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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 12
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Original Articles

One Pot Synthesis of 4(3H)‐Quinazolinones

Bashir A. Bhat Chemical Technology Division, Central Drug Research Institute, Lucknow, 226001, India
&
Devi P. Sahu Chemical Technology Division, Central Drug Research Institute, Lucknow, 226001, IndiaCorrespondence[email protected]
Pages 2169-2176 | Received 09 Feb 2004, Published online: 17 Aug 2006

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Samir Y. Abbas, Khairy A. M. El-Bayouki & Wahid M. Basyouni. (2016) Utilization of isatoic anhydride in the syntheses of various types of quinazoline and quinazolinone derivatives. Synthetic Communications 46:12, pages 993-1035.
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Navjeet Kaur. (2015) Applications of Microwaves in the Synthesis of Polycyclic Six-Membered N,N-Heterocycles. Synthetic Communications 45:14, pages 1599-1631.
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Seyed Mostafa Ebrahimi, Mohammad Mahdavi, Saeed Emami, Mina Saeedi, Mehdi Asadi, Loghman Firoozpour, Mehdi Khoobi, Kouros Divsalar, Abbas Shafiee & Alireza Foroumadi. (2014) Green and Catalyst-Free One-Pot Synthesis of Anthranilamide Schiff Bases: An Approach Toward Sirtinol. Synthetic Communications 44:5, pages 665-673.
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MahmoudR. Mahmoud & HamedA. Y. Derbala. (2010) Heteroannulated Quinazoline and Quinazolinone Derivatives from (Z)-2-[1-Benzamido-2-(3,4,5-trimethoxyphenyl)]vinyl-3,1-benzoxazin-4(3H)-one. Synthetic Communications 40:10, pages 1516-1529.
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Shashikanth Ponnala & Devi Prasad Sahu. (2006) Iodine‐Mediated Synthesis of 2‐Arylbenzoxazoles, 2‐Arylbenzimidazoles, and 1,3,5‐Trisubstituted Pyrazoles. Synthetic Communications 36:15, pages 2189-2194.
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Akichika Itoh, Norihiro Tada & Eiji Yamaguchi. (2023) Development of Novel Molecular Transformation Reactions Using Iodine Driven by Photochemical Activation光化学的活性化を駆動力としたヨウ素を利用する新規分子変換反応の開発. Journal of Synthetic Organic Chemistry, Japan 81:5, pages 451-462.
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Anjitha Satheesh, Gopika Gokuldas, Krishnan M. Gayathri & Elango Kandasamy. (2022) Effect of Solvents on 1-Butyl-1,2,4-Triazolium Trifluoroacetate Triggered Synthesis of 2,3-Dihydroquinazolin. Current Organocatalysis 9:4, pages 346-354.
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Ester Colarusso, Erica Gazzillo, Eleonora Boccia, Assunta Giordano, Maria Giovanna Chini, Giuseppe Bifulco & Gianluigi Lauro. (2022) 6‐Methylquinazolin‐4(3 H )‐one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis . European Journal of Organic Chemistry 2022:35.
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Hue Thi Buu Bui, Kiep Minh Do, Huy Tran Duc Nguyen, Hieu Van Mai, Thanh La Duc Danh, De Quang Tran & Hiroyuki Morita. (2021) Efficient one-pot tandem synthesis and cytotoxicity evaluation of 2,3-disubstituted quinazolin-4(3H)-one derivatives. Tetrahedron 98, pages 132426.
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Zhiming Xing, Wanhui Wu, Yongxiang Miao, Yingqun Tang, Youkang Zhou, Lifang Zheng, Yang Fu, Zhibin Song & Yiyuan Peng. (2021) Recent advances in quinazolinones as an emerging molecular platform for luminescent materials and bioimaging. Organic Chemistry Frontiers 8:8, pages 1867-1889.
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Mohammad Sadegh Asgari, Saeed Bahadorikhalili, Rahmatollah Rahimi & Mohammad Mahdavi. (2021) Copper Supported onto Magnetic Nanoparticles as an Efficient Catalyst for the Synthesis of Triazolobenzodiazepino[7,1‐ b ]quinazolin‐11(9 H )‐ones via Click N ‐Arylation Reactions . ChemistrySelect 6:6, pages 1385-1392.
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Kavitha Donthiboina, Geeta Sai Mani, Nagula Shankaraiah & Ahmed Kamal. (2020) Iodine‐Mediated Oxidative Annulation by C–C Cleavage: A Domino Synthetic Approach to Quinazolinones and Benzo[4,5]imidazo[1,2‐ c ]quinazolines . ChemistrySelect 5:13, pages 3923-3928.
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Abbasian Sepideh, Kabirifard Hassan & Mahdavi Mohammad. (2020) Pd-Catalyzed Carbonylation-cyclization of N′-(2-bromophenyl)benzamidines by Chloroform as a CO Precursor for the Synthesis of Quinazolin- 4(3H)-ones. Letters in Organic Chemistry 17:4, pages 303-308.
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Xiaofei Yue, Zhiqiang Wu, Gang Wang, Yanping Liang, Yanyan Sun, Manrong Song, Haijuan Zhan, Shuxian Bi & Wanyi Liu. (2019) High acidity cellulose sulfuric acid from sulfur trioxide: a highly efficient catalyst for the one step synthesis of xanthene and dihydroquinazolinone derivatives. RSC Advances 9:49, pages 28718-28723.
