, pages 3345-3351.
Crossref
Crossref
Francesca Borrelli, Raffaele Capasso & Angelo A. Izzo. (2007) Garlic (Allium sativumL.): Adverse effects and drug interactions in humans. Molecular Nutrition & Food Research 51:11, pages 1386-1397.
Crossref
Crossref
&NA;. (2007) Therapeutic drug monitoring (TDM) and/or pharmacogenetic tests may be useful in devising individualised drug therapy regimens. Drugs & Therapy Perspectives 23:6, pages 22-26.
Crossref
Crossref
Christopher D. Cox, Michael J. Breslin, David B. Whitman, Paul J. Coleman, Robert M. Garbaccio, Mark E. Fraley, Matthew M. Zrada, Carolyn A. Buser, Eileen S. Walsh, Kelly Hamilton, Robert B. Lobell, Weikang Tao, Marc T. Abrams, Vicki J. South, Hans E. Huber, Nancy E. Kohl & George D. Hartman. (2007) Kinesin spindle protein (KSP) inhibitors. Part V: Discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by β-fluorination to overcome cellular efflux by P-glycoprotein. Bioorganic & Medicinal Chemistry Letters 17:10, pages 2697-2702.
Crossref
Crossref
Andrew A Somogyi, Daniel T Barratt & Janet K Coller. (2007) Pharmacogenetics of Opioids. Clinical Pharmacology & Therapeutics 81:3, pages 429-444.
Crossref
Crossref
Masatoshi Masuda & Takaharu Mizutani. (2007) Antigenic Epitopes on Human P-glycoprotein Recognized by Autoimmune Hepatitis Autoantibody as a Case Study. Journal of Health Science 53:3, pages 282-290.
Crossref
Crossref
Valentino J. Stella. 2007. Prodrugs. Prodrugs
37
82
.
Valentino J. Stella. 2007. Prodrugs. Prodrugs
3
33
.
Xavier Declèves, Elisabeth Niel, Marcel Debray & Jean-Michel Scherrmann. (2006) Is P-glycoprotein (ABCB1) a phase 0 or a phase 3 colchicine transporter depending on colchicine exposure conditions?. Toxicology and Applied Pharmacology 217:2, pages 153-160.
Crossref
Crossref
Valerie Gouaze-Andersson & Myles C. Cabot. (2006) Glycosphingolipids and drug resistance. Biochimica et Biophysica Acta (BBA) - Biomembranes 1758:12, pages 2096-2103.
Crossref
Crossref
Matthew H. Crouthamel, Daniel Wu, Ziping Yang & Rodney J.Y. Ho. (2006) A Novel MDR1 G1199T Variant Alters Drug Resistance and Efflux Transport Activity of P-Glycoprotein in Recombinant Hek Cells. Journal of Pharmaceutical Sciences 95:12, pages 2767-2777.
Crossref
Crossref
Balázs Sarkadi, László Homolya, Gergely Szakács & András Váradi. (2006) Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System. Physiological Reviews 86:4, pages 1179-1236.
Crossref
Crossref
Wanlong Jiang, Fabio C. Tucci, Caroline W. Chen, Melissa Arellano, Joe A. Tran, Nicole S. White, Dragan Marinkovic, Joseph Pontillo, Beth A. Fleck, Jenny Wen, John Saunders, Ajay Madan, Alan C. Foster & Chen Chen. (2006) Arylpropionylpiperazines as antagonists of the human melanocortin-4 receptor. Bioorganic & Medicinal Chemistry Letters 16:17, pages 4674-4678.
Crossref
Crossref
Edna F. Choo, Daniel Kurnik, Mordechai Muszkat, Tadashi Ohkubo, Sheila D. Shay, James N. Higginbotham, Hartmut Glaeser, Richard B. Kim, Alastair J. J. Wood & Grant R. Wilkinson. (2006) Differential in Vivo Sensitivity to Inhibition of P-glycoprotein Located in Lymphocytes, Testes, and the Blood-Brain Barrier. Journal of Pharmacology and Experimental Therapeutics 317:3, pages 1012-1018.
Crossref
Crossref
Jennifer S. Sorensen, Michele M. Skopec & M. Denise Dearing. (2006) Application of Pharmacological Approaches to Plant–Mammal Interactions. Journal of Chemical Ecology 32:6, pages 1229-1246.
Crossref
Crossref
Jennifer S. Sorensen & M. Denise Dearing. (2006) Efflux Transporters as a Novel Herbivore Countermechanism to Plant Chemical Defenses. Journal of Chemical Ecology 32:6, pages 1181-1196.
Crossref
Crossref
Rogier R. Press, Tessa Buckle, Jos H. Beijnen & Olaf van Tellingen. (2005) The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in mice. Cancer Chemotherapy and Pharmacology 57:6, pages 819-825.
