Drug Metabolism Reviews, Volume 35, Issue 4 (2003)

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Drug Metabolism Reviews, Volume 35, Issue 4 (2003)

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Research Article

Article
Pathophysiological Factors Affecting CAR Gene Expression
Jean Marc Pascussi, Zdenek Dvorák, Sabine Gerbal-Chaloin, Eric Assenat, Patrick Maurel & Marie José Vilarem
Pages: 255-268
Published online: 12 Aug 2003
AbstractforPathophysiological Factors Affecting CAR Gene Expression | Full Text | References | PDF (269.6 KB)
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Article
Early Drug Safety Evaluation: Biomarkers, Signatures, and Fingerprints
Ruth Roberts, Kelvin Cain, Beth Coyle, Caroline Freathy, Jean-Francois Leonard & Jean-Charles Gautier
Pages: 269-275
Published online: 12 Aug 2003
AbstractforEarly Drug Safety Evaluation: Biomarkers, Signatures, and Fingerprints | Full Text | References | PDF (284.7 KB)
  • 60 Views
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Article
Clinical Relevance of Pharmacogenetics
Laurent Becquemont
Pages: 277-285
Published online: 12 Aug 2003
AbstractforClinical Relevance of Pharmacogenetics | Full Text | References | PDF (185.4 KB)
  • 115 Views
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Article
The Human UDP-Glucuronosyltransferases: Structural Aspects and Drug Glucuronidation
Mohamed Ouzzine, Lydia Barré, Patrick Netter, Jacques Magdalou & Sylvie Fournel-Gigleux
Pages: 287-303
Published online: 12 Aug 2003
First Page PreviewforThe Human UDP-Glucuronosyltransferases: Structural Aspects and Drug Glucuronidation | Full Text | References | PDF (390.4 KB)
  • 281 Views
  • 54 CrossRef citations
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Article
Regulation of Drug and Bile Salt Transporters in Liver and Intestine
Gerd A. Kullak-Ublick M.D. & May-Britt Becker
Pages: 305-317
Published online: 12 Aug 2003
AbstractforRegulation of Drug and Bile Salt Transporters in Liver and Intestine | Full Text | References | PDF (261.2 KB)
  • 456 Views
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Article
Role of Gene Knockout and Transgenic Mice in the Study of Xenobiotic Metabolism
Frank J. Gonzalez
Pages: 319-335
Published online: 12 Aug 2003
AbstractforRole of Gene Knockout and Transgenic Mice in the Study of Xenobiotic Metabolism | Full Text | References | PDF (375.6 KB)
  • 225 Views
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Article
Chemical-Induced Apoptosis: Formation of the Apaf-1 Apoptosome
Kelvin Cain
Pages: 337-363
Published online: 12 Aug 2003
AbstractforChemical-Induced Apoptosis: Formation of the Apaf-1 Apoptosome | Full Text | References | PDF (770.8 KB)
  • 459 Views
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Article
The Telltale Structures of Epoxide Hydrolases
Michael Arand, Annette Cronin, Franz Oesch, Sherry L. Mowbray & T. Alwyn Jones
Pages: 365-383
Published online: 12 Aug 2003
AbstractforThe Telltale Structures of Epoxide Hydrolases | Full Text | References | PDF (502.1 KB)
  • 324 Views
  • 55 CrossRef citations
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Article
Knockout Mice in Xenobiotic Metabolism
Colin J. Henderson, Diana M. E. Otto, Aileen W. McLaren, Dianne Carrie & C. Roland Wolf
Pages: 385-392
Published online: 12 Aug 2003
First Page PreviewforKnockout Mice in Xenobiotic Metabolism | Full Text | References | PDF (367.8 KB)
  • 85 Views
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Article
Progress Towards Prediction of Human Pharmacokinetic Parameters from In Vitro Technologies
J. Brian Houston & Aleksandra Galetin
Pages: 393-415
Published online: 12 Aug 2003
AbstractforProgress Towards Prediction of Human Pharmacokinetic Parameters from In Vitro Technologies | Full Text | References | PDF (1 MB)
  • 251 Views
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Article
Clinical Relevance of P-Glycoprotein in Drug Therapy
Jiunn H. Lin & Masayo Yamazaki
Pages: 417-454
Published online: 12 Aug 2003
AbstractforClinical Relevance of P-Glycoprotein in Drug Therapy | Full Text | References | PDF (645.1 KB)
  • 525 Views
  • 140 CrossRef citations
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