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Huaiyuan Kang, Weili Wang, Qinqiang Sun, Shuya Yang, Juan Jin, Xuewen Zhang, Xiaoliang Ren, Jiming Zhang & Jianhua Zhou. (2018) Microwave-assisted synthesis of quinazolin-4(3 H )-ones catalyzed by SbCl 3 . Heterocyclic Communications 24:6, pages 293-296.
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Chao Wang, Yun Li, Jianfei Zhao, Bin Cheng, Huifei Wang & Hongbin Zhai. (2016) An environmentally friendly approach to pyrrolo[1,2-a]quinoxalines using oxygen as the oxidant. Tetrahedron Letters 57:35, pages 3908-3911.
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Zhen-zhen Wang & Yu Tang. (2016) Mechanistic insights into a catalyst-free method to construct quinazolinones through multiple oxidative cyclization. Tetrahedron 72:10, pages 1330-1336.
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Vu T. Nguyen, Huy Q. Ngo, Dung T. Le, Thanh Truong & Nam T.S. Phan. (2016) Iron-catalyzed domino sequences: One-pot oxidative synthesis of quinazolinones using metal–organic framework Fe 3 O(BPDC) 3 as an efficient heterogeneous catalyst. Chemical Engineering Journal 284, pages 778-785.
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Julien Godeau, Marine Harari, Sylvain Laclef, Emmanuel Deau, Corinne Fruit & Thierry Besson. (2015) Cu/Pd‐Catalyzed C‐2–H Arylation of ­Quinazolin‐4(3 H )‐ones with (Hetero)aryl Halides . European Journal of Organic Chemistry 2015:35, pages 7705-7717.
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Krishnan Revathy & Appaswami Lalitha. (2015) p-TSA-catalyzed synthesis of spiroquinazolinones. Journal of the Iranian Chemical Society 12:11, pages 2045-2049.
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Dezhi Qiu, Yanyan Wang, Dongming Lu, Lihong Zhou & Qingle Zeng. (2015) Potassium hydroxide-promoted transition-metal-free synthesis of 4(3H)-quinazolinones. Monatshefte für Chemie - Chemical Monthly 146:8, pages 1343-1347.
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Teruyuki Kondo, Tsutomu Yoshimura, Di Yuanjun, Yu Kimura, Hisatsugu Yamada & Akio Toshimitsu. (2015) Simple, Selective, and Practical Synthesis of 2-Substituted 4(3H)-Quinazolinones by Yb(OTf)3-Catalyzed Condensation of 2-Aminobenzamide with Carboxamides. HETEROCYCLES 90:2, pages 857.
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Xianhai Tian, Lina Song, Ertong Li, Qiang Wang, Wenquan Yu & Junbiao Chang. (2015) Metal-free one-pot synthesis of 1,3-diazaheterocyclic compounds via I 2 -mediated oxidative C–N bond formation . RSC Advances 5:76, pages 62194-62201.
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Y. Nagasawa, Y. Matsusaki, T. Nobuta, N. Tada, T. Miura & A. Itoh. (2015) Aerobic photooxidative synthesis of 2-aryl-4-quinazolinones from aromatic aldehydes and aminobenzamide using catalytic amounts of molecular iodine. RSC Advances 5:78, pages 63952-63954.
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Yong Zheng, Wei-Bin Song, Shu-Wei Zhang & Li-Jiang Xuan. (2015) Ruthenium-catalyzed oxidative coupling of 2-aryl-4-quinazolinones with olefins: synthesis of pyrrolo[2,1-b]quinazolin-9(1H)-one motifs. Organic & Biomolecular Chemistry 13:23, pages 6474-6478.
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Marjan Heidary, Mehdi Khoobi, Sabrieh Ghasemi, Zohreh Habibi & Mohammad Ali Faramarzi. (2014) Synthesis of Quinazolinones from Alcohols via Laccase‐Mediated Tandem Oxidation . Advanced Synthesis & Catalysis 356:8, pages 1789-1794.
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Li‐Xia Wang, Jun‐Feng Xiang & Ya‐Lin Tang. (2014) Copper‐Catalyzed Domino Reaction Involving C–C Bond Cleavage To Construct 2‐Aryl Quinazolinones. European Journal of Organic Chemistry 2014:13, pages 2682-2685.
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Na Yeun Kim & Cheol-Hong Cheon. (2014) Synthesis of quinazolinones from anthranilamides and aldehydes via metal-free aerobic oxidation in DMSO. Tetrahedron Letters 55:15, pages 2340-2344.
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Hongxin Chai, Jiarong Li, Liupan Yang, Hongyan Lu, Zhang Qi & Daxin Shi. (2014) Copper-catalyzed tandem N-arylation/condensation: synthesis of quinazolin-4(3H)-ones from 2-halobenzonitriles and amides. RSC Adv. 4:84, pages 44811-44814.
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Ran Cheng, Linlin Tang, Tianjian Guo, Daisy Zhang-Negrerie, Yunfei DuKang Zhao. (2014) Oxidant- and metal-free synthesis of 4(3H)-quinazolinones from 2-amino-N-methoxybenzamides and aldehydes via acid-promoted cyclocondensation and elimination. RSC Adv. 4:50, pages 26434-26438.
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Mahmood Tajbakhsh, Rahman Hosseinzadeh, Parizad Rezaee & Mahgol Tajbakhsh. (2014) H3PW12O40 catalyzed synthesis of benzoxazine and quinazoline in aqueous media. Chinese Journal of Catalysis 35:1, pages 58-65.
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Jagannath Jadhav, Sharanabasappa Khanapure, Rajashri Salunkhe & Gajanan Rashinkar. (2013) Cp 2 ZrCl 2 -catalyzed synthesis of 2-substituted quinozolin-4(3 H )-ones . Applied Organometallic Chemistry 27:8, pages 486-488.
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