Crossref
Crossref
Rikiya Ohashi, Yukari Kamikozawa, Mika Sugiura, Hajime Fukuda, Hikaru Yabuuchi & Ikumi Tamai. (2006) EFFECT OF P-GLYCOPROTEIN ON INTESTINAL ABSORPTION AND BRAIN PENETRATION OF ANTIALLERGIC AGENT BEPOTASTINE BESILATE. Drug Metabolism and Disposition 34:5, pages 793-799.
Crossref
Crossref
Scott G. Summerfield, Alexander J. Stevens, Leanne Cutler, Maria del Carmen Osuna, Beverley Hammond, Sac-Pham Tang, Ann Hersey, David J. Spalding & Phil Jeffrey. (2006) Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and Brain. Journal of Pharmacology and Experimental Therapeutics 316:3, pages 1282-1290.
Crossref
Crossref
Gergely Szakács, Jill K. Paterson, Joseph A. Ludwig, Catherine Booth-Genthe & Michael M. Gottesman. (2006) Targeting multidrug resistance in cancer. Nature Reviews Drug Discovery 5:3, pages 219-234.
Crossref
Crossref
Thomas J. Raub. (2005) P-Glycoprotein Recognition of Substrates and Circumvention through Rational Drug Design. Molecular Pharmaceutics 3:1, pages 3-25.
Crossref
Crossref
Jiang-shu JIN, Toshiyuki SAKAEDA, Mikio KAKUMOTO, Kohshi NISHIGUCHI, Tsutomu NAKAMURA, Noboru OKAMURA & Katsuhiko OKUMURA. (2006) Effect of Therapeutic Moderate Hypothermia on Multi-drug Resistance Protein 1-Mediated Transepithelial Transport of Drugs. Neurologia medico-chirurgica 46:7, pages 321-327.
Crossref
Crossref
Eveline Jaquenoud Sirot, Jan Willem van der Velden, Katharina Rentsch, Chin B Eap & Pierre Baumann. (2006) Therapeutic Drug Monitoring and Pharmacogenetic Tests as Tools in Pharmacovigilance. Drug Safety 29:9, pages 735-768.
Crossref
Crossref
David E. Modrak, Graham K. Jones & Michael P. Draper. 2005. Frontiers in Antimicrobial Resistance. Frontiers in Antimicrobial Resistance
500
513
.
Yasumasa Gotoh, Noboru Kamada & Denichi Momose. (2005) The Advantages of the Ussing Chamber in Drug Absorption Studies. SLAS Discovery 10:5, pages 517-523.
Crossref
Crossref
Timothy J. C. Anderson, Shalini Nair, Huang Qin, Sittaporn Singlam, Alan Brockman, Lucy Paiphun & François Nosten. (2005)
Are Transporter Genes Other than the Chloroquine Resistance Locus (
pfcrt
) and Multidrug Resistance Gene (
pfmdr
) Associated with Antimalarial Drug Resistance?
. Antimicrobial Agents and Chemotherapy 49:6, pages 2180-2188.
Crossref
Crossref
Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc & Jeffery Van Deusen. (2005) Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding. Journal of Pharmacology and Experimental Therapeutics 313:3, pages 1254-1262.
Crossref
Crossref
Sumio Ohtsuki, Naoko Kamiya, Satoko Hori & Tetsuya Terasaki. (2005) Vascular EndotheliumSelective Gene Induction by Tie2 Promoter/Enhancer in the Brain and Retina of a Transgenic Rat. Pharmaceutical Research 22:6, pages 852-857.
Crossref
Crossref
Steven Gabardi & Stuart Abramson. (2005) Drug Dosing in Chronic Kidney Disease. Medical Clinics of North America 89:3, pages 649-687.
Crossref
Crossref
Y.A. Luqmani. (2005) Mechanisms of Drug Resistance in Cancer Chemotherapy. Medical Principles and Practice 14:1, pages 35-48.
Crossref
Crossref
Robert Z. Orlowski. 2005. Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases. Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
243
274
.
Tanios S. Bekaii‐Saab, Michael D. Perloff, James L. Weemhoff, David J. Greenblatt & Lisa L. von Moltke. (2004) Interactions of tamoxifen, N‐desmethyltamoxifen and 4‐hydroxytamoxifen with P‐glycoprotein and CYP3A. Biopharmaceutics & Drug Disposition 25:7, pages 283-289.
Crossref
Crossref
Andrew Collett, Jolanta Tanianis-Hughes & Geoff Warhurst. (2004) Rapid induction of P-glycoprotein expression by high permeability compounds in colonic cells in vitro: a possible source of transporter mediated drug interactions?. Biochemical Pharmacology 68:4, pages 783-790.
Crossref
Crossref